iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-028208

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

TNF receptor-associated factor 3

Genbank Nucleotide ID

BX511189

Gene Name

traf3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000022000.9	ENSDART00000031458.7	ENSDARP00000038596.7

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	55.23	1.00e-175	614.00	IUUC-Hsa-046957

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Danio rerio

Protein Sequence
(Fasta)

MSAGRNVEQQ IPLQQRPPSL AMPSMAQRPR PEPGFSPLHG GFRDHFVTTP EPKYCCETCR 60
LVLCNPRQTE CGHRFCESCI NELLSKPNPV CPADLLPLFE DKIFRDVCCN REIMALKVYC 120

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Nucleotide Sequence
(Fasta)

GGCTTCTCTA CCTTTTCGTG CACCTCAACC GAGCCCATTT CAGAACATTC CGATGTCAAA 60
ATGACCCGAT TTGATCCGAC GGCCGTTGTA GCCTGTTTGA GAAGCGAGGA CGCAGCCGTG 120

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Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0675--Receptor
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027128--TRAF3
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF00097--zf-C3HC4
PF02176--zf-TRAF

SMART

SM00061--MATH
SM00184--RING

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0042981--P:regulation of apoptotic process
GO:0001817--P:regulation of cytokine production
GO:0050688--P:regulation of defense response to virus
GO:0001878--P:response to yeast
GO:0008063--P:Toll signaling pathway
GO:0033209--P:tumor necrosis factor-mediated signaling pathway

KEGG

dre:445119

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002362	Ailuropoda melanoleuca	56.58	0.00e+00	670.00
IUUC-Apl-004189	Anas platyrhynchos	56.41	0.00e+00	686.00
IUUC-Aca-004540	Anolis carolinensis	56.05	0.00e+00	669.00
IUUC-Ame-010645	Astyanax mexicanus	83.33	0.00e+00	952.00
IUUC-Bgr-012191	Blumeria graminis	27.73	3.00e-15	77.00
IUUC-Bta-013140	Bos taurus	55.95	0.00e+00	667.00
IUUC-Bci-013998	Botrytis cinerea	24.51	2.00e-15	77.40
IUUC-Cja-019436	Callithrix jacchus	55.57	0.00e+00	671.00
IUUC-Cfa-021072	Canis familiaris	55.40	0.00e+00	670.00
IUUC-Cpo-022472	Cavia porcellus	55.40	0.00e+00	672.00
IUUC-Csa-024217	Chlorocebus sabaeus	56.10	0.00e+00	680.00
IUUC-Cho-025066	Choloepus hoffmanni	47.18	8.00e-133	467.00
IUUC-Cin-025234	Ciona intestinalis	28.04	3.00e-52	199.00
IUUC-Csv-026078	Ciona savignyi	65.34	4.00e-75	273.00
IUUC-Dno-028868	Dasypus novemcinctus	55.75	0.00e+00	674.00
IUUC-Dor-031056	Dipodomys ordii	57.61	2.00e-172	598.00
IUUC-Ete-033005	Echinops telfairi	48.91	5.00e-129	454.00
IUUC-Eca-033717	Equus caballus	55.75	0.00e+00	672.00
IUUC-Eeu-035172	Erinaceus europaeus	38.25	3.00e-69	256.00
IUUC-Fca-035688	Felis catus	55.65	0.00e+00	667.00
IUUC-Fal-037176	Ficedula albicollis	56.41	0.00e+00	687.00
IUUC-Gmo-038931	Gadus morhua	70.50	0.00e+00	726.00
IUUC-Gga-040519	Gallus gallus	40.86	4.00e-119	421.00
IUUC-Gac-042019	Gasterosteus aculeatus	74.52	0.00e+00	834.00
IUUC-Ggo-044424	Gorilla gorilla	55.92	0.00e+00	674.00
IUUC-Hsa-046957	Homo sapiens	55.75	0.00e+00	671.00
IUUC-Itr-048352	Ictidomys tridecemlineatus	56.27	0.00e+00	680.00
IUUC-Lch-050680	Latimeria chalumnae	57.04	0.00e+00	651.00
IUUC-Loc-052093	Lepisosteus oculatus	73.83	0.00e+00	902.00
IUUC-Lma-053014	Leptosphaeria maculans	27.31	4.00e-15	76.60
IUUC-Laf-054573	Loxodonta africana	55.34	0.00e+00	633.00
IUUC-Mcc-055049	Macaca mulatta	56.10	0.00e+00	675.00
IUUC-Mga-059244	Meleagris gallopavo	56.41	0.00e+00	688.00
IUUC-Mmr-061469	Microcebus murinus	55.92	0.00e+00	677.00
IUUC-Mdo-063049	Monodelphis domestica	55.95	0.00e+00	675.00
IUUC-Mmu-063763	Mus musculus	55.92	0.00e+00	674.00
IUUC-Mpu-065956	Mustela putorius furo	57.96	0.00e+00	667.00
IUUC-Mlu-067482	Myotis lucifugus	55.71	0.00e+00	658.00
IUUC-Nfi-068511	Neosartorya fischeri	24.28	2.00e-16	80.50
IUUC-Nle-069941	Nomascus leucogenys	56.10	0.00e+00	677.00
IUUC-Opr-071027	Ochotona princeps	50.78	1.00e-165	577.00
IUUC-Ont-071914	Oreochromis niloticus	74.49	0.00e+00	910.00
IUUC-Oan-072802	Ornithorhynchus anatinus	56.58	0.00e+00	680.00
IUUC-Ocu-074075	Oryctolagus cuniculus	55.75	0.00e+00	671.00
IUUC-Ola-086783	Oryzias latipes	35.30	3.00e-96	346.00
IUUC-Oga-088149	Otolemur garnettii	55.57	0.00e+00	673.00
IUUC-Oar-089922	Ovis aries	52.23	6.00e-178	617.00
IUUC-Ptr-091412	Pan troglodytes	55.75	0.00e+00	672.00
IUUC-Pan-092789	Papio anubis	56.10	0.00e+00	680.00
IUUC-Psi-093603	Pelodiscus sinensis	57.40	0.00e+00	690.00
IUUC-Pma-094463	Petromyzon marinus	48.44	3.00e-140	491.00
IUUC-Pno-094854	Phaeosphaeria nodorum	26.75	6.00e-13	68.90
IUUC-Pfo-096518	Poecilia formosa	72.01	0.00e+00	873.00
IUUC-Pab-097664	Pongo abelii	55.92	0.00e+00	674.00
IUUC-Pca-100821	Procavia capensis	53.80	1.00e-155	542.00
IUUC-Pva-102112	Pteropus vampyrus	41.23	6.00e-122	431.00
IUUC-Pte-104279	Pyrenophora teres	28.69	2.00e-16	81.60
IUUC-Pyt-104429	Pyrenophora triticirepentis	28.69	1.00e-15	78.20
IUUC-Rno-105505	Rattus norvegicus	56.63	0.00e+00	669.00
IUUC-Sha-107416	Sarcophilus harrisii	56.05	0.00e+00	677.00
IUUC-Ssl-108580	Sclerotinia sclerotiorum	25.61	3.00e-14	73.20
IUUC-Ssc-115351	Sus scrofa	55.75	0.00e+00	671.00
IUUC-Tgu-116608	Taeniopygia guttata	57.78	0.00e+00	683.00
IUUC-Tru-117964	Takifugu rubripes	75.17	0.00e+00	851.00
IUUC-Tsy-119571	Tarsius syrichta	38.30	4.00e-105	375.00
IUUC-Tni-120211	Tetraodon nigroviridis	76.48	0.00e+00	854.00
IUUC-Tbe-127412	Tupaia belangeri	41.10	5.00e-110	391.00
IUUC-Vpa-130074	Vicugna pacos	58.28	1.00e-156	546.00
IUUC-Xtr-132563	Xenopus tropicalis	53.83	0.00e+00	657.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence