iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066385

Ensembl Protein ID

ENSMPUP00000017814.1

UniProt Accession

M3Z2K2; M3Z2K2_MUSPF

Genbank Protein ID

ENSMPUP00000017814

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01020934

Gene Name

RBCK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000017924.1	ENSMPUT00000018074.1	ENSMPUP00000017814.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/NZF	2.90e-11	42.7	195	221
ULD/UDP/UBQ/UBQ_Other	7.70e-07	28.9	60	128

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/NZF

   S: 3    aqWaCsaCTflNePeavkCemCsrpRg 29
            +W+C+ CTf+N+P +++CemC+r R+
   Q: 195  VGWQCPGCTFINKPTRPGCEMCCRARP 221
           68************************8 PP

ULD/UDP/UBQ/UBQ_Other

   S: 4    tvksldgseltlk..vnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglk.dgstihl 69
            v++++  + t++  v p++tVa LK++++   g+pp  q++++ G+ L +d  tL ++g++ +g+t++l
   Q: 60   SVEDAQMHTVTIWltVRPDMTVASLKDMVFLDYGFPPVLQQWVI-GQRLaRDQETLHSHGVRrNGDTAYL 128
           5666665577777889****************************.55555*********99525556555 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MDEKTKKAEE MALRLSRAVA GGDEKVAVQC AIWLAEQRVP LSVRLKPEVS PTQDIRLWVS 60
VEDAQMHTVT IWLTVRPDMT VASLKDMVFL DYGFPPVLQQ WVIGQRLARD QETLHSHGVR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGCATAGCCC TTCTGGGCTG AGGCCATTGA GAGCTGGTGA ACTTACACAC CTTTCGCAGG 60
CACCTTGAGG CCACAGTTTC CCTCGCTACA AGACCGAGGA GGAGGACCGC CAGATCCACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR002867--IBR_dom
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR027370--Znf-RING_LisH
IPR001876--Znf_RanBP2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50053--UBIQUITIN_2
PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01485--IBR
PF13445--zf-RING_UBOX

SMART

SM00184--RING
SM00547--ZnF_RBZ

Gene Ontology

GO:0071797--C:LUBAC complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0060546--P:negative regulation of necroptotic process
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:0042346--P:positive regulation of NF-kappaB import into nucleus
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0097039--P:protein linear polyubiquitination
GO:0050852--P:T cell receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001540	Ailuropoda melanoleuca	94.90	0.00e+00	889.00
IUUC-Apl-003627	Anas platyrhynchos	58.11	5.00e-17	78.60
IUUC-Aca-004507	Anolis carolinensis	63.66	3.00e-152	531.00
IUUC-Ani-009166	Aspergillus nidulans	27.09	2.00e-09	58.20
IUUC-Ame-011008	Astyanax mexicanus	51.38	5.00e-139	487.00
IUUC-Bta-013247	Bos taurus	93.14	0.00e+00	899.00
IUUC-Cja-018880	Callithrix jacchus	93.53	0.00e+00	901.00
IUUC-Cfa-020477	Canis familiaris	96.27	0.00e+00	926.00
IUUC-Cpo-021558	Cavia porcellus	89.22	0.00e+00	853.00
IUUC-Csa-024129	Chlorocebus sabaeus	93.53	0.00e+00	864.00
IUUC-Cin-025630	Ciona intestinalis	39.34	1.00e-81	296.00
IUUC-Csv-026069	Ciona savignyi	51.20	4.00e-72	264.00
IUUC-Dre-027591	Danio rerio	51.56	4.00e-138	484.00
IUUC-Dno-029015	Dasypus novemcinctus	90.20	0.00e+00	852.00
IUUC-Dor-030313	Dipodomys ordii	80.88	0.00e+00	734.00
IUUC-Ete-032908	Echinops telfairi	80.00	0.00e+00	749.00
IUUC-Eca-034295	Equus caballus	76.54	0.00e+00	717.00
IUUC-Eeu-034454	Erinaceus europaeus	85.08	9.00e-115	407.00
IUUC-Fca-036380	Felis catus	97.25	0.00e+00	934.00
IUUC-Fal-037440	Ficedula albicollis	55.56	1.00e-14	70.50
IUUC-Gmo-038561	Gadus morhua	53.62	3.00e-118	418.00
IUUC-Gac-041319	Gasterosteus aculeatus	51.95	4.00e-137	481.00
IUUC-Ggo-044456	Gorilla gorilla	64.62	9.00e-151	526.00
IUUC-Hsa-045738	Homo sapiens	94.71	0.00e+00	865.00
IUUC-Itr-049042	Ictidomys tridecemlineatus	91.37	0.00e+00	855.00
IUUC-Lch-050269	Latimeria chalumnae	43.90	4.00e-113	402.00
IUUC-Loc-052776	Lepisosteus oculatus	50.55	4.00e-139	488.00
IUUC-Laf-054269	Loxodonta africana	90.20	0.00e+00	871.00
IUUC-Mcc-055669	Macaca mulatta	94.31	0.00e+00	875.00
IUUC-Mga-059615	Meleagris gallopavo	56.25	3.00e-17	79.30
IUUC-Mmr-061562	Microcebus murinus	91.61	0.00e+00	764.00
IUUC-Mdo-062263	Monodelphis domestica	77.52	0.00e+00	744.00
IUUC-Mmu-064325	Mus musculus	90.20	0.00e+00	835.00
IUUC-Mlu-067000	Myotis lucifugus	90.98	0.00e+00	858.00
IUUC-Nle-069812	Nomascus leucogenys	94.12	0.00e+00	869.00
IUUC-Opr-070575	Ochotona princeps	94.61	7.00e-107	380.00
IUUC-Ont-071314	Oreochromis niloticus	49.72	2.00e-133	469.00
IUUC-Ocu-074358	Oryctolagus cuniculus	80.81	0.00e+00	760.00
IUUC-Ola-086403	Oryzias latipes	52.18	7.00e-138	483.00
IUUC-Oga-087986	Otolemur garnettii	92.16	0.00e+00	843.00
IUUC-Oar-089600	Ovis aries	91.18	0.00e+00	895.00
IUUC-Ptr-091224	Pan troglodytes	94.51	0.00e+00	864.00
IUUC-Pan-092739	Papio anubis	94.51	0.00e+00	878.00
IUUC-Pma-094407	Petromyzon marinus	46.23	4.00e-124	438.00
IUUC-Pno-094885	Phaeosphaeria nodorum	24.02	9.00e-06	45.40
IUUC-Pfo-097161	Poecilia formosa	51.46	6.00e-132	464.00
IUUC-Pab-098627	Pongo abelii	94.51	0.00e+00	858.00
IUUC-Pca-100641	Procavia capensis	91.61	0.00e+00	820.00
IUUC-Pva-102670	Pteropus vampyrus	93.53	0.00e+00	890.00
IUUC-Pte-104234	Pyrenophora teres	25.41	1.00e-11	64.30
IUUC-Rno-105504	Rattus norvegicus	89.80	0.00e+00	832.00
IUUC-Sha-107342	Sarcophilus harrisii	77.13	0.00e+00	763.00
IUUC-Sar-113425	Sorex araneus	88.13	6.00e-113	400.00
IUUC-Ssc-115904	Sus scrofa	93.06	9.00e-90	322.00
IUUC-Tru-118096	Takifugu rubripes	51.92	3.00e-139	488.00
IUUC-Tni-119873	Tetraodon nigroviridis	48.26	3.00e-135	475.00
IUUC-Tbe-127578	Tupaia belangeri	91.02	0.00e+00	691.00
IUUC-Ttr-129107	Tursiops truncatus	93.73	0.00e+00	856.00
IUUC-Vpa-130353	Vicugna pacos	94.74	5.00e-123	434.00
IUUC-Xtr-132168	Xenopus tropicalis	42.88	1.00e-93	336.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence