iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSG00000132017.10	ENST00000254337.10	ENSP00000254337.5
ENSG00000132017.10	ENST00000591802.1	ENSP00000466932.1
ENSG00000132017.10	ENST00000585468.1	ENSP00000466048.1
ENSG00000132017.10	ENST00000587307.1	ENSP00000468330.1

Annotation

Cancer Mutation
TCGA	ICGC	COSMIC	CGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	TCGA	ICGC
COSMIC	HPM
DNA & RNA Element
AREsite	circBase	circRNADb	CircNet
miRTarBase	microRNA	TRANSFAC	TargetScan
miRNAMap	SomamiR	miRcode	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	HINT
Mentha	InWeb_IM
Post-translational Modifications (PTMs)
CPLM	dbPAF	PhosphositePlus	dbPTM
HPRD	UniProt
DNA Methylation
TCGA	ICGC
Protein Expression/Proteomics
THPA	HPM	GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 adaptor/Cullin RING/Other	E3 adaptor/Cullin RING/Other	17588513

Organism

Homo sapiens

Functional Description
(View)

May be involved in ubiquitination and degradation through a DBB1-CUL4 E3 protein-ubiquitin ligase.

Protein Sequence
(Fasta)

MAPSSKSERN SGAGSGGGGP GGAGGKRAAG RRREHVLKQL ERVKISGQLS PRLFRKLPPR 60
VCVSLKNIVD EDFLYAGHIF LGFSKCGRYV LSYTSSSGDD DFSFYIYHLY WWEFNVHSKL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGTGGAGGG AGGGGGTGAA AATGGCGCCC AGCTCGAAAT CGGAGCGGAA CAGCGGGGCT 60
GGGAGCGGCG GCGGCGGCCC CGGGGGAGCC GGAGGGAAGC GGGCAGCAGG GCGGCGGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032734--DCAF15_WD40

Pfam

PF14939--DCAF15_WD40

Gene Ontology

GO:0016567--P:protein ubiquitination

KEGG

hsa:90379

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000521	Aegilops tauschii	35.53	1.30e-02	32.70
IUUC-Aml-002131	Ailuropoda melanoleuca	87.67	0.00e+00	941.00
IUUC-Aca-004425	Anolis carolinensis	78.48	0.00e+00	855.00
IUUC-Ame-010683	Astyanax mexicanus	51.69	2.00e-85	310.00
IUUC-Bta-013021	Bos taurus	94.00	0.00e+00	970.00
IUUC-Cja-019025	Callithrix jacchus	96.01	0.00e+00	1009.00
IUUC-Cfa-021084	Canis familiaris	93.83	0.00e+00	954.00
IUUC-Cpo-022121	Cavia porcellus	87.99	0.00e+00	963.00
IUUC-Csa-023948	Chlorocebus sabaeus	99.00	0.00e+00	1041.00
IUUC-Csv-026291	Ciona savignyi	33.33	1.00e-04	39.70
IUUC-Dre-027564	Danio rerio	52.23	2.00e-86	313.00
IUUC-Dno-029359	Dasypus novemcinctus	78.26	8.00e-123	434.00
IUUC-Dor-030575	Dipodomys ordii	93.64	5.00e-93	335.00
IUUC-Dme-031812	Drosophila melanogaster	28.37	4.00e-17	83.60
IUUC-Eca-033841	Equus caballus	96.80	2.00e-122	431.00
IUUC-Fca-035959	Felis catus	87.97	0.00e+00	902.00
IUUC-Gmo-038516	Gadus morhua	66.52	6.00e-78	283.00
IUUC-Gac-042050	Gasterosteus aculeatus	68.49	6.00e-82	296.00
IUUC-Ggo-045260	Gorilla gorilla	98.83	0.00e+00	1050.00
IUUC-Itr-048867	Ictidomys tridecemlineatus	90.37	0.00e+00	961.00
IUUC-Lch-050379	Latimeria chalumnae	61.89	0.00e+00	697.00
IUUC-Loc-051842	Lepisosteus oculatus	73.18	5.00e-91	328.00
IUUC-Laf-054400	Loxodonta africana	94.00	0.00e+00	1012.00
IUUC-Mcc-055062	Macaca mulatta	99.00	0.00e+00	1041.00
IUUC-Meu-056876	Macropus eugenii	74.43	3.00e-157	548.00
IUUC-Mmr-060633	Microcebus murinus	95.17	0.00e+00	969.00
IUUC-Mdo-062764	Monodelphis domestica	86.42	0.00e+00	954.00
IUUC-Mmu-063100	Mus musculus	90.83	0.00e+00	994.00
IUUC-Mpu-065728	Mustela putorius furo	92.45	0.00e+00	808.00
IUUC-Mlu-067708	Myotis lucifugus	92.33	0.00e+00	999.00
IUUC-Nle-069658	Nomascus leucogenys	97.50	0.00e+00	1030.00
IUUC-Ont-071897	Oreochromis niloticus	58.25	0.00e+00	641.00
IUUC-Oan-073234	Ornithorhynchus anatinus	70.66	0.00e+00	776.00
IUUC-Ola-087374	Oryzias latipes	53.64	2.00e-176	612.00
IUUC-Olu-087592	Ostreococcus lucimarinus	28.12	6.00e-08	52.40
IUUC-Oga-088209	Otolemur garnettii	94.00	0.00e+00	1007.00
IUUC-Oar-090064	Ovis aries	89.59	0.00e+00	966.00
IUUC-Ptr-090570	Pan troglodytes	99.17	0.00e+00	857.00
IUUC-Pan-092893	Papio anubis	99.00	0.00e+00	1041.00
IUUC-Psi-093125	Pelodiscus sinensis	63.35	5.00e-150	524.00
IUUC-Pma-094436	Petromyzon marinus	44.70	1.00e-52	199.00
IUUC-Pfo-096372	Poecilia formosa	53.82	4.00e-169	588.00
IUUC-Pab-097558	Pongo abelii	85.83	0.00e+00	850.00
IUUC-Pca-101103	Procavia capensis	92.01	0.00e+00	984.00
IUUC-Pva-102737	Pteropus vampyrus	93.68	0.00e+00	1011.00
IUUC-Rno-105426	Rattus norvegicus	89.50	0.00e+00	999.00
IUUC-Sha-107473	Sarcophilus harrisii	84.00	0.00e+00	922.00
IUUC-Stu-112391	Solanum tuberosum	30.61	2.60e-02	32.70
IUUC-Sar-113588	Sorex araneus	75.71	3.00e-124	438.00
IUUC-Ssc-115806	Sus scrofa	93.83	0.00e+00	1011.00
IUUC-Tru-118055	Takifugu rubripes	55.13	3.00e-173	602.00
IUUC-Tni-119789	Tetraodon nigroviridis	58.16	1.00e-171	596.00
IUUC-Ttr-128380	Tursiops truncatus	91.33	0.00e+00	976.00
IUUC-Vda-129995	Verticillium dahliae	30.00	4.00e-03	36.20
IUUC-Xtr-132715	Xenopus tropicalis	65.56	0.00e+00	701.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence