iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	TRANSFAC	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
CPLM	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E2/Other	98.20	8.00e-96	346.00	IUUC-Hsa-046948

Active Site

Position(s)	Description	Evidence
116	Glycyl thioester intermediate	{ECO:0000250}

Organism

Rattus norvegicus

Functional Description
(View)

E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage.

Protein Sequence
(Fasta)

MADEATRRVV SEIPVLKTNA GPRDRELWVQ RLKEEYQSLI RYVENNKNAD NDWFRLESNK 60
EGTRWFGKCW YIHDFLKYEF DIEFEIPITY PTTAPEIAVP ELDGKTAKMY RGGKICLTDH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTGAACAGA GTAACCCACC TCCATTCTGT TCTTCGGACG CTTGCGCCAG TGGGTCAATT 60
TTATTTTCTT TCAAAAATAA AAGTCGAGTG CATTCAGAGA CGGCCTTAAG GCAATACGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR016135--UBQ-conjugating_enzyme/RWD
IPR014806--Ufc1

Pfam

PF08694--UFC1

Gene Ontology

GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0071568--F:UFM1 transferase activity
GO:1990592--P:protein K69-linked ufmylation
GO:0071569--P:protein ufmylation
GO:0034976--P:response to endoplasmic reticulum stress

KEGG

rno:445268

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000219	Aegilops tauschii	68.35	3.00e-30	123.00
IUUC-Aml-001773	Ailuropoda melanoleuca	95.81	2.00e-95	340.00
IUUC-Atr-002519	Amborella trichopoda	65.22	5.00e-67	246.00
IUUC-Aca-004597	Anolis carolinensis	87.20	6.00e-87	312.00
IUUC-Aly-005549	Arabidopsis lyrata	64.81	5.00e-65	239.00
IUUC-Ath-007416	Arabidopsis thaliana	64.81	5.00e-65	239.00
IUUC-Ame-011281	Astyanax mexicanus	85.54	4.00e-86	309.00
IUUC-Bta-012940	Bos taurus	97.60	1.00e-96	344.00
IUUC-Bdi-014987	Brachypodium distachyon	62.35	2.00e-61	227.00
IUUC-Bol-016532	Brassica oleracea	64.20	4.00e-65	239.00
IUUC-Bra-017971	Brassica rapa	64.20	3.00e-65	240.00
IUUC-Cel-018620	Caenorhabditis elegans	70.62	5.00e-71	259.00
IUUC-Cja-019762	Callithrix jacchus	98.19	2.00e-96	343.00
IUUC-Cfa-021172	Canis familiaris	97.01	2.00e-96	344.00
IUUC-Cpo-021575	Cavia porcellus	97.60	2.00e-96	343.00
IUUC-Cre-022894	Chlamydomonas reinhardtii	60.00	2.00e-59	221.00
IUUC-Csa-024240	Chlorocebus sabaeus	94.01	1.00e-92	331.00
IUUC-Cho-024457	Choloepus hoffmanni	98.18	6.00e-29	120.00
IUUC-Cin-025708	Ciona intestinalis	75.61	5.00e-76	276.00
IUUC-Csv-026307	Ciona savignyi	76.22	2.00e-76	277.00
IUUC-Cgl-026671	Colletotrichum gloeosporioides	23.40	1.40e-01	30.00
IUUC-Dre-027752	Danio rerio	85.98	6.00e-87	312.00
IUUC-Dno-028957	Dasypus novemcinctus	96.50	2.00e-81	294.00
IUUC-Dor-030637	Dipodomys ordii	97.60	1.00e-96	344.00
IUUC-Dme-032033	Drosophila melanogaster	77.44	3.00e-80	290.00
IUUC-Ete-033056	Echinops telfairi	95.21	9.00e-95	338.00
IUUC-Eca-034260	Equus caballus	98.20	4.00e-97	346.00
IUUC-Eeu-034785	Erinaceus europaeus	60.00	9.00e-20	88.20
IUUC-Fca-035879	Felis catus	97.59	4.00e-95	339.00
IUUC-Gmo-039023	Gadus morhua	80.98	7.00e-84	302.00
IUUC-Gga-040475	Gallus gallus	83.33	5.00e-73	266.00
IUUC-Gac-041574	Gasterosteus aculeatus	76.83	6.00e-78	282.00
IUUC-Gma-043338	Glycine max	62.96	9.00e-65	239.00
IUUC-Ggo-044713	Gorilla gorilla	96.06	3.00e-72	263.00
IUUC-Hsa-046948	Homo sapiens	98.20	4.00e-97	346.00
IUUC-Hvu-047147	Hordeum vulgare	62.73	6.00e-61	226.00
IUUC-Itr-048742	Ictidomys tridecemlineatus	98.20	4.00e-97	346.00
IUUC-Lch-049654	Latimeria chalumnae	85.63	6.00e-88	315.00
IUUC-Lpe-051422	Leersia perrieri	62.73	2.00e-61	228.00
IUUC-Loc-051920	Lepisosteus oculatus	87.80	2.00e-88	317.00
IUUC-Laf-054338	Loxodonta africana	98.20	4.00e-97	346.00
IUUC-Mcc-054927	Macaca mulatta	98.20	4.00e-97	346.00
IUUC-Meu-056831	Macropus eugenii	94.51	2.00e-92	330.00
IUUC-Mtr-058091	Medicago truncatula	63.58	2.00e-64	237.00
IUUC-Mga-059933	Meleagris gallopavo	75.76	2.00e-44	170.00
IUUC-Mmr-061433	Microcebus murinus	97.01	2.00e-96	344.00
IUUC-Mdo-061994	Monodelphis domestica	93.90	1.00e-91	328.00
IUUC-Mmu-063398	Mus musculus	98.80	1.00e-97	348.00
IUUC-Mac-064536	Musa acuminata	61.73	1.00e-62	231.00
IUUC-Mpu-066795	Mustela putorius furo	97.60	1.00e-96	344.00
IUUC-Mlu-067983	Myotis lucifugus	95.81	9.00e-95	338.00
IUUC-Nle-069720	Nomascus leucogenys	98.20	4.00e-62	228.00
IUUC-Opr-070723	Ochotona princeps	97.60	1.00e-96	344.00
IUUC-Ont-071509	Oreochromis niloticus	78.66	1.00e-79	288.00
IUUC-Oan-073541	Ornithorhynchus anatinus	85.11	7.00e-22	94.70
IUUC-Ocu-074044	Oryctolagus cuniculus	98.17	7.00e-95	338.00
IUUC-Oba-075612	Oryza barthii	62.35	2.00e-61	228.00
IUUC-Obr-076432	Oryza brachyantha	62.35	2.00e-61	228.00
IUUC-Ogl-077071	Oryza glaberrima	62.35	2.00e-61	228.00
IUUC-Ogu-078427	Oryza glumaepatula	62.35	2.00e-61	228.00
IUUC-Oin-079963	Oryza indica	62.35	2.00e-61	228.00
IUUC-Olo-080455	Oryza longistaminata	62.35	2.00e-61	228.00
IUUC-Oni-082562	Oryza nivara	62.35	2.00e-61	228.00
IUUC-Opu-083688	Oryza punctata	62.11	6.00e-61	227.00
IUUC-Oru-084472	Oryza rufipogon	62.35	2.00e-61	228.00
IUUC-Osa-085623	Oryza sativa	62.35	2.00e-61	228.00
IUUC-Oga-088366	Otolemur garnettii	98.20	4.00e-97	346.00
IUUC-Oar-089754	Ovis aries	97.01	4.00e-96	343.00
IUUC-Ptr-090679	Pan troglodytes	97.60	8.00e-97	345.00
IUUC-Psi-093472	Pelodiscus sinensis	90.32	4.00e-67	246.00
IUUC-Ppa-095568	Physcomitrella patens	67.28	7.00e-68	249.00
IUUC-Pfo-097314	Poecilia formosa	78.05	1.00e-78	285.00
IUUC-Pab-098562	Pongo abelii	97.60	1.00e-96	344.00
IUUC-Pop-099506	Populus trichocarpa	63.58	1.00e-64	238.00
IUUC-Pca-101030	Procavia capensis	87.95	3.00e-84	303.00
IUUC-Ppe-101757	Prunus persica	62.96	1.00e-64	238.00
IUUC-Pva-102948	Pteropus vampyrus	97.01	3.00e-96	343.00
IUUC-Sha-107297	Sarcophilus harrisii	93.41	2.00e-93	334.00
IUUC-Sit-110317	Setaria italica	61.73	1.00e-60	225.00
IUUC-Sly-111332	Solanum lycopersicum	62.96	3.00e-64	237.00
IUUC-Stu-112719	Solanum tuberosum	62.96	3.00e-64	237.00
IUUC-Sbi-114869	Sorghum bicolor	61.73	1.00e-60	225.00
IUUC-Ssc-116009	Sus scrofa	98.20	4.00e-97	346.00
IUUC-Tru-117527	Takifugu rubripes	80.49	6.00e-81	292.00
IUUC-Tsy-119195	Tarsius syrichta	93.62	1.00e-75	274.00
IUUC-Tni-120417	Tetraodon nigroviridis	78.66	8.00e-80	288.00
IUUC-Tca-120972	Theobroma cacao	64.20	5.00e-65	239.00
IUUC-Tae-124763	Triticum aestivum	62.73	1.00e-60	225.00
IUUC-Tur-126831	Triticum urartu	62.73	6.00e-61	226.00
IUUC-Tbe-128019	Tupaia belangeri	98.58	3.00e-81	293.00
IUUC-Ttr-129013	Tursiops truncatus	97.60	1.00e-96	344.00
IUUC-Vvi-131214	Vitis vinifera	62.96	8.00e-64	235.00
IUUC-Xtr-132182	Xenopus tropicalis	86.59	2.00e-87	314.00
IUUC-Xma-133877	Xiphophorus maculatus	78.05	1.00e-78	284.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence