iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000005837.2	ENSCJAT00000011389.2	ENSCJAP00000010783.2
ENSCJAG00000005837.2	ENSCJAT00000056064.1	ENSCJAP00000044832.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.30e-36	122.0	50	80
UBD/Beta-Prp	6.70e-76	256.3	3	324

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDl 30
           H ++v++++f  + +l+vsG+dD +ikvW++
   Q: 50   HDGPVRGIDFhkQQPLFVSGGDDYKIKVWNY 80
           99********97449**************96 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkg 92
           t +++++++++ + f+p++++++t+  +g i++wd+++ +l+ ++ +h+++v+ ++f+++++++v+g++D+ ikvw+++ + c+ tl g
   Q: 3    TKFETKSARVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLG 91
           67889999********************************************************************************* PP
   S: 93   hedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl............... 166
           h d+++++ f+ +  +++s+s+d+tirvw++++++c+  +l+gh++ v+c+++hp+++l+vs+slD+tvr+Wd+               
   Q: 92   HLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVC-VLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDIsglrkknlspgaves 179
           **************************************.************************************************** PP
   S: 167  ............ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgs 241
                        t+ ++++  +gh++ v++ +f+++++ +vsg++d++vk+w + +++   v+t++gh +nv++  f+p++e+++s s
   Q: 180  dvrgitgvdlfgTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAweVDTCRGHYNNVSCAVFHPRQELILSNS 268
           ************888888888777********************************888888*************************** PP
   S: 242  sDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwklkknep 299
           +D+sir+Wd+ +++ ++t+ + +++++  a+ +++ n +++g  d+   ++kl++++p
   Q: 269  EDKSIRVWDMSKRTGVQTFRRDHDRFWVLAA-HPNLNLFAAG-HDGGMIVFKLERERP 324
           *******************************.5554444444.589999999988765 PP

Organism

Callithrix jacchus

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MLTKFETKSA RVKGLSFHPK RPWILTSLHN GVIQLWDYRM CTLIDKFDEH DGPVRGIDFH 60
KQQPLFVSGG DDYKIKVWNY KLRRCLFTLL GHLDYIRTTF FHHEYPWILS ASDDQTIRVW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTTCCGGAA ACCGTAGCAG AGGGTCGCTG ACGTGGAGGC GACCGAAGGG CAGCAGGGTG 60
TGTCTGGGTT CGGATTAAGA CATCGGAGTC GGAGACCTGA GAGATGCTAA CCAAATTCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0070062--C:extracellular exosome
GO:0005615--C:extracellular space
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0030157--P:pancreatic juice secretion
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000064	Aegilops tauschii	52.31	0.00e+00	1294.00
IUUC-Aml-001758	Ailuropoda melanoleuca	96.76	0.00e+00	2446.00
IUUC-Atr-002493	Amborella trichopoda	61.66	0.00e+00	1075.00
IUUC-Apl-003385	Anas platyrhynchos	92.34	0.00e+00	1979.00
IUUC-Aca-005154	Anolis carolinensis	97.10	3.00e-121	427.00
IUUC-Aly-006020	Arabidopsis lyrata	60.35	0.00e+00	1064.00
IUUC-Ath-007058	Arabidopsis thaliana	60.50	0.00e+00	1057.00
IUUC-Ago-007992	Ashbya gossypii	43.99	0.00e+00	1011.00
IUUC-Acl-008027	Aspergillus clavatus	55.12	0.00e+00	974.00
IUUC-Afl-008644	Aspergillus flavus	47.95	0.00e+00	1158.00
IUUC-Afu-008964	Aspergillus fumigatus	47.86	0.00e+00	1163.00
IUUC-Ani-009379	Aspergillus nidulans	54.71	0.00e+00	979.00
IUUC-Ang-009756	Aspergillus niger	48.51	0.00e+00	1179.00
IUUC-Aor-010174	Aspergillus oryzae	47.95	0.00e+00	1157.00
IUUC-Ate-010302	Aspergillus terreus	48.23	0.00e+00	1197.00
IUUC-Ame-011229	Astyanax mexicanus	84.02	0.00e+00	2133.00
IUUC-Bgr-012300	Blumeria graminis	47.17	0.00e+00	1109.00
IUUC-Bta-012524	Bos taurus	95.78	0.00e+00	2392.00
IUUC-Bci-013781	Botrytis cinerea	47.67	0.00e+00	1167.00
IUUC-Bdi-014549	Brachypodium distachyon	53.46	0.00e+00	1315.00
IUUC-Bol-015925	Brassica oleracea	60.14	0.00e+00	1050.00
IUUC-Bra-016978	Brassica rapa	59.57	0.00e+00	1048.00
IUUC-Cel-018115	Caenorhabditis elegans	61.89	0.00e+00	1092.00
IUUC-Cfa-020675	Canis familiaris	95.17	0.00e+00	2371.00
IUUC-Cpo-021813	Cavia porcellus	95.94	0.00e+00	2417.00
IUUC-Cre-022969	Chlamydomonas reinhardtii	62.77	0.00e+00	1079.00
IUUC-Csa-023523	Chlorocebus sabaeus	96.59	0.00e+00	2441.00
IUUC-Cho-024704	Choloepus hoffmanni	82.80	0.00e+00	1854.00
IUUC-Cin-025572	Ciona intestinalis	71.10	0.00e+00	1846.00
IUUC-Csv-025864	Ciona savignyi	73.29	0.00e+00	1249.00
IUUC-Cgl-026510	Colletotrichum gloeosporioides	55.33	0.00e+00	985.00
IUUC-Cne-027053	Cryptococcus neoformans	51.24	0.00e+00	1230.00
IUUC-Cme-027222	Cyanidioschyzon merolae	40.48	2.00e-138	487.00
IUUC-Dre-027421	Danio rerio	83.95	0.00e+00	2170.00
IUUC-Dno-029303	Dasypus novemcinctus	95.55	0.00e+00	2407.00
IUUC-Dor-030290	Dipodomys ordii	92.92	0.00e+00	1049.00
IUUC-Dse-031543	Dothistroma septosporum	45.52	0.00e+00	1101.00
IUUC-Dme-031945	Drosophila melanogaster	73.10	0.00e+00	1246.00
IUUC-Ete-032873	Echinops telfairi	90.86	0.00e+00	2105.00
IUUC-Eca-033773	Equus caballus	93.68	0.00e+00	2340.00
IUUC-Eeu-034874	Erinaceus europaeus	82.84	0.00e+00	1454.00
IUUC-Fca-035739	Felis catus	94.96	0.00e+00	2355.00
IUUC-Fal-037263	Ficedula albicollis	84.85	0.00e+00	2050.00
IUUC-Fox-037738	Fusarium oxysporum	47.37	0.00e+00	1187.00
IUUC-Fso-038153	Fusarium solani	47.87	0.00e+00	1179.00
IUUC-Gmo-039602	Gadus morhua	78.88	0.00e+00	1986.00
IUUC-Ggr-039931	Gaeumannomyces graminis	54.55	0.00e+00	981.00
IUUC-Gga-040590	Gallus gallus	93.67	0.00e+00	2338.00
IUUC-Gac-041318	Gasterosteus aculeatus	83.73	0.00e+00	2142.00
IUUC-Gma-043894	Glycine max	54.42	0.00e+00	1325.00
IUUC-Ggo-045029	Gorilla gorilla	97.16	0.00e+00	2466.00
IUUC-Hsa-046078	Homo sapiens	97.16	0.00e+00	2466.00
IUUC-Hvu-047556	Hordeum vulgare	54.38	0.00e+00	1328.00
IUUC-Itr-048881	Ictidomys tridecemlineatus	95.56	0.00e+00	1699.00
IUUC-Kpa-049256	Komagataella pastoris	44.13	0.00e+00	1053.00
IUUC-Lch-049706	Latimeria chalumnae	90.59	0.00e+00	2250.00
IUUC-Lpe-051316	Leersia perrieri	52.92	0.00e+00	1290.00
IUUC-Loc-051867	Lepisosteus oculatus	69.09	0.00e+00	1157.00
IUUC-Lma-053138	Leptosphaeria maculans	54.65	0.00e+00	994.00
IUUC-Laf-053510	Loxodonta africana	94.97	0.00e+00	2397.00
IUUC-Mcc-055836	Macaca mulatta	96.76	0.00e+00	2445.00
IUUC-Meu-056238	Macropus eugenii	88.17	0.00e+00	1196.00
IUUC-Mor-057172	Magnaporthe oryzae	47.84	0.00e+00	1165.00
IUUC-Mpo-057300	Magnaporthe poae	47.20	0.00e+00	1152.00
IUUC-Mtr-058248	Medicago truncatula	54.59	0.00e+00	1337.00
IUUC-Mla-059019	Melampsora laricipopulina	56.58	0.00e+00	1027.00
IUUC-Mga-059499	Meleagris gallopavo	93.52	0.00e+00	2332.00
IUUC-Mvi-060336	Microbotryum violaceum	51.77	0.00e+00	1246.00
IUUC-Mmr-061102	Microcebus murinus	95.94	0.00e+00	2417.00
IUUC-Mdo-062594	Monodelphis domestica	94.81	0.00e+00	2435.00
IUUC-Mmu-063736	Mus musculus	96.19	0.00e+00	2433.00
IUUC-Mac-065398	Musa acuminata	51.65	0.00e+00	1228.00
IUUC-Mpu-066701	Mustela putorius furo	95.39	0.00e+00	2362.00
IUUC-Mlu-067392	Myotis lucifugus	94.17	0.00e+00	2368.00
IUUC-Nfi-068270	Neosartorya fischeri	55.24	0.00e+00	975.00
IUUC-Ncr-068892	Neurospora crassa	48.08	0.00e+00	1153.00
IUUC-Nle-069634	Nomascus leucogenys	98.36	0.00e+00	1373.00
IUUC-Opr-070952	Ochotona princeps	84.25	0.00e+00	1756.00
IUUC-Ont-072488	Oreochromis niloticus	85.32	0.00e+00	2156.00
IUUC-Ocu-074211	Oryctolagus cuniculus	96.35	0.00e+00	2426.00
IUUC-Oba-075761	Oryza barthii	52.93	0.00e+00	1300.00
IUUC-Obr-076429	Oryza brachyantha	61.02	0.00e+00	1075.00
IUUC-Ogl-077364	Oryza glaberrima	60.78	0.00e+00	1074.00
IUUC-Ogu-078257	Oryza glumaepatula	60.78	0.00e+00	1073.00
IUUC-Oin-080029	Oryza indica	60.66	0.00e+00	1068.00
IUUC-Olo-080466	Oryza longistaminata	60.91	0.00e+00	1063.00
IUUC-Ome-081668	Oryza meridionalis	62.01	0.00e+00	926.00
IUUC-Oni-082874	Oryza nivara	60.78	0.00e+00	1073.00
IUUC-Opu-083697	Oryza punctata	52.69	0.00e+00	1299.00
IUUC-Oru-084274	Oryza rufipogon	60.78	0.00e+00	1074.00
IUUC-Osa-085565	Oryza sativa	60.78	0.00e+00	1074.00
IUUC-Ola-086921	Oryzias latipes	84.70	0.00e+00	2148.00
IUUC-Olu-087639	Ostreococcus lucimarinus	54.67	0.00e+00	1328.00
IUUC-Oga-087991	Otolemur garnettii	90.95	0.00e+00	2279.00
IUUC-Oar-089590	Ovis aries	95.86	0.00e+00	2416.00
IUUC-Ptr-090808	Pan troglodytes	97.24	0.00e+00	2467.00
IUUC-Pan-092475	Papio anubis	96.11	0.00e+00	2426.00
IUUC-Psi-093044	Pelodiscus sinensis	77.09	0.00e+00	1623.00
IUUC-Pno-094839	Phaeosphaeria nodorum	47.03	0.00e+00	1088.00
IUUC-Ppa-095254	Physcomitrella patens	64.80	0.00e+00	1139.00
IUUC-Pfo-097493	Poecilia formosa	84.83	0.00e+00	2131.00
IUUC-Pab-098497	Pongo abelii	96.59	0.00e+00	2442.00
IUUC-Pop-099992	Populus trichocarpa	55.55	0.00e+00	1313.00
IUUC-Pca-100413	Procavia capensis	91.11	0.00e+00	1039.00
IUUC-Ppe-101899	Prunus persica	54.14	0.00e+00	1295.00
IUUC-Pva-102126	Pteropus vampyrus	92.86	0.00e+00	2328.00
IUUC-Pgr-103376	Puccinia graminis	51.63	0.00e+00	1283.00
IUUC-Ptt-103978	Puccinia triticina	46.37	0.00e+00	1069.00
IUUC-Pte-104126	Pyrenophora teres	54.76	0.00e+00	944.00
IUUC-Pyt-104778	Pyrenophora triticirepentis	44.66	7.00e-168	584.00
IUUC-Rno-105428	Rattus norvegicus	95.38	0.00e+00	2408.00
IUUC-Sce-106464	Saccharomyces cerevisiae	42.78	0.00e+00	988.00
IUUC-Sha-107301	Sarcophilus harrisii	94.84	0.00e+00	2375.00
IUUC-Sja-107961	Schizosaccharomyces japonicus	44.92	0.00e+00	1062.00
IUUC-Spo-108217	Schizosaccharomyces pombe	46.10	0.00e+00	1111.00
IUUC-Ssl-108643	Sclerotinia sclerotiorum	47.67	0.00e+00	1173.00
IUUC-Smo-109582	Selaginella moellendorffii	62.89	0.00e+00	1129.00
IUUC-Sit-109697	Setaria italica	60.55	0.00e+00	1068.00
IUUC-Sly-111447	Solanum lycopersicum	54.00	0.00e+00	1328.00
IUUC-Stu-112564	Solanum tuberosum	53.95	0.00e+00	1331.00
IUUC-Sar-113313	Sorex araneus	85.56	0.00e+00	1431.00
IUUC-Sbi-114388	Sorghum bicolor	53.46	0.00e+00	1317.00
IUUC-Sre-115209	Sporisorium reilianum	56.23	0.00e+00	1018.00
IUUC-Ssc-115933	Sus scrofa	96.03	0.00e+00	2416.00
IUUC-Tgu-117109	Taeniopygia guttata	71.89	0.00e+00	666.00
IUUC-Tru-117772	Takifugu rubripes	84.58	0.00e+00	2133.00
IUUC-Tsy-119105	Tarsius syrichta	84.25	0.00e+00	2096.00
IUUC-Tni-120556	Tetraodon nigroviridis	67.41	0.00e+00	1453.00
IUUC-Tca-121046	Theobroma cacao	54.01	0.00e+00	1345.00
IUUC-Tre-121951	Trichoderma reesei	55.40	0.00e+00	985.00
IUUC-Tvi-122359	Trichoderma virens	55.01	0.00e+00	992.00
IUUC-Tae-125527	Triticum aestivum	52.58	0.00e+00	1291.00
IUUC-Tur-126754	Triticum urartu	60.19	0.00e+00	1068.00
IUUC-Tme-127170	Tuber melanosporum	49.03	0.00e+00	1207.00
IUUC-Tbe-127882	Tupaia belangeri	73.10	0.00e+00	822.00
IUUC-Ttr-128217	Tursiops truncatus	94.57	0.00e+00	2374.00
IUUC-Uma-129337	Ustilago maydis	56.06	0.00e+00	1014.00
IUUC-Vda-129828	Verticillium dahliae	47.69	0.00e+00	1160.00
IUUC-Vpa-130537	Vicugna pacos	96.02	0.00e+00	2405.00
IUUC-Vvi-130958	Vitis vinifera	61.61	0.00e+00	1080.00
IUUC-Xtr-132857	Xenopus tropicalis	87.32	0.00e+00	2199.00
IUUC-Xma-133138	Xiphophorus maculatus	84.59	0.00e+00	2128.00
IUUC-Yli-134399	Yarrowia lipolytica	49.60	0.00e+00	847.00
IUUC-Zma-135612	Zea mays	53.46	0.00e+00	1316.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence