iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052518

Ensembl Protein ID

ENSLOCP00000018224.1

UniProt Accession

W5NC65; W5NC65_LEPOC

Genbank Protein ID

ENSLOCP00000018224

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01023861

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000014791.1	ENSLOCT00000018256.1	ENSLOCP00000018224.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.50e-19	67.9	483	512
UBD/Beta-Prp	8.70e-46	156.6	441	736

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWD 29
           H+++v++++   d tl++ G+ D  + +WD
   Q: 483  HEGGVFSVCVlRDgTLVSGGGKDRRVVLWD 512
           9********888845555577********* PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseDrtikvwdls.............. 82
           + +++ c++f+++++  +tg  +g i +w        + +   he++v +v+  +dg +   g++Dr + +wd                
   Q: 441  KPKYVLCIAFAENGD-AITGDSSGNIYIWGKGGNRISQVVaGAHEGGVFSVCVLRDGTLVSGGGKDRRVVLWDSAlqkrqelevpemfg 528
           4456677***99999.689999********9987777777788**************6666678********88888999999****** PP
   S: 83   ...........................tgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvv 144
                                      +g+   +++gh+d+++ l+++p+ + +++ ++d+ +++wd  + q l    +  ++  +++ 
   Q: 529  pvrclaegkqeslfvgttrncilqgslSGELRPIVQGHTDELWGLDVHPNLEQFITCGQDKLVHLWDAVSHQPL--WSKYIEEPARSAG 615
           **************************************************************************..5999999****** PP
   S: 145  vhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlq....tgecvrtlnghtdnvksvr 229
           +hp+g++++ G+  +   + d +t++++   t   ++ +  ++++++g +l+ +s+d+ + l+  +    + + v +++gh+++v+ ++
   Q: 616  FHPSGSVVALGTMTGRWLVLDTETQDVVCAHTD-GNEIISTVKYSPDGAYLAVASHDNFIYLYAASengrKYSRVGKCTGHSSFVTHLD 703
           *****************************9997.889999999**********************986655555*************** PP
   S: 230  fspnderlvsgssDgsiriWdlrsgdllktlqlhn 264
            s +++++v+ s D  i +W  +s+ + ++++  +
   Q: 704  WSVDSQYIVTNSGDYEILFW--ESSSCKHVTNADA 736
           ********************..4666666655544 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

LFIEWGDGGG DRGVDVREGL LIKRGAGKGG EMAERVSSYG NLYDTSSLLQ YCNDDNLSAS 60
SAMEVDDRLS YLEQRVQLQE DEIHVLKAAL ADALRRLGCC EEQSQLFGKR AAPSRVRQLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGAAGTGGAG GCACAACAAA AGTGTCTTAA TTTGATCAAA TGCGTTCAGG TCCTCCCGCT 60
TCACATCGCA GTCGGATATG CTGGACTCCA CGTGGGTTCA CGCGTGTAGT TCCCCCACGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR005108--HELP
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002155	Ailuropoda melanoleuca	67.17	0.00e+00	1021.00
IUUC-Aca-005316	Anolis carolinensis	69.67	0.00e+00	1054.00
IUUC-Ame-011647	Astyanax mexicanus	79.38	0.00e+00	1244.00
IUUC-Bta-013267	Bos taurus	67.36	0.00e+00	1050.00
IUUC-Cfa-020267	Canis familiaris	67.56	0.00e+00	1054.00
IUUC-Dre-028734	Danio rerio	79.31	0.00e+00	1273.00
IUUC-Dno-028961	Dasypus novemcinctus	66.63	0.00e+00	996.00
IUUC-Eca-033785	Equus caballus	67.86	0.00e+00	1055.00
IUUC-Eeu-035302	Erinaceus europaeus	70.30	3.00e-158	551.00
IUUC-Fca-036170	Felis catus	66.58	0.00e+00	1014.00
IUUC-Gmo-039389	Gadus morhua	73.39	0.00e+00	1014.00
IUUC-Gac-042643	Gasterosteus aculeatus	75.31	0.00e+00	1167.00
IUUC-Hsa-046141	Homo sapiens	67.98	0.00e+00	1058.00
IUUC-Itr-048788	Ictidomys tridecemlineatus	67.27	0.00e+00	1046.00
IUUC-Meu-056664	Macropus eugenii	68.18	0.00e+00	918.00
IUUC-Mmr-060853	Microcebus murinus	67.86	0.00e+00	1055.00
IUUC-Mmu-063860	Mus musculus	68.02	0.00e+00	1054.00
IUUC-Mpu-066043	Mustela putorius furo	67.77	0.00e+00	1052.00
IUUC-Ont-071258	Oreochromis niloticus	77.62	0.00e+00	1186.00
IUUC-Ola-086616	Oryzias latipes	73.56	0.00e+00	1070.00
IUUC-Pan-092082	Papio anubis	67.63	0.00e+00	1068.00
IUUC-Pfo-096717	Poecilia formosa	74.76	0.00e+00	1189.00
IUUC-Pca-101070	Procavia capensis	61.50	0.00e+00	824.00
IUUC-Rno-105074	Rattus norvegicus	70.27	0.00e+00	947.00
IUUC-Tru-117809	Takifugu rubripes	72.69	0.00e+00	1191.00
IUUC-Tni-120815	Tetraodon nigroviridis	73.33	0.00e+00	1207.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence