iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048441

Ensembl Protein ID

ENSSTOP00000005140.2

UniProt Accession

I3M6M0; I3M6M0_ICTTR

Genbank Protein ID

ENSSTOP00000005140

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01056125

Gene Name

BIRC2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000005754.2	ENSSTOT00000005748.2	ENSSTOP00000005140.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	91.53	0.00e+00	1098.00	IUUC-Hsa-045769

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

QNYLQRVIQD PLHQKIRSIM EDSTILSNWT NNNKQTMKYD FSCELYRMST YSTFPIGVPV 60
SERSLARAGF YYTGVNDKVR CFCCGLMLDN WKQGDSPIEK HKQLYPSCSF IQNLVSSSLQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAAAACTACC TCCAAAGAGT TATCCAAGAT CCCTTGCATC AAAAAATAAG GAGTATAATG 60
GAAGACAGCA CAATCTTGTC AAATTGGACA AATAACAACA AACAAACAAT GAAGTATGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR028795--C-IAP1
IPR001315--CARD
IPR011029--DEATH-like_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01282--BIR_REPEAT_1
PS50143--BIR_REPEAT_2
PS50209--CARD
PS50089--ZF_RING_2

Pfam

PF00653--BIR
PF00619--CARD

SMART

SM00238--BIR
SM00114--CARD
SM00184--RING

Gene Ontology

GO:0035631--C:CD40 receptor complex
GO:0005737--C:cytoplasm
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0005634--C:nucleus
GO:0003713--F:transcription coactivator activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0071356--P:cellular response to tumor necrosis factor
GO:0070266--P:necroptotic process
GO:0043066--P:negative regulation of apoptotic process
GO:1902443--P:negative regulation of ripoptosome assembly involved in necroptotic process
GO:0001890--P:placenta development
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:1902524--P:positive regulation of protein K48-linked ubiquitination
GO:1902523--P:positive regulation of protein K63-linked ubiquitination
GO:1902527--P:positive regulation of protein monoubiquitination
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0051726--P:regulation of cell cycle
GO:0045595--P:regulation of cell differentiation
GO:0050727--P:regulation of inflammatory response
GO:1901222--P:regulation of NIK/NF-kappaB signaling
GO:2000377--P:regulation of reactive oxygen species metabolic process
GO:0034121--P:regulation of toll-like receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002369	Ailuropoda melanoleuca	86.55	0.00e+00	1056.00
IUUC-Aly-006460	Arabidopsis lyrata	37.04	2.00e-09	55.80
IUUC-Acl-008330	Aspergillus clavatus	29.55	4.00e-14	73.60
IUUC-Afl-008648	Aspergillus flavus	31.03	8.00e-15	75.90
IUUC-Afu-008813	Aspergillus fumigatus	30.36	1.00e-13	72.00
IUUC-Ang-009667	Aspergillus niger	30.25	1.00e-12	68.60
IUUC-Ame-011877	Astyanax mexicanus	55.31	0.00e+00	650.00
IUUC-Bta-012450	Bos taurus	88.27	0.00e+00	964.00
IUUC-Bol-015478	Brassica oleracea	31.36	7.00e-10	61.60
IUUC-Bra-017001	Brassica rapa	32.20	4.00e-10	62.80
IUUC-Cja-018895	Callithrix jacchus	90.24	0.00e+00	1066.00
IUUC-Cfa-020419	Canis familiaris	86.82	0.00e+00	1048.00
IUUC-Cpo-022048	Cavia porcellus	88.60	0.00e+00	1063.00
IUUC-Cho-024277	Choloepus hoffmanni	84.42	0.00e+00	999.00
IUUC-Cin-025521	Ciona intestinalis	30.35	3.00e-73	269.00
IUUC-Dor-030796	Dipodomys ordii	73.26	2.00e-95	343.00
IUUC-Eca-033393	Equus caballus	92.01	0.00e+00	1075.00
IUUC-Eeu-035114	Erinaceus europaeus	85.50	0.00e+00	994.00
IUUC-Fca-036034	Felis catus	85.37	0.00e+00	1025.00
IUUC-Fox-037889	Fusarium oxysporum	31.03	3.00e-15	77.00
IUUC-Ggo-044857	Gorilla gorilla	91.21	0.00e+00	1080.00
IUUC-Hsa-045769	Homo sapiens	91.53	0.00e+00	1083.00
IUUC-Laf-053449	Loxodonta africana	86.25	0.00e+00	1023.00
IUUC-Mor-057252	Magnaporthe oryzae	33.96	3.00e-17	84.00
IUUC-Mdo-062352	Monodelphis domestica	78.15	0.00e+00	920.00
IUUC-Mmu-064340	Mus musculus	84.58	0.00e+00	1017.00
IUUC-Mpu-065890	Mustela putorius furo	86.71	0.00e+00	972.00
IUUC-Mlu-068077	Myotis lucifugus	88.05	0.00e+00	1088.00
IUUC-Nfi-068591	Neosartorya fischeri	30.23	1.00e-13	72.00
IUUC-Nle-070081	Nomascus leucogenys	89.58	0.00e+00	1083.00
IUUC-Opr-070561	Ochotona princeps	85.76	0.00e+00	988.00
IUUC-Ocu-073963	Oryctolagus cuniculus	89.82	0.00e+00	1050.00
IUUC-Ogu-078452	Oryza glumaepatula	45.45	4.00e-07	48.90
IUUC-Oni-082044	Oryza nivara	41.82	2.00e-09	57.00
IUUC-Oru-085060	Oryza rufipogon	44.19	1.00e-06	47.80
IUUC-Oga-087976	Otolemur garnettii	90.39	0.00e+00	1081.00
IUUC-Oar-090097	Ovis aries	86.89	0.00e+00	1075.00
IUUC-Ptr-091137	Pan troglodytes	91.37	0.00e+00	1082.00
IUUC-Pan-092673	Papio anubis	92.02	0.00e+00	1094.00
IUUC-Pfo-096790	Poecilia formosa	54.03	5.00e-177	613.00
IUUC-Pab-098734	Pongo abelii	92.99	0.00e+00	1072.00
IUUC-Pop-098944	Populus trichocarpa	42.59	5.00e-10	58.20
IUUC-Pca-100708	Procavia capensis	72.17	9.00e-173	599.00
IUUC-Pva-102788	Pteropus vampyrus	89.76	0.00e+00	1064.00
IUUC-Rno-105026	Rattus norvegicus	83.31	0.00e+00	984.00
IUUC-Sja-107720	Schizosaccharomyces japonicus	32.89	1.00e-15	79.00
IUUC-Ssc-115804	Sus scrofa	86.31	0.00e+00	1040.00
IUUC-Tru-117620	Takifugu rubripes	55.85	0.00e+00	628.00
IUUC-Tbe-127523	Tupaia belangeri	89.25	0.00e+00	1085.00
IUUC-Ttr-128954	Tursiops truncatus	86.36	0.00e+00	1034.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence