iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Hsa-046467

UUCD1 version

UUC-HoS-00509

Ensembl Protein ID

ENSP00000350182.5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSG00000137397.18	ENST00000357569.5	ENSP00000350182.5

Annotation

Cancer Mutation
TCGA	COSMIC	CGAP	IntOGen
mRNA Expression
ArrayExpress	TCGA	ICGC	COSMIC
THPA	HPM
DNA & RNA Element
UTRdb	RepTar	miRcode	RAID2
Disease-associated Variation
GWASdb
DNA Methylation
TCGA	ICGC	COSMIC
Protein Expression/Proteomics
THPA	GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	6.30e-06	27.8	11	77
E3 activity/RING/RING	2.30e-08	36.1	16	57

Domain Profile

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwlasggk...tcPvtrqplteedlvPnltlrrliqa 67
            ee +CpI l++ + Pv++ +G+ +  ++I + + +      +cP+++++++++ +  n  lr+l+++
   Q: 11   QEEVICPICLDILQKPVTIDCGHNFCLKCITQ-IGETSCgffKCPLCKTSVRKNAIRFNSLLRNLVEK 77
           5899**************************88.433333689**********************9987 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCl+ +++ p++ +CgH f+++C+ ++      s+++f+CPlC+
   Q: 16   CPICLDILQK-PVTIDCGHNFCLKCITQI---GETSCGFFKCPLCK 57
           **********.999************888...555**********7 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

MASGQFVNKL QEEVICPICL DILQKPVTID CGHNFCLKCI TQIGETSCGF FKCPLCKTSV 60
RKNAIRFNSL LRNLVEKIQA LQASEVQSKR KEATCPRHQE MFHYFCEDDG KFLCFVCCES 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTACACATT CAAAGTATCC ATTTGTTCTC AAGAGGTAGC AAGGTAGGAC TGCCCATCTG 60
TTTTCCTCTC TTTATAATAT TTTCTAGATC CTAAATTTTA CGCTTTTCTA TCATTTCTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cho-024490	Choloepus hoffmanni	49.73	2.00e-91	329.00
IUUC-Itr-049020	Ictidomys tridecemlineatus	63.91	4.00e-116	411.00
IUUC-Ocu-074338	Oryctolagus cuniculus	61.70	2.00e-119	421.00
IUUC-Oar-089628	Ovis aries	60.82	2.00e-119	422.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence