iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-044857

UUCD1 version

UUC-GoG-00341

Ensembl Protein ID

ENSGGOP00000008137.3

UniProt Accession

G3QZ38; G3QZ38_GORGO

Protein Name

Uncharacterized protein

Gene Name

BIRC2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000008327.3	ENSGGOT00000008363.3	ENSGGOP00000008137.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	29.42	7.00e-63	238.00	IUUC-Dme-031819
E3 activity/RING/RING	99.68	0.00e+00	1176.00	IUUC-Hsa-045769

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MHKTASQRLF PGPSYQNIKS IMEDSTILSD WTNSNKQKMK YDFSCELYRM STYSTFPAGV 60
PVSERSLARA GFYYTGVNDK VKCFCCGLML DNWKLGDSPI QKHKQLYPSC SFIQNLVSAS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGATGGGGCG GCGGGCTTCG GGAGCGCCCG GGCTGATCCG AGCCGAGCGG GCCGTATCTC 60
CTTGGCGCAG CTGATTCCCG GCTCTGAGGA GGCCTCTAGG CAGCCGCGCA GCTTCCGTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR028795--C-IAP1
IPR001315--CARD
IPR011029--DEATH-like_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01282--BIR_REPEAT_1
PS50143--BIR_REPEAT_2
PS50209--CARD
PS50089--ZF_RING_2

Pfam

PF00653--BIR
PF00619--CARD

SMART

SM00238--BIR
SM00114--CARD
SM00184--RING

Gene Ontology

GO:0035631--C:CD40 receptor complex
GO:0005737--C:cytoplasm
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0005634--C:nucleus
GO:0003713--F:transcription coactivator activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0071356--P:cellular response to tumor necrosis factor
GO:0070266--P:necroptotic process
GO:0043066--P:negative regulation of apoptotic process
GO:1902443--P:negative regulation of ripoptosome assembly involved in necroptotic process
GO:0001890--P:placenta development
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:1902524--P:positive regulation of protein K48-linked ubiquitination
GO:1902523--P:positive regulation of protein K63-linked ubiquitination
GO:1902527--P:positive regulation of protein monoubiquitination
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0051726--P:regulation of cell cycle
GO:0045595--P:regulation of cell differentiation
GO:0050727--P:regulation of inflammatory response
GO:1901222--P:regulation of NIK/NF-kappaB signaling
GO:2000377--P:regulation of reactive oxygen species metabolic process
GO:0034121--P:regulation of toll-like receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002369	Ailuropoda melanoleuca	87.92	0.00e+00	1075.00
IUUC-Aca-004515	Anolis carolinensis	69.44	0.00e+00	773.00
IUUC-Aly-006460	Arabidopsis lyrata	38.89	1.00e-09	56.60
IUUC-Afl-008648	Aspergillus flavus	31.03	1.00e-14	75.50
IUUC-Ame-011877	Astyanax mexicanus	55.17	0.00e+00	655.00
IUUC-Bgr-012051	Blumeria graminis	33.76	2.00e-12	67.80
IUUC-Bta-012450	Bos taurus	88.25	0.00e+00	957.00
IUUC-Bci-013905	Botrytis cinerea	35.00	1.00e-16	81.60
IUUC-Cja-018895	Callithrix jacchus	95.48	0.00e+00	1127.00
IUUC-Cfa-020419	Canis familiaris	87.88	0.00e+00	1076.00
IUUC-Cpo-022048	Cavia porcellus	88.35	0.00e+00	1070.00
IUUC-Cho-024277	Choloepus hoffmanni	86.43	0.00e+00	1026.00
IUUC-Cin-025521	Ciona intestinalis	30.85	4.00e-76	279.00
IUUC-Dre-028647	Danio rerio	54.95	0.00e+00	642.00
IUUC-Dno-029509	Dasypus novemcinctus	82.23	0.00e+00	956.00
IUUC-Dor-030796	Dipodomys ordii	74.48	6.00e-99	354.00
IUUC-Dme-031819	Drosophila melanogaster	29.13	1.00e-66	247.00
IUUC-Ete-032768	Echinops telfairi	69.01	0.00e+00	729.00
IUUC-Eca-033393	Equus caballus	92.82	0.00e+00	1085.00
IUUC-Eeu-035114	Erinaceus europaeus	85.44	0.00e+00	1017.00
IUUC-Fca-036034	Felis catus	87.08	0.00e+00	1046.00
IUUC-Gmo-038477	Gadus morhua	55.57	4.00e-178	617.00
IUUC-Gga-040601	Gallus gallus	71.48	0.00e+00	844.00
IUUC-Gac-041467	Gasterosteus aculeatus	56.68	0.00e+00	629.00
IUUC-Hsa-045769	Homo sapiens	99.68	0.00e+00	1176.00
IUUC-Itr-048441	Ictidomys tridecemlineatus	91.21	0.00e+00	1095.00
IUUC-Lch-050259	Latimeria chalumnae	61.14	0.00e+00	722.00
IUUC-Loc-052169	Lepisosteus oculatus	54.63	7.00e-172	597.00
IUUC-Laf-053449	Loxodonta africana	86.43	0.00e+00	1042.00
IUUC-Meu-056241	Macropus eugenii	69.60	0.00e+00	708.00
IUUC-Mga-059947	Meleagris gallopavo	71.50	0.00e+00	848.00
IUUC-Mdo-062352	Monodelphis domestica	77.53	0.00e+00	928.00
IUUC-Mmu-064340	Mus musculus	82.90	0.00e+00	1003.00
IUUC-Mpu-065890	Mustela putorius furo	88.25	0.00e+00	976.00
IUUC-Mlu-068077	Myotis lucifugus	90.22	0.00e+00	1077.00
IUUC-Nle-070081	Nomascus leucogenys	97.25	0.00e+00	1165.00
IUUC-Opr-070561	Ochotona princeps	83.82	0.00e+00	990.00
IUUC-Ont-071776	Oreochromis niloticus	54.69	0.00e+00	642.00
IUUC-Oan-073604	Ornithorhynchus anatinus	76.73	0.00e+00	895.00
IUUC-Ocu-073963	Oryctolagus cuniculus	90.79	0.00e+00	1057.00
IUUC-Ogu-078452	Oryza glumaepatula	47.73	3.00e-07	49.70
IUUC-Ome-081435	Oryza meridionalis	45.65	1.00e-06	47.40
IUUC-Oni-082044	Oryza nivara	43.64	2.00e-09	57.40
IUUC-Opu-084085	Oryza punctata	41.67	1.00e-06	47.00
IUUC-Oru-085060	Oryza rufipogon	46.51	9.00e-07	48.10
IUUC-Ola-086446	Oryzias latipes	52.56	8.00e-174	603.00
IUUC-Oga-087976	Otolemur garnettii	92.56	0.00e+00	1106.00
IUUC-Oar-090097	Ovis aries	88.30	0.00e+00	1081.00
IUUC-Ptr-091137	Pan troglodytes	99.51	0.00e+00	1175.00
IUUC-Pan-092673	Papio anubis	98.22	0.00e+00	1170.00
IUUC-Psi-092992	Pelodiscus sinensis	71.15	0.00e+00	835.00
IUUC-Pma-094277	Petromyzon marinus	37.63	5.00e-112	398.00
IUUC-Pfo-096790	Poecilia formosa	53.80	3.00e-178	618.00
IUUC-Pab-098734	Pongo abelii	99.33	0.00e+00	1131.00
IUUC-Pop-098944	Populus trichocarpa	42.59	5.00e-10	58.20
IUUC-Pca-100708	Procavia capensis	73.36	1.00e-177	615.00
IUUC-Pva-102788	Pteropus vampyrus	91.76	0.00e+00	1095.00
IUUC-Rno-105026	Rattus norvegicus	81.24	0.00e+00	964.00
IUUC-Sha-107229	Sarcophilus harrisii	71.61	0.00e+00	851.00
IUUC-Sja-107720	Schizosaccharomyces japonicus	33.56	1.00e-15	79.00
IUUC-Ssc-115804	Sus scrofa	87.78	0.00e+00	1045.00
IUUC-Tru-117620	Takifugu rubripes	53.54	0.00e+00	627.00
IUUC-Tni-119683	Tetraodon nigroviridis	54.12	2.00e-180	625.00
IUUC-Tbe-127523	Tupaia belangeri	91.75	0.00e+00	1115.00
IUUC-Ttr-128954	Tursiops truncatus	88.06	0.00e+00	1056.00
IUUC-Vpa-130441	Vicugna pacos	89.97	0.00e+00	1083.00
IUUC-Xtr-132031	Xenopus tropicalis	58.12	0.00e+00	655.00
IUUC-Xma-132984	Xiphophorus maculatus	54.77	1.00e-180	626.00
IUUC-Yli-134629	Yarrowia lipolytica	32.79	5.00e-16	79.70

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence