iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sja-107732

Ensembl Protein ID

EEB07256

UniProt Accession

B6K275; B6K275_SCHJY

Genbank Protein ID

EEB07256.1

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

KE651166

Gene Name

SJAG_02341

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SJAG_02341	EEB07256	EEB07256

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	4.00e-70	234.8	2	298

Active Site

Position(s)	Description	Evidence
83	Nucleophile	{ECO:0000256\|PIRSR:PIRSR038120-1}
159	Proton donor	{ECO:0000256\|PIRSR:PIRSR038120-1}

Domain Profile

DUB/UCH

   S: 7    ewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqvigNsCatyAllsv 107
           +w +Lesd+g+ft+l+e++gvk++ qv+ely Ld e+l+++ + ++g+++lFk++++ ++++            d+  +++++f +q i+N+Cat+Al+s 
   Q: 2    SWSTLESDAGVFTDLIENLGVKDV-QVDELYCLDVETLQQF-QKIYGIIFLFKWKKQADNFD---------GELDYASLDELYFPQQIISNACATQALMSI 91
           7***********************.****************.89***************999.........6689************************** PP
   S: 108  llncedklldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvsyvningrlyeldglkpfPldlgkkke 208
           lln++++ +d+G++l ++ ++tk   ++ k++algn++ ++c+hns+ar +++ ++e + +++   +++++hf++y+ in++lyeldgl+p+P+ +gk +e
   Q: 92   LLNHTNE-IDIGNDLREFYDFTKELPADLKGEALGNSELIRCVHNSFARADPFISDESRPATD---DDDVYHFIAYTLINDKLYELDGLQPAPICHGK-CE 187
           *******.5***********************************************9997776...99*****************************9.67 PP
   S: 209  teelkdklkvvraflerikllesdeirfnllaivadrrviktlrlnvlkidkeLlkLlkdieseeekieaqlddekekrkkfkiddirRtenydeficifi 309
           +  + +++  v+    ri ++  +eirfnl+ +++drr i+++                d    + ++ a l+ e+ekr ++k +++ R++n+++ +++++
   Q: 188  KPLFASRVVPVI--QSRIAKYPPNEIRFNLMVLSPDRRRIIQQ----------------DPSLSDTEKTAILAVEEEKRARWKRENQLRKHNFVGMFLELL 270
           788888888888..8*********************9944433................334455667899****************************** PP
   S: 310  kdlaregilrklveetisevrefgvnegr 338
           k   +++i + +++et+ ++  +   +++
   Q: 271  KLSVKDQIDKGTWNETLQQRI-QSHTQNQ 298
           ****************95543.4444444 PP

Organism

Schizosaccharomyces japonicus

Protein Sequence
(Fasta)

MSWSTLESDA GVFTDLIENL GVKDVQVDEL YCLDVETLQQ FQKIYGIIFL FKWKKQADNF 60
DGELDYASLD ELYFPQQIIS NACATQALMS ILLNHTNEID IGNDLREFYD FTKELPADLK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCTTATTAA ACCTCTTTCA TCTCACATCC ATAGATTACT AAGCTACGAT AATAAAGCGT 60
ACCATACAGA ATCAATACCA ACGCAAAAAA TAAAACTTTA AGTTCTACGT CCATTCCCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR017390--Ubiquitinyl_hydrolase_UCH37

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0034399--C:nuclear periphery
GO:0031595--C:nuclear proteasome complex
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000936	Aegilops tauschii	43.53	5.00e-65	239.00
IUUC-Aml-001866	Ailuropoda melanoleuca	38.87	2.00e-59	220.00
IUUC-Atr-002966	Amborella trichopoda	41.51	2.00e-56	211.00
IUUC-Apl-003306	Anas platyrhynchos	35.19	9.00e-52	195.00
IUUC-Aca-004763	Anolis carolinensis	38.87	2.00e-59	220.00
IUUC-Aly-005581	Arabidopsis lyrata	40.66	4.00e-60	223.00
IUUC-Ath-007283	Arabidopsis thaliana	40.36	5.00e-62	229.00
IUUC-Ago-007999	Ashbya gossypii	34.81	3.00e-37	146.00
IUUC-Acl-008231	Aspergillus clavatus	44.97	2.00e-70	256.00
IUUC-Afl-008557	Aspergillus flavus	49.82	2.00e-74	270.00
IUUC-Afu-008988	Aspergillus fumigatus	44.97	2.00e-69	253.00
IUUC-Ani-009420	Aspergillus nidulans	47.02	6.00e-74	268.00
IUUC-Ang-009859	Aspergillus niger	44.51	2.00e-67	246.00
IUUC-Aor-010145	Aspergillus oryzae	49.82	2.00e-74	270.00
IUUC-Ate-010347	Aspergillus terreus	45.78	1.00e-72	264.00
IUUC-Ame-010791	Astyanax mexicanus	40.68	4.00e-59	219.00
IUUC-Bgr-012298	Blumeria graminis	49.20	7.00e-78	281.00
IUUC-Bta-013251	Bos taurus	39.33	5.00e-60	222.00
IUUC-Bci-013786	Botrytis cinerea	49.84	5.00e-84	301.00
IUUC-Bdi-014132	Brachypodium distachyon	48.47	2.00e-58	217.00
IUUC-Bol-015611	Brassica oleracea	41.39	3.00e-61	226.00
IUUC-Bra-017769	Brassica rapa	41.39	3.00e-61	226.00
IUUC-Cel-018604	Caenorhabditis elegans	37.11	2.00e-48	184.00
IUUC-Cja-019768	Callithrix jacchus	34.95	7.00e-54	202.00
IUUC-Cfa-020207	Canis familiaris	38.87	2.00e-59	220.00
IUUC-Cpo-021925	Cavia porcellus	36.88	7.00e-54	201.00
IUUC-Cre-022919	Chlamydomonas reinhardtii	38.64	3.00e-55	206.00
IUUC-Csa-023958	Chlorocebus sabaeus	39.00	1.00e-59	221.00
IUUC-Cho-024928	Choloepus hoffmanni	40.00	2.00e-13	67.80
IUUC-Cin-025771	Ciona intestinalis	35.69	6.00e-51	192.00
IUUC-Csv-026149	Ciona savignyi	35.35	9.00e-49	184.00
IUUC-Cgl-026424	Colletotrichum gloeosporioides	42.07	1.00e-64	237.00
IUUC-Cne-026955	Cryptococcus neoformans	35.33	7.00e-45	172.00
IUUC-Cme-027104	Cyanidioschyzon merolae	33.96	4.00e-41	159.00
IUUC-Dre-027409	Danio rerio	39.66	5.00e-58	215.00
IUUC-Dno-028921	Dasypus novemcinctus	38.87	3.00e-59	219.00
IUUC-Dor-030891	Dipodomys ordii	34.75	9.00e-29	120.00
IUUC-Dse-031170	Dothistroma septosporum	51.74	3.00e-84	303.00
IUUC-Dme-031677	Drosophila melanogaster	40.00	6.00e-52	195.00
IUUC-Ete-032646	Echinops telfairi	36.55	5.00e-28	117.00
IUUC-Eca-033776	Equus caballus	37.81	1.00e-52	197.00
IUUC-Eeu-035305	Erinaceus europaeus	37.22	1.00e-31	128.00
IUUC-Fca-035846	Felis catus	35.67	7.00e-55	205.00
IUUC-Fal-037597	Ficedula albicollis	37.81	3.00e-52	196.00
IUUC-Fox-037670	Fusarium oxysporum	50.00	1.00e-71	261.00
IUUC-Fso-038243	Fusarium solani	48.68	1.00e-71	261.00
IUUC-Gmo-038499	Gadus morhua	35.88	4.00e-50	189.00
IUUC-Ggr-039975	Gaeumannomyces graminis	45.64	2.00e-66	244.00
IUUC-Gga-040904	Gallus gallus	38.87	8.00e-60	221.00
IUUC-Gac-042058	Gasterosteus aculeatus	40.54	4.00e-59	219.00
IUUC-Gma-043763	Glycine max	42.68	3.00e-60	223.00
IUUC-Ggo-044699	Gorilla gorilla	43.61	1.00e-55	207.00
IUUC-Hsa-046227	Homo sapiens	38.87	9.00e-60	221.00
IUUC-Hvu-047359	Hordeum vulgare	42.90	1.00e-64	238.00
IUUC-Itr-048989	Ictidomys tridecemlineatus	34.94	5.00e-54	202.00
IUUC-Lch-049829	Latimeria chalumnae	40.20	3.00e-59	219.00
IUUC-Lpe-050899	Leersia perrieri	40.19	5.00e-59	219.00
IUUC-Loc-052264	Lepisosteus oculatus	39.86	9.00e-58	214.00
IUUC-Lma-053110	Leptosphaeria maculans	51.06	2.00e-73	267.00
IUUC-Laf-053639	Loxodonta africana	38.87	2.00e-59	220.00
IUUC-Mcc-055506	Macaca mulatta	39.00	1.00e-59	221.00
IUUC-Meu-056267	Macropus eugenii	36.82	8.00e-33	133.00
IUUC-Mor-057001	Magnaporthe oryzae	42.50	2.00e-66	243.00
IUUC-Mpo-057608	Magnaporthe poae	50.00	6.00e-46	174.00
IUUC-Mtr-057731	Medicago truncatula	42.50	3.00e-62	229.00
IUUC-Mla-059016	Melampsora laricipopulina	39.80	4.00e-39	152.00
IUUC-Mga-060178	Meleagris gallopavo	37.81	1.00e-52	197.00
IUUC-Mvi-060353	Microbotryum violaceum	40.57	5.00e-58	215.00
IUUC-Mmr-060738	Microcebus murinus	38.87	1.00e-59	221.00
IUUC-Mdo-062266	Monodelphis domestica	42.16	2.00e-47	179.00
IUUC-Mmu-063619	Mus musculus	39.20	3.00e-60	223.00
IUUC-Mac-065301	Musa acuminata	45.70	6.00e-66	242.00
IUUC-Mpu-066058	Mustela putorius furo	38.87	2.00e-59	220.00
IUUC-Mlu-067292	Myotis lucifugus	40.33	1.00e-60	224.00
IUUC-Nfi-068275	Neosartorya fischeri	45.60	3.00e-75	272.00
IUUC-Ncr-068713	Neurospora crassa	45.23	2.00e-76	276.00
IUUC-Nle-069013	Nomascus leucogenys	39.00	2.00e-59	220.00
IUUC-Opr-070628	Ochotona princeps	33.85	6.00e-49	186.00
IUUC-Ont-072688	Oreochromis niloticus	39.73	3.00e-57	213.00
IUUC-Oan-073004	Ornithorhynchus anatinus	42.58	1.00e-48	184.00
IUUC-Ocu-074303	Oryctolagus cuniculus	38.87	5.00e-59	219.00
IUUC-Oba-075002	Oryza barthii	40.48	6.00e-60	222.00
IUUC-Obr-076392	Oryza brachyantha	41.85	2.00e-59	220.00
IUUC-Ogl-077271	Oryza glaberrima	40.48	6.00e-60	222.00
IUUC-Ogu-078493	Oryza glumaepatula	40.48	1.00e-60	224.00
IUUC-Oin-080084	Oryza indica	40.48	1.00e-60	224.00
IUUC-Olo-080803	Oryza longistaminata	40.48	1.00e-60	224.00
IUUC-Ome-081146	Oryza meridionalis	40.72	1.00e-60	224.00
IUUC-Oni-082146	Oryza nivara	40.48	1.00e-60	224.00
IUUC-Opu-083633	Oryza punctata	42.17	2.00e-59	220.00
IUUC-Oru-084789	Oryza rufipogon	40.48	1.00e-60	224.00
IUUC-Osa-086196	Oryza sativa	40.48	1.00e-60	224.00
IUUC-Ola-087126	Oryzias latipes	40.00	4.00e-58	216.00
IUUC-Olu-087665	Ostreococcus lucimarinus	41.76	1.00e-60	224.00
IUUC-Oga-089140	Otolemur garnettii	35.37	2.00e-54	204.00
IUUC-Oar-090296	Ovis aries	39.26	1.00e-58	218.00
IUUC-Ptr-090566	Pan troglodytes	38.87	9.00e-60	221.00
IUUC-Pan-092052	Papio anubis	39.00	1.00e-59	221.00
IUUC-Psi-093723	Pelodiscus sinensis	37.81	2.00e-52	197.00
IUUC-Pma-094568	Petromyzon marinus	43.81	2.00e-46	176.00
IUUC-Pno-095120	Phaeosphaeria nodorum	50.70	9.00e-75	271.00
IUUC-Ppa-095761	Physcomitrella patens	40.12	1.00e-57	214.00
IUUC-Pfo-096210	Poecilia formosa	39.66	1.00e-58	218.00
IUUC-Pab-098463	Pongo abelii	38.87	1.00e-59	221.00
IUUC-Pop-099109	Populus trichocarpa	40.45	8.00e-59	218.00
IUUC-Pca-100108	Procavia capensis	42.36	3.00e-52	196.00
IUUC-Ppe-101176	Prunus persica	41.72	9.00e-58	214.00
IUUC-Pva-102629	Pteropus vampyrus	43.17	5.00e-54	202.00
IUUC-Pgr-103419	Puccinia graminis	40.00	1.00e-45	174.00
IUUC-Pte-104207	Pyrenophora teres	55.15	9.00e-46	173.00
IUUC-Pyt-104471	Pyrenophora triticirepentis	53.52	8.00e-83	298.00
IUUC-Rno-105579	Rattus norvegicus	33.44	9.00e-49	185.00
IUUC-Sha-106894	Sarcophilus harrisii	39.23	2.00e-48	183.00
IUUC-Spo-108371	Schizosaccharomyces pombe	67.36	7.00e-118	414.00
IUUC-Ssl-108467	Sclerotinia sclerotiorum	48.84	4.00e-68	249.00
IUUC-Smo-109396	Selaginella moellendorffii	42.17	3.00e-58	216.00
IUUC-Sit-110630	Setaria italica	44.14	1.00e-63	234.00
IUUC-Sly-110972	Solanum lycopersicum	40.88	9.00e-55	204.00
IUUC-Stu-112185	Solanum tuberosum	42.54	1.00e-63	234.00
IUUC-Sar-113294	Sorex araneus	32.52	1.00e-47	181.00
IUUC-Sbi-113951	Sorghum bicolor	42.90	1.00e-62	231.00
IUUC-Ssc-115501	Sus scrofa	37.67	1.00e-54	204.00
IUUC-Tgu-117152	Taeniopygia guttata	37.81	3.00e-52	196.00
IUUC-Tru-118388	Takifugu rubripes	39.87	4.00e-59	219.00
IUUC-Tsy-119109	Tarsius syrichta	38.87	1.00e-59	221.00
IUUC-Tni-120048	Tetraodon nigroviridis	39.87	3.00e-59	219.00
IUUC-Tca-121750	Theobroma cacao	41.88	8.00e-63	231.00
IUUC-Tre-122130	Trichoderma reesei	50.00	1.00e-70	257.00
IUUC-Tvi-122284	Trichoderma virens	50.00	2.00e-69	253.00
IUUC-Tae-124082	Triticum aestivum	43.53	3.00e-65	239.00
IUUC-Tur-126366	Triticum urartu	43.36	1.00e-44	171.00
IUUC-Tme-127187	Tuber melanosporum	49.84	8.00e-86	308.00
IUUC-Tbe-127619	Tupaia belangeri	33.21	2.00e-36	143.00
IUUC-Ttr-128867	Tursiops truncatus	37.18	8.00e-43	165.00
IUUC-Vda-129912	Verticillium dahliae	46.99	7.00e-69	251.00
IUUC-Vpa-130552	Vicugna pacos	42.57	2.00e-47	181.00
IUUC-Vvi-130881	Vitis vinifera	41.40	1.00e-57	214.00
IUUC-Xtr-131934	Xenopus tropicalis	41.53	9.00e-62	228.00
IUUC-Xma-133312	Xiphophorus maculatus	39.66	1.00e-58	218.00
IUUC-Yli-134487	Yarrowia lipolytica	38.31	3.00e-59	219.00
IUUC-Zma-135462	Zea mays	37.13	9.00e-51	191.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence