iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052444

Ensembl Protein ID

ENSLOCP00000006903.1

UniProt Accession

W5MEU4; W5MEU4_LEPOC

Genbank Protein ID

ENSLOCP00000006903

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01013554

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000005718.1	ENSLOCT00000006911.1	ENSLOCP00000006903.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.30e-33	111.0	399	430
UBD/Beta-Prp	7.10e-49	166.7	397	675

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           gH+++v+cl+  s+ +ll sGs D+tikvWD+
   Q: 399  GHQGPVWCLCVySTgDLLFSGSSDKTIKVWDT 430
           8*********77667****************6 PP

UBD/Beta-Prp

   S: 5    lkghhksvitcvkfspdksllatgsrdgtikvwdv.ttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkg 92
           + gh+  v+ c+++   ++ll++gs d+tikvwd+ tt k+ ++l+gh++ v a++++ +   l +gs D ti vwd++t + v t+++
   Q: 397  FVGHQGPVW-CLCVYSTGDLLFSGSSDKTIKVWDTcTTYKCQKTLEGHDGIVLALCIQGN--KLYSGSADCTIIVWDIQTLQKVNTIRA 482
           556666555.59999*******************846678899****************9..6************************** PP
   S: 93   hedsvlslsfspsgdklvsGshdrtirvwdl.etgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgght 180
           h++ v++l +s   + l sGs  + i+vwd+  t+ +l++ l+g +++v+ +v ++  n l sGs+ +t+++Wd+++ ++++ l+    
   Q: 483  HDNPVCTLVSSH--NMLFSGS-LKAIKVWDIvGTELKLKKELTGLNHWVRALVASQ--NHLYSGSY-QTIKIWDIRSLECVHVLQT-SG 564
           *******99999..9******.9*******7368888888**************99..99*****9.79***************99.** PP
   S: 181  dsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfs..pnderlvsgssDgsiriWdlrsgdllktlqlhnssv 267
           +svys++++    ++v g + + + +wd++++e vrtl+gh  +v+ +++   p+++ + s+s D+s+r+W +++  +++tl +h+ sv
   Q: 565  GSVYSIAVTN--HHIVCGTYENLIHVWDIESKEQVRTLTGHVGTVYALAVIstPDQTKVFSASYDRSLRVWSMDNMICTQTLLRHQGSV 651
           *********9..8***********************************99888************************************ PP
   S: 268  isvavlsfgdnvlvlgsedskvniwkl 294
           ++ av   ++  l++g+ ds+v++w +
   Q: 652  TALAV---SRGRLFSGAVDSTVKVWTC 675
           ****9...*****************86 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MSSSKTLRYN RFSGGAAAVV ASVPPADTAN TQTRMETTFG PAYATVTTIT KAEGSTNYKQ 60
HRRTPSSSSS MTYSPRDEDD GMPPISTPRR SDSAISVRSL HSESTMSLRS TFSLHEEEED 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTGCAACTG TCAGGTCCAG GGAGGCTGTG CTGGACTATG AGCTCCAGTA AGACTCTGCG 60
CTACAACCGT TTTTCTGGAG GTGCTGCAGC AGTCGTGGCC AGTGTCCCAC CTGCCGACAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0853--WD repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR020472--G-protein_beta_WD-40_rep
IPR008974--TRAF-like
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF00400--WD40
PF13445--zf-RING_UBOX

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00184--RING
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001971	Ailuropoda melanoleuca	89.82	0.00e+00	1186.00
IUUC-Apl-004098	Anas platyrhynchos	95.16	0.00e+00	1211.00
IUUC-Aca-004852	Anolis carolinensis	87.76	0.00e+00	982.00
IUUC-Ame-011275	Astyanax mexicanus	86.68	0.00e+00	1002.00
IUUC-Bta-013153	Bos taurus	90.81	0.00e+00	1197.00
IUUC-Cja-019243	Callithrix jacchus	88.92	0.00e+00	1145.00
IUUC-Cfa-020036	Canis familiaris	90.96	0.00e+00	1201.00
IUUC-Cpo-022194	Cavia porcellus	90.33	0.00e+00	1191.00
IUUC-Csa-023363	Chlorocebus sabaeus	90.22	0.00e+00	1194.00
IUUC-Cin-025279	Ciona intestinalis	59.29	0.00e+00	807.00
IUUC-Csv-026163	Ciona savignyi	63.52	0.00e+00	767.00
IUUC-Dre-027998	Danio rerio	94.85	0.00e+00	1184.00
IUUC-Dno-029356	Dasypus novemcinctus	90.18	7.00e-124	436.00
IUUC-Dor-030750	Dipodomys ordii	88.30	0.00e+00	1153.00
IUUC-Eca-033671	Equus caballus	76.36	0.00e+00	920.00
IUUC-Eeu-034765	Erinaceus europaeus	94.74	3.00e-161	561.00
IUUC-Fca-035843	Felis catus	90.96	0.00e+00	1204.00
IUUC-Fal-037237	Ficedula albicollis	92.60	0.00e+00	1234.00
IUUC-Gmo-038779	Gadus morhua	84.27	0.00e+00	1062.00
IUUC-Gga-040579	Gallus gallus	92.31	0.00e+00	1233.00
IUUC-Gac-042233	Gasterosteus aculeatus	89.18	0.00e+00	1172.00
IUUC-Gma-042914	Glycine max	30.04	8.00e-20	91.30
IUUC-Ggo-045147	Gorilla gorilla	90.22	0.00e+00	1193.00
IUUC-Hsa-046117	Homo sapiens	90.22	0.00e+00	1194.00
IUUC-Itr-048899	Ictidomys tridecemlineatus	90.67	0.00e+00	1202.00
IUUC-Lch-050593	Latimeria chalumnae	92.00	0.00e+00	1212.00
IUUC-Laf-053499	Loxodonta africana	86.94	0.00e+00	1130.00
IUUC-Mcc-055038	Macaca mulatta	90.37	0.00e+00	1196.00
IUUC-Meu-056610	Macropus eugenii	88.74	0.00e+00	894.00
IUUC-Mtr-057641	Medicago truncatula	28.02	1.00e-20	94.40
IUUC-Mga-060183	Meleagris gallopavo	91.89	0.00e+00	1224.00
IUUC-Mmr-061133	Microcebus murinus	88.36	0.00e+00	1121.00
IUUC-Mdo-062312	Monodelphis domestica	91.72	0.00e+00	1214.00
IUUC-Mmu-063844	Mus musculus	90.52	0.00e+00	1172.00
IUUC-Mpu-066552	Mustela putorius furo	90.81	0.00e+00	1190.00
IUUC-Mlu-067719	Myotis lucifugus	89.78	0.00e+00	1160.00
IUUC-Nle-070045	Nomascus leucogenys	92.96	0.00e+00	1140.00
IUUC-Opr-070927	Ochotona princeps	88.89	0.00e+00	1164.00
IUUC-Ont-072680	Oreochromis niloticus	89.06	0.00e+00	1204.00
IUUC-Oan-073521	Ornithorhynchus anatinus	95.00	9.00e-53	197.00
IUUC-Ola-087454	Oryzias latipes	92.82	0.00e+00	1241.00
IUUC-Oga-088380	Otolemur garnettii	90.52	0.00e+00	1197.00
IUUC-Oar-089558	Ovis aries	74.38	0.00e+00	942.00
IUUC-Ptr-091606	Pan troglodytes	90.22	0.00e+00	1193.00
IUUC-Pan-092227	Papio anubis	90.37	0.00e+00	1196.00
IUUC-Psi-093853	Pelodiscus sinensis	85.78	0.00e+00	1019.00
IUUC-Pma-094541	Petromyzon marinus	81.65	7.00e-156	542.00
IUUC-Pfo-096237	Poecilia formosa	89.45	0.00e+00	1201.00
IUUC-Pab-097589	Pongo abelii	90.37	0.00e+00	1195.00
IUUC-Pca-100375	Procavia capensis	91.55	0.00e+00	1135.00
IUUC-Pva-102434	Pteropus vampyrus	90.52	0.00e+00	1195.00
IUUC-Rno-105443	Rattus norvegicus	90.81	0.00e+00	1180.00
IUUC-Sha-106517	Sarcophilus harrisii	91.43	0.00e+00	1208.00
IUUC-Sly-111122	Solanum lycopersicum	27.27	1.00e-17	84.30
IUUC-Ssc-115990	Sus scrofa	90.52	0.00e+00	1198.00
IUUC-Tgu-117222	Taeniopygia guttata	92.26	0.00e+00	1220.00
IUUC-Tru-118392	Takifugu rubripes	92.54	0.00e+00	1207.00
IUUC-Tni-120220	Tetraodon nigroviridis	91.64	0.00e+00	1191.00
IUUC-Tbe-128045	Tupaia belangeri	96.88	4.00e-158	551.00
IUUC-Ttr-128203	Tursiops truncatus	87.26	0.00e+00	1141.00
IUUC-Xtr-132043	Xenopus tropicalis	90.24	0.00e+00	1243.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence