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Tag Content
UUCD2 ID IUUC-Bta-012427
UUCD1 version UUC-BoT-00718
Ensembl Protein ID ENSBTAP00000020952.5
UniProt Accession F6R1H3; F6R1H3_BOVIN
Genbank Protein ID ENSBTAP00000020952
Protein Name Uncharacterized protein
Genbank Nucleotide ID DAAA02052519
Gene Name PML
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSBTAG00000015779.5 ENSBTAT00000020952.5 ENSBTAP00000020952.5
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 75.37 0.00e+00 1239.00 IUUC-Hsa-045861
E3 activity/RING/RING 63.70 0.00e+00 1009.00 IUUC-Mmu-063118
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Bos taurus
Protein Sequence
(Fasta)
MQQDPEPAGS PGPQQDPALP HSPSMPPPES LSEGHQSSHS DSPTEQATEE EFQFLRCQGC 60
RAEAKCPKLL PCLHTLCSGC LEESSMQCPV CRAPWPSGAG TQALDNVFFE SLQRRLSVYQ 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Bta-012427|E3,RING|Bos taurus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GTTTCTCCGC TCTCGAAGAG CGAAACAGAA TCGAAACTGC GCTGGATTCC ATGCAGCAGG 60
ATCCGGAACC TGCTGGATCT CCGGGGCCCC AGCAGGACCC CGCACTGCCC CATTCCCCCA 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Bta-012427|E3,RING|Bos taurus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR021978--DUF3583
IPR012337--RNaseH-like_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF12126--DUF3583
PF00643--zf-B_box

SMART

SM00336--BBOX
SM00184--RING

Gene Ontology

GO:0005829--C:cytosol
GO:0042406--C:extrinsic component of endoplasmic reticulum membrane
GO:0000784--C:nuclear chromosome, telomeric region
GO:0016363--C:nuclear matrix
GO:0031965--C:nuclear membrane
GO:0005730--C:nucleolus
GO:0016605--C:PML body
GO:0008270--F:zinc ion binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0060444--P:branching involved in mammary gland duct morphogenesis
GO:0007050--P:cell cycle arrest
GO:0045165--P:cell fate commitment
GO:0071353--P:cellular response to interleukin-4
GO:0090398--P:cellular senescence
GO:0032922--P:circadian regulation of gene expression
GO:0007182--P:common-partner SMAD protein phosphorylation
GO:0006977--P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0032469--P:endoplasmic reticulum calcium ion homeostasis
GO:0043153--P:entrainment of circadian clock by photoperiod
GO:0097191--P:extrinsic apoptotic signaling pathway
GO:0010761--P:fibroblast migration
GO:0045087--P:innate immune response
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0070059--P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0008631--P:intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0051457--P:maintenance of protein location in nucleus
GO:0030099--P:myeloid cell differentiation
GO:0016525--P:negative regulation of angiogenesis
GO:0030308--P:negative regulation of cell growth
GO:0008285--P:negative regulation of cell proliferation
GO:0050713--P:negative regulation of interleukin-1 beta secretion
GO:2000059--P:negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:1902187--P:negative regulation of viral release from host cell
GO:0030578--P:PML body organization
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:0048146--P:positive regulation of fibroblast proliferation
GO:0045345--P:positive regulation of MHC class I biosynthetic process
GO:0032206--P:positive regulation of telomere maintenance
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0006461--P:protein complex assembly
GO:0010522--P:regulation of calcium ion transport into cytosol
GO:0030155--P:regulation of cell adhesion
GO:2000779--P:regulation of double-strand break repair
GO:0001932--P:regulation of protein phosphorylation
GO:0010332--P:response to gamma radiation
GO:0001666--P:response to hypoxia
GO:0009411--P:response to UV
GO:0048384--P:retinoic acid receptor signaling pathway
GO:0007184--P:SMAD protein import into nucleus
GO:0007179--P:transforming growth factor beta receptor signaling pathway

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001901 Ailuropoda melanoleuca 74.80 0.00e+00 1134.00
IUUC-Cja-019029 Callithrix jacchus 74.52 0.00e+00 1169.00
IUUC-Cfa-021127 Canis familiaris 70.95 0.00e+00 1099.00
IUUC-Cpo-022553 Cavia porcellus 64.36 0.00e+00 934.00
IUUC-Csa-023187 Chlorocebus sabaeus 74.30 0.00e+00 821.00
IUUC-Cho-024937 Choloepus hoffmanni 67.11 4.00e-97 349.00
IUUC-Dno-029326 Dasypus novemcinctus 72.05 0.00e+00 1076.00
IUUC-Dor-030808 Dipodomys ordii 59.42 0.00e+00 691.00
IUUC-Ete-032746 Echinops telfairi 54.50 2.00e-100 360.00
IUUC-Eca-033234 Equus caballus 75.45 0.00e+00 1131.00
IUUC-Fca-035648 Felis catus 74.69 0.00e+00 1182.00
IUUC-Ggo-044927 Gorilla gorilla 75.37 0.00e+00 1202.00
IUUC-Hsa-045861 Homo sapiens 75.37 0.00e+00 1201.00
IUUC-Itr-047861 Ictidomys tridecemlineatus 73.23 0.00e+00 1186.00
IUUC-Loc-052276 Lepisosteus oculatus 33.01 1.00e-52 201.00
IUUC-Laf-054059 Loxodonta africana 69.78 0.00e+00 1091.00
IUUC-Meu-056495 Macropus eugenii 53.82 5.00e-102 365.00
IUUC-Mga-059224 Meleagris gallopavo 31.60 2.00e-76 280.00
IUUC-Mmr-061507 Microcebus murinus 70.13 0.00e+00 1080.00
IUUC-Mdo-062196 Monodelphis domestica 44.91 0.00e+00 629.00
IUUC-Mmu-063118 Mus musculus 63.70 0.00e+00 1018.00
IUUC-Mpu-066024 Mustela putorius furo 69.17 0.00e+00 1071.00
IUUC-Mlu-066980 Myotis lucifugus 71.30 0.00e+00 1090.00
IUUC-Nle-069779 Nomascus leucogenys 74.69 0.00e+00 1148.00
IUUC-Ocu-074016 Oryctolagus cuniculus 66.99 0.00e+00 992.00
IUUC-Oga-089085 Otolemur garnettii 66.04 0.00e+00 1031.00
IUUC-Oar-089980 Ovis aries 91.96 0.00e+00 1513.00
IUUC-Ptr-091681 Pan troglodytes 75.31 0.00e+00 1198.00
IUUC-Pan-091965 Papio anubis 73.67 0.00e+00 1145.00
IUUC-Psi-093577 Pelodiscus sinensis 37.83 7.00e-120 424.00
IUUC-Pab-098215 Pongo abelii 72.86 0.00e+00 629.00
IUUC-Pca-100883 Procavia capensis 68.14 0.00e+00 794.00
IUUC-Pva-102465 Pteropus vampyrus 71.20 0.00e+00 811.00
IUUC-Rno-105120 Rattus norvegicus 63.70 0.00e+00 1036.00
IUUC-Sar-113320 Sorex araneus 62.32 3.00e-82 300.00
IUUC-Ssc-116042 Sus scrofa 77.17 0.00e+00 1272.00
IUUC-Tbe-127880 Tupaia belangeri 68.85 1.00e-138 487.00
Created Date 25-Jun-2017

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