iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003504

Ensembl Protein ID

ENSAPLP00000003806.1

UniProt Accession

U3I985; U3I985_ANAPL

Genbank Protein ID

ENSAPLP00000003806

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01022615

Gene Name

IFT122

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000004234.1	ENSAPLT00000004413.1	ENSAPLP00000003806.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.70e-15	55.6	46	75

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvW 28
           gH+d v+c+a+  d ++++sGs D+++ +W
   Q: 46   GHKDTVYCVAYaKDgKRFASGSADKSVIIW 75
           8***********777*************** PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

PRAVCLSRSI YDLAFKPDGT QLIIAAGNRL LVYDTSDGTL IQPLKGHKDT VYCVAYAKDG 60
KRFASGSADK SVIIWTSKLE GILKYTHNDS IQCVSYNPLT HQLASCSSSD FGLWSPEQKS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCCGCGCTG TTTGTCTCTC CCGCAGCATT TATGACCTGG CCTTCAAGCC CGACGGCACT 60
CAGCTGATAA TCGCTGCTGG GAACAGGCTC CTGGTAGGGC AGCGGCTGCG GCCCCGTTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0036064--C:ciliary basal body
GO:0097546--C:ciliary base
GO:0005829--C:cytosol
GO:0030991--C:intraciliary transport particle A
GO:0016020--C:membrane
GO:0005654--C:nucleoplasm
GO:0032391--C:photoreceptor connecting cilium
GO:0048593--P:camera-type eye morphogenesis
GO:0060830--P:ciliary receptor clustering involved in smoothened signaling pathway
GO:0010172--P:embryonic body morphogenesis
GO:0042733--P:embryonic digit morphogenesis
GO:0035115--P:embryonic forelimb morphogenesis
GO:0060971--P:embryonic heart tube left/right pattern formation
GO:0072594--P:establishment of protein localization to organelle
GO:0035720--P:intraciliary anterograde transport
GO:0035721--P:intraciliary retrograde transport
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:0021914--P:negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
GO:0001843--P:neural tube closure
GO:1905515--P:non-motile cilium assembly
GO:0061512--P:protein localization to cilium
GO:0007227--P:signal transduction downstream of smoothened
GO:0060831--P:smoothened signaling pathway involved in dorsal/ventral neural tube patterning

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001933	Ailuropoda melanoleuca	85.67	0.00e+00	2118.00
IUUC-Aca-004767	Anolis carolinensis	85.31	0.00e+00	2151.00
IUUC-Ame-011642	Astyanax mexicanus	66.85	0.00e+00	1658.00
IUUC-Bta-012969	Bos taurus	88.58	0.00e+00	1798.00
IUUC-Cel-018670	Caenorhabditis elegans	38.96	0.00e+00	896.00
IUUC-Cja-019249	Callithrix jacchus	80.90	0.00e+00	1621.00
IUUC-Cfa-020915	Canis familiaris	85.02	0.00e+00	2071.00
IUUC-Cpo-021888	Cavia porcellus	86.25	0.00e+00	2124.00
IUUC-Cre-022789	Chlamydomonas reinhardtii	52.05	0.00e+00	1186.00
IUUC-Csa-023533	Chlorocebus sabaeus	85.61	0.00e+00	1722.00
IUUC-Cin-025121	Ciona intestinalis	61.88	0.00e+00	1558.00
IUUC-Csv-026240	Ciona savignyi	60.15	0.00e+00	1468.00
IUUC-Dno-029685	Dasypus novemcinctus	90.33	0.00e+00	2134.00
IUUC-Ete-032682	Echinops telfairi	79.42	0.00e+00	1584.00
IUUC-Eca-033831	Equus caballus	85.41	0.00e+00	2124.00
IUUC-Eeu-034919	Erinaceus europaeus	80.31	0.00e+00	947.00
IUUC-Fca-036559	Felis catus	76.29	0.00e+00	1846.00
IUUC-Fal-037340	Ficedula albicollis	91.97	0.00e+00	2209.00
IUUC-Gga-040595	Gallus gallus	96.33	0.00e+00	2335.00
IUUC-Ggo-045356	Gorilla gorilla	85.41	0.00e+00	1716.00
IUUC-Hsa-046135	Homo sapiens	85.41	0.00e+00	1715.00
IUUC-Itr-048228	Ictidomys tridecemlineatus	74.16	0.00e+00	1790.00
IUUC-Lch-050183	Latimeria chalumnae	84.38	0.00e+00	1217.00
IUUC-Loc-052049	Lepisosteus oculatus	86.02	0.00e+00	2117.00
IUUC-Laf-053728	Loxodonta africana	77.75	0.00e+00	1885.00
IUUC-Mcc-054971	Macaca mulatta	85.61	0.00e+00	1724.00
IUUC-Meu-056446	Macropus eugenii	79.19	0.00e+00	2016.00
IUUC-Mga-059296	Meleagris gallopavo	95.50	0.00e+00	1945.00
IUUC-Mmr-061232	Microcebus murinus	81.49	0.00e+00	2027.00
IUUC-Mdo-062115	Monodelphis domestica	86.47	0.00e+00	2170.00
IUUC-Mmu-063664	Mus musculus	84.78	0.00e+00	2111.00
IUUC-Mpu-066136	Mustela putorius furo	85.71	0.00e+00	1751.00
IUUC-Mlu-068238	Myotis lucifugus	87.16	0.00e+00	1809.00
IUUC-Nle-069003	Nomascus leucogenys	76.89	0.00e+00	1823.00
IUUC-Ont-072080	Oreochromis niloticus	68.28	0.00e+00	1692.00
IUUC-Oan-072891	Ornithorhynchus anatinus	92.31	0.00e+00	966.00
IUUC-Ocu-074262	Oryctolagus cuniculus	81.43	0.00e+00	1971.00
IUUC-Ola-086538	Oryzias latipes	76.31	0.00e+00	1565.00
IUUC-Oga-088722	Otolemur garnettii	80.70	0.00e+00	2040.00
IUUC-Oar-089249	Ovis aries	89.10	0.00e+00	2123.00
IUUC-Ptr-090752	Pan troglodytes	85.51	0.00e+00	1716.00
IUUC-Pan-092472	Papio anubis	82.31	0.00e+00	1999.00
IUUC-Psi-093335	Pelodiscus sinensis	93.68	0.00e+00	2262.00
IUUC-Pma-094520	Petromyzon marinus	71.95	0.00e+00	1672.00
IUUC-Ppa-095600	Physcomitrella patens	64.36	5.00e-39	152.00
IUUC-Pfo-096526	Poecilia formosa	72.26	0.00e+00	1791.00
IUUC-Pab-098428	Pongo abelii	81.28	0.00e+00	997.00
IUUC-Pca-100233	Procavia capensis	84.72	0.00e+00	750.00
IUUC-Pva-103064	Pteropus vampyrus	72.53	0.00e+00	1754.00
IUUC-Rno-105764	Rattus norvegicus	84.62	0.00e+00	2094.00
IUUC-Sha-106649	Sarcophilus harrisii	86.36	0.00e+00	2185.00
IUUC-Smo-109478	Selaginella moellendorffii	42.83	0.00e+00	956.00
IUUC-Tgu-116870	Taeniopygia guttata	88.21	0.00e+00	2163.00
IUUC-Tru-118661	Takifugu rubripes	71.36	0.00e+00	1824.00
IUUC-Tsy-119640	Tarsius syrichta	70.21	3.00e-177	615.00
IUUC-Tni-120812	Tetraodon nigroviridis	69.18	0.00e+00	1697.00
IUUC-Ttr-128862	Tursiops truncatus	81.00	0.00e+00	2047.00
IUUC-Vpa-130049	Vicugna pacos	73.02	2.00e-142	499.00
IUUC-Xtr-131914	Xenopus tropicalis	84.10	0.00e+00	2040.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence