iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000013708.10	ENSDART00000135384.2	ENSDARP00000115664.1
ENSDARG00000013708.10	ENSDART00000025635.8	ENSDARP00000026588.8
ENSDARG00000013708.10	ENSDART00000122803.2	ENSDARP00000109728.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.90e-83	280.0	1556	1959

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle................kkkeklneenp............................. 42
           +GlkN g+tCYmNSv+Q+L++ip++r+ +l                 k         +                             
   Q: 1556 VGLKNAGATCYMNSVIQQLYMIPPIRNGILAiegtgsdvdddmsgdeK---------Qdnesnvdprdevfgyqhqfddkpslskse 1633
           6******************************88888877666654331.........033334456677777777777777777776 PP
   S: 43   ..kepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedksels 127
             ke +  +l++lq +f +l +s+ +++ pr ++k+++ + e ++  eq+Da Ef++ l+d+l+e+l                    
   Q: 1634 drKEYNIGVLRQLQVIFGHLASSRLQYYVPRGFWKQFRLWGEPVNLREQHDALEFFNSLVDSLDEAL-------------------- 1700
           6677777************************************************************.................... PP
   S: 128  deaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkk 214
                 k   ++ ++s++++g++ +q +c+ c ++++ ee+f++l++++++++     +l d++e+++k + leg+n+y+cekc+kk
   Q: 1701 ------KALGHPAMLSKVLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQ-----NLLDSMEQYVKGDLLEGANAYHCEKCNKK 1776
           ......67999******************************************.....9**************************** PP
   S: 215  qeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts................peekqke........... 274
           ++++k+l +kklP+vL ++LkRf ++ e+++ +k+n+++efp+eLd++p+++                 +     +           
   Q: 1777 VDTVKRLLIKKLPPVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMEPYTVAgvaklegsdvhpenqqQ-----Viqqnepsepep 1858
           *****************************************************88888888877443330.....366677777888 PP
   S: 275  ..kkkYeLiavvvHsGslssGHYvayvkn........ekgkWllfdDskVtevkeeevleetg........................ 327
             + +Y+L++v+vHsG++s+GHY++y+ +        e+++W++fdD  Vte+k+++ +e+++                        
   Q: 1859 pcSSRYRLVGVLVHSGQASGGHYYSYIIQrngsggegERNRWYKFDDGDVTECKMDDDEEMKNqcfggeymgevfdhmmkrmsyrrq 1945
           8899*************************666665555555*******************9999*********************** PP
   S: 328  ...staYvlfYkrr 338
              ++aY+lfY+r+
   Q: 1946 krwWNAYILFYERM 1959
           ************96 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MTATTRGSPV GGNDGQGQAP DGQSQPPLPQ NQTSSPNSSN ENSPVSPPDD QGQGDSPTPL 60
EEEEPAFPHT ELAKLDDMIN RPRWVVPVLP KGELEVLLEA AIDLCKKGID VKCEACQRFF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTCCATCCG AAGCACGGTG ACGGGTCTCT AAGCAGCCTG ACACAGGAGA GAGAGAGAGC 60
GGCTGGAGGC AGTTTAAGGG AGGGGGGCAG CAGCAGTCGA TGCTGGTGAC GCAGGAAAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005737--C:cytoplasm
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016477--P:cell migration
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001640	Ailuropoda melanoleuca	88.23	0.00e+00	4562.00
IUUC-Apl-003592	Anas platyrhynchos	92.71	0.00e+00	4596.00
IUUC-Aca-004939	Anolis carolinensis	92.51	0.00e+00	4560.00
IUUC-Ame-011772	Astyanax mexicanus	95.32	0.00e+00	4904.00
IUUC-Bta-012775	Bos taurus	87.92	0.00e+00	4528.00
IUUC-Cja-019464	Callithrix jacchus	87.82	0.00e+00	4466.00
IUUC-Cfa-020569	Canis familiaris	89.95	0.00e+00	2963.00
IUUC-Csa-023405	Chlorocebus sabaeus	88.00	0.00e+00	4513.00
IUUC-Cho-024524	Choloepus hoffmanni	89.72	0.00e+00	772.00
IUUC-Cin-025551	Ciona intestinalis	63.00	3.00e-140	491.00
IUUC-Csv-025956	Ciona savignyi	54.00	0.00e+00	2513.00
IUUC-Dno-028936	Dasypus novemcinctus	88.26	0.00e+00	4562.00
IUUC-Dor-030352	Dipodomys ordii	83.71	0.00e+00	2031.00
IUUC-Dme-032160	Drosophila melanogaster	48.46	0.00e+00	2202.00
IUUC-Ete-032287	Echinops telfairi	86.79	0.00e+00	2526.00
IUUC-Eca-033352	Equus caballus	88.42	0.00e+00	4576.00
IUUC-Eeu-034907	Erinaceus europaeus	78.66	0.00e+00	1685.00
IUUC-Fca-035458	Felis catus	88.50	0.00e+00	4582.00
IUUC-Fal-036924	Ficedula albicollis	92.71	0.00e+00	4598.00
IUUC-Gmo-039578	Gadus morhua	92.36	0.00e+00	4651.00
IUUC-Gga-040978	Gallus gallus	92.99	0.00e+00	4602.00
IUUC-Gac-041970	Gasterosteus aculeatus	92.43	0.00e+00	4729.00
IUUC-Ggo-045575	Gorilla gorilla	88.38	0.00e+00	4550.00
IUUC-Hsa-046295	Homo sapiens	88.42	0.00e+00	4549.00
IUUC-Itr-048768	Ictidomys tridecemlineatus	88.34	0.00e+00	4568.00
IUUC-Lch-050493	Latimeria chalumnae	90.75	0.00e+00	4614.00
IUUC-Loc-052667	Lepisosteus oculatus	93.01	0.00e+00	4854.00
IUUC-Laf-054094	Loxodonta africana	88.61	0.00e+00	4571.00
IUUC-Mcc-054861	Macaca mulatta	86.99	0.00e+00	4498.00
IUUC-Meu-056849	Macropus eugenii	75.84	0.00e+00	1311.00
IUUC-Mga-060159	Meleagris gallopavo	92.72	0.00e+00	4591.00
IUUC-Mmr-060732	Microcebus murinus	88.17	0.00e+00	4564.00
IUUC-Mdo-062274	Monodelphis domestica	90.53	0.00e+00	4705.00
IUUC-Mmu-064056	Mus musculus	87.69	0.00e+00	4538.00
IUUC-Mpu-066669	Mustela putorius furo	88.26	0.00e+00	4565.00
IUUC-Mlu-067516	Myotis lucifugus	88.04	0.00e+00	4546.00
IUUC-Nle-069664	Nomascus leucogenys	90.20	0.00e+00	3377.00
IUUC-Opr-070185	Ochotona princeps	81.46	0.00e+00	743.00
IUUC-Ont-072119	Oreochromis niloticus	92.66	0.00e+00	4759.00
IUUC-Oan-073154	Ornithorhynchus anatinus	90.38	0.00e+00	4693.00
IUUC-Ocu-074485	Oryctolagus cuniculus	88.76	0.00e+00	4606.00
IUUC-Ola-086350	Oryzias latipes	93.66	0.00e+00	4650.00
IUUC-Oga-088328	Otolemur garnettii	88.38	0.00e+00	4625.00
IUUC-Oar-090098	Ovis aries	88.26	0.00e+00	4560.00
IUUC-Pan-091741	Papio anubis	90.05	0.00e+00	3528.00
IUUC-Psi-093040	Pelodiscus sinensis	92.84	0.00e+00	4596.00
IUUC-Pfo-096871	Poecilia formosa	92.05	0.00e+00	4733.00
IUUC-Pab-098374	Pongo abelii	88.03	0.00e+00	4512.00
IUUC-Pca-100801	Procavia capensis	82.34	0.00e+00	2241.00
IUUC-Pva-102992	Pteropus vampyrus	84.95	0.00e+00	2236.00
IUUC-Rno-105377	Rattus norvegicus	87.80	0.00e+00	4544.00
IUUC-Sha-106648	Sarcophilus harrisii	88.00	0.00e+00	4529.00
IUUC-Smo-108879	Selaginella moellendorffii	28.30	0.00e+00	834.00
IUUC-Sar-113729	Sorex araneus	88.41	0.00e+00	2845.00
IUUC-Ssc-116261	Sus scrofa	85.20	0.00e+00	4484.00
IUUC-Tgu-117126	Taeniopygia guttata	92.75	0.00e+00	4598.00
IUUC-Tru-117676	Takifugu rubripes	91.89	0.00e+00	4727.00
IUUC-Tsy-119209	Tarsius syrichta	79.47	0.00e+00	2456.00
IUUC-Tni-120207	Tetraodon nigroviridis	91.96	0.00e+00	2096.00
IUUC-Tbe-128033	Tupaia belangeri	85.30	0.00e+00	935.00
IUUC-Ttr-128742	Tursiops truncatus	86.76	0.00e+00	4476.00
IUUC-Vpa-130581	Vicugna pacos	84.88	0.00e+00	4342.00
IUUC-Xtr-132145	Xenopus tropicalis	89.82	0.00e+00	4650.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence