iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
FBgn0015803	FBtr0336748	FBpp0307724
FBgn0015803	FBtr0336747	FBpp0307723
FBgn0015803	FBtr0112885	FBpp0111798
FBgn0015803	FBtr0081356	FBpp0080888
FBgn0015803	FBtr0336749	FBpp0307725
FBgn0015803	FBtr0302106	FBpp0291316

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	PINA
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.30e-15	55.8	6	59

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           +vq+ y+++++n+deL ++kGdv++v   + +d+gW++g  +l+ k G fP+n+v++ 
   Q: 6    VVQAEYSFMGSNNDELCFQKGDVITVT--QREDGGWWEG--TLNDKTGWFPSNYVNEC 59
           799***********************7..999*******..8*************985 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MDQPLVVQAE YSFMGSNNDE LCFQKGDVIT VTQREDGGWW EGTLNDKTGW FPSNYVNECK 60
VQLPLTETIR PPEEIQEYRS VVLKDLLDSE RAHVAELQGL LENFLEPMQQ TQILSQDEYA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACACATCTTT AGTTTGGCTG CGGCCGATTG CAGCCCTGGT TTTCTAGGTT TCTATTTTGG 60
TCGAGCGCTG TGTTTTATTT ATGTTTGCCA TGGGAAAAGA GAGTTGCTAA AAGTGCCTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR000219--DH-domain
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00621--RhoGEF
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0097482--C:muscle cell postsynaptic density
GO:0005085--F:guanyl-nucleotide exchange factor activity
GO:0032947--F:protein complex scaffold
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0043547--P:positive regulation of GTPase activity
GO:0035332--P:positive regulation of hippo signaling
GO:0046620--P:regulation of organ growth
GO:0035023--P:regulation of Rho protein signal transduction
GO:0050807--P:regulation of synapse organization

KEGG

dme:Dmel_CG10043

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001259	Ailuropoda melanoleuca	45.34	3.00e-103	368.00
IUUC-Apl-003960	Anas platyrhynchos	44.09	5.00e-95	341.00
IUUC-Aca-004591	Anolis carolinensis	44.58	9.00e-102	363.00
IUUC-Afl-008481	Aspergillus flavus	25.10	2.00e-07	50.40
IUUC-Afu-009099	Aspergillus fumigatus	22.29	2.00e-10	60.80
IUUC-Ani-009276	Aspergillus nidulans	24.70	7.00e-12	65.50
IUUC-Ang-009549	Aspergillus niger	26.59	8.00e-13	68.60
IUUC-Aor-010216	Aspergillus oryzae	25.10	2.00e-07	50.40
IUUC-Ate-010338	Aspergillus terreus	24.70	6.00e-10	59.30
IUUC-Ame-011729	Astyanax mexicanus	45.48	4.00e-89	321.00
IUUC-Bta-013328	Bos taurus	45.75	8.00e-104	370.00
IUUC-Cja-018742	Callithrix jacchus	45.09	2.00e-102	365.00
IUUC-Cfa-020756	Canis familiaris	45.09	5.00e-102	364.00
IUUC-Cpo-021284	Cavia porcellus	45.99	6.00e-97	347.00
IUUC-Csa-023162	Chlorocebus sabaeus	45.34	9.00e-103	367.00
IUUC-Cho-024736	Choloepus hoffmanni	51.05	6.00e-42	164.00
IUUC-Cin-025535	Ciona intestinalis	36.20	5.00e-70	257.00
IUUC-Cne-026866	Cryptococcus neoformans	43.14	5.00e-11	63.50
IUUC-Dre-028845	Danio rerio	42.93	3.00e-98	352.00
IUUC-Dno-029461	Dasypus novemcinctus	45.34	3.00e-102	365.00
IUUC-Dor-030623	Dipodomys ordii	39.55	7.00e-80	291.00
IUUC-Ete-032236	Echinops telfairi	39.25	1.00e-84	306.00
IUUC-Eca-034137	Equus caballus	44.94	5.00e-103	368.00
IUUC-Eeu-035269	Erinaceus europaeus	40.86	2.00e-35	143.00
IUUC-Fca-035742	Felis catus	44.84	7.00e-97	347.00
IUUC-Fal-037205	Ficedula albicollis	46.77	8.00e-105	373.00
IUUC-Gmo-039475	Gadus morhua	45.08	5.00e-99	354.00
IUUC-Gga-040539	Gallus gallus	46.35	3.00e-105	375.00
IUUC-Gac-042615	Gasterosteus aculeatus	44.22	2.00e-87	316.00
IUUC-Ggo-044470	Gorilla gorilla	45.59	4.00e-103	368.00
IUUC-Hsa-046398	Homo sapiens	45.59	3.00e-103	368.00
IUUC-Lch-049517	Latimeria chalumnae	44.24	6.00e-99	354.00
IUUC-Lpe-051218	Leersia perrieri	33.33	6.00e-02	28.90
IUUC-Loc-052146	Lepisosteus oculatus	45.48	2.00e-103	369.00
IUUC-Lma-052955	Leptosphaeria maculans	25.50	4.00e-12	66.60
IUUC-Laf-053891	Loxodonta africana	45.09	1.00e-102	366.00
IUUC-Mcc-055483	Macaca mulatta	45.34	9.00e-103	367.00
IUUC-Meu-056285	Macropus eugenii	42.57	4.00e-64	238.00
IUUC-Mga-059410	Meleagris gallopavo	45.59	2.00e-103	369.00
IUUC-Mmr-060758	Microcebus murinus	44.84	2.00e-89	323.00
IUUC-Mdo-061900	Monodelphis domestica	44.84	5.00e-102	364.00
IUUC-Mmu-063849	Mus musculus	46.25	9.00e-98	350.00
IUUC-Mpu-065876	Mustela putorius furo	44.58	5.00e-101	361.00
IUUC-Mlu-067970	Myotis lucifugus	46.25	2.00e-102	366.00
IUUC-Nfi-068331	Neosartorya fischeri	23.79	6.00e-10	59.30
IUUC-Nle-069685	Nomascus leucogenys	45.34	4.00e-103	367.00
IUUC-Opr-071132	Ochotona princeps	38.02	1.00e-64	239.00
IUUC-Ont-071815	Oreochromis niloticus	45.50	3.00e-101	362.00
IUUC-Oan-073057	Ornithorhynchus anatinus	44.96	1.00e-100	359.00
IUUC-Ocu-074852	Oryctolagus cuniculus	42.97	5.00e-97	348.00
IUUC-Ola-086663	Oryzias latipes	44.73	7.00e-100	357.00
IUUC-Oga-088103	Otolemur garnettii	44.89	3.00e-89	322.00
IUUC-Oar-089339	Ovis aries	43.04	8.00e-96	343.00
IUUC-Ptr-091162	Pan troglodytes	45.59	2.00e-103	369.00
IUUC-Pan-092666	Papio anubis	43.72	3.00e-96	345.00
IUUC-Psi-093116	Pelodiscus sinensis	45.41	7.00e-100	357.00
IUUC-Pma-094261	Petromyzon marinus	42.33	2.00e-69	254.00
IUUC-Ppa-095161	Physcomitrella patens	43.75	5.00e-08	51.20
IUUC-Pfo-096736	Poecilia formosa	45.13	3.00e-99	355.00
IUUC-Pab-097641	Pongo abelii	45.34	5.00e-103	367.00
IUUC-Pca-100997	Procavia capensis	37.50	5.00e-75	275.00
IUUC-Pva-102819	Pteropus vampyrus	44.96	4.00e-99	355.00
IUUC-Ptt-103726	Puccinia triticina	41.67	1.00e-09	55.80
IUUC-Pte-104293	Pyrenophora teres	25.81	2.00e-11	64.30
IUUC-Pyt-104722	Pyrenophora triticirepentis	26.21	8.00e-12	65.10
IUUC-Rno-106099	Rattus norvegicus	46.25	1.00e-97	350.00
IUUC-Sha-106845	Sarcophilus harrisii	44.33	2.00e-101	362.00
IUUC-Ssl-108541	Sclerotinia sclerotiorum	24.39	2.00e-10	61.20
IUUC-Sar-113420	Sorex araneus	43.04	2.00e-87	316.00
IUUC-Ssc-116036	Sus scrofa	45.89	9.00e-105	373.00
IUUC-Tgu-117498	Taeniopygia guttata	45.84	2.00e-104	373.00
IUUC-Tru-118278	Takifugu rubripes	44.87	3.00e-101	362.00
IUUC-Tsy-118990	Tarsius syrichta	44.58	6.00e-100	357.00
IUUC-Tni-120852	Tetraodon nigroviridis	43.59	5.00e-97	348.00
IUUC-Tvi-122300	Trichoderma virens	24.70	3.00e-11	63.90
IUUC-Tme-127216	Tuber melanosporum	24.38	7.00e-14	72.00
IUUC-Tbe-127994	Tupaia belangeri	35.60	1.00e-65	243.00
IUUC-Ttr-128922	Tursiops truncatus	44.44	2.00e-94	339.00
IUUC-Vpa-130144	Vicugna pacos	43.78	3.00e-60	226.00
IUUC-Xtr-132012	Xenopus tropicalis	46.13	1.00e-95	343.00
IUUC-Xma-133901	Xiphophorus maculatus	42.82	1.00e-93	337.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence