iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cin-025520

Ensembl Protein ID

ENSCINP00000009002.3

UniProt Accession

F6S6B2; F6S6B2_CIOIN

Genbank Protein ID

ENSCINP00000009002

Protein Name

Phosphoinositide phospholipase C

Genbank Nucleotide ID

EAAA01001765

Gene Name

LOC100178711

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCING00000004355.3	ENSCINT00000009002.3	ENSCINP00000009002.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.00e-12	46.1	787	842

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGl.fPenFvekle 63
           +v++lydy a+ ddeLt+ k  ++  +   +qd+gW++g  +  gk G+ fP+n+ve++e
   Q: 787  TVKALYDYRAARDDELTFCKHAIISNV--IKQDGGWWRG--DYGGKAGMwFPSNYVEEME 842
           79**********************988..8*********..9******98*******986 PP

Organism

Ciona intestinalis

Protein Sequence
(Fasta)

MPVQYPNGPT VVHGIVDPKF QNESELQGVL RRLVMGNMMK KIVVRKGKLE ERTFQVNLET 60
RQVVWQRAGV LEGSIDISEI KEIRHGKVSR DFDKLADVSR KLDSAVCFTI LYGNEFNLKI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TACAGCAGGT GTTGAGGTGT ACAAGCAATT GAGAGTATTT CTCGACCTTT TATATCGTTT 60
TACATGTAAT AGCTCAACAA AATGCCGGTC CAATATCCAA ATGGGCCAAC CGTGGTACAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0442--Lipid degradation
KW-0443--Lipid metabolism
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0807--Transducer

Interpro

IPR000008--C2_dom
IPR011992--EF-hand-dom_pair
IPR002048--EF_hand_dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001192--PI-PLC_fam
IPR017946--PLC-like_Pdiesterase_TIM-brl
IPR000909--PLipase_C_PInositol-sp_X_dom
IPR001711--PLipase_C_Pinositol-sp_Y
IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS50222--EF_HAND_2
PS50003--PH_DOMAIN
PS50007--PIPLC_X_DOMAIN
PS50008--PIPLC_Y_DOMAIN
PS50001--SH2
PS50002--SH3

Pfam

PF00168--C2
PF00388--PI-PLC-X
PF00387--PI-PLC-Y
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00390--PHPHLIPASEC
PR00401--SH2DOMAIN

SMART

SM00239--C2
SM00233--PH
SM00148--PLCXc
SM00149--PLCYc
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0005509--F:calcium ion binding
GO:0004435--F:phosphatidylinositol phospholipase C activity
GO:0004871--F:signal transducer activity
GO:0035556--P:intracellular signal transduction
GO:0016042--P:lipid catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001452	Ailuropoda melanoleuca	47.47	0.00e+00	1084.00
IUUC-Apl-003541	Anas platyrhynchos	48.35	0.00e+00	1117.00
IUUC-Aca-005291	Anolis carolinensis	47.77	0.00e+00	1087.00
IUUC-Ame-011004	Astyanax mexicanus	45.85	0.00e+00	1016.00
IUUC-Bta-012660	Bos taurus	48.48	0.00e+00	1049.00
IUUC-Cja-019206	Callithrix jacchus	47.71	0.00e+00	1070.00
IUUC-Cfa-020257	Canis familiaris	48.00	0.00e+00	1055.00
IUUC-Cpo-022391	Cavia porcellus	45.44	0.00e+00	1001.00
IUUC-Csa-024233	Chlorocebus sabaeus	45.45	0.00e+00	1022.00
IUUC-Dre-027944	Danio rerio	44.71	0.00e+00	1008.00
IUUC-Dno-029440	Dasypus novemcinctus	48.07	0.00e+00	1008.00
IUUC-Dor-031001	Dipodomys ordii	47.71	0.00e+00	1077.00
IUUC-Eca-033809	Equus caballus	48.56	0.00e+00	1054.00
IUUC-Eeu-035329	Erinaceus europaeus	44.27	0.00e+00	954.00
IUUC-Fca-036510	Felis catus	48.60	0.00e+00	1053.00
IUUC-Fal-037454	Ficedula albicollis	48.93	0.00e+00	1154.00
IUUC-Gmo-038630	Gadus morhua	48.65	0.00e+00	759.00
IUUC-Gga-040211	Gallus gallus	49.60	0.00e+00	1129.00
IUUC-Ggo-045063	Gorilla gorilla	47.87	0.00e+00	1088.00
IUUC-Hsa-046428	Homo sapiens	47.87	0.00e+00	1088.00
IUUC-Itr-048245	Ictidomys tridecemlineatus	48.29	0.00e+00	1082.00
IUUC-Lch-049766	Latimeria chalumnae	47.60	0.00e+00	1022.00
IUUC-Loc-052285	Lepisosteus oculatus	46.63	0.00e+00	1068.00
IUUC-Laf-053365	Loxodonta africana	48.04	0.00e+00	1048.00
IUUC-Mcc-054871	Macaca mulatta	47.91	0.00e+00	1092.00
IUUC-Meu-056724	Macropus eugenii	45.39	0.00e+00	959.00
IUUC-Mga-059588	Meleagris gallopavo	49.01	0.00e+00	1134.00
IUUC-Mmr-061110	Microcebus murinus	48.35	0.00e+00	1094.00
IUUC-Mdo-062448	Monodelphis domestica	48.59	0.00e+00	1093.00
IUUC-Mmu-063565	Mus musculus	47.86	0.00e+00	1096.00
IUUC-Mpu-066683	Mustela putorius furo	47.81	0.00e+00	1090.00
IUUC-Mlu-067779	Myotis lucifugus	48.14	0.00e+00	1058.00
IUUC-Nle-069219	Nomascus leucogenys	47.78	0.00e+00	954.00
IUUC-Opr-070766	Ochotona princeps	48.65	0.00e+00	679.00
IUUC-Ont-072524	Oreochromis niloticus	46.57	0.00e+00	1062.00
IUUC-Oan-073214	Ornithorhynchus anatinus	54.29	5.00e-29	118.00
IUUC-Ocu-074361	Oryctolagus cuniculus	47.95	0.00e+00	1061.00
IUUC-Ola-086820	Oryzias latipes	46.14	0.00e+00	1047.00
IUUC-Oga-088172	Otolemur garnettii	48.11	0.00e+00	1086.00
IUUC-Oar-090306	Ovis aries	46.66	0.00e+00	1001.00
IUUC-Ptr-090682	Pan troglodytes	47.87	0.00e+00	1088.00
IUUC-Pan-092744	Papio anubis	45.37	0.00e+00	1021.00
IUUC-Psi-093344	Pelodiscus sinensis	47.10	0.00e+00	1083.00
IUUC-Pfo-096984	Poecilia formosa	47.08	0.00e+00	1045.00
IUUC-Pab-097871	Pongo abelii	48.43	0.00e+00	1081.00
IUUC-Pca-100772	Procavia capensis	44.96	0.00e+00	976.00
IUUC-Pva-102790	Pteropus vampyrus	48.15	0.00e+00	1087.00
IUUC-Rno-105974	Rattus norvegicus	47.82	0.00e+00	1097.00
IUUC-Sar-112995	Sorex araneus	48.08	0.00e+00	1065.00
IUUC-Ssc-115360	Sus scrofa	47.81	0.00e+00	1089.00
IUUC-Tgu-116585	Taeniopygia guttata	47.95	0.00e+00	1053.00
IUUC-Tru-117742	Takifugu rubripes	46.28	0.00e+00	1060.00
IUUC-Tsy-119139	Tarsius syrichta	41.68	2.00e-114	405.00
IUUC-Tni-120833	Tetraodon nigroviridis	48.23	0.00e+00	1091.00
IUUC-Tbe-127504	Tupaia belangeri	40.51	2.00e-172	598.00
IUUC-Ttr-128392	Tursiops truncatus	42.85	0.00e+00	931.00
IUUC-Xtr-132708	Xenopus tropicalis	48.80	0.00e+00	1073.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence