iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Cancer Mutation
TCGA	ICGC	COSMIC	CGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	TCGA	ICGC
COSMIC	THPA	HPM
DNA & RNA Element
UTRdb	AREsite	CircNet	miRTarBase
microRNA	TRANSFAC	TargetScan	RepTar
miRNAMap	SomamiR	miRcode	RAID2
Protein-protein Interaction
IID	Mentha
Disease-associated Information
GWASdb	OMIM
Drug and target
TTD
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
DNA Methylation
TCGA	ICGC	COSMIC
Protein Expression/Proteomics
THPA	HPM	GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/Other	E3 activity/Other	21042649

Organism

Homo sapiens

Functional Description
(View)

Homodimer; disulfide-linked.

Protein Sequence
(Fasta)

MLQNSAVLLV LVISASATHE AEQNDSVSPR KSRVAAQNSA EVVRCLNSAL QVGCGAFACL 60
ENSTCDTDGM YDICKSFLYS AAKFDTQGKA FVKESLKCIA NGVTSKVFLA IRRCSTFQRM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGTTTGCAA AAGCCAGAGG TGCAAGAAGC AGCGACTGCA GCAGCAGCAG CAGCAGCGGC 60
GGTGGCAGCA GCAGCAGCAG CGGCGGCAGC AGCAGCAGCA GCGGAGGCAC CGGTGGCAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-1015--Disulfide bond
KW-0325--Glycoprotein
KW-0372--Hormone
KW-1185--Reference proteome
KW-0964--Secreted
KW-0732--Signal

Interpro

IPR004978--Stanniocalcin

Pfam

PF03298--Stanniocalcin

Gene Ontology

GO:0016324--C:apical plasma membrane
GO:0005737--C:cytoplasm
GO:0005615--C:extracellular space
GO:0005634--C:nucleus
GO:0060348--P:bone development
GO:0006874--P:cellular calcium ion homeostasis
GO:0071320--P:cellular response to cAMP
GO:0071385--P:cellular response to glucocorticoid stimulus
GO:0071456--P:cellular response to hypoxia
GO:0035988--P:chondrocyte proliferation
GO:0046697--P:decidualization
GO:0007566--P:embryo implantation
GO:0001886--P:endothelial cell morphogenesis
GO:0003421--P:growth plate cartilage axis specification
GO:0051926--P:negative regulation of calcium ion transport
GO:0030336--P:negative regulation of cell migration
GO:0010596--P:negative regulation of endothelial cell migration
GO:1903403--P:negative regulation of renal phosphate excretion
GO:0001503--P:ossification
GO:0090280--P:positive regulation of calcium ion import
GO:0044070--P:regulation of anion transport
GO:0086004--P:regulation of cardiac muscle cell contraction
GO:0033280--P:response to vitamin D

KEGG

hsa:6781

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001570	Ailuropoda melanoleuca	98.38	2.00e-144	504.00
IUUC-Apl-003856	Anas platyrhynchos	88.98	3.00e-126	444.00
IUUC-Aca-004398	Anolis carolinensis	67.23	5.00e-72	263.00
IUUC-Ame-011748	Astyanax mexicanus	70.43	1.00e-76	279.00
IUUC-Bta-012504	Bos taurus	95.14	5.00e-139	486.00
IUUC-Cja-019777	Callithrix jacchus	93.93	7.00e-132	462.00
IUUC-Cfa-020480	Canis familiaris	98.38	1.00e-144	505.00
IUUC-Cpo-021687	Cavia porcellus	88.21	5.00e-133	466.00
IUUC-Csa-023893	Chlorocebus sabaeus	99.60	2.00e-146	511.00
IUUC-Cho-024292	Choloepus hoffmanni	91.95	2.00e-90	323.00
IUUC-Cin-025656	Ciona intestinalis	29.02	3.00e-23	102.00
IUUC-Cgl-026414	Colletotrichum gloeosporioides	38.18	2.90e-02	33.10
IUUC-Dre-027654	Danio rerio	65.84	1.00e-81	296.00
IUUC-Dno-029650	Dasypus novemcinctus	92.71	4.00e-129	453.00
IUUC-Dor-030359	Dipodomys ordii	95.65	7.00e-120	422.00
IUUC-Ete-032471	Echinops telfairi	91.21	8.00e-47	180.00
IUUC-Eca-034200	Equus caballus	96.76	5.00e-142	496.00
IUUC-Eeu-034496	Erinaceus europaeus	96.76	2.00e-142	498.00
IUUC-Fca-036162	Felis catus	97.57	5.00e-143	499.00
IUUC-Fal-037021	Ficedula albicollis	86.90	2.00e-120	424.00
IUUC-Gmo-039330	Gadus morhua	63.37	3.00e-79	288.00
IUUC-Gga-040171	Gallus gallus	88.98	6.00e-126	443.00
IUUC-Gac-041717	Gasterosteus aculeatus	65.67	1.00e-80	292.00
IUUC-Gma-044347	Glycine max	35.42	1.30e-01	30.80
IUUC-Ggo-045186	Gorilla gorilla	100.00	8.00e-147	512.00
IUUC-Hvu-047382	Hordeum vulgare	34.43	3.00e-02	32.70
IUUC-Itr-048117	Ictidomys tridecemlineatus	97.57	4.00e-136	476.00
IUUC-Lch-050223	Latimeria chalumnae	76.92	4.00e-114	404.00
IUUC-Loc-052942	Lepisosteus oculatus	70.77	4.00e-77	281.00
IUUC-Laf-053378	Loxodonta africana	97.98	1.00e-143	502.00
IUUC-Mcc-054663	Macaca mulatta	99.60	9.00e-146	509.00
IUUC-Meu-056475	Macropus eugenii	76.71	3.00e-116	410.00
IUUC-Mga-059322	Meleagris gallopavo	88.57	2.00e-112	398.00
IUUC-Mmr-061237	Microcebus murinus	98.38	9.00e-137	479.00
IUUC-Mdo-062684	Monodelphis domestica	83.74	8.00e-126	442.00
IUUC-Mmu-064414	Mus musculus	96.36	8.00e-136	476.00
IUUC-Mpu-065881	Mustela putorius furo	97.98	4.00e-144	503.00
IUUC-Mlu-067435	Myotis lucifugus	97.57	3.00e-142	497.00
IUUC-Nle-069359	Nomascus leucogenys	99.60	2.00e-146	511.00
IUUC-Opr-070546	Ochotona princeps	89.47	2.00e-132	464.00
IUUC-Ont-072479	Oreochromis niloticus	66.84	1.00e-79	289.00
IUUC-Oan-072835	Ornithorhynchus anatinus	88.26	3.00e-132	463.00
IUUC-Ocu-074860	Oryctolagus cuniculus	83.40	3.00e-123	434.00
IUUC-Olo-080649	Oryza longistaminata	25.26	1.60e-02	33.90
IUUC-Ola-086759	Oryzias latipes	58.30	1.00e-83	302.00
IUUC-Oga-089120	Otolemur garnettii	96.75	1.00e-133	468.00
IUUC-Oar-089489	Ovis aries	96.36	9.00e-140	489.00
IUUC-Ptr-091170	Pan troglodytes	100.00	8.00e-147	512.00
IUUC-Pan-092640	Papio anubis	99.60	4.00e-146	509.00
IUUC-Psi-093161	Pelodiscus sinensis	89.47	7.00e-127	446.00
IUUC-Pno-095114	Phaeosphaeria nodorum	28.77	2.70e-01	32.00
IUUC-Pfo-096888	Poecilia formosa	57.26	5.00e-81	293.00
IUUC-Pab-098660	Pongo abelii	100.00	8.00e-147	512.00
IUUC-Pop-099280	Populus trichocarpa	23.66	7.00e-02	31.60
IUUC-Pca-100490	Procavia capensis	97.50	9.00e-91	325.00
IUUC-Pva-102842	Pteropus vampyrus	96.76	3.00e-141	493.00
IUUC-Rno-105078	Rattus norvegicus	95.95	2.00e-135	474.00
IUUC-Sha-106600	Sarcophilus harrisii	83.73	2.00e-107	381.00
IUUC-Sly-111589	Solanum lycopersicum	37.50	1.30e-01	30.80
IUUC-Sar-113441	Sorex araneus	93.52	2.00e-134	471.00
IUUC-Ssc-115748	Sus scrofa	94.33	1.00e-139	488.00
IUUC-Tgu-117137	Taeniopygia guttata	86.90	3.00e-119	420.00
IUUC-Tru-118332	Takifugu rubripes	63.49	1.00e-76	279.00
IUUC-Tsy-118890	Tarsius syrichta	97.98	2.00e-143	501.00
IUUC-Tni-120180	Tetraodon nigroviridis	47.17	2.00e-56	212.00
IUUC-Tae-123845	Triticum aestivum	34.43	1.60e-02	33.90
IUUC-Tbe-127571	Tupaia belangeri	82.68	1.00e-61	229.00
IUUC-Ttr-128753	Tursiops truncatus	96.36	1.00e-140	492.00
IUUC-Vpa-130634	Vicugna pacos	95.65	1.00e-115	408.00
IUUC-Xtr-131971	Xenopus tropicalis	71.16	2.00e-95	341.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence