iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
CPLM	dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/VHS	2.80e-55	186.3	16	143
UBD/SH3	4.60e-17	62.1	213	265

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/VHS

   S: 1    atselvtsedwelileicdliqetkegakdalralrkrinnknphvalraLtlLdscvsnCgkkfhvevaskdlleelrellknenepk 89
           atsel+t+edw lil+icd+++++++g+kd+lr++++r+n+k+phva++aLtlL++cvsnCgk+fh+ev+s+d+++e++++l n+ +pk
   Q: 16   ATSELNTAEDWGLILDICDKVGQSRTGPKDCLRSIMRRVNHKDPHVAMQALTLLGACVSNCGKIFHLEVCSRDFASEVSNVL-NKGHPK 103
           799*******************************************************************************.9***** PP
   S: 90   vieKlkalivsWadelknepalslivaliktlkeeGlefp 129
           v+eKlkal+v+W+de+kn+p+lsli+a+ik+lke+G++fp
   Q: 104  VCEKLKALMVEWTDEFKNDPQLSLISAMIKNLKEQGVTFP 143
           ***************************************8 PP

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           +kv++ yd+ea++d+eLt+k+G+v++v+  ++ d +W+kg  e+++  GlfP+nFv+
   Q: 213  RKVRAVYDFEAAEDNELTFKAGEVITVL--DDSDPNWWKG--ETHQGMGLFPSNFVT 265
           689*************************..99********..9************97 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MPLFATNPFD QDVEKATSEL NTAEDWGLIL DICDKVGQSR TGPKDCLRSI MRRVNHKDPH 60
VAMQALTLLG ACVSNCGKIF HLEVCSRDFA SEVSNVLNKG HPKVCEKLKA LMVEWTDEFK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTGCACTGG CAATCTCCCT TAGTGTTTTT GTACCTGAGG GGCCTCCTTT CTCCGTCACT 60
TCTCGAGTGC CGCGGTGTCG AGGGGCAGTC CCTGGGGACA CCTCGGCACG CAGCGGACAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR008942--ENTH_VHS
IPR004152--GAT_dom
IPR001452--SH3_domain
IPR003903--UIM_dom
IPR002014--VHS_dom

PROSITE

PS50002--SH3
PS50330--UIM
PS50179--VHS

Pfam

PF00018--SH3_1
PF02809--UIM
PF00790--VHS

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3
SM00288--VHS

Gene Ontology

GO:0005622--C:intracellular
GO:0006886--P:intracellular protein transport
GO:1903543--P:positive regulation of exosomal secretion
GO:1903551--P:regulation of extracellular exosome assembly

KEGG

rno:498798

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002392	Ailuropoda melanoleuca	89.52	0.00e+00	895.00
IUUC-Apl-003463	Anas platyrhynchos	83.20	0.00e+00	845.00
IUUC-Aca-005116	Anolis carolinensis	78.80	0.00e+00	818.00
IUUC-Afl-008621	Aspergillus flavus	26.95	5.00e-35	142.00
IUUC-Afu-008826	Aspergillus fumigatus	29.39	2.00e-29	124.00
IUUC-Ang-009580	Aspergillus niger	28.61	7.00e-37	148.00
IUUC-Ame-011220	Astyanax mexicanus	79.47	0.00e+00	726.00
IUUC-Bta-013368	Bos taurus	88.34	0.00e+00	872.00
IUUC-Cel-018461	Caenorhabditis elegans	32.80	2.00e-51	196.00
IUUC-Cja-019133	Callithrix jacchus	88.53	0.00e+00	872.00
IUUC-Cfa-020800	Canis familiaris	89.33	0.00e+00	893.00
IUUC-Cpo-021685	Cavia porcellus	88.54	0.00e+00	884.00
IUUC-Csa-023325	Chlorocebus sabaeus	89.14	0.00e+00	884.00
IUUC-Cho-024556	Choloepus hoffmanni	85.56	0.00e+00	760.00
IUUC-Cin-025766	Ciona intestinalis	39.47	4.00e-52	197.00
IUUC-Csv-026035	Ciona savignyi	40.52	7.00e-48	183.00
IUUC-Cgl-026648	Colletotrichum gloeosporioides	27.07	1.00e-39	158.00
IUUC-Dre-028379	Danio rerio	69.69	0.00e+00	733.00
IUUC-Dno-029288	Dasypus novemcinctus	83.59	0.00e+00	837.00
IUUC-Dor-030515	Dipodomys ordii	82.67	0.00e+00	750.00
IUUC-Dme-031987	Drosophila melanogaster	44.93	3.00e-98	352.00
IUUC-Ete-032804	Echinops telfairi	74.19	0.00e+00	674.00
IUUC-Eca-033520	Equus caballus	88.84	0.00e+00	839.00
IUUC-Eeu-034820	Erinaceus europaeus	86.47	0.00e+00	802.00
IUUC-Fca-035914	Felis catus	89.64	0.00e+00	894.00
IUUC-Fal-037355	Ficedula albicollis	87.07	0.00e+00	805.00
IUUC-Fox-037748	Fusarium oxysporum	30.59	8.00e-39	155.00
IUUC-Fso-038126	Fusarium solani	28.24	2.00e-41	164.00
IUUC-Gmo-039628	Gadus morhua	82.01	0.00e+00	656.00
IUUC-Gga-041110	Gallus gallus	81.69	0.00e+00	878.00
IUUC-Gac-042301	Gasterosteus aculeatus	78.00	0.00e+00	716.00
IUUC-Ggo-044963	Gorilla gorilla	89.52	0.00e+00	885.00
IUUC-Hsa-046159	Homo sapiens	89.71	0.00e+00	885.00
IUUC-Itr-048016	Ictidomys tridecemlineatus	86.09	5.00e-179	620.00
IUUC-Kpa-049200	Komagataella pastoris	24.29	3.00e-26	112.00
IUUC-Lch-050447	Latimeria chalumnae	76.86	0.00e+00	783.00
IUUC-Loc-052761	Lepisosteus oculatus	75.48	0.00e+00	742.00
IUUC-Lma-053287	Leptosphaeria maculans	27.27	2.00e-36	147.00
IUUC-Laf-053662	Loxodonta africana	88.07	0.00e+00	867.00
IUUC-Mcc-055110	Macaca mulatta	89.14	0.00e+00	882.00
IUUC-Meu-056371	Macropus eugenii	69.98	0.00e+00	668.00
IUUC-Mga-060117	Meleagris gallopavo	81.45	0.00e+00	837.00
IUUC-Mmr-061413	Microcebus murinus	89.71	0.00e+00	865.00
IUUC-Mdo-061951	Monodelphis domestica	87.35	0.00e+00	888.00
IUUC-Mmu-063771	Mus musculus	94.00	0.00e+00	965.00
IUUC-Mpu-066335	Mustela putorius furo	83.63	0.00e+00	796.00
IUUC-Mlu-067740	Myotis lucifugus	88.28	0.00e+00	861.00
IUUC-Nle-069083	Nomascus leucogenys	89.14	0.00e+00	884.00
IUUC-Opr-071162	Ochotona princeps	76.15	2.00e-139	489.00
IUUC-Ont-072360	Oreochromis niloticus	71.59	0.00e+00	731.00
IUUC-Oan-073093	Ornithorhynchus anatinus	81.14	0.00e+00	793.00
IUUC-Ocu-074641	Oryctolagus cuniculus	90.08	0.00e+00	858.00
IUUC-Ola-087487	Oryzias latipes	77.90	0.00e+00	697.00
IUUC-Oga-088551	Otolemur garnettii	88.30	0.00e+00	926.00
IUUC-Oar-089972	Ovis aries	88.15	0.00e+00	873.00
IUUC-Ptr-090672	Pan troglodytes	89.52	0.00e+00	885.00
IUUC-Pan-092407	Papio anubis	91.93	0.00e+00	850.00
IUUC-Psi-092953	Pelodiscus sinensis	81.20	0.00e+00	833.00
IUUC-Pma-094312	Petromyzon marinus	70.74	2.00e-154	538.00
IUUC-Pfo-096030	Poecilia formosa	81.74	0.00e+00	710.00
IUUC-Pab-097691	Pongo abelii	89.33	0.00e+00	884.00
IUUC-Pca-100396	Procavia capensis	77.85	6.00e-179	620.00
IUUC-Pva-103120	Pteropus vampyrus	89.90	0.00e+00	880.00
IUUC-Pgr-103679	Puccinia graminis	39.84	3.00e-20	94.00
IUUC-Ptt-103709	Puccinia triticina	39.84	1.00e-20	94.70
IUUC-Pte-104251	Pyrenophora teres	28.28	2.00e-38	153.00
IUUC-Pyt-104694	Pyrenophora triticirepentis	28.68	8.00e-39	155.00
IUUC-Sha-106927	Sarcophilus harrisii	84.64	0.00e+00	909.00
IUUC-Sar-113551	Sorex araneus	91.65	0.00e+00	837.00
IUUC-Ssc-115322	Sus scrofa	93.30	0.00e+00	776.00
IUUC-Tgu-116550	Taeniopygia guttata	82.86	0.00e+00	867.00
IUUC-Tru-118646	Takifugu rubripes	81.59	0.00e+00	697.00
IUUC-Tsy-118874	Tarsius syrichta	89.14	0.00e+00	869.00
IUUC-Tni-120235	Tetraodon nigroviridis	81.32	0.00e+00	697.00
IUUC-Tre-122061	Trichoderma reesei	27.06	2.00e-34	140.00
IUUC-Tvi-122365	Trichoderma virens	28.68	5.00e-41	162.00
IUUC-Tme-127104	Tuber melanosporum	28.03	5.00e-36	145.00
IUUC-Tbe-127233	Tupaia belangeri	86.85	1.00e-155	543.00
IUUC-Ttr-129298	Tursiops truncatus	82.60	0.00e+00	810.00
IUUC-Vpa-130071	Vicugna pacos	82.32	0.00e+00	774.00
IUUC-Xtr-131863	Xenopus tropicalis	78.11	0.00e+00	757.00
IUUC-Xma-132992	Xiphophorus maculatus	80.55	0.00e+00	720.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence