iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053499

UUCD1 version

UUC-LoA-00541

Ensembl Protein ID

ENSLAFP00000012953.3

UniProt Accession

G3TF71; G3TF71_LOXAF

Protein Name

Uncharacterized protein

Gene Name

TRAF7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000015455.3	ENSLAFT00000015457.3	ENSLAFP00000012953.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-31	107.2	326	357
UBD/Beta-Prp	3.40e-49	168.0	326	602

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           gH+++v+cl+  s+ +ll sGs D+tikvWD+
   Q: 326  GHQGPVWCLCVySTgDLLFSGSSDKTIKVWDT 357
           8*********77667****************6 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdv.ttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghe 94
           gh+  ++ c+++   ++ll++gs d+tikvwd+ tt k+ ++l+gh++ v a++++     l +gs D ti vwd+++ + v t+++h+
   Q: 326  GHQG-PVWCLCVYSTGDLLFSGSSDKTIKVWDTcTTYKCQKTLEGHDGIVLALCIQGC--KLYSGSADCTIIVWDIQNLQKVNTIRAHD 411
           5555.55569999*******************846678899***************99..6**************************** PP
   S: 95   dsvlslsfspsgdklvsGshdrtirvwdl.etgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtds 182
           + v++l +s   + l sGs  + i+vwd+  t+ +l++ l+g +++v+ +v  +  ++l sGs+ +t+++Wd++t ++++ l+    +s
   Q: 412  NPVCTLVSSH--NMLFSGS-LKAIKVWDIvGTELKLKKELTGLNHWVRALVAAQ--SYLYSGSY-QTIKIWDIRTLDCIHVLQT-SGGS 493
           *****99999..9******.9*******7368888888**************99..*******9.79***************99.**** PP
   S: 183  vyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfs..pnderlvsgssDgsiriWdlrsgdllktlqlhnssvis 269
           vys++++s   ++v g + + + +wd++++e vrtl+gh  +v+ +++   p+++ + s+s D+s+r+W +++  +++tl +h+ sv++
   Q: 494  VYSIAVTS--HHIVCGTYENLIHVWDIESKEQVRTLTGHVGTVYALAVIstPDQTKVFSASYDRSLRVWSMDNMICTQTLLRHQGSVTA 580
           ********..8***********************************99888************************************** PP
   S: 270  vavlsfgdnvlvlgsedskvniwkl 294
            av   ++  l++g+ ds+v++w +
   Q: 581  LAV---SRGRLFSGAVDSTVKVWTC 602
           **9...*****************86 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

TRMETTFGPA FSAVTTVTKA DGTSTYKQHR RTPSSSSTLA YSPRDEEDSM EPLVFAEQPS 60
VKLCCQLCCC VFKDPVITTC GHTFCRRCAL KSEKCPVDSA KLTVVVNNIA VAEQVGELFI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCAGGATGG AAACAACCTT CGGGCCTGCC TTTTCAGCCG TCACCACCGT CACGAAAGGT 60
GAGCCTCTGA GGGCCTGGCC GATTCTGGGC ACAGGGTCTG CTTCCTCCTC CCTGGCCATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR008974--TRAF-like
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00184--RING
SM00320--WD40

Gene Ontology

GO:0043231--C:intracellular membrane-bounded organelle
GO:0005886--C:plasma membrane
GO:0000151--C:ubiquitin ligase complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0000185--P:activation of MAPKKK activity
GO:0006915--P:apoptotic process
GO:2001235--P:positive regulation of apoptotic signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001971	Ailuropoda melanoleuca	90.85	0.00e+00	1169.00
IUUC-Apl-004098	Anas platyrhynchos	88.61	0.00e+00	1113.00
IUUC-Aca-004852	Anolis carolinensis	82.91	0.00e+00	865.00
IUUC-Ame-011275	Astyanax mexicanus	76.83	0.00e+00	846.00
IUUC-Bta-013153	Bos taurus	90.98	0.00e+00	1167.00
IUUC-Cja-019243	Callithrix jacchus	90.27	0.00e+00	1127.00
IUUC-Cfa-020036	Canis familiaris	91.45	0.00e+00	1177.00
IUUC-Cpo-022194	Cavia porcellus	91.09	0.00e+00	1168.00
IUUC-Csa-023363	Chlorocebus sabaeus	90.98	0.00e+00	1170.00
IUUC-Cin-025279	Ciona intestinalis	57.34	0.00e+00	775.00
IUUC-Csv-026163	Ciona savignyi	64.07	0.00e+00	760.00
IUUC-Dre-027998	Danio rerio	83.62	0.00e+00	1042.00
IUUC-Dno-029356	Dasypus novemcinctus	93.75	1.00e-125	441.00
IUUC-Dor-030750	Dipodomys ordii	89.42	0.00e+00	1142.00
IUUC-Eca-033671	Equus caballus	76.43	0.00e+00	910.00
IUUC-Eeu-034765	Erinaceus europaeus	97.70	2.00e-165	575.00
IUUC-Fca-035843	Felis catus	91.29	0.00e+00	1178.00
IUUC-Fal-037237	Ficedula albicollis	88.65	0.00e+00	1121.00
IUUC-Gmo-038779	Gadus morhua	75.70	0.00e+00	942.00
IUUC-Gga-040579	Gallus gallus	88.34	0.00e+00	1117.00
IUUC-Gac-042233	Gasterosteus aculeatus	81.07	0.00e+00	1046.00
IUUC-Ggo-045147	Gorilla gorilla	90.67	0.00e+00	1167.00
IUUC-Hsa-046117	Homo sapiens	90.82	0.00e+00	1169.00
IUUC-Itr-048899	Ictidomys tridecemlineatus	91.14	0.00e+00	1176.00
IUUC-Lch-050593	Latimeria chalumnae	86.78	0.00e+00	1073.00
IUUC-Loc-052444	Lepisosteus oculatus	86.78	0.00e+00	1125.00
IUUC-Mcc-055038	Macaca mulatta	91.14	0.00e+00	1171.00
IUUC-Meu-056610	Macropus eugenii	87.55	0.00e+00	857.00
IUUC-Mtr-057641	Medicago truncatula	27.73	1.00e-19	90.90
IUUC-Mga-060183	Meleagris gallopavo	88.22	0.00e+00	1113.00
IUUC-Mmr-061133	Microcebus murinus	88.89	0.00e+00	1098.00
IUUC-Mdo-062312	Monodelphis domestica	89.91	0.00e+00	1161.00
IUUC-Mmu-063844	Mus musculus	90.67	0.00e+00	1142.00
IUUC-Mpu-066552	Mustela putorius furo	91.43	0.00e+00	1168.00
IUUC-Mlu-067719	Myotis lucifugus	90.82	0.00e+00	1140.00
IUUC-Nle-070045	Nomascus leucogenys	90.24	0.00e+00	1129.00
IUUC-Opr-070927	Ochotona princeps	89.11	0.00e+00	1144.00
IUUC-Ont-072680	Oreochromis niloticus	81.86	0.00e+00	1057.00
IUUC-Oan-073521	Ornithorhynchus anatinus	93.00	1.00e-51	193.00
IUUC-Ogu-077987	Oryza glumaepatula	25.86	1.00e-18	87.40
IUUC-Ola-087454	Oryzias latipes	83.51	0.00e+00	1099.00
IUUC-Oga-088380	Otolemur garnettii	90.82	0.00e+00	1172.00
IUUC-Oar-089558	Ovis aries	80.03	0.00e+00	965.00
IUUC-Ptr-091606	Pan troglodytes	90.67	0.00e+00	1167.00
IUUC-Pan-092227	Papio anubis	91.14	0.00e+00	1171.00
IUUC-Psi-093853	Pelodiscus sinensis	80.53	0.00e+00	930.00
IUUC-Pma-094541	Petromyzon marinus	81.01	3.00e-152	530.00
IUUC-Pfo-096237	Poecilia formosa	82.33	0.00e+00	1054.00
IUUC-Pab-097589	Pongo abelii	90.82	0.00e+00	1170.00
IUUC-Pca-100375	Procavia capensis	90.92	0.00e+00	1139.00
IUUC-Pva-102434	Pteropus vampyrus	91.14	0.00e+00	1175.00
IUUC-Rno-105443	Rattus norvegicus	90.82	0.00e+00	1145.00
IUUC-Sha-106517	Sarcophilus harrisii	89.61	0.00e+00	1155.00
IUUC-Ssc-115990	Sus scrofa	90.67	0.00e+00	1164.00
IUUC-Tgu-117222	Taeniopygia guttata	88.44	0.00e+00	1111.00
IUUC-Tru-118392	Takifugu rubripes	82.04	0.00e+00	1068.00
IUUC-Tni-120220	Tetraodon nigroviridis	81.61	0.00e+00	1055.00
IUUC-Tbe-128045	Tupaia belangeri	98.61	9.00e-160	556.00
IUUC-Ttr-128203	Tursiops truncatus	87.40	0.00e+00	1109.00
IUUC-Xtr-132043	Xenopus tropicalis	87.40	0.00e+00	1133.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence