iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-074333

Ensembl Protein ID

ENSOCUP00000014846.2

UniProt Accession

G1TDD2; G1TDD2_RABIT

Protein Name

Uncharacterized protein

Gene Name

UBXN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000017278.2	ENSOCUT00000017279.2	ENSOCUP00000014846.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	4.90e-09	36.1	4	42
ULD/UDP/UFD/UBX	3.90e-20	72.2	210	291

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 4    edkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
             +le l+eMGF+r +a +aL+ + n  +eaA+++L+++
   Q: 4    LTALESLIEMGFPRGRAEKALALTgNQGIEAAMDWLMEH 42
           5689********************************987 PP

ULD/UDP/UFD/UBX

   S: 2    tteqatlqiRlpdGkrlvrkFpssttleqiyqfve....yllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsllv 79
           +++q+++q+RlpdG  l+++F+++++l +++ +ve    ++ +  +dp +L+s+fPrr +++ ++++ lqe+gLvps++l+v
   Q: 210  EYDQCRIQVRLPDGTSLTQTFRAREQLAAVRLYVElhrgEEPGGGQDPVQLLSGFPRRAFSEADMERPLQELGLVPSAVLIV 291
           578*****************************************************************************98 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MAELTALESL IEMGFPRGRA EKALALTGNQ GIEAAMDWLM EHEDDPDVDE PLQAPLGHVL 60
GREPTSLEQS GAAGPGSAAG EGKPALSEEE RQEQTKRMME LVAQKQRERE EREEREALER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGAGC TGACGGCTCT GGAGAGCCTC ATCGAGATGG GCTTCCCCAG GGGACGCGCG 60
TAAGGGAGCC TCCTCGCCCC GATCCGCGCG GACCGGTCCC GGCCTTTCCC CGAGCCTGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR015940--UBA
IPR009060--UBA-like
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom

PROSITE

PS50030--UBA
PS50033--UBX

Pfam

PF00627--UBA
PF00789--UBX

SMART

SM00165--UBA
SM00166--UBX

Gene Ontology

GO:0005829--C:cytosol
GO:0000502--C:proteasome complex
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:1904293--P:negative regulation of ERAD pathway
GO:0032435--P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:1903094--P:negative regulation of protein K48-linked deubiquitination
GO:0031397--P:negative regulation of protein ubiquitination
GO:2000157--P:negative regulation of ubiquitin-specific protease activity

KEGG

ocu:100348858

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001103	Aegilops tauschii	36.25	2.00e-09	56.60
IUUC-Aml-002325	Ailuropoda melanoleuca	92.86	2.00e-102	365.00
IUUC-Atr-002907	Amborella trichopoda	42.37	1.00e-09	57.40
IUUC-Aca-004329	Anolis carolinensis	64.88	8.00e-44	169.00
IUUC-Aly-005639	Arabidopsis lyrata	50.91	5.00e-12	65.50
IUUC-Ath-006887	Arabidopsis thaliana	50.91	7.00e-12	65.10
IUUC-Ago-007989	Ashbya gossypii	37.18	9.00e-07	47.40
IUUC-Ame-011399	Astyanax mexicanus	52.77	2.00e-58	219.00
IUUC-Bta-013151	Bos taurus	92.91	2.00e-111	394.00
IUUC-Bdi-014311	Brachypodium distachyon	54.55	1.00e-09	57.80
IUUC-Bol-016537	Brassica oleracea	50.91	8.00e-12	64.70
IUUC-Bra-017906	Brassica rapa	59.09	3.00e-11	63.90
IUUC-Cel-018300	Caenorhabditis elegans	34.85	7.00e-13	67.80
IUUC-Cja-019084	Callithrix jacchus	94.72	2.00e-95	342.00
IUUC-Cfa-020997	Canis familiaris	90.85	4.00e-89	320.00
IUUC-Cpo-021736	Cavia porcellus	79.12	2.00e-83	301.00
IUUC-Csa-024040	Chlorocebus sabaeus	95.29	8.00e-102	363.00
IUUC-Cho-024543	Choloepus hoffmanni	95.05	1.00e-64	238.00
IUUC-Cin-025719	Ciona intestinalis	39.12	8.00e-36	144.00
IUUC-Csv-025854	Ciona savignyi	45.45	6.00e-19	87.80
IUUC-Cme-027235	Cyanidioschyzon merolae	47.73	4.00e-08	52.80
IUUC-Dre-027745	Danio rerio	47.17	7.00e-55	207.00
IUUC-Dno-029598	Dasypus novemcinctus	91.92	2.00e-100	358.00
IUUC-Dor-030917	Dipodomys ordii	81.34	7.00e-80	290.00
IUUC-Dme-032055	Drosophila melanogaster	42.33	2.00e-23	102.00
IUUC-Ete-032960	Echinops telfairi	77.30	7.00e-69	253.00
IUUC-Eca-034294	Equus caballus	94.61	2.00e-107	382.00
IUUC-Eeu-034906	Erinaceus europaeus	89.47	1.00e-97	349.00
IUUC-Fca-035653	Felis catus	91.20	6.00e-91	327.00
IUUC-Gmo-038755	Gadus morhua	48.11	2.00e-51	195.00
IUUC-Gac-042481	Gasterosteus aculeatus	53.55	1.00e-54	206.00
IUUC-Gma-042684	Glycine max	52.00	2.00e-10	60.10
IUUC-Ggo-044821	Gorilla gorilla	94.01	5.00e-95	340.00
IUUC-Hsa-046797	Homo sapiens	94.95	3.00e-104	371.00
IUUC-Hvu-047779	Hordeum vulgare	55.26	5.00e-09	55.10
IUUC-Itr-048850	Ictidomys tridecemlineatus	93.94	2.00e-104	371.00
IUUC-Lch-049508	Latimeria chalumnae	51.23	2.00e-50	192.00
IUUC-Lpe-051322	Leersia perrieri	51.02	4.00e-10	58.90
IUUC-Laf-053932	Loxodonta africana	95.29	2.00e-118	417.00
IUUC-Mcc-055300	Macaca mulatta	95.62	6.00e-102	363.00
IUUC-Mtr-058774	Medicago truncatula	50.00	7.00e-10	57.80
IUUC-Mvi-060245	Microbotryum violaceum	40.48	3.00e-12	65.50
IUUC-Mmr-060979	Microcebus murinus	88.22	2.00e-100	358.00
IUUC-Mdo-062299	Monodelphis domestica	85.56	1.00e-89	322.00
IUUC-Mmu-063212	Mus musculus	91.58	7.00e-107	379.00
IUUC-Mac-065072	Musa acuminata	59.09	9.00e-11	60.80
IUUC-Mpu-066540	Mustela putorius furo	93.94	2.00e-104	371.00
IUUC-Mlu-067589	Myotis lucifugus	93.60	4.00e-107	380.00
IUUC-Nle-069045	Nomascus leucogenys	92.49	4.00e-74	270.00
IUUC-Opr-070772	Ochotona princeps	86.91	2.00e-90	325.00
IUUC-Ont-072006	Oreochromis niloticus	53.82	2.00e-55	208.00
IUUC-Oan-073244	Ornithorhynchus anatinus	87.34	1.00e-35	143.00
IUUC-Oba-075451	Oryza barthii	49.06	5.00e-11	62.00
IUUC-Obr-076923	Oryza brachyantha	55.10	1.00e-11	64.30
IUUC-Ogl-077259	Oryza glaberrima	52.27	1.00e-09	57.80
IUUC-Ogu-078589	Oryza glumaepatula	49.06	5.00e-11	62.00
IUUC-Oin-079151	Oryza indica	49.06	5.00e-11	62.00
IUUC-Olo-080934	Oryza longistaminata	54.35	2.00e-10	60.10
IUUC-Ome-081253	Oryza meridionalis	49.06	5.00e-11	62.40
IUUC-Oni-082110	Oryza nivara	52.27	4.00e-10	58.50
IUUC-Opu-083336	Oryza punctata	45.90	4.00e-11	62.40
IUUC-Oru-085235	Oryza rufipogon	49.06	5.00e-11	62.00
IUUC-Osa-085611	Oryza sativa	49.06	5.00e-11	62.00
IUUC-Ola-086781	Oryzias latipes	53.07	5.00e-52	197.00
IUUC-Olu-087606	Ostreococcus lucimarinus	48.94	2.00e-06	46.60
IUUC-Oga-088429	Otolemur garnettii	93.94	4.00e-103	367.00
IUUC-Oar-089885	Ovis aries	92.57	2.00e-111	395.00
IUUC-Ptr-091315	Pan troglodytes	93.66	7.00e-95	340.00
IUUC-Pan-092885	Papio anubis	95.29	8.00e-102	363.00
IUUC-Psi-093299	Pelodiscus sinensis	66.80	3.00e-56	211.00
IUUC-Pma-094221	Petromyzon marinus	64.37	2.00e-28	117.00
IUUC-Ppa-095484	Physcomitrella patens	51.11	2.00e-10	60.10
IUUC-Pfo-096188	Poecilia formosa	53.27	5.00e-53	201.00
IUUC-Pab-097881	Pongo abelii	88.22	1.00e-100	359.00
IUUC-Pop-098863	Populus trichocarpa	52.94	7.00e-12	65.10
IUUC-Pca-100977	Procavia capensis	91.99	5.00e-98	350.00
IUUC-Ppe-101243	Prunus persica	47.06	6.00e-10	58.20
IUUC-Pva-102169	Pteropus vampyrus	94.01	4.00e-95	341.00
IUUC-Rno-105459	Rattus norvegicus	90.57	9.00e-107	379.00
IUUC-Sha-107526	Sarcophilus harrisii	87.21	1.00e-89	322.00
IUUC-Ssl-108389	Sclerotinia sclerotiorum	31.71	3.00e-05	43.10
IUUC-Sit-110434	Setaria italica	52.27	3.00e-09	55.80
IUUC-Sly-111766	Solanum lycopersicum	44.83	6.00e-10	58.50
IUUC-Stu-112122	Solanum tuberosum	44.83	6.00e-10	58.50
IUUC-Sar-112945	Sorex araneus	88.26	8.00e-65	239.00
IUUC-Sbi-114159	Sorghum bicolor	52.27	1.00e-09	57.40
IUUC-Ssc-116114	Sus scrofa	94.61	9.00e-97	346.00
IUUC-Tru-117839	Takifugu rubripes	53.23	3.00e-53	201.00
IUUC-Tsy-118813	Tarsius syrichta	93.50	2.00e-54	205.00
IUUC-Tni-120504	Tetraodon nigroviridis	53.62	6.00e-52	197.00
IUUC-Tca-121495	Theobroma cacao	45.00	1.00e-10	60.80
IUUC-Tae-124974	Triticum aestivum	36.25	3.00e-09	56.20
IUUC-Tur-126615	Triticum urartu	36.05	3.00e-09	56.20
IUUC-Tbe-128034	Tupaia belangeri	93.31	2.00e-94	338.00
IUUC-Ttr-128468	Tursiops truncatus	87.16	9.00e-96	343.00
IUUC-Uma-129569	Ustilago maydis	34.62	1.00e-05	43.50
IUUC-Vpa-130179	Vicugna pacos	87.45	1.00e-66	245.00
IUUC-Vvi-131064	Vitis vinifera	54.55	3.00e-10	59.30
IUUC-Xtr-132119	Xenopus tropicalis	62.42	4.00e-63	234.00
IUUC-Xma-134067	Xiphophorus maculatus	52.12	2.00e-52	199.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence