iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000016255.3	ENSMMUT00000022840.3	ENSMMUP00000021364.3
ENSMMUG00000016255.3	ENSMMUT00000022841.3	ENSMMUP00000021365.3
ENSMMUG00000016255.3	ENSMMUT00000076827.1	ENSMMUP00000044148.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.60e-55	181.9	2107	2139
UBD/Beta-Prp	7.90e-78	262.8	1934	2176

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sdtllvsGsdDgtikvWDlrtg 33
           H d+vt++a+  d+ll+s+s Dg++ +WD+ +g
   Q: 2107 HRDWVTGCAWtKDNLLISCSSDGSVGLWDPESG 2139
           9*********877****************8877 PP

UBD/Beta-Prp

   S: 58   vkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee.tlsghdgvvncv 143
           v +spdg+  + g + + i+++ +s+g++    ++ +  v +l++    ++lvsG +d  ++ w l++ +  +  +ls  ++ v ++
   Q: 1934 VALSPDGDRVAVGYRADGIRIYKISSGSQGAQGQALDVAVSALAWLS-PKVLVSGAEDGSLQGWALKECSLQSLwLLSRFQKPVLGL 2019
           66778888888888888888888888888888888888888888876.688888888888888877654433336777777777777 PP
   S: 144  vvhpdgnllvsGslDrtvrlWdlktgkllrtl.........tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec...vrtl 218
           ++++   ll+s+s D tvrlW  +  +l ++          +g h+++v + sf+ +g +l++g++d+++  wd++t +    ++++
   Q: 2020 ATSQ--ELLASASEDFTVRLWPRQLLTLPHKAedfpggtelRG-HEGPVSCCSFSTDGGSLATGGRDRSLLCWDVRTPKApilIHSF 2103
           7777..8888888888888888866666666566677777565.8888888888888888888888888888888877767777777 PP
   S: 219  ng.htdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwkl 294
            + h+d+v+  + + +d++l+s+ssDgs+ +Wd +sg+ l+++ +h+s v++va+    + ++v+++ d+++++w+ 
   Q: 2104 PAcHRDWVTGCAWT-KDNLLISCSSDGSVGLWDPESGQRLGQFLGHQSAVSAVAA---VEEHVVSVGRDGTLKVWDH 2176
           65588888888777.8888888888888888888888888888888888888888...6778888888888888875 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MEKPHGHVSA HPDILSLENR CLAMLPDLQP MEKLHQHISA HSDILSLKNQ CLATLPDLKT 60
VEKPHGYVSA HPDILSLENR CLATLSDLKT MEKPHGHVSA HPDILSLENR CLATLPSLKS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGCCGCGCC CCGCCCGGGC CCGAGAGTCT CCGCCCGCAC TGTCTCTTCC CAGATCCGCA 60
TCCGGCTCCT CCCCCGGCTG CCACCCTTCC CACTGGCAGA ACCCAGAGCG AAGTTTCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR025139--DUF4062
IPR007111--NACHT_NTPase
IPR027417--P-loop_NTPase
IPR011047--Quinoprotein_ADH-like_supfam
IPR008850--TEP1_N
IPR008858--TROVE_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50837--NACHT
PS51226--TEP1_N
PS50988--TROVE
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13271--DUF4062
PF05386--TEP1_N
PF05731--TROVE
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0071011--C:precatalytic spliceosome
GO:0005697--C:telomerase holoenzyme complex
GO:0005682--C:U5 snRNP
GO:0003720--F:telomerase activity
GO:0070034--F:telomerase RNA binding
GO:0008380--P:RNA splicing
GO:0000722--P:telomere maintenance via recombination

KEGG

mcc:703733

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001482	Ailuropoda melanoleuca	79.68	0.00e+00	3920.00
IUUC-Aca-005102	Anolis carolinensis	42.81	0.00e+00	1672.00
IUUC-Ame-011822	Astyanax mexicanus	34.68	0.00e+00	638.00
IUUC-Bta-012323	Bos taurus	80.31	0.00e+00	3974.00
IUUC-Cja-019005	Callithrix jacchus	92.51	0.00e+00	4813.00
IUUC-Cfa-020803	Canis familiaris	72.38	0.00e+00	3470.00
IUUC-Cpo-022312	Cavia porcellus	75.17	0.00e+00	3545.00
IUUC-Csa-023287	Chlorocebus sabaeus	98.51	0.00e+00	5048.00
IUUC-Dre-028825	Danio rerio	35.51	0.00e+00	1163.00
IUUC-Dno-029455	Dasypus novemcinctus	79.47	0.00e+00	3844.00
IUUC-Dor-030328	Dipodomys ordii	74.14	0.00e+00	2606.00
IUUC-Ete-032385	Echinops telfairi	74.73	0.00e+00	1965.00
IUUC-Eca-033726	Equus caballus	83.83	0.00e+00	4210.00
IUUC-Eeu-034665	Erinaceus europaeus	63.71	0.00e+00	981.00
IUUC-Fca-035365	Felis catus	80.65	0.00e+00	4007.00
IUUC-Gmo-039584	Gadus morhua	32.18	7.00e-126	446.00
IUUC-Gac-042307	Gasterosteus aculeatus	35.83	0.00e+00	1026.00
IUUC-Ggo-045432	Gorilla gorilla	92.99	0.00e+00	4583.00
IUUC-Hsa-046182	Homo sapiens	95.43	0.00e+00	4889.00
IUUC-Itr-049021	Ictidomys tridecemlineatus	80.69	0.00e+00	4048.00
IUUC-Lch-050186	Latimeria chalumnae	39.34	2.00e-80	293.00
IUUC-Laf-054524	Loxodonta africana	79.75	0.00e+00	4034.00
IUUC-Meu-056338	Macropus eugenii	63.64	0.00e+00	1302.00
IUUC-Mmr-060854	Microcebus murinus	84.47	0.00e+00	4214.00
IUUC-Mdo-062247	Monodelphis domestica	60.66	0.00e+00	2823.00
IUUC-Mmu-064406	Mus musculus	75.24	0.00e+00	3724.00
IUUC-Mpu-065806	Mustela putorius furo	78.79	0.00e+00	3953.00
IUUC-Mlu-068116	Myotis lucifugus	81.67	0.00e+00	3970.00
IUUC-Nle-069628	Nomascus leucogenys	93.90	0.00e+00	4281.00
IUUC-Opr-070242	Ochotona princeps	79.60	0.00e+00	2900.00
IUUC-Oan-073598	Ornithorhynchus anatinus	53.09	0.00e+00	1956.00
IUUC-Ocu-073933	Oryctolagus cuniculus	80.95	0.00e+00	3971.00
IUUC-Ola-086886	Oryzias latipes	35.30	0.00e+00	1071.00
IUUC-Oga-088609	Otolemur garnettii	81.48	0.00e+00	4021.00
IUUC-Oar-089957	Ovis aries	79.31	0.00e+00	3853.00
IUUC-Ptr-090577	Pan troglodytes	93.91	0.00e+00	4809.00
IUUC-Pan-092397	Papio anubis	98.51	0.00e+00	5039.00
IUUC-Pma-094373	Petromyzon marinus	35.16	2.00e-77	283.00
IUUC-Pfo-096497	Poecilia formosa	36.05	0.00e+00	1080.00
IUUC-Pab-098028	Pongo abelii	95.21	0.00e+00	4826.00
IUUC-Pca-101002	Procavia capensis	83.57	0.00e+00	1917.00
IUUC-Pva-102144	Pteropus vampyrus	75.00	0.00e+00	1749.00
IUUC-Rno-105828	Rattus norvegicus	74.92	0.00e+00	3775.00
IUUC-Sha-106469	Sarcophilus harrisii	60.85	0.00e+00	2904.00
IUUC-Sar-113035	Sorex araneus	77.72	0.00e+00	1472.00
IUUC-Ssc-116122	Sus scrofa	83.21	0.00e+00	3024.00
IUUC-Tru-118412	Takifugu rubripes	33.03	0.00e+00	1163.00
IUUC-Tsy-119257	Tarsius syrichta	77.49	0.00e+00	1643.00
IUUC-Tni-120032	Tetraodon nigroviridis	33.99	7.00e-41	160.00
IUUC-Tbe-127312	Tupaia belangeri	69.08	0.00e+00	1033.00
IUUC-Ttr-128335	Tursiops truncatus	80.77	0.00e+00	3474.00
IUUC-Xtr-132524	Xenopus tropicalis	39.67	0.00e+00	1406.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence