iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-072837

UUCD1 version

UUC-OrA-00086

Ensembl Protein ID

ENSOANP00000004886.2

UniProt Accession

F6YNG5; F6YNG5_ORNAN

Protein Name

Uncharacterized protein

Gene Name

RNF149

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000003086.2	ENSOANT00000004887.2	ENSOANP00000004886.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.40e-07	32.2	262	303

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+C e +  kd +++lpC+H+fh++C+  w         + +CP C+
   Q: 262  CAVCIENYkpKDVVRILPCKHIFHRTCIDPW------LLDHRTCPMCK 303
           ******9988888******************......9999******6 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MARVGALAVL ALALCAPGGR GRAPEWYSAL VSTEYTDPRT NRTVRSGGGE GSGQGGRYGD 60
SSPKEGLRGL VGIPRSPARR MEGCARDTHY YVPPLGGAAE PWIALVARGG CTFKDKVLNA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCCCGCCCC GTTCCGCCCC CTGGCGGTGG TGGGTGGTGC CGCTGCGCCG GCGGCCGCCA 60
TCGGGCGGGC TGGTCGACCG CCGGTCCTGC CGGTCCTGCC GGTCCTGCCC ATGGCGCGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003137--PA_domain
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF02225--PA
PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0035690--P:cellular response to drug
GO:0043409--P:negative regulation of MAPK cascade
GO:0031647--P:regulation of protein stability

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001968	Ailuropoda melanoleuca	68.09	1.00e-145	508.00
IUUC-Apl-004109	Anas platyrhynchos	78.20	4.00e-113	400.00
IUUC-Ago-007863	Ashbya gossypii	38.10	2.00e-07	50.10
IUUC-Bta-012340	Bos taurus	70.03	2.00e-144	504.00
IUUC-Cja-019566	Callithrix jacchus	67.72	9.00e-140	489.00
IUUC-Cfa-020289	Canis familiaris	74.06	9.00e-98	348.00
IUUC-Cpo-021916	Cavia porcellus	56.03	1.00e-64	238.00
IUUC-Csa-024084	Chlorocebus sabaeus	68.92	4.00e-137	480.00
IUUC-Cho-024305	Choloepus hoffmanni	71.29	5.00e-118	416.00
IUUC-Cin-025124	Ciona intestinalis	37.46	3.00e-52	197.00
IUUC-Csv-026229	Ciona savignyi	37.07	7.00e-56	210.00
IUUC-Cne-026985	Cryptococcus neoformans	31.43	5.00e-13	69.70
IUUC-Dre-027477	Danio rerio	50.34	3.00e-71	261.00
IUUC-Dno-030098	Dasypus novemcinctus	70.67	3.00e-153	533.00
IUUC-Dor-030620	Dipodomys ordii	64.92	6.00e-119	419.00
IUUC-Dme-032142	Drosophila melanogaster	43.51	2.00e-51	196.00
IUUC-Ete-032306	Echinops telfairi	75.00	4.00e-155	540.00
IUUC-Fca-035950	Felis catus	71.95	1.00e-104	371.00
IUUC-Fal-037429	Ficedula albicollis	71.28	6.00e-149	519.00
IUUC-Fso-038141	Fusarium solani	40.00	1.00e-13	70.10
IUUC-Gmo-038987	Gadus morhua	46.98	1.00e-59	223.00
IUUC-Gga-041201	Gallus gallus	70.18	5.00e-143	499.00
IUUC-Ggo-045429	Gorilla gorilla	69.04	3.00e-135	473.00
IUUC-Hsa-046191	Homo sapiens	69.31	1.00e-138	485.00
IUUC-Itr-048018	Ictidomys tridecemlineatus	67.29	5.00e-126	443.00
IUUC-Lch-049498	Latimeria chalumnae	65.32	1.00e-141	495.00
IUUC-Laf-054239	Loxodonta africana	64.79	5.00e-118	416.00
IUUC-Meu-056382	Macropus eugenii	76.03	3.00e-162	563.00
IUUC-Mla-058935	Melampsora laricipopulina	43.75	2.00e-08	53.90
IUUC-Mga-059435	Meleagris gallopavo	72.87	6.00e-71	259.00
IUUC-Mmr-061513	Microcebus murinus	69.94	7.00e-137	479.00
IUUC-Mdo-063028	Monodelphis domestica	76.39	1.00e-170	591.00
IUUC-Mmu-063545	Mus musculus	67.74	4.00e-128	450.00
IUUC-Mpu-066370	Mustela putorius furo	68.98	8.00e-144	502.00
IUUC-Mlu-067271	Myotis lucifugus	68.09	6.00e-121	426.00
IUUC-Nle-069207	Nomascus leucogenys	69.84	9.00e-142	495.00
IUUC-Opr-070704	Ochotona princeps	63.97	3.00e-87	313.00
IUUC-Ont-072549	Oreochromis niloticus	49.66	5.00e-71	260.00
IUUC-Ocu-074671	Oryctolagus cuniculus	69.58	8.00e-106	375.00
IUUC-Oga-089083	Otolemur garnettii	66.84	8.00e-140	489.00
IUUC-Oar-089254	Ovis aries	69.92	9.00e-99	352.00
IUUC-Ptr-090940	Pan troglodytes	69.87	3.00e-140	490.00
IUUC-Pan-092636	Papio anubis	68.11	7.00e-136	476.00
IUUC-Psi-093435	Pelodiscus sinensis	77.73	4.00e-105	373.00
IUUC-Pfo-096155	Poecilia formosa	51.03	5.00e-72	264.00
IUUC-Pab-098525	Pongo abelii	69.45	1.00e-140	492.00
IUUC-Pva-102395	Pteropus vampyrus	68.65	8.00e-149	519.00
IUUC-Pgr-103263	Puccinia graminis	36.67	4.00e-10	59.70
IUUC-Ptt-103733	Puccinia triticina	45.10	6.00e-10	57.40
IUUC-Rno-105789	Rattus norvegicus	69.21	2.00e-127	448.00
IUUC-Sce-106136	Saccharomyces cerevisiae	41.18	1.00e-06	47.40
IUUC-Sha-107305	Sarcophilus harrisii	76.37	1.00e-108	384.00
IUUC-Ssc-115598	Sus scrofa	69.95	8.00e-140	489.00
IUUC-Tgu-116463	Taeniopygia guttata	74.71	2.00e-144	504.00
IUUC-Tru-117952	Takifugu rubripes	50.00	7.00e-69	253.00
IUUC-Tsy-118915	Tarsius syrichta	71.14	8.00e-91	325.00
IUUC-Tni-119659	Tetraodon nigroviridis	48.97	6.00e-64	237.00
IUUC-Tre-121978	Trichoderma reesei	50.00	2.00e-12	67.00
IUUC-Tme-126970	Tuber melanosporum	45.28	1.00e-12	67.80
IUUC-Tbe-127906	Tupaia belangeri	71.59	2.00e-72	264.00
IUUC-Xtr-131821	Xenopus tropicalis	68.00	2.00e-137	481.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence