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Tag Content
iUUCD ID IUUC-Oga-089085
Ensembl Protein ID ENSOGAP00000006327.2
UniProt Accession H0WVI6; H0WVI6_OTOGA
Genbank Protein ID ENSOGAP00000006327
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAQR03026381
Gene Name PML
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSOGAG00000007066.2 ENSOGAT00000007070.2 ENSOGAP00000006327.2
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 71.44 0.00e+00 1125.00 IUUC-Hsa-045861
E3 activity/RING/RING 58.41 0.00e+00 876.00 IUUC-Mmu-063118
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Otolemur garnettii
Protein Sequence
(Fasta)
EEPAPSGSSR PQRKLAFQRT PTMPPPDNPS EDQLPNPSHT EEATKDDEFQ FLHCQHCRME 60
AKCPKLLPCL HTLCSGCLEP PVTQCPICQE PWPPGTDTPV LDNVFFESLQ RRLSVYRQIV 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Oga-089085|E3,RING|Otolemur garnettii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GAGGAGCCTG CACCATCCGG ATCTTCGCGG CCGCAGCGGA AACTTGCCTT TCAGCGCACA 60
CCCACCATGC CTCCCCCGGA TAACCCCTCC GAAGACCAGC TGCCCAACCC GAGCCACACA 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Oga-089085|E3,RING|Otolemur garnettii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR021978--DUF3583
IPR012337--RNaseH-like_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF12126--DUF3583
PF00643--zf-B_box

SMART

SM00336--BBOX

Gene Ontology

GO:0005829--C:cytosol
GO:0042406--C:extrinsic component of endoplasmic reticulum membrane
GO:0000784--C:nuclear chromosome, telomeric region
GO:0016363--C:nuclear matrix
GO:0031965--C:nuclear membrane
GO:0005730--C:nucleolus
GO:0016605--C:PML body
GO:0008270--F:zinc ion binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0060444--P:branching involved in mammary gland duct morphogenesis
GO:0007050--P:cell cycle arrest
GO:0045165--P:cell fate commitment
GO:0071353--P:cellular response to interleukin-4
GO:0090398--P:cellular senescence
GO:0032922--P:circadian regulation of gene expression
GO:0007182--P:common-partner SMAD protein phosphorylation
GO:0006977--P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0032469--P:endoplasmic reticulum calcium ion homeostasis
GO:0043153--P:entrainment of circadian clock by photoperiod
GO:0097191--P:extrinsic apoptotic signaling pathway
GO:0010761--P:fibroblast migration
GO:0045087--P:innate immune response
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0070059--P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0008631--P:intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0051457--P:maintenance of protein location in nucleus
GO:0030099--P:myeloid cell differentiation
GO:0016525--P:negative regulation of angiogenesis
GO:0030308--P:negative regulation of cell growth
GO:0008285--P:negative regulation of cell proliferation
GO:0050713--P:negative regulation of interleukin-1 beta secretion
GO:2000059--P:negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:1902187--P:negative regulation of viral release from host cell
GO:0030578--P:PML body organization
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:0048146--P:positive regulation of fibroblast proliferation
GO:0045345--P:positive regulation of MHC class I biosynthetic process
GO:0032206--P:positive regulation of telomere maintenance
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0006461--P:protein complex assembly
GO:0010522--P:regulation of calcium ion transport into cytosol
GO:0030155--P:regulation of cell adhesion
GO:2000779--P:regulation of double-strand break repair
GO:0001932--P:regulation of protein phosphorylation
GO:0010332--P:response to gamma radiation
GO:0001666--P:response to hypoxia
GO:0009411--P:response to UV
GO:0048384--P:retinoic acid receptor signaling pathway
GO:0007184--P:SMAD protein import into nucleus
GO:0007179--P:transforming growth factor beta receptor signaling pathway

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001901 Ailuropoda melanoleuca 66.94 0.00e+00 1005.00
IUUC-Bta-012427 Bos taurus 67.48 0.00e+00 1054.00
IUUC-Cja-019029 Callithrix jacchus 70.09 0.00e+00 1089.00
IUUC-Cfa-021127 Canis familiaris 63.84 0.00e+00 980.00
IUUC-Cpo-022553 Cavia porcellus 63.76 0.00e+00 929.00
IUUC-Csa-023187 Chlorocebus sabaeus 67.77 0.00e+00 742.00
IUUC-Cho-024937 Choloepus hoffmanni 57.28 1.00e-78 287.00
IUUC-Dno-029326 Dasypus novemcinctus 65.96 0.00e+00 976.00
IUUC-Dor-030808 Dipodomys ordii 53.29 8.00e-172 597.00
IUUC-Ete-032746 Echinops telfairi 47.79 2.00e-148 520.00
IUUC-Eca-033234 Equus caballus 68.59 0.00e+00 1029.00
IUUC-Fca-035648 Felis catus 69.65 0.00e+00 1082.00
IUUC-Ggo-044927 Gorilla gorilla 72.01 0.00e+00 1143.00
IUUC-Hsa-045861 Homo sapiens 71.78 0.00e+00 1138.00
IUUC-Itr-047861 Ictidomys tridecemlineatus 68.58 0.00e+00 1080.00
IUUC-Loc-052276 Lepisosteus oculatus 34.39 3.00e-48 187.00
IUUC-Laf-054059 Loxodonta africana 66.17 0.00e+00 974.00
IUUC-Meu-056495 Macropus eugenii 53.02 5.00e-100 358.00
IUUC-Mga-059224 Meleagris gallopavo 41.98 2.00e-41 164.00
IUUC-Mmr-061507 Microcebus murinus 76.00 0.00e+00 1175.00
IUUC-Mdo-062196 Monodelphis domestica 44.87 2.00e-174 607.00
IUUC-Mmu-063118 Mus musculus 58.41 0.00e+00 931.00
IUUC-Mpu-066024 Mustela putorius furo 63.91 0.00e+00 983.00
IUUC-Mlu-066980 Myotis lucifugus 68.94 0.00e+00 1009.00
IUUC-Nle-069779 Nomascus leucogenys 71.11 0.00e+00 1085.00
IUUC-Ocu-074016 Oryctolagus cuniculus 59.34 0.00e+00 895.00
IUUC-Oar-089980 Ovis aries 63.83 0.00e+00 994.00
IUUC-Ptr-091681 Pan troglodytes 71.73 0.00e+00 1136.00
IUUC-Pan-091965 Papio anubis 70.09 0.00e+00 1103.00
IUUC-Psi-093577 Pelodiscus sinensis 36.41 1.00e-110 394.00
IUUC-Pab-098215 Pongo abelii 68.29 7.00e-167 580.00
IUUC-Pca-100883 Procavia capensis 63.01 0.00e+00 741.00
IUUC-Pva-102465 Pteropus vampyrus 66.67 0.00e+00 740.00
IUUC-Rno-105120 Rattus norvegicus 59.20 0.00e+00 954.00
IUUC-Sar-113320 Sorex araneus 58.53 2.00e-85 310.00
IUUC-Ssc-116042 Sus scrofa 65.80 0.00e+00 1043.00
IUUC-Tbe-127880 Tupaia belangeri 63.74 3.00e-130 459.00
Created Date 25-Jun-2017

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