iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-001482

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01116254

Gene Name

TEP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000005467.1	ENSAMET00000006083.1	ENSAMEP00000005839.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.30e-52	172.2	2116	2149
UBD/Beta-Prp	1.90e-71	240.8	2018	2199

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sdtllvsGsdDgtikvWDlrtgv 34
           H d+vt++++  d+llvs+s Dg++ +WD+ ++ 
   Q: 2116 HRDWVTGCDWtKDNLLVSCSTDGSVGLWDPERQQ 2149
           9*********877****************87665 PP

UBD/Beta-Prp

   S: 48   lsgheaevtavkfspdgkilvtgseDrtikvw.........dlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdlet 125
           ls  +++v  +  s++  +l+++seD t+++w           ++++c   l++he  v +++fs +g +l++G++dr + +wd++ 
   Q: 2018 LSRYQKPVLGLATSSE--LLASASEDFTVRLWprqpltlaqTAEDFPCGTELREHEGPVSCCRFSSDGGRLATGGRDRNLFCWDVRM 2102
           5666777788888888..9*************666555555555*****************************************99 PP
   S: 126  gqclee...tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdl 209
            +       + + h+++v++  + + +nllvs+s+D+ v lWd ++++ l ++ g h+++v  +   +  +++vs+++dgt+k+wd 
   Q: 2103 PKAPVLicsFSACHRDWVTGCDWTK-DNLLVSCSTDGSVGLWDPERQQQLGQFLG-HQSAVSAVVAVE--EHVVSVGRDGTLKVWDH 2185
           887665677999***********99.9***************************9.******999888..69**************9 PP
   S: 210  qtgecvrtlnghtdn 224
           q  e + +  +h+ +
   Q: 2186 QGVE-LTSIPAHSGP 2199
           8544.5566666555 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MEKLQGHASS HLDILSLENR CLATLPNLQP MKKPHGHVSA HPDILSLENQ CLATLPDLKT 60
MEKPHGHVSA HPDILSLENR CLATLPDLKT MEKPHGHVSA HPDILSLENR CLATLPVLKS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGAAAC TCCAAGGACA TGCATCTTCC CACTTGGACA TTCTCTCCTT AGAGAACCGG 60
TGCCTGGCCA CACTCCCCAA CCTGCAGCCC ATGAAGAAAC CACATGGGCA TGTGTCTGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR025139--DUF4062
IPR007111--NACHT_NTPase
IPR027417--P-loop_NTPase
IPR023302--Pept_S9A_N
IPR011047--Quinoprotein_ADH-like_supfam
IPR008850--TEP1_N
IPR008858--TROVE_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50837--NACHT
PS51226--TEP1_N
PS50988--TROVE
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13271--DUF4062
PF05386--TEP1_N
PF05731--TROVE
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0005697--C:telomerase holoenzyme complex
GO:0003720--F:telomerase activity
GO:0070034--F:telomerase RNA binding
GO:0000722--P:telomere maintenance via recombination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-005102	Anolis carolinensis	42.34	0.00e+00	1634.00
IUUC-Ame-011165	Astyanax mexicanus	34.25	9.00e-151	528.00
IUUC-Bta-012323	Bos taurus	78.82	0.00e+00	3852.00
IUUC-Cja-019005	Callithrix jacchus	78.73	0.00e+00	3967.00
IUUC-Cfa-020803	Canis familiaris	79.05	0.00e+00	3712.00
IUUC-Cpo-022312	Cavia porcellus	72.41	0.00e+00	3322.00
IUUC-Csa-023287	Chlorocebus sabaeus	79.30	0.00e+00	3923.00
IUUC-Dre-028825	Danio rerio	34.61	0.00e+00	1170.00
IUUC-Dno-029455	Dasypus novemcinctus	76.35	0.00e+00	3620.00
IUUC-Dor-030328	Dipodomys ordii	70.16	0.00e+00	2378.00
IUUC-Ete-032385	Echinops telfairi	71.24	0.00e+00	1871.00
IUUC-Eca-033726	Equus caballus	82.34	0.00e+00	4044.00
IUUC-Eeu-034665	Erinaceus europaeus	62.44	0.00e+00	960.00
IUUC-Fca-035365	Felis catus	84.96	0.00e+00	4205.00
IUUC-Gmo-039584	Gadus morhua	31.04	1.00e-114	408.00
IUUC-Gac-042307	Gasterosteus aculeatus	36.24	0.00e+00	1016.00
IUUC-Ggo-045432	Gorilla gorilla	76.42	0.00e+00	3672.00
IUUC-Hsa-046182	Homo sapiens	78.50	0.00e+00	3921.00
IUUC-Itr-049021	Ictidomys tridecemlineatus	76.03	0.00e+00	3755.00
IUUC-Lch-050186	Latimeria chalumnae	38.56	9.00e-77	280.00
IUUC-Laf-054524	Loxodonta africana	75.86	0.00e+00	3778.00
IUUC-Mcc-055628	Macaca mulatta	79.57	0.00e+00	3939.00
IUUC-Meu-056338	Macropus eugenii	62.48	0.00e+00	1268.00
IUUC-Mmr-060854	Microcebus murinus	78.57	0.00e+00	3833.00
IUUC-Mdo-062247	Monodelphis domestica	59.88	0.00e+00	2701.00
IUUC-Mmu-064406	Mus musculus	70.94	0.00e+00	3403.00
IUUC-Mpu-065806	Mustela putorius furo	88.75	0.00e+00	4417.00
IUUC-Mlu-068116	Myotis lucifugus	80.74	0.00e+00	3838.00
IUUC-Nle-069628	Nomascus leucogenys	79.23	0.00e+00	3492.00
IUUC-Opr-070242	Ochotona princeps	76.00	0.00e+00	2673.00
IUUC-Oan-073598	Ornithorhynchus anatinus	52.22	0.00e+00	1898.00
IUUC-Ocu-073933	Oryctolagus cuniculus	76.73	0.00e+00	3679.00
IUUC-Ola-086886	Oryzias latipes	35.35	0.00e+00	1068.00
IUUC-Oga-088609	Otolemur garnettii	76.68	0.00e+00	3727.00
IUUC-Oar-089957	Ovis aries	78.48	0.00e+00	3769.00
IUUC-Ptr-090577	Pan troglodytes	77.11	0.00e+00	3856.00
IUUC-Pan-092397	Papio anubis	79.30	0.00e+00	3935.00
IUUC-Pma-094373	Petromyzon marinus	34.71	2.00e-70	260.00
IUUC-Pfo-096497	Poecilia formosa	36.55	0.00e+00	1070.00
IUUC-Pab-098028	Pongo abelii	78.47	0.00e+00	3897.00
IUUC-Pca-101002	Procavia capensis	80.64	0.00e+00	1811.00
IUUC-Pva-102144	Pteropus vampyrus	73.30	0.00e+00	1709.00
IUUC-Rno-105828	Rattus norvegicus	70.82	0.00e+00	3486.00
IUUC-Sha-106469	Sarcophilus harrisii	59.20	0.00e+00	2774.00
IUUC-Sar-113035	Sorex araneus	76.66	0.00e+00	1451.00
IUUC-Ssc-116122	Sus scrofa	80.55	0.00e+00	2900.00
IUUC-Tru-118412	Takifugu rubripes	32.36	0.00e+00	1149.00
IUUC-Tsy-119257	Tarsius syrichta	71.70	0.00e+00	1450.00
IUUC-Tni-120032	Tetraodon nigroviridis	35.53	2.00e-42	166.00
IUUC-Tbe-127312	Tupaia belangeri	72.93	0.00e+00	792.00
IUUC-Ttr-128335	Tursiops truncatus	76.51	0.00e+00	3782.00
IUUC-Xtr-132524	Xenopus tropicalis	40.15	0.00e+00	1384.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence