iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000016236.5	ENSGALT00000026178.5	ENSGALP00000026130.3
ENSGALG00000016236.5	ENSGALT00000079252.1	ENSGALP00000050911.1
ENSGALG00000016236.5	ENSGALT00000070712.1	ENSGALP00000051439.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	6.10e-84	282.4	1557	1955

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle................kkkeklneenp............................. 42
           +GlkN g+tCYmNSv+Q+L++ip +r+ +l                 k         +                             
   Q: 1557 VGLKNAGATCYMNSVIQQLYMIPAIRNGILAiegtgsdvdddmsgdeK---------Qdnesnvdprddvfgyphqyedkpalskte 1634
           6******************************88888777666654331.........033334556677787777777777777777 PP
   S: 43   ..kepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedksels 127
             ke +  +l++lq +f +l  s+ +++ pr ++k+++ + e ++  eq+Da Ef++ l+d+l+e+l                    
   Q: 1635 drKEYNIGVLRHLQVIFGHLAASRLQYYVPRGFWKQFRLWGEPVNLREQHDALEFFNSLVDSLDEAL-------------------- 1701
           6677777************************************************************.................... PP
   S: 128  deaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkk 214
                 k   ++ ++s++++g++ +q +c+ c ++++ ee+f++l++++++++     +l d+Le+++k + leg+n+y+cekc+kk
   Q: 1702 ------KALGHPAMLSKVLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQ-----NLLDSLEQYVKGDLLEGANAYHCEKCNKK 1777
           ......67999******************************************.....9**************************** PP
   S: 215  qeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts.....................peekqkekkkYeL 280
           ++++k+l +kklP+vL ++LkRf ++ e+++ +k+n+++efp+eLd++p+++                      +e++ + ++kY+L
   Q: 1778 VDTVKRLLIKKLPPVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMEPYTVAgvaklegddvnpenqiiqneqSENEHSGSTKYRL 1864
           *****************************************************8999999988888888876653333344****** PP
   S: 281  iavvvHsGslssGHYvayvkn......ekgkWllfdDskVtevkeeevleetg...........................staYvlf 334
           ++v+vHsG++s+GHY++y+ +      ek++W++fdD  Vte+k+++ +e+++                           ++aY+lf
   Q: 1865 VGVLVHSGQASGGHYYSYIIQrnggdgEKNRWYKFDDGDVTECKMDDDEEMKNqcfggeymgevfdhmmkrmsyrrqkrwWNAYILF 1951
           *********************6666655666*******************9999********************************* PP
   S: 335  Ykrr 338
           Y+r+
   Q: 1952 YERM 1955
           **96 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MTATTRGSPV GGNDSQGQAP DGQSQPPLQQ NQTSSPDSSN ENSPATPPDE QGQGDAPPQL 60
EDEEPAFPHT DLAKLDDMIN RPRWVVPVLP KGELEVLLEA AIDLSKKGLD VKSEACQRFF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTATGCAAT GGTCTCTGCA GGATGGCATG TTCTTGAGTT GGAGCTTTTT AAAGCAAGCA 60
TATGCTGGTA CTTCAACTTT ACTAAGTGGA CTATAATTTC TTCTCTCACA ACAACTACTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005737--C:cytoplasm
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016477--P:cell migration
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

gga:418569

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001640	Ailuropoda melanoleuca	95.58	0.00e+00	4882.00
IUUC-Apl-003592	Anas platyrhynchos	99.57	0.00e+00	5024.00
IUUC-Aca-004939	Anolis carolinensis	98.35	0.00e+00	4953.00
IUUC-Ame-011772	Astyanax mexicanus	90.43	0.00e+00	4658.00
IUUC-Bta-012775	Bos taurus	95.10	0.00e+00	4831.00
IUUC-Cja-019464	Callithrix jacchus	94.87	0.00e+00	4767.00
IUUC-Cfa-020569	Canis familiaris	94.69	0.00e+00	3132.00
IUUC-Csa-023405	Chlorocebus sabaeus	95.22	0.00e+00	4824.00
IUUC-Cho-024524	Choloepus hoffmanni	91.12	0.00e+00	781.00
IUUC-Cin-025551	Ciona intestinalis	63.75	1.00e-141	496.00
IUUC-Csv-025956	Ciona savignyi	54.09	0.00e+00	2524.00
IUUC-Dre-028329	Danio rerio	90.99	0.00e+00	4689.00
IUUC-Dno-028936	Dasypus novemcinctus	95.50	0.00e+00	4878.00
IUUC-Dor-030352	Dipodomys ordii	90.30	0.00e+00	2170.00
IUUC-Dme-032160	Drosophila melanogaster	48.37	0.00e+00	2202.00
IUUC-Ete-032287	Echinops telfairi	92.33	0.00e+00	2666.00
IUUC-Eca-033352	Equus caballus	94.51	0.00e+00	4865.00
IUUC-Eeu-034907	Erinaceus europaeus	84.95	0.00e+00	1801.00
IUUC-Fca-035458	Felis catus	94.90	0.00e+00	4898.00
IUUC-Fal-036924	Ficedula albicollis	99.48	0.00e+00	4928.00
IUUC-Gmo-039578	Gadus morhua	92.28	0.00e+00	4591.00
IUUC-Gac-041970	Gasterosteus aculeatus	93.10	0.00e+00	4686.00
IUUC-Ggo-045575	Gorilla gorilla	94.63	0.00e+00	4847.00
IUUC-Hsa-046295	Homo sapiens	94.67	0.00e+00	4848.00
IUUC-Itr-048768	Ictidomys tridecemlineatus	95.53	0.00e+00	4880.00
IUUC-Lch-050493	Latimeria chalumnae	95.18	0.00e+00	4766.00
IUUC-Loc-052667	Lepisosteus oculatus	92.82	0.00e+00	4800.00
IUUC-Laf-054094	Loxodonta africana	94.90	0.00e+00	4868.00
IUUC-Mcc-054861	Macaca mulatta	94.12	0.00e+00	4806.00
IUUC-Meu-056849	Macropus eugenii	84.62	0.00e+00	1436.00
IUUC-Mga-060159	Meleagris gallopavo	99.73	0.00e+00	5030.00
IUUC-Mmr-060732	Microcebus murinus	95.39	0.00e+00	4878.00
IUUC-Mdo-062274	Monodelphis domestica	98.43	0.00e+00	5040.00
IUUC-Mmu-064056	Mus musculus	94.83	0.00e+00	4847.00
IUUC-Mpu-066669	Mustela putorius furo	95.61	0.00e+00	4887.00
IUUC-Mlu-067516	Myotis lucifugus	94.91	0.00e+00	4847.00
IUUC-Nle-069664	Nomascus leucogenys	94.76	0.00e+00	3563.00
IUUC-Opr-070185	Ochotona princeps	85.45	0.00e+00	778.00
IUUC-Ont-072119	Oreochromis niloticus	92.42	0.00e+00	4706.00
IUUC-Oan-073154	Ornithorhynchus anatinus	98.16	0.00e+00	5024.00
IUUC-Ocu-074485	Oryctolagus cuniculus	95.02	0.00e+00	4909.00
IUUC-Ola-086350	Oryzias latipes	92.65	0.00e+00	4618.00
IUUC-Oga-088328	Otolemur garnettii	94.43	0.00e+00	4918.00
IUUC-Oar-090098	Ovis aries	94.51	0.00e+00	4855.00
IUUC-Pan-091741	Papio anubis	95.03	0.00e+00	3700.00
IUUC-Psi-093040	Pelodiscus sinensis	98.94	0.00e+00	4990.00
IUUC-Pfo-096871	Poecilia formosa	91.69	0.00e+00	4683.00
IUUC-Pab-098374	Pongo abelii	95.26	0.00e+00	4824.00
IUUC-Pca-100801	Procavia capensis	85.58	0.00e+00	2345.00
IUUC-Pva-102992	Pteropus vampyrus	88.38	0.00e+00	2330.00
IUUC-Rno-105377	Rattus norvegicus	94.95	0.00e+00	4855.00
IUUC-Sha-106648	Sarcophilus harrisii	96.01	0.00e+00	4865.00
IUUC-Smo-108879	Selaginella moellendorffii	28.25	0.00e+00	821.00
IUUC-Sar-113729	Sorex araneus	91.32	0.00e+00	3061.00
IUUC-Ssc-116261	Sus scrofa	90.35	0.00e+00	4718.00
IUUC-Tgu-117126	Taeniopygia guttata	99.65	0.00e+00	5031.00
IUUC-Tru-117676	Takifugu rubripes	92.67	0.00e+00	4682.00
IUUC-Tsy-119209	Tarsius syrichta	83.77	0.00e+00	2607.00
IUUC-Tni-120207	Tetraodon nigroviridis	91.72	0.00e+00	2086.00
IUUC-Tbe-128033	Tupaia belangeri	90.36	0.00e+00	986.00
IUUC-Ttr-128742	Tursiops truncatus	93.69	0.00e+00	4798.00
IUUC-Vpa-130581	Vicugna pacos	92.05	0.00e+00	4675.00
IUUC-Xtr-132145	Xenopus tropicalis	95.50	0.00e+00	4885.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence