iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062339

UUCD1 version

UUC-MoD-01121

Ensembl Protein ID

ENSMODP00000013790.3

UniProt Accession

F6ZBV9; F6ZBV9_MONDO

Protein Name

Uncharacterized protein

Gene Name

USP3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000011011.3	ENSMODT00000014042.3	ENSMODP00000013790.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	9.70e-101	337.5	74	425

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle...........kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalk 78
           tGl+NlgNtC+mN++LQ+Lsni+++ ++++e             +++ + +++ +++ +l+++++k + +lw+++++a+sp++l+ +++
   Q: 74   TGLRNLGNTCFMNAILQSLSNIQQFCCYFKElpavelrngktAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVW 162
           7******************************888888777765555555555688889******************************* PP
   S: 79   keaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssree 167
           k+ ++f+gy+qqDa+Ef+++lld+l+ el+   n    +   +++s+l + +++   +  +++++ +F+g l++++ cl c+++s +++
   Q: 163  KIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSVILQENSSL-SASNKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFD 250
           *****************************7644444444444443344.445688899999**************************** PP
   S: 168  pfldlslpvpgkeetkke.........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksre 247
           pfldlsl++p++  +k +         sl+dcL+sft  eel++ + y c kckkkq+++kk++++klP+vL+lhLkRf+++   + r+
   Q: 251  PFLDLSLDIPSQFRNKRSknqengplcSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTA--YLRN 337
           **********66655444667899999****************************************************7755..799* PP
   S: 248  kinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlf 334
           k++++vefpl+ Ld++ ++ +pe++  e++ Y+L avvvH+G +++sGHY+ay+ + +g+W++f+Ds+Vt ++ee+v++   ++aY+lf
   Q: 338  KVDTYVEFPLRgLDMKCYLLEPENSGPESCLYDLAAVVVHHGsGVGSGHYTAYATH-EGRWFHFNDSTVTLTDEETVVK---AKAYILF 422
           ********************************************************.9*********************...******* PP
   S: 335  Ykr 337
           Y +
   Q: 423  YVE 425
           *76 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MDCSSYSTYC YRCDDFVVND TKLGLVQKVR EHLQNLENSA FTADRHRKRK LLENSSLNSK 60
LLKVNGSTTA LCATGLRNLG NTCFMNAILQ SLSNIQQFCC YFKELPAVEL RNGKTAGRRT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAATATTTC AGCTTGTATA TTTGTATGTT TTTCTTTTTT TTTTAATAGT GTGCCGGTCC 60
AACAAAAGCC CCTGGGTCTG TTTGACTTGT TCAAGTGTCC ATTGTGGAAG GTAGGTACTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0070938--C:contractile ring
GO:0000790--C:nuclear chromatin
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0006281--P:DNA repair
GO:0016578--P:histone deubiquitination
GO:0000278--P:mitotic cell cycle
GO:0031647--P:regulation of protein stability
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001537	Ailuropoda melanoleuca	97.24	0.00e+00	775.00
IUUC-Apl-003358	Anas platyrhynchos	97.70	0.00e+00	797.00
IUUC-Aca-004454	Anolis carolinensis	94.85	0.00e+00	709.00
IUUC-Ame-011544	Astyanax mexicanus	77.55	7.00e-173	600.00
IUUC-Bta-012738	Bos taurus	97.01	0.00e+00	757.00
IUUC-Cel-018186	Caenorhabditis elegans	37.08	2.00e-55	210.00
IUUC-Cja-018893	Callithrix jacchus	96.78	0.00e+00	765.00
IUUC-Cfa-020607	Canis familiaris	97.47	0.00e+00	758.00
IUUC-Cpo-021828	Cavia porcellus	95.40	0.00e+00	742.00
IUUC-Csa-023884	Chlorocebus sabaeus	97.65	0.00e+00	775.00
IUUC-Cho-024863	Choloepus hoffmanni	90.11	0.00e+00	690.00
IUUC-Dre-028452	Danio rerio	76.09	0.00e+00	627.00
IUUC-Dno-029531	Dasypus novemcinctus	97.01	0.00e+00	758.00
IUUC-Dor-030913	Dipodomys ordii	86.79	2.00e-142	499.00
IUUC-Ete-032611	Echinops telfairi	90.34	0.00e+00	701.00
IUUC-Eca-033622	Equus caballus	97.47	0.00e+00	760.00
IUUC-Eeu-035268	Erinaceus europaeus	91.95	0.00e+00	690.00
IUUC-Fca-035801	Felis catus	97.24	0.00e+00	792.00
IUUC-Fal-036749	Ficedula albicollis	96.55	0.00e+00	751.00
IUUC-Gmo-039598	Gadus morhua	78.87	0.00e+00	640.00
IUUC-Gga-040883	Gallus gallus	97.93	0.00e+00	763.00
IUUC-Gac-042235	Gasterosteus aculeatus	79.77	0.00e+00	640.00
IUUC-Ggo-044767	Gorilla gorilla	91.06	0.00e+00	722.00
IUUC-Hsa-046581	Homo sapiens	97.24	0.00e+00	792.00
IUUC-Itr-047898	Ictidomys tridecemlineatus	97.24	0.00e+00	757.00
IUUC-Lch-049732	Latimeria chalumnae	93.30	0.00e+00	768.00
IUUC-Loc-052371	Lepisosteus oculatus	91.22	0.00e+00	754.00
IUUC-Laf-054565	Loxodonta africana	97.01	0.00e+00	757.00
IUUC-Mcc-055522	Macaca mulatta	97.70	0.00e+00	795.00
IUUC-Meu-056754	Macropus eugenii	87.10	2.00e-130	459.00
IUUC-Mga-060095	Meleagris gallopavo	97.16	2.00e-153	534.00
IUUC-Mmr-060839	Microcebus murinus	97.24	0.00e+00	756.00
IUUC-Mmu-063638	Mus musculus	96.55	0.00e+00	732.00
IUUC-Mpu-066647	Mustela putorius furo	97.47	0.00e+00	760.00
IUUC-Mlu-067921	Myotis lucifugus	96.09	0.00e+00	774.00
IUUC-Nle-069752	Nomascus leucogenys	97.70	0.00e+00	796.00
IUUC-Opr-070636	Ochotona princeps	83.68	4.00e-175	607.00
IUUC-Ont-071638	Oreochromis niloticus	78.80	0.00e+00	664.00
IUUC-Oan-073417	Ornithorhynchus anatinus	91.26	0.00e+00	728.00
IUUC-Ocu-074620	Oryctolagus cuniculus	95.63	0.00e+00	745.00
IUUC-Ola-087281	Oryzias latipes	79.03	0.00e+00	630.00
IUUC-Olu-087697	Ostreococcus lucimarinus	40.33	5.00e-49	187.00
IUUC-Oga-088448	Otolemur garnettii	96.09	0.00e+00	782.00
IUUC-Oar-090132	Ovis aries	97.24	0.00e+00	756.00
IUUC-Ptr-090696	Pan troglodytes	97.47	0.00e+00	794.00
IUUC-Pan-092124	Papio anubis	97.24	0.00e+00	791.00
IUUC-Psi-093801	Pelodiscus sinensis	97.70	0.00e+00	761.00
IUUC-Pma-094300	Petromyzon marinus	70.79	8.00e-99	352.00
IUUC-Pfo-096330	Poecilia formosa	81.50	0.00e+00	653.00
IUUC-Pab-098191	Pongo abelii	97.70	0.00e+00	796.00
IUUC-Pca-100341	Procavia capensis	95.94	2.00e-157	548.00
IUUC-Pva-103177	Pteropus vampyrus	96.78	0.00e+00	745.00
IUUC-Rno-105048	Rattus norvegicus	95.63	0.00e+00	725.00
IUUC-Sha-107429	Sarcophilus harrisii	100.00	0.00e+00	773.00
IUUC-Sar-113024	Sorex araneus	95.63	0.00e+00	748.00
IUUC-Ssc-115749	Sus scrofa	95.73	8.00e-151	526.00
IUUC-Tgu-117277	Taeniopygia guttata	96.55	0.00e+00	786.00
IUUC-Tru-117844	Takifugu rubripes	80.18	0.00e+00	650.00
IUUC-Tsy-119456	Tarsius syrichta	93.79	0.00e+00	748.00
IUUC-Tni-120251	Tetraodon nigroviridis	76.55	0.00e+00	671.00
IUUC-Tbe-127423	Tupaia belangeri	89.89	0.00e+00	672.00
IUUC-Ttr-128401	Tursiops truncatus	89.66	0.00e+00	676.00
IUUC-Vpa-130549	Vicugna pacos	87.86	4.00e-136	477.00
IUUC-Xtr-131892	Xenopus tropicalis	84.62	0.00e+00	660.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence