iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000035735.3	ENSBTAT00000050220.3	ENSBTAP00000046955.3
ENSBTAG00000035735.3	ENSBTAT00000063174.1	ENSBTAP00000054279.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	88.61	0.00e+00	960.00	IUUC-Hsa-045769

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Bos taurus

Protein Sequence
(Fasta)

XRAGFYYTGV NDKVKCFCCG LMLDNWKQGD NPIEKHKQLY PSCSFIQNLV SVTSLESTSK 60
NASSPMRNSF THSLSPTLEH GRSFSGSYSN LSPNPINSRA VEDFSPLRTN PYSYAMSTEE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NCTCGTGCTG GTTTTTATTA CACTGGTGTG AATGACAAGG TCAAATGCTT CTGTTGTGGC 60
CTGATGCTGG ATAACTGGAA ACAAGGAGAC AATCCTATTG AGAAGCATAA ACAACTGTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR028795--C-IAP1
IPR001315--CARD
IPR011029--DEATH-like_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01282--BIR_REPEAT_1
PS50143--BIR_REPEAT_2
PS50209--CARD
PS50089--ZF_RING_2

Pfam

PF00653--BIR
PF00619--CARD

SMART

SM00238--BIR
SM00114--CARD
SM00184--RING

Gene Ontology

GO:0003713--F:transcription coactivator activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0043066--P:negative regulation of apoptotic process
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0000209--P:protein polyubiquitination
GO:0051726--P:regulation of cell cycle
GO:0045595--P:regulation of cell differentiation
GO:0050727--P:regulation of inflammatory response
GO:0060544--P:regulation of necroptotic process
GO:0034121--P:regulation of toll-like receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002369	Ailuropoda melanoleuca	88.47	0.00e+00	978.00
IUUC-Apl-003549	Anas platyrhynchos	70.36	0.00e+00	784.00
IUUC-Aca-004515	Anolis carolinensis	67.56	0.00e+00	740.00
IUUC-Aly-006460	Arabidopsis lyrata	32.39	1.00e-09	57.00
IUUC-Ani-009424	Aspergillus nidulans	31.03	7.00e-14	72.80
IUUC-Ang-009667	Aspergillus niger	31.29	1.00e-12	68.60
IUUC-Ate-010501	Aspergillus terreus	32.52	6.00e-15	76.30
IUUC-Ame-011877	Astyanax mexicanus	55.94	1.00e-176	613.00
IUUC-Cja-018895	Callithrix jacchus	88.99	0.00e+00	935.00
IUUC-Cfa-020419	Canis familiaris	88.97	0.00e+00	978.00
IUUC-Cpo-022048	Cavia porcellus	87.86	0.00e+00	956.00
IUUC-Cho-024277	Choloepus hoffmanni	85.35	0.00e+00	894.00
IUUC-Cin-025521	Ciona intestinalis	29.73	7.00e-68	251.00
IUUC-Cne-027029	Cryptococcus neoformans	30.86	7.00e-12	65.50
IUUC-Dre-028647	Danio rerio	56.06	3.00e-172	598.00
IUUC-Dor-030796	Dipodomys ordii	70.73	8.00e-93	334.00
IUUC-Eca-033393	Equus caballus	93.31	0.00e+00	1001.00
IUUC-Eeu-035114	Erinaceus europaeus	85.71	0.00e+00	897.00
IUUC-Fca-036034	Felis catus	88.79	0.00e+00	951.00
IUUC-Fal-037656	Ficedula albicollis	69.46	0.00e+00	772.00
IUUC-Fox-037889	Fusarium oxysporum	31.61	9.00e-16	79.30
IUUC-Fso-038452	Fusarium solani	31.98	4.00e-14	73.90
IUUC-Gmo-038477	Gadus morhua	54.53	9.00e-167	580.00
IUUC-Gga-040601	Gallus gallus	70.89	0.00e+00	791.00
IUUC-Gac-041467	Gasterosteus aculeatus	55.46	5.00e-168	584.00
IUUC-Ggo-044857	Gorilla gorilla	89.51	0.00e+00	948.00
IUUC-Hsa-045769	Homo sapiens	89.87	0.00e+00	952.00
IUUC-Itr-048441	Ictidomys tridecemlineatus	86.82	0.00e+00	970.00
IUUC-Lch-050259	Latimeria chalumnae	61.48	0.00e+00	674.00
IUUC-Loc-052169	Lepisosteus oculatus	54.39	3.00e-156	545.00
IUUC-Laf-053449	Loxodonta africana	86.85	0.00e+00	918.00
IUUC-Meu-056241	Macropus eugenii	66.60	0.00e+00	651.00
IUUC-Mor-057252	Magnaporthe oryzae	35.22	3.00e-17	84.00
IUUC-Mga-059947	Meleagris gallopavo	70.89	0.00e+00	790.00
IUUC-Mdo-062352	Monodelphis domestica	77.98	0.00e+00	829.00
IUUC-Mmu-064340	Mus musculus	81.80	0.00e+00	876.00
IUUC-Mpu-065890	Mustela putorius furo	86.44	0.00e+00	937.00
IUUC-Mlu-068077	Myotis lucifugus	89.17	0.00e+00	994.00
IUUC-Ncr-068787	Neurospora crassa	32.28	3.00e-13	70.90
IUUC-Nle-070081	Nomascus leucogenys	89.69	0.00e+00	952.00
IUUC-Opr-070561	Ochotona princeps	83.00	0.00e+00	870.00
IUUC-Ont-071776	Oreochromis niloticus	53.90	1.00e-170	593.00
IUUC-Ocu-073963	Oryctolagus cuniculus	88.07	0.00e+00	934.00
IUUC-Ogu-078452	Oryza glumaepatula	45.45	5.00e-07	48.90
IUUC-Oni-082044	Oryza nivara	41.82	3.00e-09	56.60
IUUC-Opu-084085	Oryza punctata	39.58	2.00e-06	46.60
IUUC-Oru-085060	Oryza rufipogon	44.19	1.00e-06	47.80
IUUC-Ola-086446	Oryzias latipes	52.29	5.00e-162	564.00
IUUC-Oga-087976	Otolemur garnettii	89.33	0.00e+00	954.00
IUUC-Oar-090097	Ovis aries	95.68	0.00e+00	1062.00
IUUC-Ptr-091137	Pan troglodytes	90.05	0.00e+00	953.00
IUUC-Pan-092673	Papio anubis	91.14	0.00e+00	963.00
IUUC-Pma-094277	Petromyzon marinus	39.46	1.00e-109	390.00
IUUC-Pfo-096790	Poecilia formosa	53.90	2.00e-165	576.00
IUUC-Pab-098734	Pongo abelii	89.15	0.00e+00	954.00
IUUC-Pop-098944	Populus trichocarpa	35.63	5.00e-10	58.50
IUUC-Pca-100708	Procavia capensis	70.59	5.00e-169	587.00
IUUC-Pva-102788	Pteropus vampyrus	90.96	0.00e+00	961.00
IUUC-Pyt-104561	Pyrenophora triticirepentis	34.59	1.00e-14	74.30
IUUC-Rno-105026	Rattus norvegicus	78.84	0.00e+00	861.00
IUUC-Sja-107720	Schizosaccharomyces japonicus	34.23	5.00e-16	80.10
IUUC-Ssc-115804	Sus scrofa	88.81	0.00e+00	969.00
IUUC-Tgu-116931	Taeniopygia guttata	70.18	0.00e+00	787.00
IUUC-Tru-117620	Takifugu rubripes	54.25	4.00e-167	581.00
IUUC-Tni-119683	Tetraodon nigroviridis	53.56	1.00e-165	577.00
IUUC-Tre-121884	Trichoderma reesei	32.28	4.00e-12	67.00
IUUC-Tvi-122552	Trichoderma virens	31.65	1.00e-12	68.60
IUUC-Tbe-127523	Tupaia belangeri	88.97	0.00e+00	961.00
IUUC-Ttr-128954	Tursiops truncatus	89.33	0.00e+00	952.00
IUUC-Vpa-130441	Vicugna pacos	89.87	0.00e+00	963.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence