iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-060095

UUCD1 version

UUC-MeG-00871

Ensembl Protein ID

ENSMGAP00000003931.2

UniProt Accession

G1MYB9; G1MYB9_MELGA

Protein Name

Ubiquitinyl hydrolase 1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000004108.2	ENSMGAT00000004641.2	ENSMGAP00000003931.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.00e-42	145.3	129	320
UBD/ZnF/ZnF_UBP	2.20e-25	88.4	1	74

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle...........kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalk 78
           tGl+NlgNtC+mN++LQ+Lsni+++ ++++e             +++ + +++ +++ +l+++++k + +lw+++++a+sp++l+ +++
   Q: 129  TGLRNLGNTCFMNAILQSLSNIQQFCCYFKElpavelrngktAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVW 217
           7******************************888888777765555555555688889******************************* PP
   S: 79   keaeefs..gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssr 165
           k+ ++fs  gy+qqDa+Ef+++lld+l+ el+   n    +   ++ +++   +++   +  +++++ +F+g l++++ cl c+++s +
   Q: 218  KIMPNFSsrGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSVILQE-NSSLTASSKCCINGASTVVTAIFGGILQNEVNCLICGTESRK 305
           ******999**********************663333333333333.3334445788999999************************** PP
   S: 166  eepfldlslpvpgke 180
           ++pfldlsl++p++ 
   Q: 306  FDPFLDLSLDIPSQF 320
           ************764 PP

UBD/ZnF/ZnF_UBP

   S: 5    vcdktenlWlcLtcgsvgCGRyvegHalkHyeetqhpl................vlslstlsvycYacddyvhr 62
           vc++++++W+cLtc+sv+CGRyv+gHa+kHye++q p+                ++++s++s+ycY+cdd+v++
   Q: 1    VCRSNKSPWVCLTCSSVHCGRYVNGHAKKHYEDAQIPMtnhkktekqekvqhtvCMDCSSYSTYCYRCDDFVVN 74
           6***********************************************************************85 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

VCRSNKSPWV CLTCSSVHCG RYVNGHAKKH YEDAQIPMTN HKKTEKQEKV QHTVCMDCSS 60
YSTYCYRCDD FVVNDTKLGL VQKVREHLQN LENSAFTSDR HRKRKLLENS SLNSKLLKVN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGTGCCGGT CAAATAAAAG CCCGTGGGTC TGTCTGACGT GCTCCAGTGT CCATTGTGGA 60
AGGTGGGTAT CAAGTGTTGG TGTGAAACAT GTTCAGTCAG GCTTCTTGCT TGCTTGGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001537	Ailuropoda melanoleuca	94.66	0.00e+00	639.00
IUUC-Apl-003358	Anas platyrhynchos	99.11	0.00e+00	696.00
IUUC-Aca-004454	Anolis carolinensis	92.04	2.00e-176	611.00
IUUC-Ame-011544	Astyanax mexicanus	72.92	7.00e-148	516.00
IUUC-Bta-012738	Bos taurus	94.96	0.00e+00	640.00
IUUC-Cja-018893	Callithrix jacchus	94.07	0.00e+00	669.00
IUUC-Cfa-020607	Canis familiaris	94.66	0.00e+00	639.00
IUUC-Cpo-021828	Cavia porcellus	92.58	5.00e-180	623.00
IUUC-Csa-023884	Chlorocebus sabaeus	94.85	7.00e-155	539.00
IUUC-Cho-024863	Choloepus hoffmanni	80.12	1.00e-147	515.00
IUUC-Dre-028452	Danio rerio	70.00	4.00e-144	504.00
IUUC-Dno-029531	Dasypus novemcinctus	93.47	0.00e+00	635.00
IUUC-Dor-030913	Dipodomys ordii	86.01	1.00e-173	602.00
IUUC-Ete-032611	Echinops telfairi	93.18	0.00e+00	633.00
IUUC-Eca-033622	Equus caballus	94.66	0.00e+00	639.00
IUUC-Eeu-035268	Erinaceus europaeus	88.39	2.00e-164	572.00
IUUC-Fca-035801	Felis catus	93.77	0.00e+00	669.00
IUUC-Fal-036749	Ficedula albicollis	97.63	0.00e+00	652.00
IUUC-Gmo-039598	Gadus morhua	74.78	3.00e-147	514.00
IUUC-Gga-040883	Gallus gallus	99.41	0.00e+00	661.00
IUUC-Gac-042235	Gasterosteus aculeatus	73.45	2.00e-142	498.00
IUUC-Ggo-044767	Gorilla gorilla	86.09	9.00e-174	602.00
IUUC-Hsa-046581	Homo sapiens	94.36	0.00e+00	673.00
IUUC-Itr-047898	Ictidomys tridecemlineatus	94.66	0.00e+00	638.00
IUUC-Lch-049732	Latimeria chalumnae	88.79	0.00e+00	626.00
IUUC-Loc-052371	Lepisosteus oculatus	86.43	1.00e-175	608.00
IUUC-Laf-054565	Loxodonta africana	94.36	0.00e+00	638.00
IUUC-Mcc-055522	Macaca mulatta	94.36	0.00e+00	673.00
IUUC-Meu-056754	Macropus eugenii	86.65	3.00e-161	561.00
IUUC-Mmr-060839	Microcebus murinus	94.66	0.00e+00	637.00
IUUC-Mdo-062339	Monodelphis domestica	97.16	2.00e-153	535.00
IUUC-Mmu-063638	Mus musculus	94.36	0.00e+00	636.00
IUUC-Mpu-066647	Mustela putorius furo	95.39	2.00e-151	528.00
IUUC-Mlu-067921	Myotis lucifugus	94.66	0.00e+00	637.00
IUUC-Nle-069752	Nomascus leucogenys	94.66	0.00e+00	674.00
IUUC-Opr-070636	Ochotona princeps	79.46	1.00e-143	503.00
IUUC-Ont-071638	Oreochromis niloticus	72.53	7.00e-136	477.00
IUUC-Oan-073417	Ornithorhynchus anatinus	87.24	8.00e-176	609.00
IUUC-Ocu-074620	Oryctolagus cuniculus	93.47	0.00e+00	637.00
IUUC-Ola-087281	Oryzias latipes	76.16	2.00e-123	435.00
IUUC-Oga-088448	Otolemur garnettii	93.18	0.00e+00	663.00
IUUC-Oar-090132	Ovis aries	94.66	0.00e+00	638.00
IUUC-Ptr-090696	Pan troglodytes	94.36	0.00e+00	674.00
IUUC-Pan-092124	Papio anubis	94.07	0.00e+00	670.00
IUUC-Psi-093801	Pelodiscus sinensis	97.52	2.00e-153	535.00
IUUC-Pma-094472	Petromyzon marinus	73.89	1.00e-95	341.00
IUUC-Pfo-096330	Poecilia formosa	76.18	6.00e-153	533.00
IUUC-Pab-098191	Pongo abelii	94.36	0.00e+00	672.00
IUUC-Pca-100341	Procavia capensis	92.88	0.00e+00	630.00
IUUC-Pva-103177	Pteropus vampyrus	93.77	1.00e-180	625.00
IUUC-Rno-105048	Rattus norvegicus	92.04	1.00e-178	619.00
IUUC-Sha-107429	Sarcophilus harrisii	97.33	0.00e+00	651.00
IUUC-Sar-113024	Sorex araneus	91.14	3.00e-166	577.00
IUUC-Ssc-115749	Sus scrofa	94.89	2.00e-145	507.00
IUUC-Tgu-117277	Taeniopygia guttata	97.33	0.00e+00	685.00
IUUC-Tru-117844	Takifugu rubripes	75.52	2.00e-151	528.00
IUUC-Tsy-119456	Tarsius syrichta	94.05	0.00e+00	636.00
IUUC-Tni-120251	Tetraodon nigroviridis	73.75	2.00e-147	515.00
IUUC-Tbe-127423	Tupaia belangeri	84.87	4.00e-160	557.00
IUUC-Ttr-128401	Tursiops truncatus	85.12	4.00e-160	557.00
IUUC-Vpa-130549	Vicugna pacos	84.52	1.00e-159	555.00
IUUC-Xtr-131892	Xenopus tropicalis	80.06	2.00e-158	551.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence