iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089789

Ensembl Protein ID

ENSOARP00000011273.1

UniProt Accession

W5PLF0; W5PLF0_SHEEP

Genbank Protein ID

ENSOARP00000011273

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01069135

Gene Name

RABGEF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000010507.1	ENSOART00000011433.1	ENSOARP00000011273.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/ZnF_A20	1.10e-18	67.0	23	57

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/ZnF_A20

   S: 1    dpskllCkkgCgfYGnpetngyCSkCyreelrrrr 35
           d+s+llCkkgCg+YGnp+++g+CSkC+ree++++r
   Q: 23   DQSELLCKKGCGYYGNPAWQGFCSKCWREEYHKAR 57
           79*******************************86 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

LVCSLISRRK MSLKSERRGI HVDQSELLCK KGCGYYGNPA WQGFCSKCWR EEYHKARQKQ 60
IQEDWELAER LQREEEEAFA SSQSSQGAQS LTFSKFEEKK TNEKTRKVTT VKKFFSASSR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTGTTTGCT CTTTGATTAG CAGGAGGAAG ATGAGCCTTA AGTCTGAACG CCGAGGAATT 60
CATGTGGATC AGTCAGAGCT GCTATGCAAG AAAGGATGTG GTTACTACGG CAACCCTGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003123--VPS9
IPR002653--Znf_A20

PROSITE

PS51205--VPS9
PS51036--ZF_A20

Pfam

PF02204--VPS9
PF01754--zf-A20

SMART

SM00167--VPS9
SM00259--ZnF_A20

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0005730--C:nucleolus
GO:0003677--F:DNA binding
GO:0017112--F:Rab guanyl-nucleotide exchange factor activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0050728--P:negative regulation of inflammatory response
GO:1900165--P:negative regulation of interleukin-6 secretion
GO:1900235--P:negative regulation of Kit signaling pathway
GO:0002686--P:negative regulation of leukocyte migration
GO:0043305--P:negative regulation of mast cell degranulation
GO:0001933--P:negative regulation of protein phosphorylation
GO:0046580--P:negative regulation of Ras protein signal transduction
GO:0048261--P:negative regulation of receptor-mediated endocytosis
GO:0006612--P:protein targeting to membrane
GO:0060368--P:regulation of Fc receptor mediated stimulatory signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000198	Aegilops tauschii	31.05	4.00e-21	96.30
IUUC-Aml-001771	Ailuropoda melanoleuca	88.00	0.00e+00	754.00
IUUC-Atr-003154	Amborella trichopoda	36.52	1.00e-23	104.00
IUUC-Apl-004018	Anas platyrhynchos	92.29	0.00e+00	853.00
IUUC-Aca-005227	Anolis carolinensis	25.26	1.00e-09	58.50
IUUC-Aly-006138	Arabidopsis lyrata	35.75	1.00e-24	107.00
IUUC-Ath-006929	Arabidopsis thaliana	32.44	3.00e-26	112.00
IUUC-Ago-007776	Ashbya gossypii	29.88	7.00e-23	101.00
IUUC-Acl-008235	Aspergillus clavatus	31.94	8.00e-28	119.00
IUUC-Afl-008570	Aspergillus flavus	31.68	2.00e-30	127.00
IUUC-Afu-008815	Aspergillus fumigatus	31.58	1.00e-28	121.00
IUUC-Ani-009381	Aspergillus nidulans	30.28	5.00e-28	119.00
IUUC-Ang-009615	Aspergillus niger	30.72	3.00e-30	126.00
IUUC-Aor-010195	Aspergillus oryzae	32.01	4.00e-31	129.00
IUUC-Ate-010514	Aspergillus terreus	32.67	1.00e-29	124.00
IUUC-Ame-011365	Astyanax mexicanus	66.27	0.00e+00	665.00
IUUC-Bgr-012102	Blumeria graminis	25.88	6.00e-29	122.00
IUUC-Bta-013124	Bos taurus	99.39	0.00e+00	896.00
IUUC-Bci-013943	Botrytis cinerea	30.74	5.00e-29	123.00
IUUC-Bdi-014539	Brachypodium distachyon	37.22	8.00e-27	114.00
IUUC-Bol-016580	Brassica oleracea	35.40	5.00e-30	125.00
IUUC-Bra-017843	Brassica rapa	34.96	9.00e-30	124.00
IUUC-Cel-018199	Caenorhabditis elegans	34.02	1.00e-57	217.00
IUUC-Cja-019941	Callithrix jacchus	96.59	0.00e+00	886.00
IUUC-Cfa-020845	Canis familiaris	97.83	0.00e+00	819.00
IUUC-Cpo-022037	Cavia porcellus	96.15	0.00e+00	868.00
IUUC-Cre-022696	Chlamydomonas reinhardtii	31.47	1.00e-21	97.80
IUUC-Csa-023495	Chlorocebus sabaeus	96.57	0.00e+00	884.00
IUUC-Cho-025076	Choloepus hoffmanni	85.19	0.00e+00	732.00
IUUC-Cin-025400	Ciona intestinalis	45.06	3.00e-116	412.00
IUUC-Csv-025941	Ciona savignyi	37.95	4.00e-84	305.00
IUUC-Cgl-026725	Colletotrichum gloeosporioides	29.58	7.00e-26	112.00
IUUC-Cne-027057	Cryptococcus neoformans	30.43	7.00e-33	135.00
IUUC-Dre-028484	Danio rerio	67.00	0.00e+00	670.00
IUUC-Dno-028906	Dasypus novemcinctus	97.57	0.00e+00	875.00
IUUC-Dor-030124	Dipodomys ordii	86.18	0.00e+00	746.00
IUUC-Dse-031437	Dothistroma septosporum	28.21	2.00e-24	108.00
IUUC-Dme-031696	Drosophila melanogaster	32.29	2.00e-67	250.00
IUUC-Ete-032573	Echinops telfairi	91.76	0.00e+00	714.00
IUUC-Eca-033711	Equus caballus	98.17	0.00e+00	890.00
IUUC-Eeu-034459	Erinaceus europaeus	73.08	9.00e-77	281.00
IUUC-Fca-035447	Felis catus	95.13	0.00e+00	895.00
IUUC-Fal-036605	Ficedula albicollis	88.93	0.00e+00	785.00
IUUC-Fox-037967	Fusarium oxysporum	26.98	2.00e-17	84.70
IUUC-Fso-038110	Fusarium solani	30.10	9.00e-28	119.00
IUUC-Gmo-038785	Gadus morhua	66.93	0.00e+00	672.00
IUUC-Ggr-039760	Gaeumannomyces graminis	30.58	7.00e-26	112.00
IUUC-Gga-040584	Gallus gallus	92.90	0.00e+00	855.00
IUUC-Gac-042469	Gasterosteus aculeatus	64.06	3.00e-166	578.00
IUUC-Gma-044237	Glycine max	37.43	6.00e-27	115.00
IUUC-Ggo-044498	Gorilla gorilla	83.57	0.00e+00	736.00
IUUC-Hsa-046625	Homo sapiens	96.59	0.00e+00	886.00
IUUC-Hvu-047155	Hordeum vulgare	36.67	5.00e-27	115.00
IUUC-Itr-048753	Ictidomys tridecemlineatus	96.35	0.00e+00	872.00
IUUC-Kpa-049160	Komagataella pastoris	29.73	2.00e-23	104.00
IUUC-Lch-050529	Latimeria chalumnae	78.92	0.00e+00	852.00
IUUC-Lpe-051024	Leersia perrieri	33.94	5.00e-29	122.00
IUUC-Loc-052644	Lepisosteus oculatus	70.26	0.00e+00	667.00
IUUC-Lma-053102	Leptosphaeria maculans	31.64	7.00e-26	112.00
IUUC-Laf-054337	Loxodonta africana	94.73	0.00e+00	862.00
IUUC-Mcc-055659	Macaca mulatta	96.44	2.00e-176	611.00
IUUC-Meu-056084	Macropus eugenii	75.57	6.00e-94	337.00
IUUC-Mor-057255	Magnaporthe oryzae	29.50	2.00e-25	110.00
IUUC-Mpo-057454	Magnaporthe poae	30.58	1.00e-27	118.00
IUUC-Mtr-058098	Medicago truncatula	35.27	5.00e-31	129.00
IUUC-Mla-059068	Melampsora laricipopulina	30.71	6.00e-30	125.00
IUUC-Mga-059624	Meleagris gallopavo	78.73	0.00e+00	840.00
IUUC-Mvi-060282	Microbotryum violaceum	28.75	7.00e-25	109.00
IUUC-Mmr-061142	Microcebus murinus	96.99	0.00e+00	894.00
IUUC-Mdo-062289	Monodelphis domestica	92.70	0.00e+00	894.00
IUUC-Mmu-063961	Mus musculus	96.15	0.00e+00	871.00
IUUC-Mac-065188	Musa acuminata	32.68	2.00e-23	103.00
IUUC-Mpu-066291	Mustela putorius furo	96.02	0.00e+00	892.00
IUUC-Mlu-067431	Myotis lucifugus	92.84	0.00e+00	862.00
IUUC-Nfi-068422	Neosartorya fischeri	31.91	1.00e-29	124.00
IUUC-Ncr-068843	Neurospora crassa	29.79	2.00e-27	117.00
IUUC-Nle-069079	Nomascus leucogenys	96.55	0.00e+00	873.00
IUUC-Opr-070790	Ochotona princeps	93.52	1.00e-56	214.00
IUUC-Ont-071789	Oreochromis niloticus	67.38	3.00e-176	611.00
IUUC-Oan-072946	Ornithorhynchus anatinus	90.49	0.00e+00	820.00
IUUC-Ocu-073816	Oryctolagus cuniculus	97.78	0.00e+00	890.00
IUUC-Oba-075738	Oryza barthii	33.15	4.00e-18	85.90
IUUC-Obr-076355	Oryza brachyantha	36.81	6.00e-28	118.00
IUUC-Ogl-077217	Oryza glaberrima	36.61	1.00e-24	107.00
IUUC-Ogu-078197	Oryza glumaepatula	27.95	4.00e-27	115.00
IUUC-Oin-080047	Oryza indica	37.64	2.00e-26	113.00
IUUC-Olo-080317	Oryza longistaminata	27.95	4.00e-27	115.00
IUUC-Ome-081589	Oryza meridionalis	36.11	1.00e-26	114.00
IUUC-Oni-082700	Oryza nivara	33.15	3.00e-18	86.30
IUUC-Opu-083923	Oryza punctata	32.07	8.00e-22	97.40
IUUC-Oru-084318	Oryza rufipogon	33.15	3.00e-18	86.30
IUUC-Osa-086246	Oryza sativa	38.98	6.00e-06	41.60
IUUC-Ola-086730	Oryzias latipes	57.14	3.00e-149	521.00
IUUC-Olu-087719	Ostreococcus lucimarinus	33.89	2.00e-23	103.00
IUUC-Oga-088992	Otolemur garnettii	85.14	0.00e+00	894.00
IUUC-Ptr-091636	Pan troglodytes	97.16	0.00e+00	877.00
IUUC-Pan-092911	Papio anubis	96.02	0.00e+00	889.00
IUUC-Psi-093194	Pelodiscus sinensis	79.38	0.00e+00	842.00
IUUC-Pma-094212	Petromyzon marinus	48.50	7.00e-113	400.00
IUUC-Pno-094831	Phaeosphaeria nodorum	29.79	7.00e-26	112.00
IUUC-Ppa-095705	Physcomitrella patens	33.86	4.00e-29	122.00
IUUC-Pfo-096694	Poecilia formosa	65.16	7.00e-178	616.00
IUUC-Pab-097706	Pongo abelii	96.78	0.00e+00	882.00
IUUC-Pop-099891	Populus trichocarpa	33.21	6.00e-27	115.00
IUUC-Pca-100879	Procavia capensis	93.49	4.00e-90	324.00
IUUC-Ppe-101334	Prunus persica	34.08	3.00e-27	116.00
IUUC-Pva-103225	Pteropus vampyrus	82.09	0.00e+00	712.00
IUUC-Pgr-103564	Puccinia graminis	30.27	7.00e-30	125.00
IUUC-Ptt-103802	Puccinia triticina	30.12	5.00e-26	112.00
IUUC-Pte-104345	Pyrenophora teres	30.55	5.00e-26	113.00
IUUC-Pyt-104716	Pyrenophora triticirepentis	30.50	6.00e-27	116.00
IUUC-Rno-106101	Rattus norvegicus	94.83	0.00e+00	877.00
IUUC-Sce-106460	Saccharomyces cerevisiae	30.00	4.00e-23	102.00
IUUC-Sha-106919	Sarcophilus harrisii	79.93	0.00e+00	850.00
IUUC-Sja-107880	Schizosaccharomyces japonicus	32.29	7.00e-29	122.00
IUUC-Spo-108087	Schizosaccharomyces pombe	29.73	8.00e-26	112.00
IUUC-Ssl-108614	Sclerotinia sclerotiorum	29.82	2.00e-07	51.20
IUUC-Smo-109411	Selaginella moellendorffii	37.14	3.00e-29	122.00
IUUC-Sit-110678	Setaria italica	36.11	7.00e-27	115.00
IUUC-Sly-111526	Solanum lycopersicum	37.85	3.00e-26	113.00
IUUC-Stu-112494	Solanum tuberosum	38.42	6.00e-27	115.00
IUUC-Sar-112929	Sorex araneus	98.19	6.00e-163	567.00
IUUC-Sbi-114242	Sorghum bicolor	32.16	9.00e-29	121.00
IUUC-Sre-115224	Sporisorium reilianum	31.67	6.00e-29	123.00
IUUC-Ssc-115239	Sus scrofa	98.17	0.00e+00	894.00
IUUC-Tgu-117499	Taeniopygia guttata	90.26	0.00e+00	823.00
IUUC-Tru-118027	Takifugu rubripes	63.71	7.00e-142	497.00
IUUC-Tsy-119462	Tarsius syrichta	97.07	0.00e+00	857.00
IUUC-Tni-120855	Tetraodon nigroviridis	60.44	3.00e-173	601.00
IUUC-Tca-121213	Theobroma cacao	33.03	8.00e-26	111.00
IUUC-Tre-122186	Trichoderma reesei	29.77	8.00e-28	118.00
IUUC-Tvi-122541	Trichoderma virens	28.37	3.00e-28	120.00
IUUC-Tae-123631	Triticum aestivum	33.46	5.00e-28	119.00
IUUC-Tur-126572	Triticum urartu	31.10	2.00e-27	117.00
IUUC-Tme-127023	Tuber melanosporum	32.80	2.00e-30	127.00
IUUC-Tbe-127453	Tupaia belangeri	96.90	0.00e+00	772.00
IUUC-Ttr-128526	Tursiops truncatus	98.17	0.00e+00	887.00
IUUC-Uma-129660	Ustilago maydis	32.82	1.00e-29	125.00
IUUC-Vda-129737	Verticillium dahliae	28.81	2.00e-23	104.00
IUUC-Vpa-130505	Vicugna pacos	91.21	0.00e+00	711.00
IUUC-Vvi-131088	Vitis vinifera	37.08	9.00e-25	107.00
IUUC-Xtr-132799	Xenopus tropicalis	74.80	0.00e+00	741.00
IUUC-Xma-133345	Xiphophorus maculatus	65.56	4.00e-173	601.00
IUUC-Yli-134416	Yarrowia lipolytica	32.85	3.00e-31	129.00
IUUC-Zma-134750	Zea mays	36.67	9.00e-27	114.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence