iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066329

Ensembl Protein ID

ENSMPUP00000014153.1

UniProt Accession

M3YS43; M3YS43_MUSPF

Genbank Protein ID

ENSMPUP00000014153

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01088007

Gene Name

USP21

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000014261.1	ENSMPUT00000014379.1	ENSMPUP00000014153.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.20e-91	306.0	212	556

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgy 87
           +Gl+NlgNtC++N+vLQcLs++++lr+++l+  ++++++     ++ +el++++++++ +lw  ++ +av+p+++ ++++k+ ++fsgy
   Q: 212  VGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRrDFRQEVPG---GGRAQELTEAFADVIGALWhPDSCEAVNPTRFRAVFQKYVPSFSGY 297
           6******************************667777776...5789***************888899********************* PP
   S: 88   eqqDaqEflaflldqleeelkk..................eknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikcle 158
           +qqDaqEfl+ l+++l+ e+++                  ++     ee e ++ ++ +  +++  ++++s i+dlF gqlks +kc++
   Q: 298  SQQDAQEFLKLLMERLHLEINRrgrrappilasspapsqpRRGGALLEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQA 386
           ********************9988777777776665544444444444444444444555***************************** PP
   S: 159  cdnvssreepfldlslpvpgkeet.kkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksr 246
           c+ +s+++e f+dlslp+p+k     k sl+dc++ ftkeeele+en+  c++c++k++++kkl+++++P++L+lhL+Rf  s +++s 
   Q: 387  CGYRSTTFEVFCDLSLPIPKKGFAgGKVSLRDCFSLFTKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRF--SASRGSI 473
           *******************887541456****************************************************..5566899 PP
   S: 247  ekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlf 334
           +k +  v+fpl+ L+l  f +++      +  Y+L+a ++HsGs++ GHY+a+++  + +W  ++Ds+V++v+e++v +   s++Yvlf
   Q: 474  KKSSVGVDFPLQrLSLGDFASDKAG----SPVYQLYALCNHSGSVHYGHYTALCRC-QTGWHVYNDSRVSPVSENQVAS---SEGYVLF 554
           9**********99*******99543....78*************************.777*******************...******* PP
   S: 335  Yk 336
           Y+
   Q: 555  YQ 556
           *8 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MPQASEHRLG RTREPPVNVQ PRVGSKLPFA PRARSKERRN PAPGPNPMLR PLPPRPGPPE 60
ERLKKLELGR GRTSGPRPRG PLRADHGVPL PGSPPPTVAL PLPSRTNLAR SKSVSSGDLR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCCAGCCTG TGGTGTCCAC AATGCCCCAG GCCTCTGAGC ACCGCCTGGG CCGGACCCGA 60
GAGCCACCTG TTAATGTCCA GCCCCGAGTG GGGTCCAAGC TACCATTTGC CCCGAGGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0019784--F:NEDD8-specific protease activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001858	Ailuropoda melanoleuca	99.12	0.00e+00	1023.00
IUUC-Aca-004612	Anolis carolinensis	59.67	1.00e-174	605.00
IUUC-Ame-011548	Astyanax mexicanus	51.98	7.00e-104	370.00
IUUC-Bta-012626	Bos taurus	97.88	0.00e+00	982.00
IUUC-Cja-018853	Callithrix jacchus	97.35	0.00e+00	1020.00
IUUC-Cfa-021167	Canis familiaris	99.65	0.00e+00	1004.00
IUUC-Cpo-021305	Cavia porcellus	96.11	0.00e+00	949.00
IUUC-Csa-023454	Chlorocebus sabaeus	97.52	0.00e+00	1023.00
IUUC-Cho-024836	Choloepus hoffmanni	96.37	2.00e-108	385.00
IUUC-Dre-028454	Danio rerio	53.52	3.00e-108	384.00
IUUC-Dno-029955	Dasypus novemcinctus	93.49	0.00e+00	650.00
IUUC-Dor-031053	Dipodomys ordii	96.81	0.00e+00	1043.00
IUUC-Ete-032416	Echinops telfairi	95.88	4.00e-145	508.00
IUUC-Eca-033817	Equus caballus	96.99	0.00e+00	1009.00
IUUC-Fca-036400	Felis catus	98.06	0.00e+00	996.00
IUUC-Gmo-038926	Gadus morhua	54.80	1.00e-104	372.00
IUUC-Gac-041331	Gasterosteus aculeatus	53.59	2.00e-108	385.00
IUUC-Ggo-045174	Gorilla gorilla	97.52	0.00e+00	1023.00
IUUC-Hsa-046443	Homo sapiens	97.35	0.00e+00	1024.00
IUUC-Itr-048329	Ictidomys tridecemlineatus	96.83	0.00e+00	1003.00
IUUC-Lch-050539	Latimeria chalumnae	62.00	9.00e-106	377.00
IUUC-Loc-051808	Lepisosteus oculatus	55.83	1.00e-116	412.00
IUUC-Laf-053730	Loxodonta africana	95.60	0.00e+00	1013.00
IUUC-Mcc-055541	Macaca mulatta	97.52	0.00e+00	1023.00
IUUC-Meu-056279	Macropus eugenii	91.34	0.00e+00	970.00
IUUC-Mmr-060913	Microcebus murinus	97.70	0.00e+00	951.00
IUUC-Mdo-061807	Monodelphis domestica	91.34	0.00e+00	898.00
IUUC-Mmu-063599	Mus musculus	95.96	0.00e+00	964.00
IUUC-Mlu-067359	Myotis lucifugus	94.85	0.00e+00	891.00
IUUC-Nle-068975	Nomascus leucogenys	95.22	0.00e+00	991.00
IUUC-Opr-071096	Ochotona princeps	94.16	0.00e+00	951.00
IUUC-Ocu-074228	Oryctolagus cuniculus	96.65	0.00e+00	983.00
IUUC-Ola-086684	Oryzias latipes	50.71	3.00e-102	365.00
IUUC-Oga-088007	Otolemur garnettii	79.15	0.00e+00	771.00
IUUC-Oar-090226	Ovis aries	97.39	0.00e+00	770.00
IUUC-Ptr-091522	Pan troglodytes	97.52	0.00e+00	1023.00
IUUC-Pan-091954	Papio anubis	97.17	0.00e+00	1016.00
IUUC-Psi-093216	Pelodiscus sinensis	60.00	0.00e+00	671.00
IUUC-Pfo-096257	Poecilia formosa	50.42	3.00e-102	365.00
IUUC-Pab-098691	Pongo abelii	97.35	0.00e+00	1022.00
IUUC-Pca-101133	Procavia capensis	89.20	0.00e+00	953.00
IUUC-Pva-102681	Pteropus vampyrus	95.04	0.00e+00	944.00
IUUC-Rno-105132	Rattus norvegicus	96.64	0.00e+00	996.00
IUUC-Sha-107145	Sarcophilus harrisii	91.06	0.00e+00	883.00
IUUC-Ssc-115586	Sus scrofa	99.12	0.00e+00	981.00
IUUC-Tgu-117491	Taeniopygia guttata	81.48	4.00e-114	403.00
IUUC-Tni-120746	Tetraodon nigroviridis	51.64	8.00e-96	343.00
IUUC-Tbe-127465	Tupaia belangeri	99.07	6.00e-127	447.00
IUUC-Ttr-128274	Tursiops truncatus	96.11	0.00e+00	964.00
IUUC-Xtr-131989	Xenopus tropicalis	49.14	4.00e-126	444.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence