iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-067589

Ensembl Protein ID

ENSMLUP00000000371.2

UniProt Accession

G1NT85; G1NT85_MYOLU

Genbank Protein ID

ENSMLUP00000000371

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02052749

Gene Name

UBXN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000000406.2	ENSMLUT00000000407.2	ENSMLUP00000000371.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	5.00e-09	36.1	4	42
ULD/UDP/UFD/UBX	1.80e-20	73.3	209	290

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 4    edkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
             +le l+eMGF+r +a +aL+ + n  +eaA+++L+++
   Q: 4    LTALESLIEMGFPRGRAEKALALTgNQGIEAAMDWLMEH 42
           5689********************************987 PP

ULD/UDP/UFD/UBX

   S: 2    tteqatlqiRlpdGkrlvrkFpssttleqiyqfve....yllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsllv 79
           +++q+++q+RlpdG  l+++F+++++l +++ +ve    ++ + ++dp +L+s+fPrr +++ ++++ lqe+gLvps++l+v
   Q: 209  EYDQCRIQVRLPDGTSLTQTFRAREQLAAVRLYVElhrgEEPGGDQDPVQLLSGFPRRAFSEADMERPLQELGLVPSAVLIV 290
           578*****************************************************************************98 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MAELTALESL IEMGFPRGRA EKALALTGNQ GIEAAMDWLM EHEDDPDVDE PLPTPLGHVL 60
GREPTSSEQG GPEGPGSPAE EGKLVLSEEE RQEQTKRMLE LVAQKQRERE EREEREALER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGAGC TGACGGCTCT GGAGAGTCTC ATCGAGATGG GCTTCCCCAG GGGACGCGCG 60
TAAGGGAGCC CCTCTAGCCC CGGCCGCGGG GCTCGCGGGC GTGTCCGCCT TCCCCCCGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR015940--UBA
IPR009060--UBA-like
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom

PROSITE

PS50030--UBA
PS50033--UBX

Pfam

PF00627--UBA
PF00789--UBX

SMART

SM00165--UBA
SM00166--UBX

Gene Ontology

GO:0005829--C:cytosol
GO:0000502--C:proteasome complex
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:1904293--P:negative regulation of ERAD pathway
GO:0032435--P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:1903094--P:negative regulation of protein K48-linked deubiquitination
GO:0031397--P:negative regulation of protein ubiquitination
GO:2000157--P:negative regulation of ubiquitin-specific protease activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001103	Aegilops tauschii	42.11	1.00e-09	57.80
IUUC-Aml-002325	Ailuropoda melanoleuca	95.56	2.00e-110	391.00
IUUC-Atr-002867	Amborella trichopoda	33.33	4.00e-09	56.20
IUUC-Aca-004329	Anolis carolinensis	69.23	3.00e-45	174.00
IUUC-Aly-005639	Arabidopsis lyrata	43.59	7.00e-12	65.10
IUUC-Ath-006887	Arabidopsis thaliana	44.87	3.00e-12	66.20
IUUC-Ago-007989	Ashbya gossypii	35.90	6.00e-06	44.70
IUUC-Ame-011399	Astyanax mexicanus	52.90	3.00e-62	231.00
IUUC-Bta-013151	Bos taurus	92.91	2.00e-114	404.00
IUUC-Bdi-014311	Brachypodium distachyon	54.55	1.00e-09	57.40
IUUC-Bol-016537	Brassica oleracea	50.91	2.00e-11	63.50
IUUC-Bra-017906	Brassica rapa	59.09	3.00e-11	63.50
IUUC-Cel-018300	Caenorhabditis elegans	33.83	4.00e-13	68.60
IUUC-Cja-019084	Callithrix jacchus	91.90	6.00e-100	357.00
IUUC-Cfa-020997	Canis familiaris	92.93	1.00e-93	336.00
IUUC-Cpo-021736	Cavia porcellus	78.11	4.00e-81	294.00
IUUC-Csa-024040	Chlorocebus sabaeus	90.91	2.00e-99	355.00
IUUC-Cho-024543	Choloepus hoffmanni	93.56	5.00e-60	223.00
IUUC-Cin-025719	Ciona intestinalis	40.34	6.00e-36	144.00
IUUC-Csv-025854	Ciona savignyi	38.46	5.00e-35	141.00
IUUC-Cme-027235	Cyanidioschyzon merolae	43.86	4.00e-08	52.80
IUUC-Dre-027745	Danio rerio	52.16	2.00e-56	211.00
IUUC-Dno-029598	Dasypus novemcinctus	91.55	5.00e-99	353.00
IUUC-Dor-030917	Dipodomys ordii	75.35	6.00e-83	300.00
IUUC-Dme-032055	Drosophila melanogaster	41.10	6.00e-22	97.80
IUUC-Ete-032960	Echinops telfairi	76.51	2.00e-69	256.00
IUUC-Eca-034294	Equus caballus	93.58	1.00e-102	365.00
IUUC-Eeu-034906	Erinaceus europaeus	89.47	5.00e-95	340.00
IUUC-Fca-035653	Felis catus	94.35	7.00e-94	337.00
IUUC-Gmo-038755	Gadus morhua	50.32	1.00e-53	202.00
IUUC-Gac-042481	Gasterosteus aculeatus	54.52	2.00e-57	215.00
IUUC-Ggo-044821	Gorilla gorilla	89.79	5.00e-93	333.00
IUUC-Hsa-046797	Homo sapiens	90.24	4.00e-101	360.00
IUUC-Itr-048850	Ictidomys tridecemlineatus	89.90	1.00e-107	382.00
IUUC-Lch-049508	Latimeria chalumnae	67.82	3.00e-30	125.00
IUUC-Laf-053932	Loxodonta africana	93.94	5.00e-120	423.00
IUUC-Mcc-055300	Macaca mulatta	91.25	1.00e-99	355.00
IUUC-Mla-059083	Melampsora laricipopulina	28.07	9.00e-09	54.30
IUUC-Mvi-060245	Microbotryum violaceum	40.48	4.00e-12	65.10
IUUC-Mmr-060979	Microcebus murinus	90.57	8.00e-107	379.00
IUUC-Mdo-062299	Monodelphis domestica	84.81	8.00e-86	310.00
IUUC-Mmu-063212	Mus musculus	91.58	5.00e-106	377.00
IUUC-Mac-065072	Musa acuminata	60.53	1.00e-10	60.50
IUUC-Mpu-066540	Mustela putorius furo	94.59	2.00e-110	391.00
IUUC-Nle-069045	Nomascus leucogenys	90.12	1.00e-73	268.00
IUUC-Opr-070772	Ochotona princeps	90.11	7.00e-90	323.00
IUUC-Ont-072006	Oreochromis niloticus	52.87	3.00e-58	218.00
IUUC-Oan-073244	Ornithorhynchus anatinus	62.23	1.00e-45	176.00
IUUC-Ocu-074333	Oryctolagus cuniculus	89.56	9.00e-104	369.00
IUUC-Oba-075451	Oryza barthii	49.06	6.00e-11	62.00
IUUC-Obr-076923	Oryza brachyantha	55.10	2.00e-11	63.90
IUUC-Ogl-077259	Oryza glaberrima	39.73	9.00e-10	58.20
IUUC-Ome-081253	Oryza meridionalis	49.06	5.00e-11	62.00
IUUC-Oni-082110	Oryza nivara	39.73	3.00e-10	59.30
IUUC-Oru-085235	Oryza rufipogon	49.06	6.00e-11	62.00
IUUC-Osa-085611	Oryza sativa	49.06	6.00e-11	62.00
IUUC-Ola-086781	Oryzias latipes	54.05	3.00e-56	211.00
IUUC-Oga-088429	Otolemur garnettii	90.24	1.00e-101	362.00
IUUC-Oar-089885	Ovis aries	92.23	9.00e-114	402.00
IUUC-Ptr-091315	Pan troglodytes	89.75	1.00e-92	332.00
IUUC-Pan-092885	Papio anubis	90.91	2.00e-99	355.00
IUUC-Psi-093299	Pelodiscus sinensis	70.08	1.00e-57	216.00
IUUC-Pma-094221	Petromyzon marinus	64.37	2.00e-28	117.00
IUUC-Ppa-095484	Physcomitrella patens	51.11	2.00e-10	60.10
IUUC-Pfo-096188	Poecilia formosa	53.59	7.00e-56	210.00
IUUC-Pab-097881	Pongo abelii	84.18	2.00e-98	351.00
IUUC-Pop-098863	Populus trichocarpa	59.09	1.00e-11	64.30
IUUC-Pca-100977	Procavia capensis	90.24	3.00e-94	337.00
IUUC-Ppe-101243	Prunus persica	47.06	8.00e-10	57.80
IUUC-Pva-102169	Pteropus vampyrus	89.44	7.00e-94	337.00
IUUC-Rno-105459	Rattus norvegicus	90.91	4.00e-106	377.00
IUUC-Sha-107526	Sarcophilus harrisii	85.81	7.00e-85	306.00
IUUC-Ssl-108389	Sclerotinia sclerotiorum	29.20	2.00e-05	43.90
IUUC-Sit-110434	Setaria italica	52.63	3.00e-09	55.50
IUUC-Sar-112945	Sorex araneus	92.21	3.00e-61	228.00
IUUC-Sbi-114159	Sorghum bicolor	52.63	1.00e-09	57.00
IUUC-Ssc-116114	Sus scrofa	89.56	3.00e-94	338.00
IUUC-Tru-117839	Takifugu rubripes	53.21	1.00e-54	206.00
IUUC-Tsy-118813	Tarsius syrichta	91.06	5.00e-51	194.00
IUUC-Tni-120504	Tetraodon nigroviridis	56.38	7.00e-56	210.00
IUUC-Tur-126615	Triticum urartu	42.11	1.00e-09	57.80
IUUC-Tbe-128034	Tupaia belangeri	88.73	3.00e-98	351.00
IUUC-Ttr-128468	Tursiops truncatus	83.78	2.00e-97	348.00
IUUC-Uma-129569	Ustilago maydis	33.33	1.00e-04	40.40
IUUC-Vpa-130179	Vicugna pacos	87.45	5.00e-67	246.00
IUUC-Xtr-132119	Xenopus tropicalis	62.08	6.00e-65	240.00
IUUC-Xma-134067	Xiphophorus maculatus	52.77	5.00e-56	211.00
IUUC-Zma-134709	Zea mays	54.05	2.00e-09	56.60

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence