iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000015710.4	ENSCAFT00000024886.4	ENSCAFP00000023090.3
ENSCAFG00000015710.4	ENSCAFT00000046195.1	ENSCAFP00000037281.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	6.30e-09	36.0	4	42
ULD/UDP/UFD/UBX	3.90e-16	59.7	209	282

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 4    edkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
             +le l+eMGF+r +a +aL+ + n  +eaA+++L+++
   Q: 4    LTALESLIEMGFPRGRAEKALALTgNQGIEAAMDWLMEH 42
           5689********************************987 PP

ULD/UDP/UFD/UBX

   S: 2    tteqatlqiRlpdGkrlvrkFpssttleqiyqfve....yllvessdpFeLvspfPrrtlkpeehmstlqeagL 71
           +++q+++q+RlpdG  l+++F+++++l +++ +ve    ++ + ++dp +L+s+fPrr +++ ++++ lqe+g+
   Q: 209  EYDQCRIQVRLPDGTSLTQTFRAREQLAAVRLYVElhrgEEPGGDQDPVQLLSGFPRRAFSEADMERPLQELGM 282
           578********************************************************************996 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MAELTALESL IEMGFPRGRA EKALALTGNQ GIEAAMDWLM EHEDEPDVDE PLPTPLGRAL 60
GREPTVSEQS GPEGTGSTGG EGKPVLSEEE RQEQTKRMLE LVAQKQRERE EREEREALER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGAGC TGACGGCTCT AGAGAGTCTC ATCGAGATGG GCTTCCCCAG GGGACGCGCG 60
TAAGGGAGCC CCCGAACCCT GGCCCGCGGG GATCGCGGAC CTGTCTGGCC TTGCCCCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR015940--UBA
IPR009060--UBA-like
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom

PROSITE

PS50030--UBA
PS50033--UBX

Pfam

PF00627--UBA
PF00789--UBX

SMART

SM00165--UBA
SM00166--UBX

Gene Ontology

GO:0005829--C:cytosol
GO:0000502--C:proteasome complex
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:1904293--P:negative regulation of ERAD pathway
GO:0032435--P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:1903094--P:negative regulation of protein K48-linked deubiquitination
GO:0031397--P:negative regulation of protein ubiquitination
GO:2000157--P:negative regulation of ubiquitin-specific protease activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002325	Ailuropoda melanoleuca	96.07	4.00e-95	340.00
IUUC-Aca-004329	Anolis carolinensis	70.89	1.00e-39	155.00
IUUC-Ath-006887	Arabidopsis thaliana	49.09	6.00e-11	62.00
IUUC-Ame-011399	Astyanax mexicanus	50.51	7.00e-57	213.00
IUUC-Bta-013151	Bos taurus	91.90	1.00e-101	362.00
IUUC-Bol-016537	Brassica oleracea	49.09	6.00e-11	62.00
IUUC-Bra-017906	Brassica rapa	56.82	1.00e-10	61.60
IUUC-Cja-019084	Callithrix jacchus	87.21	4.00e-94	337.00
IUUC-Cpo-021736	Cavia porcellus	78.52	2.00e-74	271.00
IUUC-Csa-024040	Chlorocebus sabaeus	88.38	1.00e-89	322.00
IUUC-Cho-024543	Choloepus hoffmanni	91.11	4.00e-67	247.00
IUUC-Cin-025719	Ciona intestinalis	39.01	5.00e-34	137.00
IUUC-Csv-025854	Ciona savignyi	37.15	7.00e-31	127.00
IUUC-Cme-027235	Cyanidioschyzon merolae	40.32	6.00e-08	52.40
IUUC-Dre-027745	Danio rerio	48.11	6.00e-50	191.00
IUUC-Dno-029598	Dasypus novemcinctus	87.63	5.00e-89	320.00
IUUC-Dor-030917	Dipodomys ordii	72.79	4.00e-79	288.00
IUUC-Dme-032055	Drosophila melanogaster	40.88	2.00e-19	89.70
IUUC-Ete-032960	Echinops telfairi	72.94	7.00e-70	257.00
IUUC-Eca-034294	Equus caballus	92.23	3.00e-94	338.00
IUUC-Eeu-034906	Erinaceus europaeus	85.95	2.00e-98	352.00
IUUC-Fca-035653	Felis catus	95.21	6.00e-96	343.00
IUUC-Gmo-038755	Gadus morhua	48.18	1.00e-49	190.00
IUUC-Gac-042481	Gasterosteus aculeatus	50.67	1.00e-47	183.00
IUUC-Ggo-044821	Gorilla gorilla	85.57	4.00e-95	340.00
IUUC-Hsa-046797	Homo sapiens	87.68	9.00e-91	326.00
IUUC-Itr-048850	Ictidomys tridecemlineatus	88.38	1.00e-93	336.00
IUUC-Lch-049508	Latimeria chalumnae	63.64	1.00e-24	107.00
IUUC-Laf-053932	Loxodonta africana	92.25	3.00e-105	374.00
IUUC-Mcc-055300	Macaca mulatta	88.38	1.00e-89	322.00
IUUC-Mvi-060245	Microbotryum violaceum	35.53	3.00e-08	52.40
IUUC-Mmr-060979	Microcebus murinus	88.38	2.00e-91	328.00
IUUC-Mdo-062299	Monodelphis domestica	82.59	7.00e-78	283.00
IUUC-Mmu-063212	Mus musculus	90.85	2.00e-98	351.00
IUUC-Mpu-066540	Mustela putorius furo	94.70	5.00e-95	340.00
IUUC-Mlu-067589	Myotis lucifugus	92.93	1.00e-100	359.00
IUUC-Nle-069045	Nomascus leucogenys	89.72	1.00e-72	265.00
IUUC-Opr-070772	Ochotona princeps	86.67	8.00e-90	323.00
IUUC-Ont-072006	Oreochromis niloticus	50.99	5.00e-49	187.00
IUUC-Oan-073244	Ornithorhynchus anatinus	61.01	3.00e-43	168.00
IUUC-Ocu-074333	Oryctolagus cuniculus	86.97	6.00e-92	330.00
IUUC-Oni-082110	Oryza nivara	50.00	2.00e-09	56.60
IUUC-Ola-086781	Oryzias latipes	48.67	2.00e-45	175.00
IUUC-Oga-088429	Otolemur garnettii	90.85	1.00e-91	329.00
IUUC-Oar-089885	Ovis aries	91.20	6.00e-101	360.00
IUUC-Ptr-091315	Pan troglodytes	85.25	6.00e-95	340.00
IUUC-Pan-092885	Papio anubis	88.38	1.00e-89	322.00
IUUC-Psi-093299	Pelodiscus sinensis	69.01	1.00e-54	206.00
IUUC-Pma-094221	Petromyzon marinus	61.04	2.00e-23	100.00
IUUC-Ppa-095484	Physcomitrella patens	48.89	1.00e-09	57.80
IUUC-Pfo-096188	Poecilia formosa	51.34	4.00e-47	181.00
IUUC-Pab-097881	Pongo abelii	82.39	2.00e-88	318.00
IUUC-Pca-100977	Procavia capensis	89.42	3.00e-97	347.00
IUUC-Ppe-101243	Prunus persica	45.10	4.00e-09	55.50
IUUC-Pva-102169	Pteropus vampyrus	85.86	1.00e-94	339.00
IUUC-Rno-105459	Rattus norvegicus	90.85	1.00e-98	352.00
IUUC-Sha-107526	Sarcophilus harrisii	84.45	2.00e-78	285.00
IUUC-Sit-110434	Setaria italica	50.00	1.00e-08	53.90
IUUC-Sar-112945	Sorex araneus	90.68	6.00e-62	230.00
IUUC-Sbi-114159	Sorghum bicolor	50.00	4.00e-09	55.50
IUUC-Ssc-116114	Sus scrofa	88.03	4.00e-82	297.00
IUUC-Tru-117839	Takifugu rubripes	50.00	1.00e-48	186.00
IUUC-Tsy-118813	Tarsius syrichta	68.85	6.00e-87	313.00
IUUC-Tni-120504	Tetraodon nigroviridis	53.29	6.00e-48	184.00
IUUC-Tbe-128034	Tupaia belangeri	85.57	2.00e-95	342.00
IUUC-Ttr-128468	Tursiops truncatus	84.69	2.00e-99	355.00
IUUC-Vpa-130179	Vicugna pacos	87.45	7.00e-62	229.00
IUUC-Xtr-132119	Xenopus tropicalis	60.42	5.00e-56	211.00
IUUC-Xma-134067	Xiphophorus maculatus	51.18	1.00e-46	179.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence