iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132524

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Telomerase-associated protein 1

Genbank Nucleotide ID

AAMC01032097

Gene Name

tep1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000001751.3	ENSXETT00000035244.3	ENSXETP00000035244.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.10e-43	144.6	1859	1888
UBD/Beta-Prp	1.20e-87	294.0	1687	1941

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclafsd.tllvsGsdDgtikvWDl 30
           H d+vt+++++d ++lvs+s+Dg++ +WD+
   Q: 1859 HRDWVTACSWTDaDMLVSCSGDGSVCLWDI 1888
           9*********999****************6 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdls..tgkcvhtlkghedsv 97
           i+ +++sp+++lla+g+ +gt+ v++v+ g+l+++ s  + ++ +v + +++ +lvtg +D +++vw +s  +++c   lk+h++ v
   Q: 1687 IS-LAVSPSRQLLAVGYHTGTVSVYSVDLGDLVAQTSIEDVTILCVAWLSEE-VLVTGTSDSLVRVWKISsgQFTCQLMLKEHQRFV 1771
           44.889*********************************************8.**************8886688999999******* PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqclee......tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl..ktgkllrtlt 176
            +l++s   + l+s+s d  + +w l++   + +      +l+gh+++v+c +++ +g+ll++Gs Dr v  Wd+     ++++ l 
   Q: 1772 QALAVSS--KLLASASGDVSVCLWSLNSLLNSVSppspasVLQGHSAAVTCCSFSRNGKLLATGSQDRSVLCWDVslIPPSVVHALP 1856
           *******..***************99999998889****************************************65569******9 PP
   S: 177  gghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlh 263
           + h d v+  s+++    lvs+s dg+v lwd+q++e +  + gh++ v+s      +er++++s Dg +++W+l   ++ +  +++
   Q: 1857 SCHRDWVTACSWTDA-DMLVSCSGDGSVCLWDIQREERLLDFAGHQSAVSSAICM--GERVITTSRDGCLKVWNLAGLEVANISAHQ 1940
           99***********95.79**********************************999..*****************9887777766655 PP
   S: 264  n 264
           +
   Q: 1941 E 1941
           4 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

QMELVSAVCC SLVRGPKFSD SCDETRVKLL ALCEELSNLD PEFILKVALY TRQELNIRST 60
ANFMLAVSAF LPACRPHLRR YFCASVQLPA DWMEIPRLYQ SLAGQGEKLA PLPSCLRRVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGATGGAGC TGGTCTCTGC TGTCTGCTGC TCACTAGTAC GTGGGCCCAA GTTTTCTGAT 60
AGCTGTGATG AGACCCGGGT AAAGCTTCTA GCACTTTGTG AGGAGCTGTC TAACCTGGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR025139--DUF4062
IPR008858--TROVE_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50988--TROVE
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF13271--DUF4062
PF05731--TROVE
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0071011--C:precatalytic spliceosome
GO:0005682--C:U5 snRNP
GO:0003723--F:RNA binding
GO:0008380--P:RNA splicing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001482	Ailuropoda melanoleuca	40.39	0.00e+00	1380.00
IUUC-Aca-005102	Anolis carolinensis	42.00	0.00e+00	1481.00
IUUC-Ame-011822	Astyanax mexicanus	32.99	0.00e+00	893.00
IUUC-Bta-012323	Bos taurus	39.21	0.00e+00	1350.00
IUUC-Cja-019005	Callithrix jacchus	39.63	0.00e+00	1476.00
IUUC-Cfa-020803	Canis familiaris	39.01	0.00e+00	1286.00
IUUC-Cpo-022312	Cavia porcellus	39.52	0.00e+00	1384.00
IUUC-Csa-023287	Chlorocebus sabaeus	40.09	0.00e+00	1427.00
IUUC-Cin-025646	Ciona intestinalis	24.88	7.00e-22	99.40
IUUC-Dre-028825	Danio rerio	36.36	0.00e+00	1169.00
IUUC-Dno-029455	Dasypus novemcinctus	38.87	0.00e+00	844.00
IUUC-Dor-030328	Dipodomys ordii	36.82	0.00e+00	900.00
IUUC-Ete-032385	Echinops telfairi	40.41	0.00e+00	832.00
IUUC-Eca-033726	Equus caballus	40.06	0.00e+00	1421.00
IUUC-Eeu-034665	Erinaceus europaeus	38.16	1.00e-111	399.00
IUUC-Fca-035365	Felis catus	39.75	0.00e+00	1409.00
IUUC-Gmo-039584	Gadus morhua	31.88	8.00e-127	449.00
IUUC-Gac-042307	Gasterosteus aculeatus	35.91	0.00e+00	1030.00
IUUC-Ggo-045432	Gorilla gorilla	38.12	0.00e+00	1352.00
IUUC-Hsa-046182	Homo sapiens	39.40	0.00e+00	1429.00
IUUC-Itr-049021	Ictidomys tridecemlineatus	39.41	0.00e+00	1428.00
IUUC-Lch-050186	Latimeria chalumnae	39.77	2.00e-91	329.00
IUUC-Laf-054524	Loxodonta africana	38.81	0.00e+00	1395.00
IUUC-Mcc-055628	Macaca mulatta	40.04	0.00e+00	1429.00
IUUC-Meu-056338	Macropus eugenii	39.48	0.00e+00	749.00
IUUC-Mmr-060854	Microcebus murinus	39.27	0.00e+00	1409.00
IUUC-Mdo-062247	Monodelphis domestica	39.56	0.00e+00	1393.00
IUUC-Mmu-064406	Mus musculus	39.34	0.00e+00	1363.00
IUUC-Mpu-065806	Mustela putorius furo	39.38	0.00e+00	1378.00
IUUC-Mlu-068116	Myotis lucifugus	38.83	0.00e+00	1321.00
IUUC-Nle-069628	Nomascus leucogenys	39.46	0.00e+00	1404.00
IUUC-Opr-070242	Ochotona princeps	37.96	0.00e+00	979.00
IUUC-Oan-073598	Ornithorhynchus anatinus	37.83	0.00e+00	1046.00
IUUC-Ocu-073933	Oryctolagus cuniculus	39.64	0.00e+00	1390.00
IUUC-Ola-086886	Oryzias latipes	35.94	0.00e+00	1080.00
IUUC-Oga-088609	Otolemur garnettii	38.71	0.00e+00	1363.00
IUUC-Oar-089957	Ovis aries	38.89	0.00e+00	1322.00
IUUC-Ptr-090577	Pan troglodytes	38.79	0.00e+00	1397.00
IUUC-Pan-092397	Papio anubis	40.05	0.00e+00	1427.00
IUUC-Pma-094373	Petromyzon marinus	33.81	5.00e-77	281.00
IUUC-Pfo-096497	Poecilia formosa	35.85	0.00e+00	1066.00
IUUC-Pab-098028	Pongo abelii	39.42	0.00e+00	1404.00
IUUC-Pca-101002	Procavia capensis	39.20	0.00e+00	784.00
IUUC-Pva-102144	Pteropus vampyrus	39.20	0.00e+00	667.00
IUUC-Rno-105828	Rattus norvegicus	39.64	0.00e+00	1372.00
IUUC-Sha-106469	Sarcophilus harrisii	39.93	0.00e+00	1415.00
IUUC-Sar-113035	Sorex araneus	37.61	2.00e-170	593.00
IUUC-Ssc-116122	Sus scrofa	38.76	0.00e+00	991.00
IUUC-Tru-118412	Takifugu rubripes	34.57	0.00e+00	1111.00
IUUC-Tsy-119257	Tarsius syrichta	37.32	4.00e-136	480.00
IUUC-Tni-120032	Tetraodon nigroviridis	34.07	9.00e-43	167.00
IUUC-Tbe-127312	Tupaia belangeri	35.48	6.00e-105	376.00
IUUC-Ttr-128335	Tursiops truncatus	38.30	0.00e+00	1226.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence