iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSG00000141580.15	ENST00000392325.8	ENSP00000376139.4
ENSG00000141580.15	ENST00000572583.5	ENSP00000461488.1
ENSG00000141580.15	ENST00000576517.1	ENSP00000460297.1
ENSG00000141580.15	ENST00000573616.5	ENSP00000458738.1
ENSG00000141580.15	ENST00000571817.5	ENSP00000461355.1

Annotation

Cancer Mutation
TCGA	ICGC	COSMIC	CGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	TCGA	ICGC
COSMIC	HPM
DNA & RNA Element
UTRdb	AREsite	circRNADb	CircNet
miRTarBase	microRNA	TRANSFAC	TargetScan
RepTar	SomamiR	miRcode	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	HINT
Mentha	InWeb_IM
Disease-associated Variation
ClinVar	OMIM
Post-translational Modifications (PTMs)
CPLM	dbPAF	PhosphositePlus	dbPTM
BioGRID	mUbiSiDa
DNA Methylation
TCGA	ICGC	COSMIC
Protein Expression/Proteomics
THPA	HPM	GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.00e-09	39.1	184	222

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgt.ikvWDlrtgvllk 37
           H++  +c+a+  ++t+++++s  gt i+++D+++g+l++
   Q: 184  HEGVLSCIALnlQGTRIATASEKGTlIRIFDTSSGHLIQ 222
           9999******9777********************99887 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

MNLLPCNPHG NGLLYAGFNQ DHGCFACGME NGFRVYNTDP LKEKEKQEFL EGGVGHVEML 60
FRCNYLALVG GGKKPKYPPN KVMIWDDLKK KTVIEIEFST EVKAVKLRRD RIVVVLDSMI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCTCCATAG GCTCCCTGGT GGGGCGCGGG CGCGCGCACG GACGTCCAGC ACGCACGCAC 60
GCACGTCCAG CACACACGCA CATCCAGCAC GCACGCACGT ACGTCCGGCA CTTCCGGCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

SMART

SM00320--WD40

KEGG

hsa:56270

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000966	Aegilops tauschii	44.23	7.00e-78	284.00
IUUC-Aml-001504	Ailuropoda melanoleuca	99.71	0.00e+00	658.00
IUUC-Atr-002710	Amborella trichopoda	43.51	3.00e-73	268.00
IUUC-Apl-003741	Anas platyrhynchos	98.14	2.00e-174	604.00
IUUC-Aca-004629	Anolis carolinensis	96.51	0.00e+00	643.00
IUUC-Aly-006440	Arabidopsis lyrata	43.07	1.00e-64	240.00
IUUC-Ath-006629	Arabidopsis thaliana	44.21	9.00e-66	244.00
IUUC-Ame-011233	Astyanax mexicanus	95.93	0.00e+00	640.00
IUUC-Bta-012842	Bos taurus	98.84	0.00e+00	657.00
IUUC-Bdi-014739	Brachypodium distachyon	43.96	1.00e-78	286.00
IUUC-Bol-015119	Brassica oleracea	44.41	5.00e-67	248.00
IUUC-Bra-017319	Brassica rapa	44.88	4.00e-67	248.00
IUUC-Cja-018855	Callithrix jacchus	99.68	3.00e-173	600.00
IUUC-Cfa-020539	Canis familiaris	99.68	2.00e-172	597.00
IUUC-Cpo-021981	Cavia porcellus	100.00	0.00e+00	662.00
IUUC-Cre-022613	Chlamydomonas reinhardtii	33.85	5.00e-31	129.00
IUUC-Csa-023140	Chlorocebus sabaeus	100.00	0.00e+00	662.00
IUUC-Cin-025655	Ciona intestinalis	63.96	4.00e-117	414.00
IUUC-Csv-025977	Ciona savignyi	63.66	1.00e-123	436.00
IUUC-Dre-028091	Danio rerio	95.93	0.00e+00	639.00
IUUC-Dno-029987	Dasypus novemcinctus	97.97	0.00e+00	652.00
IUUC-Dme-031881	Drosophila melanogaster	67.93	9.00e-134	469.00
IUUC-Ete-032771	Echinops telfairi	86.64	6.00e-122	429.00
IUUC-Eca-033323	Equus caballus	100.00	2.00e-177	615.00
IUUC-Eeu-034479	Erinaceus europaeus	98.71	8.00e-127	446.00
IUUC-Fca-035675	Felis catus	97.87	3.00e-177	614.00
IUUC-Fal-037218	Ficedula albicollis	97.09	0.00e+00	644.00
IUUC-Fso-038422	Fusarium solani	32.18	6.00e-49	187.00
IUUC-Ggr-039909	Gaeumannomyces graminis	37.80	2.00e-52	199.00
IUUC-Gga-040977	Gallus gallus	97.38	0.00e+00	645.00
IUUC-Gac-042096	Gasterosteus aculeatus	95.35	0.00e+00	659.00
IUUC-Gma-043922	Glycine max	45.85	2.00e-75	276.00
IUUC-Ggo-045466	Gorilla gorilla	80.52	3.00e-147	514.00
IUUC-Hvu-047851	Hordeum vulgare	44.23	5.00e-78	284.00
IUUC-Itr-048277	Ictidomys tridecemlineatus	99.71	0.00e+00	661.00
IUUC-Lch-049800	Latimeria chalumnae	95.64	0.00e+00	640.00
IUUC-Lpe-051205	Leersia perrieri	44.93	6.00e-78	284.00
IUUC-Loc-052379	Lepisosteus oculatus	97.20	5.00e-173	600.00
IUUC-Laf-054084	Loxodonta africana	93.23	5.00e-171	593.00
IUUC-Mcc-055304	Macaca mulatta	100.00	2.00e-173	601.00
IUUC-Meu-056020	Macropus eugenii	87.70	5.00e-141	493.00
IUUC-Mpo-057416	Magnaporthe poae	39.37	5.00e-54	205.00
IUUC-Mtr-058609	Medicago truncatula	45.29	3.00e-65	242.00
IUUC-Mla-058885	Melampsora laricipopulina	37.50	1.00e-37	149.00
IUUC-Mga-060051	Meleagris gallopavo	96.08	3.00e-176	610.00
IUUC-Mmr-061076	Microcebus murinus	91.91	4.00e-171	593.00
IUUC-Mdo-062465	Monodelphis domestica	98.55	0.00e+00	653.00
IUUC-Mmu-063289	Mus musculus	99.13	0.00e+00	656.00
IUUC-Mac-064838	Musa acuminata	42.43	2.00e-75	276.00
IUUC-Mpu-066052	Mustela putorius furo	98.76	4.00e-176	610.00
IUUC-Mlu-067972	Myotis lucifugus	99.71	0.00e+00	660.00
IUUC-Nfi-068596	Neosartorya fischeri	36.07	5.00e-54	204.00
IUUC-Nle-069047	Nomascus leucogenys	100.00	1.00e-176	611.00
IUUC-Ont-071875	Oreochromis niloticus	95.93	0.00e+00	663.00
IUUC-Ocu-074736	Oryctolagus cuniculus	91.19	5.00e-162	563.00
IUUC-Oba-075827	Oryza barthii	44.23	4.00e-78	285.00
IUUC-Obr-076476	Oryza brachyantha	43.96	9.00e-78	283.00
IUUC-Ogl-077630	Oryza glaberrima	44.23	4.00e-78	285.00
IUUC-Ogu-078126	Oryza glumaepatula	44.51	2.00e-78	286.00
IUUC-Oin-080115	Oryza indica	44.23	4.00e-78	285.00
IUUC-Olo-080657	Oryza longistaminata	45.66	6.00e-77	283.00
IUUC-Ome-081702	Oryza meridionalis	45.72	5.00e-75	275.00
IUUC-Oni-082884	Oryza nivara	44.93	6.00e-78	285.00
IUUC-Opu-083460	Oryza punctata	44.93	2.00e-77	284.00
IUUC-Oru-084193	Oryza rufipogon	44.23	4.00e-78	285.00
IUUC-Osa-085948	Oryza sativa	44.23	4.00e-78	285.00
IUUC-Ola-086628	Oryzias latipes	94.77	0.00e+00	658.00
IUUC-Olu-087808	Ostreococcus lucimarinus	41.57	5.00e-72	264.00
IUUC-Oga-088642	Otolemur garnettii	100.00	0.00e+00	662.00
IUUC-Oar-089538	Ovis aries	93.91	6.00e-177	613.00
IUUC-Ptr-091326	Pan troglodytes	100.00	0.00e+00	662.00
IUUC-Pan-091795	Papio anubis	100.00	0.00e+00	662.00
IUUC-Psi-093258	Pelodiscus sinensis	97.83	1.00e-174	605.00
IUUC-Pno-094851	Phaeosphaeria nodorum	34.08	2.00e-44	173.00
IUUC-Ppa-095480	Physcomitrella patens	43.42	7.00e-71	261.00
IUUC-Pfo-096099	Poecilia formosa	95.64	0.00e+00	662.00
IUUC-Pab-098681	Pongo abelii	100.00	0.00e+00	662.00
IUUC-Pop-099760	Populus trichocarpa	44.89	1.00e-77	283.00
IUUC-Ppe-101963	Prunus persica	45.40	6.00e-66	244.00
IUUC-Pva-103006	Pteropus vampyrus	99.38	6.00e-176	609.00
IUUC-Pgr-103258	Puccinia graminis	36.08	1.00e-40	161.00
IUUC-Ptt-103915	Puccinia triticina	34.63	4.00e-38	152.00
IUUC-Pte-104115	Pyrenophora teres	35.05	5.00e-46	178.00
IUUC-Rno-106112	Rattus norvegicus	99.13	0.00e+00	656.00
IUUC-Sce-106327	Saccharomyces cerevisiae	29.58	2.00e-35	143.00
IUUC-Sha-107573	Sarcophilus harrisii	98.26	0.00e+00	652.00
IUUC-Sja-107791	Schizosaccharomyces japonicus	34.78	2.00e-44	172.00
IUUC-Spo-108254	Schizosaccharomyces pombe	34.16	5.00e-41	161.00
IUUC-Smo-109446	Selaginella moellendorffii	43.21	2.00e-81	296.00
IUUC-Sit-110095	Setaria italica	43.96	4.00e-78	285.00
IUUC-Sly-111030	Solanum lycopersicum	40.77	1.00e-70	259.00
IUUC-Stu-111954	Solanum tuberosum	44.12	1.00e-66	247.00
IUUC-Sar-113276	Sorex araneus	88.05	3.00e-109	387.00
IUUC-Sbi-114020	Sorghum bicolor	43.41	1.00e-77	283.00
IUUC-Ssc-116163	Sus scrofa	98.55	0.00e+00	658.00
IUUC-Tgu-116488	Taeniopygia guttata	97.52	8.00e-173	599.00
IUUC-Tru-118329	Takifugu rubripes	95.06	0.00e+00	689.00
IUUC-Tni-119729	Tetraodon nigroviridis	87.39	0.00e+00	634.00
IUUC-Tca-121459	Theobroma cacao	44.69	4.00e-61	228.00
IUUC-Tre-122255	Trichoderma reesei	32.97	4.00e-51	195.00
IUUC-Tvi-122643	Trichoderma virens	34.77	9.00e-56	210.00
IUUC-Tae-123911	Triticum aestivum	44.23	3.00e-78	285.00
IUUC-Tur-126757	Triticum urartu	43.96	5.00e-78	284.00
IUUC-Ttr-128940	Tursiops truncatus	98.99	7.00e-160	556.00
IUUC-Vda-129980	Verticillium dahliae	30.33	1.00e-42	166.00
IUUC-Vvi-131053	Vitis vinifera	45.69	4.00e-76	278.00
IUUC-Xtr-131806	Xenopus tropicalis	97.09	0.00e+00	646.00
IUUC-Xma-134275	Xiphophorus maculatus	95.64	0.00e+00	662.00
IUUC-Yli-134566	Yarrowia lipolytica	33.91	1.00e-58	220.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence