iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093801

Ensembl Protein ID

ENSPSIP00000006686.1

UniProt Accession

K7FF76; K7FF76_PELSI

Genbank Protein ID

ENSPSIP00000006686

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01110667

Gene Name

USP3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000006188.1	ENSPSIT00000006723.1	ENSPSIP00000006686.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.40e-101	337.7	74	424

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle...........kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalk 78
           tGl+NlgNtC+mN++LQ+Lsni+++ ++++e             +++ + +++ +++ +l+++++k + +lw+++++a+sp++l+ +++
   Q: 74   TGLRNLGNTCFMNAILQSLSNIQQFCCYFKElpavelrngktAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVW 162
           7******************************888888777765555555555688889******************************* PP
   S: 79   keaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssree 167
           k+ ++f+gy+qqDa+Ef+++lld+l+ el+   n    +   +++s ls + ++   +  +++++ +F+g l++++ cl c+++s +++
   Q: 163  KIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSVILQENSGLSAS-NKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFD 250
           *****************************7755555555555555555554.688899999**************************** PP
   S: 168  pfldlslpvpgkeetkke.........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksre 247
           pfldlsl++p++  +k +         +l+dcL+sft  eel++ + y c kckkkq+++kk++++klP+vL+lhLkRf+++e  + r+
   Q: 251  PFLDLSLDIPSQFRNKRTknqengpicTLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTE--YLRN 337
           **********66655444667899999****************************************************8866..799* PP
   S: 248  kinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlf 334
           k++++vefpl+ Ld++ f+ +pe++  e++ Y+L avvvH+G +++sGHY+ay+ + +g+W++f+Ds+Vt ++ee+v++   ++aY+lf
   Q: 338  KVDTYVEFPLRgLDMKCFLLEPENSGPESCLYDLAAVVVHHGsGVGSGHYTAYATH-EGRWFHFNDSTVTLTDEETVVK---AKAYILF 422
           ********************************************************.9*********************...******* PP
   S: 335  Yk 336
           Y 
   Q: 423  YV 424
           *6 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MDCSSYSTYC YRCDDFVVND TKLGLVQKVR EHLQNLENSA FTTDRHRKRK LLENSSLNSK 60
LLKVNGSTTA LCATGLRNLG NTCFMNAILQ SLSNIQQFCC YFKELPAVEL RNGKTAGRRT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTGCCGATC CAATAAAAGT CCCTGGGTCT GTCTGACTTG TTCAAGTGTC CATTGTGGAA 60
GGTAGGTACA GGACATAATA ATTTGGAAAT TACTTTACCT CCTCTTTTTA TAATCTTTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0070938--C:contractile ring
GO:0000790--C:nuclear chromatin
GO:0005654--C:nucleoplasm
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0006281--P:DNA repair
GO:0016578--P:histone deubiquitination
GO:0000278--P:mitotic cell cycle
GO:0031647--P:regulation of protein stability
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001537	Ailuropoda melanoleuca	95.86	0.00e+00	766.00
IUUC-Apl-003358	Anas platyrhynchos	97.70	0.00e+00	795.00
IUUC-Aca-004454	Anolis carolinensis	94.61	0.00e+00	707.00
IUUC-Ame-011544	Astyanax mexicanus	77.55	3.00e-172	598.00
IUUC-Bta-012738	Bos taurus	96.09	0.00e+00	750.00
IUUC-Cel-018186	Caenorhabditis elegans	37.68	8.00e-56	211.00
IUUC-Cja-018893	Callithrix jacchus	95.86	0.00e+00	759.00
IUUC-Cfa-020607	Canis familiaris	96.55	0.00e+00	752.00
IUUC-Cpo-021828	Cavia porcellus	94.02	0.00e+00	733.00
IUUC-Csa-023884	Chlorocebus sabaeus	96.71	0.00e+00	769.00
IUUC-Cho-024863	Choloepus hoffmanni	89.20	0.00e+00	683.00
IUUC-Dre-028452	Danio rerio	75.86	2.00e-180	625.00
IUUC-Dno-029531	Dasypus novemcinctus	96.09	0.00e+00	753.00
IUUC-Dor-030913	Dipodomys ordii	86.07	7.00e-142	496.00
IUUC-Ete-032611	Echinops telfairi	89.20	0.00e+00	694.00
IUUC-Eca-033622	Equus caballus	96.55	0.00e+00	753.00
IUUC-Eeu-035268	Erinaceus europaeus	90.11	0.00e+00	678.00
IUUC-Fca-035801	Felis catus	96.32	0.00e+00	786.00
IUUC-Fal-036749	Ficedula albicollis	96.32	0.00e+00	748.00
IUUC-Gmo-039598	Gadus morhua	78.64	0.00e+00	637.00
IUUC-Gga-040883	Gallus gallus	97.93	0.00e+00	761.00
IUUC-Gac-042235	Gasterosteus aculeatus	79.31	0.00e+00	635.00
IUUC-Ggo-044767	Gorilla gorilla	90.14	0.00e+00	716.00
IUUC-Hsa-046581	Homo sapiens	96.32	0.00e+00	786.00
IUUC-Itr-047898	Ictidomys tridecemlineatus	96.32	0.00e+00	751.00
IUUC-Lch-049732	Latimeria chalumnae	93.07	0.00e+00	767.00
IUUC-Loc-052371	Lepisosteus oculatus	91.22	0.00e+00	752.00
IUUC-Laf-054565	Loxodonta africana	96.09	0.00e+00	750.00
IUUC-Mcc-055522	Macaca mulatta	96.78	0.00e+00	790.00
IUUC-Meu-056754	Macropus eugenii	86.02	2.00e-129	455.00
IUUC-Mga-060095	Meleagris gallopavo	97.52	1.00e-153	535.00
IUUC-Mmr-060839	Microcebus murinus	96.32	0.00e+00	749.00
IUUC-Mdo-062339	Monodelphis domestica	97.70	0.00e+00	761.00
IUUC-Mmu-063638	Mus musculus	94.71	0.00e+00	721.00
IUUC-Mpu-066647	Mustela putorius furo	96.55	0.00e+00	754.00
IUUC-Mlu-067921	Myotis lucifugus	94.71	0.00e+00	766.00
IUUC-Nle-069752	Nomascus leucogenys	96.78	0.00e+00	790.00
IUUC-Opr-070636	Ochotona princeps	82.99	8.00e-174	602.00
IUUC-Ont-071638	Oreochromis niloticus	78.57	0.00e+00	661.00
IUUC-Oan-073417	Ornithorhynchus anatinus	90.80	0.00e+00	726.00
IUUC-Ocu-074620	Oryctolagus cuniculus	93.79	0.00e+00	734.00
IUUC-Ola-087281	Oryzias latipes	78.57	0.00e+00	626.00
IUUC-Olu-087697	Ostreococcus lucimarinus	40.39	5.00e-48	184.00
IUUC-Oga-088448	Otolemur garnettii	95.17	0.00e+00	776.00
IUUC-Oar-090132	Ovis aries	96.32	0.00e+00	751.00
IUUC-Ptr-090696	Pan troglodytes	96.55	0.00e+00	788.00
IUUC-Pan-092124	Papio anubis	96.55	0.00e+00	786.00
IUUC-Pma-094300	Petromyzon marinus	71.16	6.00e-99	353.00
IUUC-Pfo-096330	Poecilia formosa	80.41	0.00e+00	652.00
IUUC-Pab-098191	Pongo abelii	96.78	0.00e+00	790.00
IUUC-Pca-100341	Procavia capensis	95.00	4.00e-156	544.00
IUUC-Pva-103177	Pteropus vampyrus	95.86	0.00e+00	738.00
IUUC-Rno-105048	Rattus norvegicus	94.25	0.00e+00	716.00
IUUC-Sha-107429	Sarcophilus harrisii	97.70	0.00e+00	759.00
IUUC-Sar-113024	Sorex araneus	94.71	0.00e+00	741.00
IUUC-Ssc-115749	Sus scrofa	94.66	9.00e-150	522.00
IUUC-Tgu-117277	Taeniopygia guttata	96.09	0.00e+00	781.00
IUUC-Tru-117844	Takifugu rubripes	79.72	0.00e+00	646.00
IUUC-Tsy-119456	Tarsius syrichta	93.33	0.00e+00	744.00
IUUC-Tni-120251	Tetraodon nigroviridis	75.63	0.00e+00	664.00
IUUC-Tbe-127423	Tupaia belangeri	88.28	0.00e+00	667.00
IUUC-Ttr-128401	Tursiops truncatus	88.74	0.00e+00	670.00
IUUC-Vpa-130549	Vicugna pacos	86.79	3.00e-135	474.00
IUUC-Xtr-131892	Xenopus tropicalis	83.94	0.00e+00	655.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence