iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-107145

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01174737

Gene Name

USP21

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000016472.1	ENSSHAT00000019551.1	ENSSHAP00000019394.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.50e-81	274.4	210	534

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgy 87
           +Gl+NlgNtC++N+vLQcLs++++lr+++l+  ++++++       ++el++++++++ +lw  ++ +av+p+++ ++++k+ ++fsgy
   Q: 210  VGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRrDFRQEVPGG--GRAHQELTEAFADVLGALWhPDSCEAVNPTRFRTVFQKYVPSFSGY 296
           6******************************7888899887..6799***************888899********************* PP
   S: 88   eqqDaqEflaflldqleeelkk..................eknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikcle 158
           +qqDaqEfl+ l+++l+ e+++                  ++     ee e ++ e+ +  +++   +++s i+dlF gqlks +kc++
   Q: 297  SQQDAQEFLKLLMERLHLEINRrgrrappiladtpapslpRRGGALLEEPELSDDERANLMWKRYLDREDSKIVDLFVGQLKSCLKCQA 385
           ********************9988888888888887777766666667777777777777***************************** PP
   S: 159  cdnvssreepfldlslpvpgkeet.kkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksr 246
           c+ +s+++e f+dlslp+p+k     k sl+dc++ ftkeeele+en+  c++c+++++++kkl+++++P++L+lhL+Rf  s +++s 
   Q: 386  CGYRSTTFEVFCDLSLPIPKKGFAgGKVSLRDCFSLFTKEEELESENAPVCDRCRQRTRSTKKLTVQRFPRILVLHLNRF--SASRGSI 472
           *******************887541456****************************************************..5566899 PP
   S: 247  ekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgkWllfdDs 312
           +k +  v+fpl+ L+l  f +++      +  Y+L+a ++HsGs++ GHY+a+++  + +W  ++Ds
   Q: 473  KKSSVGVDFPLQrLSLGDFASDKAG----SPVYQLYALCNHSGSVHYGHYTALCRG-QTGWHVYNDS 534
           9**********99*******99543....78************************9.777******8 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MPQASEHRLG RAREQPIGVQ PRVGAKLPIG SRARSKERRS PVPAPNPMLR PLPPRPGPPE 60
ERFKKLELGR GRSSAPRPRG PPRADHGVPL PGSPPPAVAL PLPTRTNLAR SKSVSSGDLR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CATGGCACCC ACCGCGGGAC GCAAGGGGCG GGACGACGCC AGCGCCACGA AGGAGGCGGT 60
CCGAGCGAAT GCTGCGCTGC GCAGGCGCCC TTGTTCCCGG TGAAGCTCGG GCCCGGGCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0019784--F:NEDD8-specific protease activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

shr:100922218

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001858	Ailuropoda melanoleuca	90.32	0.00e+00	854.00
IUUC-Aca-004612	Anolis carolinensis	57.71	3.00e-162	565.00
IUUC-Ame-011548	Astyanax mexicanus	53.15	2.00e-98	352.00
IUUC-Bta-012626	Bos taurus	90.13	0.00e+00	820.00
IUUC-Cja-018853	Callithrix jacchus	89.57	0.00e+00	852.00
IUUC-Cfa-021167	Canis familiaris	90.88	0.00e+00	838.00
IUUC-Cpo-021305	Cavia porcellus	87.17	0.00e+00	820.00
IUUC-Csa-023454	Chlorocebus sabaeus	89.94	0.00e+00	857.00
IUUC-Cho-024836	Choloepus hoffmanni	95.09	2.00e-90	325.00
IUUC-Dre-028454	Danio rerio	55.22	2.00e-103	369.00
IUUC-Dno-029955	Dasypus novemcinctus	82.86	2.00e-156	545.00
IUUC-Dor-031053	Dipodomys ordii	90.13	0.00e+00	885.00
IUUC-Ete-032416	Echinops telfairi	93.70	2.00e-124	439.00
IUUC-Eca-033817	Equus caballus	89.57	0.00e+00	851.00
IUUC-Fca-036400	Felis catus	88.87	0.00e+00	833.00
IUUC-Gmo-038926	Gadus morhua	53.87	5.00e-96	344.00
IUUC-Gac-041331	Gasterosteus aculeatus	52.92	5.00e-99	354.00
IUUC-Ggo-045174	Gorilla gorilla	89.94	0.00e+00	857.00
IUUC-Hsa-046443	Homo sapiens	89.76	0.00e+00	858.00
IUUC-Itr-048329	Ictidomys tridecemlineatus	89.44	0.00e+00	848.00
IUUC-Lch-050539	Latimeria chalumnae	62.01	4.00e-97	348.00
IUUC-Loc-051808	Lepisosteus oculatus	55.88	1.00e-108	386.00
IUUC-Laf-053730	Loxodonta africana	88.33	0.00e+00	857.00
IUUC-Mcc-055541	Macaca mulatta	89.94	0.00e+00	857.00
IUUC-Meu-056279	Macropus eugenii	98.32	0.00e+00	971.00
IUUC-Mmr-060913	Microcebus murinus	90.50	0.00e+00	816.00
IUUC-Mdo-061807	Monodelphis domestica	97.38	0.00e+00	908.00
IUUC-Mmu-063599	Mus musculus	89.46	0.00e+00	834.00
IUUC-Mpu-066329	Mustela putorius furo	91.06	0.00e+00	838.00
IUUC-Mlu-067359	Myotis lucifugus	88.00	0.00e+00	796.00
IUUC-Nle-068975	Nomascus leucogenys	88.08	0.00e+00	836.00
IUUC-Opr-071096	Ochotona princeps	87.52	0.00e+00	800.00
IUUC-Ocu-074228	Oryctolagus cuniculus	90.19	0.00e+00	829.00
IUUC-Ola-086684	Oryzias latipes	49.85	7.00e-94	337.00
IUUC-Oga-088007	Otolemur garnettii	72.30	0.00e+00	645.00
IUUC-Oar-090226	Ovis aries	89.58	0.00e+00	674.00
IUUC-Ptr-091522	Pan troglodytes	89.94	0.00e+00	857.00
IUUC-Pan-091954	Papio anubis	89.76	0.00e+00	857.00
IUUC-Psi-093216	Pelodiscus sinensis	59.31	0.00e+00	644.00
IUUC-Pfo-096257	Poecilia formosa	50.44	3.00e-97	348.00
IUUC-Pab-098691	Pongo abelii	89.76	0.00e+00	856.00
IUUC-Pca-101133	Procavia capensis	81.56	0.00e+00	787.00
IUUC-Pva-102681	Pteropus vampyrus	87.34	0.00e+00	785.00
IUUC-Rno-105132	Rattus norvegicus	89.76	0.00e+00	843.00
IUUC-Ssc-115586	Sus scrofa	90.88	0.00e+00	815.00
IUUC-Tgu-117491	Taeniopygia guttata	82.72	6.00e-116	409.00
IUUC-Tni-120746	Tetraodon nigroviridis	51.49	2.00e-95	342.00
IUUC-Tbe-127465	Tupaia belangeri	96.77	8.00e-107	380.00
IUUC-Ttr-128274	Tursiops truncatus	88.45	0.00e+00	803.00
IUUC-Xtr-131989	Xenopus tropicalis	48.22	3.00e-115	408.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence