iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-049042

Ensembl Protein ID

ENSSTOP00000016798.1

UniProt Accession

I3MXF3; I3MXF3_ICTTR

Genbank Protein ID

ENSSTOP00000016798

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01018029

Gene Name

RBCK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000026501.1	ENSSTOT00000024134.1	ENSSTOP00000016798.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UBQ/UBQ_Other	7.10e-07	29.0	61	120

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UBQ/UBQ_Other

   S: 5    vksldgseltlk..vnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglk 62
           v++++  + t++  v p++tVa LK++++   g+pp  q++++ G+ L +d  tL ++g++
   Q: 61   VEDAQMHTVTIWltVRPDMTVASLKDMVFLDYGFPPTLQQWVI-GQRLaRDQETLHSHGVR 120
           555555466777779****************************.55555*********996 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MDEKFKKAEE MALSLARAVA GGDEQAAMKC AIWLAEQRVP VSVKLKPEVS LTQDIRLCVS 60
VEDAQMHTVT IWLTVRPDMT VASLKDMVFL DYGFPPTLQQ WVIGQRLARD QETLHSHGVR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTTGGGAGT ATCTGAGTGG GCTGACTTGG ATCTGACACA CATTTTAGCA GGATGTTCTG 60
GTACCTGGGC AGAAGGTGCC TGCAGGTCGG GGAGAGGCTG GCAGAAAAAG AAACAAGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002867--IBR_dom
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR027370--Znf-RING_LisH
IPR001876--Znf_RanBP2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50053--UBIQUITIN_2
PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01485--IBR
PF13445--zf-RING_UBOX

SMART

SM00184--RING
SM00547--ZnF_RBZ

Gene Ontology

GO:0071797--C:LUBAC complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0060546--P:negative regulation of necroptotic process
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:0042346--P:positive regulation of NF-kappaB import into nucleus
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0097039--P:protein linear polyubiquitination
GO:0050852--P:T cell receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001540	Ailuropoda melanoleuca	89.22	0.00e+00	834.00
IUUC-Apl-003627	Anas platyrhynchos	58.44	4.00e-17	78.60
IUUC-Aca-004507	Anolis carolinensis	63.66	9.00e-152	529.00
IUUC-Ame-011008	Astyanax mexicanus	52.26	3.00e-142	498.00
IUUC-Bta-013247	Bos taurus	91.57	0.00e+00	878.00
IUUC-Bci-013637	Botrytis cinerea	27.67	6.00e-13	69.30
IUUC-Cja-018880	Callithrix jacchus	91.37	0.00e+00	876.00
IUUC-Cfa-020477	Canis familiaris	91.18	0.00e+00	876.00
IUUC-Cpo-021558	Cavia porcellus	90.78	0.00e+00	865.00
IUUC-Csa-024129	Chlorocebus sabaeus	92.35	0.00e+00	850.00
IUUC-Cin-025630	Ciona intestinalis	39.58	2.00e-81	296.00
IUUC-Csv-026069	Ciona savignyi	52.80	3.00e-74	270.00
IUUC-Dre-027591	Danio rerio	52.53	5.00e-141	494.00
IUUC-Dno-029015	Dasypus novemcinctus	88.43	0.00e+00	831.00
IUUC-Dor-030313	Dipodomys ordii	83.63	0.00e+00	749.00
IUUC-Ete-032908	Echinops telfairi	80.20	0.00e+00	742.00
IUUC-Eca-034295	Equus caballus	76.29	0.00e+00	710.00
IUUC-Eeu-034454	Erinaceus europaeus	85.42	4.00e-115	408.00
IUUC-Fca-036380	Felis catus	92.55	0.00e+00	887.00
IUUC-Fal-037440	Ficedula albicollis	56.90	2.00e-15	72.80
IUUC-Gmo-038561	Gadus morhua	53.29	7.00e-118	417.00
IUUC-Gga-040198	Gallus gallus	37.76	1.00e-28	119.00
IUUC-Gac-041319	Gasterosteus aculeatus	51.47	2.00e-133	469.00
IUUC-Ggo-044456	Gorilla gorilla	63.97	3.00e-149	521.00
IUUC-Hsa-045738	Homo sapiens	92.94	0.00e+00	847.00
IUUC-Lch-050269	Latimeria chalumnae	43.71	3.00e-111	395.00
IUUC-Loc-052776	Lepisosteus oculatus	50.18	4.00e-137	481.00
IUUC-Laf-054269	Loxodonta africana	88.04	0.00e+00	848.00
IUUC-Mcc-055669	Macaca mulatta	92.55	0.00e+00	859.00
IUUC-Mga-059615	Meleagris gallopavo	53.12	1.00e-16	77.00
IUUC-Mmr-061562	Microcebus murinus	91.80	0.00e+00	765.00
IUUC-Mdo-062263	Monodelphis domestica	75.82	0.00e+00	730.00
IUUC-Mmu-064325	Mus musculus	90.77	0.00e+00	842.00
IUUC-Mpu-066385	Mustela putorius furo	91.37	0.00e+00	877.00
IUUC-Mlu-067000	Myotis lucifugus	90.18	0.00e+00	846.00
IUUC-Nle-069812	Nomascus leucogenys	92.35	0.00e+00	855.00
IUUC-Opr-070575	Ochotona princeps	96.08	4.00e-108	384.00
IUUC-Ont-072405	Oreochromis niloticus	49.71	6.00e-134	470.00
IUUC-Ocu-074358	Oryctolagus cuniculus	81.15	0.00e+00	758.00
IUUC-Ola-086403	Oryzias latipes	52.49	9.00e-137	479.00
IUUC-Oga-087986	Otolemur garnettii	89.80	0.00e+00	823.00
IUUC-Oar-089600	Ovis aries	90.00	0.00e+00	876.00
IUUC-Ptr-091224	Pan troglodytes	92.75	0.00e+00	846.00
IUUC-Pan-092739	Papio anubis	92.75	0.00e+00	862.00
IUUC-Pma-094407	Petromyzon marinus	48.24	2.00e-123	435.00
IUUC-Pfo-097161	Poecilia formosa	51.26	9.00e-131	459.00
IUUC-Pab-098627	Pongo abelii	92.75	0.00e+00	840.00
IUUC-Pca-100641	Procavia capensis	89.52	0.00e+00	794.00
IUUC-Pva-102670	Pteropus vampyrus	91.37	0.00e+00	860.00
IUUC-Pte-104234	Pyrenophora teres	25.13	3.00e-11	63.20
IUUC-Rno-105504	Rattus norvegicus	90.57	0.00e+00	838.00
IUUC-Sha-107342	Sarcophilus harrisii	75.78	0.00e+00	750.00
IUUC-Sar-113425	Sorex araneus	88.58	3.00e-113	401.00
IUUC-Ssc-115904	Sus scrofa	92.49	2.00e-89	320.00
IUUC-Tru-117607	Takifugu rubripes	50.60	4.00e-127	447.00
IUUC-Tni-119873	Tetraodon nigroviridis	50.19	1.00e-136	479.00
IUUC-Tbe-127578	Tupaia belangeri	89.81	0.00e+00	683.00
IUUC-Ttr-129107	Tursiops truncatus	91.57	0.00e+00	842.00
IUUC-Vpa-130353	Vicugna pacos	92.31	5.00e-119	420.00
IUUC-Xtr-132168	Xenopus tropicalis	41.11	7.00e-90	323.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence