iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSG00000137073.20	ENST00000379238.5	ENSP00000368540.1
ENSG00000137073.20	ENST00000629575.2	ENSP00000486626.1
ENSG00000137073.20	ENST00000488443.1	ENSP00000433983.1
ENSG00000137073.20	ENST00000412543.5	ENSP00000414800.1
ENSG00000137073.20	ENST00000421278.2	ENSP00000412954.3
ENSG00000137073.20	ENST00000539807.5	ENSP00000439329.2

Annotation

Cancer Mutation
TCGA	ICGC	COSMIC	CGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	TCGA	ICGC
COSMIC	THPA	HPM
DNA & RNA Element
UTRdb	AREsite	circBase	circRNADb
CircNet	miRTarBase	microRNA	TRANSFAC
TargetScan	miRecords	RepTar	miRNAMap
SomamiR	miRcode	RAID2
Protein-protein Interaction
IID	PINA	HINT	Mentha
InWeb_IM
Disease-associated Information
GWASdb
Post-translational Modifications (PTMs)
CPLM	dbPAF	PhosphositePlus	dbPTM
HPRD	Phospho.ELM	UniProt	PHOSIDA
BioGRID	mUbiSiDa
DNA Methylation
TCGA	ICGC	COSMIC
Protein Expression/Proteomics
THPA	HPM	GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
UBD/Alpha-Helix/UBA	UBA	23739027

Classification

Family	E-value	Score	Start	End
UBD/Alpha-Helix/UBA	3.40e-07	31.8	52	92

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlve.MGFdreealqaLraannnleaAveyLldg 41
           ++e k+ ql+e +G +++e++ aL ++n++++ A++ Ll+g
   Q: 52   DFEAKVKQLMEvTGKNQDECIVALHDCNGDVNKAINILLEG 92
           6799***********************************86 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

MMTSVSSDHC RGAREKPQIS AAQSTQPQKQ VVQATAEQMR LAQVIFDKND SDFEAKVKQL 60
MEVTGKNQDE CIVALHDCNG DVNKAINILL EGNSDTTSWE TVGCKKKNFA KENSENKENR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGACGCGAG GTCACGTGAC GGGTTGGGCA GCCTGTGCCG CCGCCGCCGC TTTGTAAGAG 60
GCACATTGGC AGGTAACGAG CGGCGGCGGC GGCAGCGGGT CTTGGGTCCT CCGAGAGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0488--Methylation
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome

Interpro

IPR022166--DUF3697_Uba2
IPR015940--UBA
IPR009060--UBA-like

Pfam

PF12478--DUF3697

SMART

SM00165--UBA

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0045296--F:cadherin binding
GO:0003723--F:RNA binding
GO:0010628--P:positive regulation of gene expression

KEGG

hsa:55833

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001276	Ailuropoda melanoleuca	88.17	0.00e+00	948.00
IUUC-Apl-004228	Anas platyrhynchos	68.91	0.00e+00	677.00
IUUC-Aca-004527	Anolis carolinensis	65.87	0.00e+00	631.00
IUUC-Ath-006826	Arabidopsis thaliana	38.18	1.80e-02	33.10
IUUC-Aor-010169	Aspergillus oryzae	31.58	2.60e-02	34.70
IUUC-Ame-011075	Astyanax mexicanus	68.35	2.00e-95	344.00
IUUC-Bta-013126	Bos taurus	83.27	0.00e+00	1308.00
IUUC-Cel-018655	Caenorhabditis elegans	30.00	2.00e-05	45.10
IUUC-Cja-018765	Callithrix jacchus	93.30	0.00e+00	1443.00
IUUC-Cfa-020094	Canis familiaris	86.49	0.00e+00	1317.00
IUUC-Cpo-022213	Cavia porcellus	66.52	0.00e+00	868.00
IUUC-Csa-023092	Chlorocebus sabaeus	96.13	0.00e+00	986.00
IUUC-Cho-024520	Choloepus hoffmanni	74.38	0.00e+00	721.00
IUUC-Dre-028020	Danio rerio	69.03	6.00e-94	339.00
IUUC-Dno-029541	Dasypus novemcinctus	81.59	0.00e+00	722.00
IUUC-Dor-030998	Dipodomys ordii	83.06	2.00e-142	500.00
IUUC-Dme-031820	Drosophila melanogaster	31.32	8.00e-19	90.10
IUUC-Ete-032440	Echinops telfairi	78.59	4.00e-146	513.00
IUUC-Eca-033886	Equus caballus	86.44	0.00e+00	860.00
IUUC-Eeu-034730	Erinaceus europaeus	72.09	0.00e+00	733.00
IUUC-Fca-035418	Felis catus	87.00	0.00e+00	924.00
IUUC-Fal-037007	Ficedula albicollis	64.66	0.00e+00	629.00
IUUC-Fso-038356	Fusarium solani	28.97	1.50e-02	34.30
IUUC-Gmo-039678	Gadus morhua	58.99	3.00e-65	244.00
IUUC-Gga-040206	Gallus gallus	69.29	0.00e+00	661.00
IUUC-Gac-041513	Gasterosteus aculeatus	42.88	6.00e-77	283.00
IUUC-Ggo-044994	Gorilla gorilla	98.55	0.00e+00	983.00
IUUC-Itr-048760	Ictidomys tridecemlineatus	82.76	0.00e+00	1326.00
IUUC-Lch-049528	Latimeria chalumnae	52.15	2.00e-124	440.00
IUUC-Loc-051733	Lepisosteus oculatus	73.45	4.00e-100	359.00
IUUC-Laf-054430	Loxodonta africana	83.76	0.00e+00	786.00
IUUC-Mcc-055663	Macaca mulatta	96.13	0.00e+00	991.00
IUUC-Meu-056186	Macropus eugenii	65.50	0.00e+00	761.00
IUUC-Mor-057258	Magnaporthe oryzae	46.43	1.20e+00	29.30
IUUC-Mpo-057575	Magnaporthe poae	28.57	2.90e-01	31.20
IUUC-Mga-059934	Meleagris gallopavo	78.11	2.00e-121	431.00
IUUC-Mvi-060545	Microbotryum violaceum	35.85	2.40e-01	31.60
IUUC-Mmr-061356	Microcebus murinus	84.22	0.00e+00	1216.00
IUUC-Mdo-062368	Monodelphis domestica	71.49	0.00e+00	665.00
IUUC-Mmu-063573	Mus musculus	87.43	3.00e-123	436.00
IUUC-Mpu-066908	Mustela putorius furo	86.52	0.00e+00	1388.00
IUUC-Mlu-067819	Myotis lucifugus	88.05	0.00e+00	824.00
IUUC-Nle-069337	Nomascus leucogenys	96.83	0.00e+00	999.00
IUUC-Opr-070373	Ochotona princeps	79.88	3.00e-168	586.00
IUUC-Ont-072499	Oreochromis niloticus	46.71	2.00e-94	341.00
IUUC-Oan-072753	Ornithorhynchus anatinus	70.46	0.00e+00	637.00
IUUC-Ocu-074688	Oryctolagus cuniculus	85.83	0.00e+00	1336.00
IUUC-Ola-086401	Oryzias latipes	46.32	5.00e-98	353.00
IUUC-Oga-088025	Otolemur garnettii	87.40	0.00e+00	1075.00
IUUC-Oar-090208	Ovis aries	84.57	0.00e+00	1352.00
IUUC-Ptr-091655	Pan troglodytes	98.57	0.00e+00	1491.00
IUUC-Pan-092399	Papio anubis	88.13	0.00e+00	967.00
IUUC-Psi-093660	Pelodiscus sinensis	69.49	1.00e-169	591.00
IUUC-Pma-094174	Petromyzon marinus	24.10	8.10e-02	31.60
IUUC-Ppa-095430	Physcomitrella patens	36.92	4.00e-04	40.80
IUUC-Pfo-096668	Poecilia formosa	59.72	4.00e-78	286.00
IUUC-Pab-098257	Pongo abelii	97.43	0.00e+00	980.00
IUUC-Pop-099034	Populus trichocarpa	25.25	8.00e-03	36.60
IUUC-Pca-100106	Procavia capensis	78.96	0.00e+00	699.00
IUUC-Pva-102913	Pteropus vampyrus	82.14	0.00e+00	1065.00
IUUC-Rno-105371	Rattus norvegicus	79.74	0.00e+00	698.00
IUUC-Sha-107046	Sarcophilus harrisii	68.18	0.00e+00	633.00
IUUC-Sar-113170	Sorex araneus	79.41	1.00e-138	488.00
IUUC-Ssc-115247	Sus scrofa	80.75	0.00e+00	899.00
IUUC-Tgu-116891	Taeniopygia guttata	63.69	0.00e+00	701.00
IUUC-Tru-118012	Takifugu rubripes	49.46	2.00e-83	304.00
IUUC-Tsy-119649	Tarsius syrichta	86.51	2.00e-100	360.00
IUUC-Tni-120153	Tetraodon nigroviridis	65.19	7.00e-77	281.00
IUUC-Tbe-128003	Tupaia belangeri	83.45	3.00e-136	479.00
IUUC-Ttr-128220	Tursiops truncatus	84.18	0.00e+00	1300.00
IUUC-Vda-129677	Verticillium dahliae	56.00	1.40e-01	32.30
IUUC-Vpa-130679	Vicugna pacos	71.68	0.00e+00	735.00
IUUC-Xtr-132377	Xenopus tropicalis	61.72	4.00e-163	569.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence