iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000011526.3	ENSMMUT00000016141.3	ENSMMUP00000015128.3
ENSMMUG00000011526.3	ENSMMUT00000016142.3	ENSMMUP00000015129.3
ENSMMUG00000011526.3	ENSMMUT00000054053.1	ENSMMUP00000060638.1
ENSMMUG00000011526.3	ENSMMUT00000016143.3	ENSMMUP00000015130.3
ENSMMUG00000011526.3	ENSMMUT00000070445.1	ENSMMUP00000047819.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-07	32.6	93	126

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd..tllvsGsdDgtikvWDlr 31
           gH    +c+ f ++  +l++sG+ Dg +++WDl+
   Q: 93   GHRRTPWCVTFhPTisGLIASGCLDGEVRIWDLH 126
           6777779*****76779***************97 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MKVVPEKNAV RILWGRERGA RAMGAQRLLQ ELVEDKTRWM KWEGKRVELP DSPRSTFLLA 60
FSPDRTLLAS THVNHNIYIT EVKTGKCVHS LIGHRRTPWC VTFHPTISGL IASGCLDGEV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTTGCACAG GCTGGTCTTG AACTCCTGGG CTCAAAGCAA TCCACCAGCC TGGTCTCCTA 60
AAGTGCTCGA ATTATGGACG AGAGCCGCTG CGTCCGACCA AACTGGGACT ATCTTGTTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

SMART

SM00320--WD40

Gene Ontology

GO:0005930--C:axoneme
GO:0005829--C:cytosol
GO:0005739--C:mitochondrion
GO:0045335--C:phagocytic vesicle
GO:0006914--P:autophagy
GO:0008285--P:negative regulation of cell proliferation
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0021915--P:neural tube development
GO:0098779--P:positive regulation of macromitophagy in response to mitochondrial depolarization
GO:0043552--P:positive regulation of phosphatidylinositol 3-kinase activity
GO:2000785--P:regulation of autophagosome assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001917	Ailuropoda melanoleuca	94.42	0.00e+00	1769.00
IUUC-Atr-002557	Amborella trichopoda	37.74	3.00e-30	127.00
IUUC-Apl-004186	Anas platyrhynchos	79.38	0.00e+00	1901.00
IUUC-Aca-004419	Anolis carolinensis	75.34	0.00e+00	1797.00
IUUC-Aly-006308	Arabidopsis lyrata	37.85	9.00e-29	122.00
IUUC-Ath-007656	Arabidopsis thaliana	37.09	3.00e-28	120.00
IUUC-Ame-011354	Astyanax mexicanus	57.25	0.00e+00	1270.00
IUUC-Bta-012455	Bos taurus	92.43	0.00e+00	2195.00
IUUC-Bdi-014580	Brachypodium distachyon	42.33	4.00e-30	127.00
IUUC-Bol-016094	Brassica oleracea	40.22	8.00e-29	122.00
IUUC-Bra-017308	Brassica rapa	40.76	8.00e-30	125.00
IUUC-Cja-019073	Callithrix jacchus	98.82	7.00e-170	590.00
IUUC-Cfa-020994	Canis familiaris	90.43	0.00e+00	1489.00
IUUC-Cpo-022101	Cavia porcellus	92.38	0.00e+00	2169.00
IUUC-Csa-023273	Chlorocebus sabaeus	95.92	0.00e+00	1609.00
IUUC-Cin-025567	Ciona intestinalis	54.64	7.00e-56	211.00
IUUC-Csv-026005	Ciona savignyi	51.26	6.00e-56	210.00
IUUC-Dre-028282	Danio rerio	56.96	0.00e+00	1260.00
IUUC-Dno-029948	Dasypus novemcinctus	93.46	0.00e+00	2192.00
IUUC-Dor-030568	Dipodomys ordii	97.21	0.00e+00	1249.00
IUUC-Ete-032864	Echinops telfairi	86.13	0.00e+00	1869.00
IUUC-Eca-034392	Equus caballus	93.22	0.00e+00	1603.00
IUUC-Eeu-034440	Erinaceus europaeus	97.50	0.00e+00	1198.00
IUUC-Fca-035359	Felis catus	91.72	0.00e+00	2146.00
IUUC-Fal-037483	Ficedula albicollis	79.40	0.00e+00	1938.00
IUUC-Gmo-039343	Gadus morhua	71.01	0.00e+00	738.00
IUUC-Gga-040787	Gallus gallus	78.46	0.00e+00	1201.00
IUUC-Gac-041321	Gasterosteus aculeatus	60.08	0.00e+00	1331.00
IUUC-Gma-044022	Glycine max	36.63	3.00e-29	124.00
IUUC-Ggo-044775	Gorilla gorilla	98.10	0.00e+00	1053.00
IUUC-Hsa-045708	Homo sapiens	96.38	0.00e+00	2273.00
IUUC-Hvu-047536	Hordeum vulgare	41.57	1.00e-29	125.00
IUUC-Itr-048376	Ictidomys tridecemlineatus	98.27	0.00e+00	1269.00
IUUC-Lch-050255	Latimeria chalumnae	68.31	0.00e+00	1393.00
IUUC-Lpe-050684	Leersia perrieri	41.76	1.00e-30	128.00
IUUC-Loc-052881	Lepisosteus oculatus	65.76	0.00e+00	1465.00
IUUC-Laf-053342	Loxodonta africana	69.28	0.00e+00	944.00
IUUC-Meu-056320	Macropus eugenii	84.59	0.00e+00	1074.00
IUUC-Mtr-058484	Medicago truncatula	38.54	2.00e-29	124.00
IUUC-Mga-059401	Meleagris gallopavo	82.38	0.00e+00	1637.00
IUUC-Mmr-061037	Microcebus murinus	93.86	0.00e+00	2181.00
IUUC-Mdo-062484	Monodelphis domestica	79.97	0.00e+00	1004.00
IUUC-Mmu-064090	Mus musculus	93.08	0.00e+00	2189.00
IUUC-Mac-065675	Musa acuminata	34.89	2.00e-29	124.00
IUUC-Mpu-066165	Mustela putorius furo	92.32	0.00e+00	1503.00
IUUC-Mlu-068038	Myotis lucifugus	92.77	0.00e+00	2240.00
IUUC-Nle-069361	Nomascus leucogenys	96.12	0.00e+00	1935.00
IUUC-Opr-070360	Ochotona princeps	94.03	0.00e+00	886.00
IUUC-Ont-071277	Oreochromis niloticus	61.53	0.00e+00	1334.00
IUUC-Oan-073623	Ornithorhynchus anatinus	87.07	0.00e+00	1053.00
IUUC-Ocu-074600	Oryctolagus cuniculus	93.56	0.00e+00	1378.00
IUUC-Oba-075024	Oryza barthii	38.19	4.00e-32	133.00
IUUC-Obr-076172	Oryza brachyantha	34.71	8.00e-33	135.00
IUUC-Ogl-077411	Oryza glaberrima	34.30	6.00e-32	132.00
IUUC-Ogu-078025	Oryza glumaepatula	38.19	6.00e-32	133.00
IUUC-Oni-082463	Oryza nivara	38.19	5.00e-32	133.00
IUUC-Opu-084041	Oryza punctata	38.19	9.00e-32	132.00
IUUC-Oru-085075	Oryza rufipogon	38.19	2.00e-31	131.00
IUUC-Osa-085781	Oryza sativa	38.19	6.00e-32	132.00
IUUC-Ola-086729	Oryzias latipes	61.57	0.00e+00	1359.00
IUUC-Olu-087735	Ostreococcus lucimarinus	40.32	7.00e-24	105.00
IUUC-Oga-089113	Otolemur garnettii	93.23	0.00e+00	2104.00
IUUC-Oar-090171	Ovis aries	93.19	0.00e+00	2043.00
IUUC-Ptr-090970	Pan troglodytes	96.46	0.00e+00	2275.00
IUUC-Pan-092778	Papio anubis	95.92	0.00e+00	1636.00
IUUC-Psi-093571	Pelodiscus sinensis	79.38	0.00e+00	1932.00
IUUC-Pma-094563	Petromyzon marinus	74.58	2.00e-106	378.00
IUUC-Ppa-095832	Physcomitrella patens	36.70	1.00e-30	128.00
IUUC-Pfo-097365	Poecilia formosa	59.05	0.00e+00	1241.00
IUUC-Pab-098647	Pongo abelii	98.97	0.00e+00	1245.00
IUUC-Pop-099742	Populus trichocarpa	40.32	1.00e-29	125.00
IUUC-Pca-101035	Procavia capensis	92.35	0.00e+00	1166.00
IUUC-Ppe-101783	Prunus persica	42.22	2.00e-29	124.00
IUUC-Pva-103187	Pteropus vampyrus	99.01	0.00e+00	942.00
IUUC-Rno-105701	Rattus norvegicus	93.08	0.00e+00	2174.00
IUUC-Sha-107612	Sarcophilus harrisii	83.19	0.00e+00	1963.00
IUUC-Smo-109107	Selaginella moellendorffii	39.66	5.00e-27	116.00
IUUC-Sit-110786	Setaria italica	38.12	2.00e-32	134.00
IUUC-Sly-110859	Solanum lycopersicum	38.10	6.00e-32	132.00
IUUC-Stu-112031	Solanum tuberosum	38.57	5.00e-32	133.00
IUUC-Sar-113242	Sorex araneus	96.03	0.00e+00	1092.00
IUUC-Ssc-116094	Sus scrofa	94.31	0.00e+00	2229.00
IUUC-Tru-118308	Takifugu rubripes	60.62	0.00e+00	1294.00
IUUC-Tsy-119552	Tarsius syrichta	94.71	0.00e+00	1218.00
IUUC-Tca-121616	Theobroma cacao	38.10	1.00e-30	128.00
IUUC-Tae-124768	Triticum aestivum	42.17	4.00e-30	126.00
IUUC-Tur-126480	Triticum urartu	42.17	2.00e-30	127.00
IUUC-Tbe-127902	Tupaia belangeri	95.47	0.00e+00	981.00
IUUC-Ttr-129278	Tursiops truncatus	94.55	0.00e+00	1180.00
IUUC-Vpa-130741	Vicugna pacos	90.37	0.00e+00	848.00
IUUC-Vvi-131437	Vitis vinifera	40.30	2.00e-29	124.00
IUUC-Xtr-132247	Xenopus tropicalis	64.38	0.00e+00	1308.00
IUUC-Xma-134277	Xiphophorus maculatus	59.65	0.00e+00	1356.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence