iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-060035

Ensembl Protein ID

ENSMGAP00000008321.2

UniProt Accession

G1N7V8; G1N7V8_MELGA

Protein Name

Small ubiquitin-related modifier

Gene Name

SUMO1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000008144.2	ENSMGAT00000009115.2	ENSMGAP00000008321.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UBL/SUMO	3.20e-31	107.7	17	94
ULD/UDP/UBQ/UBQ_Other	5.00e-07	29.3	25	92

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UBL/SUMO

   S: 7    apvslkvagqdGsevlfklklsaqlkklmeavYvkrinldensvrfvfngqkireqetpeelevededkiellcqksGG 85
           ++++lkv gqd+se++fk+k++++lkkl+e+ Y++r+++ +ns+rf+f+gq+i +++tp+el++e+ed+ie++++++GG
   Q: 17   EYIKLKVIGQDSSEIHFKVKMTTHLKKLKES-YCQRQGVPMNSLRFLFEGQRITDNHTPKELGMEEEDVIEVYQEQTGG 94
           69*****************************.**********************************************9 PP

ULD/UDP/UBQ/UBQ_Other

   S: 7    sldgseltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllekks 74
             d+se  +kv+ ++  ++LKe   +++g+p+++ r +++G+ + d++t +++g+ ++++i +++++ 
   Q: 25   GQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMNSLRFLFEGQRITDNHTPKELGMEEEDVIEVYQEQT 92
           445557778899999*************************************************9875 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

QEAKPSAEDL GDKKEGEYIK LKVIGQDSSE IHFKVKMTTH LKKLKESYCQ RQGVPMNSLR 60
FLFEGQRITD NHTPKELGME EEDVIEVYQE QTGGHSTV 98

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGAAGCAA AGCCTTCAGC TGAGGACTTA GGAGATAAGA AAGAGGGGGA ATACATTAAA 60
CTCAAAGTCA TTGGGCAGGT GAGTTTTTAC ATAATGGATA TCTGGGAGAT GGTGTGAATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR022617--Rad60/SUMO-like_dom
IPR033950--Sumo
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50053--UBIQUITIN_2

Pfam

PF11976--Rad60-SLD

SMART

SM00213--UBQ

Gene Ontology

GO:0031965--C:nuclear membrane
GO:0097165--C:nuclear stress granule
GO:0005730--C:nucleolus
GO:0016605--C:PML body
GO:0008076--C:voltage-gated potassium channel complex
GO:0015459--F:potassium channel regulator activity
GO:0003723--F:RNA binding
GO:0008134--F:transcription factor binding
GO:0071276--P:cellular response to cadmium ion
GO:0034605--P:cellular response to heat
GO:0045759--P:negative regulation of action potential
GO:1902260--P:negative regulation of delayed rectifier potassium channel activity
GO:0043392--P:negative regulation of DNA binding
GO:0043433--P:negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0060021--P:palate development
GO:0030578--P:PML body organization
GO:1901896--P:positive regulation of calcium-transporting ATPase activity
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0031334--P:positive regulation of protein complex assembly
GO:0090204--P:protein localization to nuclear pore
GO:0050821--P:protein stabilization
GO:0016925--P:protein sumoylation
GO:0086004--P:regulation of cardiac muscle cell contraction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001056	Aegilops tauschii	48.61	7.00e-17	78.60
IUUC-Aml-001606	Ailuropoda melanoleuca	96.94	4.00e-53	198.00
IUUC-Apl-003638	Anas platyrhynchos	100.00	3.00e-54	202.00
IUUC-Aca-004710	Anolis carolinensis	96.91	2.00e-52	196.00
IUUC-Ago-007749	Ashbya gossypii	51.95	2.00e-18	82.80
IUUC-Ani-009300	Aspergillus nidulans	41.30	1.00e-16	77.00
IUUC-Ame-011662	Astyanax mexicanus	87.23	4.00e-44	168.00
IUUC-Bta-013491	Bos taurus	97.96	2.00e-53	199.00
IUUC-Cel-018251	Caenorhabditis elegans	65.82	7.00e-29	117.00
IUUC-Cja-019109	Callithrix jacchus	97.96	2.00e-53	199.00
IUUC-Cfa-020657	Canis familiaris	96.94	3.00e-53	198.00
IUUC-Cpo-022508	Cavia porcellus	97.94	9.00e-53	196.00
IUUC-Cre-022970	Chlamydomonas reinhardtii	48.24	1.00e-19	87.00
IUUC-Csa-023026	Chlorocebus sabaeus	96.94	4.00e-43	164.00
IUUC-Cho-024767	Choloepus hoffmanni	98.61	1.00e-38	150.00
IUUC-Cne-027072	Cryptococcus neoformans	48.48	1.00e-14	70.50
IUUC-Dre-028383	Danio rerio	88.17	5.00e-43	164.00
IUUC-Dno-029820	Dasypus novemcinctus	97.96	2.00e-53	199.00
IUUC-Ete-032782	Echinops telfairi	74.23	2.00e-34	136.00
IUUC-Eca-033958	Equus caballus	96.94	3.00e-53	198.00
IUUC-Eeu-034822	Erinaceus europaeus	97.92	2.00e-52	195.00
IUUC-Fca-035601	Felis catus	96.94	4.00e-53	198.00
IUUC-Fal-036740	Ficedula albicollis	100.00	4.00e-54	202.00
IUUC-Gmo-038847	Gadus morhua	92.65	9.00e-34	133.00
IUUC-Gga-040129	Gallus gallus	100.00	2.00e-54	202.00
IUUC-Gac-042112	Gasterosteus aculeatus	87.10	1.00e-44	169.00
IUUC-Ggo-045413	Gorilla gorilla	97.96	2.00e-53	199.00
IUUC-Hsa-046108	Homo sapiens	97.96	2.00e-53	199.00
IUUC-Itr-047968	Ictidomys tridecemlineatus	97.94	8.00e-53	197.00
IUUC-Lch-049881	Latimeria chalumnae	82.98	7.00e-37	144.00
IUUC-Loc-052189	Lepisosteus oculatus	90.43	2.00e-47	179.00
IUUC-Laf-053478	Loxodonta africana	96.94	1.00e-52	197.00
IUUC-Mcc-055059	Macaca mulatta	64.19	4.00e-46	176.00
IUUC-Meu-056112	Macropus eugenii	96.94	1.00e-52	197.00
IUUC-Mla-059030	Melampsora laricipopulina	40.51	1.00e-07	48.10
IUUC-Mmr-060903	Microcebus murinus	97.96	2.00e-53	199.00
IUUC-Mdo-062633	Monodelphis domestica	96.94	6.00e-53	197.00
IUUC-Mmu-063272	Mus musculus	97.96	2.00e-53	199.00
IUUC-Mpu-066505	Mustela putorius furo	95.92	2.00e-52	196.00
IUUC-Mlu-067469	Myotis lucifugus	97.96	3.00e-53	198.00
IUUC-Nle-069344	Nomascus leucogenys	98.63	2.00e-39	152.00
IUUC-Opr-070351	Ochotona princeps	46.94	1.00e-15	75.10
IUUC-Ont-071436	Oreochromis niloticus	87.10	1.00e-44	169.00
IUUC-Oan-072986	Ornithorhynchus anatinus	100.00	5.00e-26	107.00
IUUC-Ocu-073781	Oryctolagus cuniculus	94.90	4.00e-51	191.00
IUUC-Ola-086373	Oryzias latipes	86.02	6.00e-43	164.00
IUUC-Olu-087670	Ostreococcus lucimarinus	44.29	9.00e-17	77.40
IUUC-Oga-088024	Otolemur garnettii	86.73	2.00e-47	179.00
IUUC-Oar-089991	Ovis aries	97.96	3.00e-53	198.00
IUUC-Ptr-090688	Pan troglodytes	95.92	4.00e-52	194.00
IUUC-Pan-092204	Papio anubis	97.96	2.00e-53	199.00
IUUC-Psi-093396	Pelodiscus sinensis	100.00	3.00e-54	202.00
IUUC-Pfo-096306	Poecilia formosa	85.42	4.00e-44	169.00
IUUC-Pab-098393	Pongo abelii	97.96	3.00e-53	201.00
IUUC-Pca-100237	Procavia capensis	96.94	4.00e-51	192.00
IUUC-Pva-102353	Pteropus vampyrus	97.37	2.00e-40	156.00
IUUC-Pgr-103683	Puccinia graminis	40.74	3.00e-15	72.80
IUUC-Rno-105286	Rattus norvegicus	97.96	2.00e-53	199.00
IUUC-Sce-106231	Saccharomyces cerevisiae	47.92	3.00e-19	85.50
IUUC-Sha-106712	Sarcophilus harrisii	97.22	2.00e-38	149.00
IUUC-Sja-107710	Schizosaccharomyces japonicus	51.04	2.00e-22	96.70
IUUC-Spo-108261	Schizosaccharomyces pombe	51.06	1.00e-21	94.00
IUUC-Sit-110664	Setaria italica	32.58	4.00e-08	49.70
IUUC-Sar-113550	Sorex araneus	96.91	5.00e-52	194.00
IUUC-Sre-115172	Sporisorium reilianum	53.16	9.00e-20	87.40
IUUC-Ssc-115837	Sus scrofa	93.88	7.00e-52	194.00
IUUC-Tgu-117064	Taeniopygia guttata	100.00	8.00e-54	200.00
IUUC-Tru-117752	Takifugu rubripes	87.10	9.00e-45	170.00
IUUC-Tsy-119358	Tarsius syrichta	97.33	2.00e-39	153.00
IUUC-Tni-120621	Tetraodon nigroviridis	87.10	3.00e-44	168.00
IUUC-Tme-126902	Tuber melanosporum	45.68	8.00e-18	80.90
IUUC-Tbe-127355	Tupaia belangeri	74.23	2.00e-34	136.00
IUUC-Ttr-128166	Tursiops truncatus	95.92	4.00e-52	196.00
IUUC-Uma-129444	Ustilago maydis	53.16	3.00e-20	89.00
IUUC-Vpa-130172	Vicugna pacos	97.96	3.00e-53	199.00
IUUC-Xtr-132473	Xenopus tropicalis	92.93	5.00e-50	187.00
IUUC-Xma-133814	Xiphophorus maculatus	85.42	1.00e-44	170.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence