iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-061807

UUCD1 version

UUC-MoD-01128

Ensembl Protein ID

ENSMODP00000006496.3

UniProt Accession

F7GGQ0; F7GGQ0_MONDO

Protein Name

Uncharacterized protein

Gene Name

USP21

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000005267.3	ENSMODT00000006631.3	ENSMODP00000006496.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.20e-90	302.9	289	634

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgy 87
           +Gl+NlgNtC++N+vLQcLs++++lr+++l+  ++ +++      +++el++++++++ +lw  ++ +av+p+++ ++++k+ ++fsgy
   Q: 289  VGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRrDFRLEVPSG--GRTQQELTEAFADVLGALWhPDSCEAVNPTRFRTVFQKYVPSFSGY 375
           6******************************5555555554..7899***************888899********************* PP
   S: 88   eqqDaqEflaflldqleeelkk..................eknkpkeeeeeedkselsde..................aeekkkkknks 140
           +qqDaqEfl+ l+++l+ e+++                  +                                      +++   +++s
   Q: 376  SQQDAQEFLKLLMERLHLEINRrgrrappiltdtpapslpR------------------RggalleepelsdddqanlMWKRYLDREDS 446
           ********************996666666666555555544..................3444444444444455555*********** PP
   S: 141  lisdlFqgqlksqikclecdnvssreepfldlslpvpgkeet.kkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPe 228
            i+dlF gqlks +kc++c+ +s+++e f+dlslp+p+k     k sl+dc++ ftkeeele+en+  c++c+++++++kkl+++++P+
   Q: 447  KIVDLFVGQLKSCLKCQACGYRSTTFEVFCDLSLPIPKKGFAgGKVSLRDCFSLFTKEEELESENAPVCDRCRQRTRSTKKLTVQRFPR 535
           *************************************887541456******************************************* PP
   S: 229  vLilhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVte 316
           +L+lhL+Rf  s +++s +k +  v+fpl+ L+l  f +++      +  Y+L+a ++HsGs++ GHY+a+++  + +W  ++Ds+V++
   Q: 536  ILVLHLNRF--SASRGSIKKSSVGVDFPLQrLSLGDFASDKAG----SPVYQLYALCNHSGSVHYGHYTALCRG-QTGWHVYNDSRVSP 617
           *********..55668999**********99*******99543....78************************9.777*********** PP
   S: 317  vkeeevleetgstaYvlfYk 336
           v+e++v +   s++YvlfY+
   Q: 618  VSENQVAS---SEGYVLFYQ 634
           ********...********8 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MLRCAGALFP GEARAQAPGG RNKDGGGACG GSGLGGGRAS SRARGGGSLG QEGVALNWGP 60
GPPGSLSPCW GQGLSRVSTM PQASEHRLGR AREQPISVQP RVGTKLPIGS RARSKERRSP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCCAGAACC AAGAACAGCC TTCTGGACAA CAAGGAAGAC ATCAGATTTC TGCTCACCTG 60
ACTTTGAAGG GTCACTCCTC AAAGGTGATA GATGTGGCAT GAGACATGAA TAGACTTACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0019784--F:NEDD8-specific protease activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001858	Ailuropoda melanoleuca	90.64	0.00e+00	910.00
IUUC-Aca-004612	Anolis carolinensis	58.72	4.00e-174	604.00
IUUC-Ame-011548	Astyanax mexicanus	53.24	5.00e-106	377.00
IUUC-Bta-012626	Bos taurus	90.46	0.00e+00	874.00
IUUC-Cja-018853	Callithrix jacchus	89.93	0.00e+00	909.00
IUUC-Cfa-021167	Canis familiaris	91.17	0.00e+00	895.00
IUUC-Cpo-021305	Cavia porcellus	87.48	0.00e+00	874.00
IUUC-Csa-023454	Chlorocebus sabaeus	90.28	0.00e+00	915.00
IUUC-Cho-024836	Choloepus hoffmanni	94.82	8.00e-106	376.00
IUUC-Dre-028454	Danio rerio	54.06	4.00e-109	388.00
IUUC-Dno-029955	Dasypus novemcinctus	82.86	3.00e-156	545.00
IUUC-Dor-031053	Dipodomys ordii	90.81	0.00e+00	945.00
IUUC-Ete-032416	Echinops telfairi	93.63	3.00e-141	495.00
IUUC-Eca-033817	Equus caballus	89.75	0.00e+00	907.00
IUUC-Fca-036400	Felis catus	87.23	0.00e+00	903.00
IUUC-Gmo-038926	Gadus morhua	51.29	3.00e-104	372.00
IUUC-Gac-041331	Gasterosteus aculeatus	53.44	1.00e-107	383.00
IUUC-Ggo-045174	Gorilla gorilla	90.28	0.00e+00	915.00
IUUC-Hsa-046443	Homo sapiens	90.11	0.00e+00	913.00
IUUC-Itr-048329	Ictidomys tridecemlineatus	89.46	0.00e+00	899.00
IUUC-Lch-050539	Latimeria chalumnae	41.01	2.00e-110	393.00
IUUC-Loc-051808	Lepisosteus oculatus	55.40	1.00e-115	409.00
IUUC-Laf-053730	Loxodonta africana	88.75	0.00e+00	913.00
IUUC-Mcc-055541	Macaca mulatta	90.28	0.00e+00	915.00
IUUC-Meu-056279	Macropus eugenii	97.16	0.00e+00	1016.00
IUUC-Mmr-060913	Microcebus murinus	90.81	0.00e+00	872.00
IUUC-Mmu-063599	Mus musculus	89.65	0.00e+00	886.00
IUUC-Mpu-066329	Mustela putorius furo	91.34	0.00e+00	895.00
IUUC-Mlu-067359	Myotis lucifugus	87.62	0.00e+00	796.00
IUUC-Nle-068975	Nomascus leucogenys	88.16	0.00e+00	887.00
IUUC-Opr-071096	Ochotona princeps	88.16	0.00e+00	855.00
IUUC-Ocu-074228	Oryctolagus cuniculus	90.51	0.00e+00	885.00
IUUC-Ola-086684	Oryzias latipes	47.10	3.00e-101	362.00
IUUC-Oga-088007	Otolemur garnettii	73.90	0.00e+00	704.00
IUUC-Oar-090226	Ovis aries	89.58	0.00e+00	673.00
IUUC-Ptr-091522	Pan troglodytes	90.28	0.00e+00	915.00
IUUC-Pan-091954	Papio anubis	89.93	0.00e+00	907.00
IUUC-Psi-093216	Pelodiscus sinensis	59.94	0.00e+00	684.00
IUUC-Pfo-096257	Poecilia formosa	49.86	2.00e-102	365.00
IUUC-Pab-098691	Pongo abelii	90.11	0.00e+00	914.00
IUUC-Pca-101133	Procavia capensis	82.69	0.00e+00	850.00
IUUC-Pva-102681	Pteropus vampyrus	87.99	0.00e+00	843.00
IUUC-Rno-105132	Rattus norvegicus	89.93	0.00e+00	894.00
IUUC-Sha-107145	Sarcophilus harrisii	97.38	0.00e+00	924.00
IUUC-Ssc-115586	Sus scrofa	91.17	0.00e+00	874.00
IUUC-Tgu-117491	Taeniopygia guttata	81.07	7.00e-114	402.00
IUUC-Tni-120746	Tetraodon nigroviridis	50.89	2.00e-94	338.00
IUUC-Tbe-127465	Tupaia belangeri	96.74	8.00e-124	437.00
IUUC-Ttr-128274	Tursiops truncatus	88.69	0.00e+00	857.00
IUUC-Xtr-131989	Xenopus tropicalis	48.54	3.00e-124	438.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence