iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Meu-056660

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

HECT domain and RCC1-like domain-containing protein 2

Genbank Nucleotide ID

DQ985734

Gene Name

HERC2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMEUG00000000626.1	ENSMEUT00000000680.1	ENSMEUP00000000627.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.70e-86	290.3	4467	4796

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/HECT

   S: 7    krlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknp.....ehlklFeflGrllgkalqdgrll 88
           ++++v+fvgE++ d+gG  +e +a++++elqn  ++l+  ++n++ +   n+d +l np      h+++F+flG+llg+a+++g +l
   Q: 4467 RVWKVKFVGESVDDCGGGYSESIAEMCEELQNGLTPLLIVTPNGRDESGANRDCFLLNPaakssLHTNMFRFLGVLLGIAIRTGSPL 4553
           4566*********************************************************************************** PP
   S: 89   dlplsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvk 175
            l+l+++++k+l g +l++ dl+evd++++  l++i++n+ ++ e +++ l f+     +++++ +++  +++ +++t +N+ eYv+
   Q: 4554 SLNLAEPVWKQLAGMNLTIADLSEVDKDFIPGLMYIRDNEATSEEFEAMSLPFT-----VPSASGQDIQLSSKYTHITLDNRAEYVR 4635
           ***************************************9999999999***99.....788999999******************* PP
   S: 176  lvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerk 262
           l ++yrl+e ++eqv+a+reG+ +v+p  llslFt  ele+++cG+++i ++ lk+ ++ykg ++++ + iqwFwev+e+fs++er+
   Q: 4636 LAINYRLHE-FDEQVAAVREGMARVVPVPLLSLFTGYELETMVCGSPDIPLHLLKSVATYKG-IEPTASLIQWFWEVMESFSNTERS 4720
           *********.**************************************************77.************************ PP
   S: 263  afLqFvTgssrlPlgGfaelkprlfvirk....dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
            fL+Fv+g+ rlP + +a+++ r fvi+     +  d+ lP+s TCf++LkLP+Ys k++l+ekL yAi+ +k++++
   Q: 4721 LFLRFVWGRTRLP-RTIADFRGRDFVIQVldkyNPPDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAIHFCKSIDT 4796
           *************.8*************999988888***********************************99875 PP

Organism

Macropus eugenii

Protein Sequence
(Fasta)

MSSESFCLAA QARFDSKWLK TDLQXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX 60
XXXDTMECQS GTKKEDQNDK EKKDEEETPM PMYRAKSIVE SWVWGKQPXX XXXXXXXXXX 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTTCTG AATCCTTCTG TTTGGCTGCC CAGGCTAGGT TTGACTCCAA GTGGTTGAAA 60
ACAGATTTAC AGGTAAGAGT CTAATGTCAG GTGGTTTTTC TTTTTTTTTT CCCTGTTATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Gene Ontology

GO:0005743--C:mitochondrial inner membrane
GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0006974--P:cellular response to DNA damage stimulus
GO:0007283--P:spermatogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002112	Ailuropoda melanoleuca	96.40	0.00e+00	1942.00
IUUC-Atr-003065	Amborella trichopoda	34.28	4.00e-42	166.00
IUUC-Apl-003983	Anas platyrhynchos	98.05	0.00e+00	1954.00
IUUC-Aca-004300	Anolis carolinensis	97.57	0.00e+00	1950.00
IUUC-Aly-006545	Arabidopsis lyrata	35.53	2.00e-44	174.00
IUUC-Ame-010621	Astyanax mexicanus	94.65	0.00e+00	1895.00
IUUC-Bta-013067	Bos taurus	95.68	0.00e+00	1914.00
IUUC-Bdi-014093	Brachypodium distachyon	34.26	8.00e-43	168.00
IUUC-Bol-015203	Brassica oleracea	34.28	1.00e-45	178.00
IUUC-Bra-016737	Brassica rapa	33.75	1.00e-43	171.00
IUUC-Cja-019687	Callithrix jacchus	95.14	0.00e+00	1894.00
IUUC-Cfa-020672	Canis familiaris	96.40	0.00e+00	1944.00
IUUC-Cpo-021819	Cavia porcellus	95.92	0.00e+00	1934.00
IUUC-Csa-023817	Chlorocebus sabaeus	96.21	0.00e+00	1935.00
IUUC-Cho-024387	Choloepus hoffmanni	97.88	0.00e+00	639.00
IUUC-Cin-025709	Ciona intestinalis	64.57	0.00e+00	1261.00
IUUC-Csv-026336	Ciona savignyi	64.47	0.00e+00	1287.00
IUUC-Dre-027717	Danio rerio	94.26	0.00e+00	1887.00
IUUC-Dno-029296	Dasypus novemcinctus	95.33	0.00e+00	1912.00
IUUC-Dor-030979	Dipodomys ordii	96.82	0.00e+00	1082.00
IUUC-Dme-032171	Drosophila melanogaster	64.32	0.00e+00	1316.00
IUUC-Ete-032687	Echinops telfairi	85.03	5.00e-145	510.00
IUUC-Eca-034046	Equus caballus	96.40	0.00e+00	1943.00
IUUC-Eeu-034859	Erinaceus europaeus	95.53	0.00e+00	957.00
IUUC-Fca-036262	Felis catus	96.30	0.00e+00	1943.00
IUUC-Fal-037562	Ficedula albicollis	97.86	0.00e+00	1951.00
IUUC-Gmo-038739	Gadus morhua	90.21	0.00e+00	1016.00
IUUC-Gga-040359	Gallus gallus	97.96	0.00e+00	1951.00
IUUC-Gac-041879	Gasterosteus aculeatus	90.57	0.00e+00	1027.00
IUUC-Ggo-044692	Gorilla gorilla	95.82	0.00e+00	1922.00
IUUC-Hsa-045995	Homo sapiens	96.30	0.00e+00	1938.00
IUUC-Hvu-047529	Hordeum vulgare	35.77	2.00e-44	174.00
IUUC-Itr-048553	Ictidomys tridecemlineatus	85.17	6.00e-171	595.00
IUUC-Lch-049808	Latimeria chalumnae	96.51	0.00e+00	1924.00
IUUC-Loc-052685	Lepisosteus oculatus	95.73	0.00e+00	1920.00
IUUC-Laf-053372	Loxodonta africana	95.43	0.00e+00	1926.00
IUUC-Mcc-054693	Macaca mulatta	95.91	0.00e+00	1935.00
IUUC-Mga-059371	Meleagris gallopavo	97.77	0.00e+00	1947.00
IUUC-Mmr-060787	Microcebus murinus	96.40	0.00e+00	1939.00
IUUC-Mdo-062518	Monodelphis domestica	87.72	0.00e+00	1726.00
IUUC-Mmu-063690	Mus musculus	96.30	0.00e+00	1924.00
IUUC-Mpu-066478	Mustela putorius furo	96.30	0.00e+00	1940.00
IUUC-Mlu-067596	Myotis lucifugus	94.56	0.00e+00	629.00
IUUC-Opr-070990	Ochotona princeps	95.48	0.00e+00	1908.00
IUUC-Ont-072285	Oreochromis niloticus	94.16	0.00e+00	1885.00
IUUC-Oan-072721	Ornithorhynchus anatinus	96.31	0.00e+00	1922.00
IUUC-Ocu-074273	Oryctolagus cuniculus	96.17	0.00e+00	1920.00
IUUC-Ola-087346	Oryzias latipes	92.37	0.00e+00	1177.00
IUUC-Oga-088742	Otolemur garnettii	95.72	0.00e+00	1929.00
IUUC-Oar-090093	Ovis aries	95.87	0.00e+00	1919.00
IUUC-Ptr-091034	Pan troglodytes	83.88	0.00e+00	1645.00
IUUC-Pan-092783	Papio anubis	96.21	0.00e+00	1936.00
IUUC-Psi-094027	Pelodiscus sinensis	97.67	0.00e+00	1945.00
IUUC-Pfo-097354	Poecilia formosa	91.90	0.00e+00	1036.00
IUUC-Pab-097681	Pongo abelii	86.01	2.00e-176	612.00
IUUC-Pva-103147	Pteropus vampyrus	88.49	0.00e+00	882.00
IUUC-Rno-105458	Rattus norvegicus	96.30	0.00e+00	1924.00
IUUC-Sha-106959	Sarcophilus harrisii	89.65	0.00e+00	1719.00
IUUC-Smo-108827	Selaginella moellendorffii	34.22	1.00e-41	164.00
IUUC-Sly-110961	Solanum lycopersicum	36.34	1.00e-48	188.00
IUUC-Sar-113532	Sorex araneus	89.29	9.00e-167	582.00
IUUC-Sbi-114352	Sorghum bicolor	31.25	4.00e-44	173.00
IUUC-Ssc-116304	Sus scrofa	96.81	0.00e+00	962.00
IUUC-Tgu-116789	Taeniopygia guttata	97.67	0.00e+00	1946.00
IUUC-Tru-118129	Takifugu rubripes	93.97	0.00e+00	1882.00
IUUC-Tsy-119302	Tarsius syrichta	90.00	1.00e-170	596.00
IUUC-Tni-120374	Tetraodon nigroviridis	93.30	0.00e+00	1866.00
IUUC-Tae-124157	Triticum aestivum	34.44	9.00e-43	168.00
IUUC-Tur-126300	Triticum urartu	35.77	9.00e-45	175.00
IUUC-Tbe-128137	Tupaia belangeri	93.48	0.00e+00	792.00
IUUC-Ttr-128273	Tursiops truncatus	93.84	0.00e+00	1285.00
IUUC-Vpa-130471	Vicugna pacos	75.00	1.00e-153	539.00
IUUC-Xtr-132185	Xenopus tropicalis	95.43	0.00e+00	1907.00
IUUC-Xma-133233	Xiphophorus maculatus	94.16	0.00e+00	1855.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence