iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059658

UUCD1 version

UUC-MeG-00689

Ensembl Protein ID

ENSMGAP00000016069.1

UniProt Accession

G1NQH7; G1NQH7_MELGA

Protein Name

Uncharacterized protein

Gene Name

CUL5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000015152.1	ENSMGAT00000017040.1	ENSMGAP00000016069.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/Cullin	3.10e-228	759.1	20	671

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/Cullin

   S: 2    lreavkkilrqesv.kkeyeelytavynlclsk..vgaklYkklkevleefikqvkkkveesedeq.lLktynreWekfreqlkvlrki 86
           +r +v k+lrqesv k+++ +l+++v+++cl++  + ak++++lke++ +fikq++++v +++d++ lLk+y++eW+kf++q+++l+k+
   Q: 20   MRPIVLKLLRQESVtKQQWFDLFSDVHAVCLWDdkGPAKIHQALKEDILDFIKQAQARVLSHQDDTaLLKAYIVEWRKFFTQCDILPKP 108
           7899****************************9999***************************************************** PP
   S: 87   fayldrtyvkk.....skkv..sevrkLaldlwrkeivedikkrllelllklieaeRkgeavdrrllsgvvesl.veLslnk...laiy 164
           f++l+ t ++k     +++v  s vrkL+ld+w+++i+++ik+rl+++++kl++aeR gea+d++l+ gv+es+ v+L++n    l+iy
   Q: 109  FCQLEITLMGKqgsnkKSNVedSIVRKLMLDTWNESIFSNIKNRLQDSAMKLVHAERLGEAFDSQLVIGVRESYaVNLCSNPedkLQIY 197
           ***********8765544448899*************************************************988****99999**** PP
   S: 165  kesFEakfleatqefykaesaeflqenevdeYlkkvearlneeeeraaryleestetk....Llevvekeliakhlesllaelvallrd 249
           +++FE+++l++t++fy++++ ++lq+n+v++Y+k+++a+l+eee+ra ryle+++e++    L+e+++++l++++ e++lae++ ++++
   Q: 198  RDNFEKAYLDSTERFYRTQAPSYLQQNGVQNYMKYADAKLKEEEKRALRYLETRRECNsveaLMECCVNALVTSFKETILAECQGMIKR 286
           ********************************************************999999*************************** PP
   S: 250  kktedlsrmykLlsrvlngleellkeleshikeqgkaalt..aeekekdpkkyVerllelknklqklvseaFnndakFlkaldkafetf 336
           ++te+l++m++L+++v+ng+e++lk+le+hi ++g+a+++  ae++++d++kyVe+ll+l+n+++klv+eaF++d++Fl+a+dka++++
   Q: 287  NETEKLHLMFSLMDKVPNGIEPMLKDLEEHIVSAGLADMVaaAETITTDSEKYVEQLLTLFNRFSKLVKEAFQDDPRFLTARDKAYKAV 375
           ***************************************99999********************************************* PP
   S: 337  vnknsvlka................akspEllAryiDqlLrks..skglteeeleaqldkvllvfkyisekdvFekyYkkhLakRLlsg 407
           vn+++++k+                +k+pEllA+y+D+lLrk+  sk+lt+ee+ea+l++vllv+ky+++kdvF++y+k hL++RL+++
   Q: 376  VNDATIFKLelplkqkgvglktqpeSKCPELLANYCDMLLRKTplSKKLTSEEIEAKLKEVLLVLKYVQNKDVFMRYHKAHLTRRLILD 464
           ***************************************************************************************** PP
   S: 408  ksasseaEesviekLkeec.gaeftskLerMfqdlkvSedlnrqFk.eekenteesesvelsvlvLsagaWptasetekvsLPaelekt 494
           +sa+se+Ee+++e+L+e++ +a++++kL+rMfqd+kvSedln++Fk ++k+n+ + +++++++++L+agaW+++se++ vsLP+ele++
   Q: 465  ISADSEIEENMVEWLREVGmPADYVNKLARMFQDIKVSEDLNQAFKeMHKNNKLALPADSVNIKILNAGAWSRSSEKVFVSLPTELEDL 553
           **********************************************5688888899********************************* PP
   S: 495  iekfeefYlekhsgRkLqWqhtlgraelkaelkkgkyelqVstfQmavLLafnns..ekvsveelkkatelpeeeLrrtlqsLvs.sk. 579
           i+++eefY+++hsgRkL+W+h ++++ +++++++g+y+l+V+tfQ+avL+a+n++  ek+s+e+lk atelp++eLrrtl+sLv+ +k 
   Q: 554  IPEVEEFYKKNHSGRKLHWHHLMSNGIITFKNEVGQYDLEVTTFQLAVLFAWNQRprEKISFENLKLATELPDAELRRTLWSLVAfPKl 642
           ******************************************************999****************************9999 PP
   S: 580  .kqvlkkepeske...ieeedlfsvNqef 604
            +qvl +ep+ ++   ++e++lfsvNqef
   Q: 643  kRQVLLYEPQVNSpkdFTEGTLFSVNQEF 671
           99********977778************9 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

KLQFLKNKGS LQFEDKWDFM RPIVLKLLRQ ESVTKQQWFD LFSDVHAVCL WDDKGPAKIH 60
QALKEDILDF IKQAQARVLS HQDDTALLKA YIVEWRKFFT QCDILPKPFC QLEITLMGKQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAACTGCAGT TCTTAAAGGT AATTCCTAAT AATAATTTAT TTTACTAACA GTACATTACT 60
TTCTTCCTTG TAGAATAAAG GTTCGCTTCA ATTTGAAGAC AAATGGGATT TCATGCGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2

Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8

SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8

Gene Ontology

GO:0031466--C:Cul5-RING ubiquitin ligase complex
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002082	Ailuropoda melanoleuca	98.84	0.00e+00	1543.00
IUUC-Apl-003564	Anas platyrhynchos	99.87	0.00e+00	1552.00
IUUC-Aca-004319	Anolis carolinensis	99.48	0.00e+00	1552.00
IUUC-Ame-011742	Astyanax mexicanus	97.16	0.00e+00	1530.00
IUUC-Bta-012515	Bos taurus	99.47	0.00e+00	1521.00
IUUC-Cel-018522	Caenorhabditis elegans	51.35	0.00e+00	758.00
IUUC-Cja-018785	Callithrix jacchus	99.23	0.00e+00	1551.00
IUUC-Cfa-020932	Canis familiaris	99.34	0.00e+00	1519.00
IUUC-Cpo-022317	Cavia porcellus	99.10	0.00e+00	1550.00
IUUC-Csa-023949	Chlorocebus sabaeus	99.36	0.00e+00	1553.00
IUUC-Cho-024570	Choloepus hoffmanni	98.61	6.00e-126	443.00
IUUC-Cin-025540	Ciona intestinalis	73.02	6.00e-152	529.00
IUUC-Csv-025978	Ciona savignyi	65.10	0.00e+00	1003.00
IUUC-Dre-027958	Danio rerio	96.78	0.00e+00	1533.00
IUUC-Dno-029195	Dasypus novemcinctus	99.36	0.00e+00	1557.00
IUUC-Dor-030573	Dipodomys ordii	87.25	3.00e-173	601.00
IUUC-Dme-032083	Drosophila melanogaster	68.03	0.00e+00	916.00
IUUC-Ete-032428	Echinops telfairi	81.96	0.00e+00	1218.00
IUUC-Eca-033232	Equus caballus	99.23	0.00e+00	1550.00
IUUC-Eeu-035348	Erinaceus europaeus	99.74	0.00e+00	755.00
IUUC-Fca-035401	Felis catus	98.84	0.00e+00	1525.00
IUUC-Fal-037514	Ficedula albicollis	99.74	0.00e+00	1548.00
IUUC-Gmo-038577	Gadus morhua	94.22	0.00e+00	1491.00
IUUC-Gga-041096	Gallus gallus	99.61	0.00e+00	1554.00
IUUC-Gac-042108	Gasterosteus aculeatus	95.12	0.00e+00	1504.00
IUUC-Ggo-045313	Gorilla gorilla	99.35	0.00e+00	1548.00
IUUC-Hsa-045974	Homo sapiens	99.36	0.00e+00	1553.00
IUUC-Itr-049009	Ictidomys tridecemlineatus	99.36	0.00e+00	1552.00
IUUC-Lch-050615	Latimeria chalumnae	99.08	0.00e+00	1514.00
IUUC-Loc-051807	Lepisosteus oculatus	98.20	0.00e+00	1535.00
IUUC-Laf-053601	Loxodonta africana	99.48	0.00e+00	1553.00
IUUC-Mcc-055260	Macaca mulatta	99.36	0.00e+00	1551.00
IUUC-Meu-056632	Macropus eugenii	99.58	0.00e+00	944.00
IUUC-Mmr-061424	Microcebus murinus	89.78	0.00e+00	1348.00
IUUC-Mdo-061836	Monodelphis domestica	99.48	0.00e+00	1552.00
IUUC-Mmu-063757	Mus musculus	97.81	0.00e+00	1533.00
IUUC-Mpu-065823	Mustela putorius furo	99.36	0.00e+00	1552.00
IUUC-Mlu-066969	Myotis lucifugus	99.10	0.00e+00	1545.00
IUUC-Nle-069943	Nomascus leucogenys	99.36	0.00e+00	1553.00
IUUC-Opr-070820	Ochotona princeps	99.31	0.00e+00	861.00
IUUC-Ont-072527	Oreochromis niloticus	95.88	0.00e+00	1511.00
IUUC-Oan-072743	Ornithorhynchus anatinus	99.87	0.00e+00	1524.00
IUUC-Ocu-074586	Oryctolagus cuniculus	99.36	0.00e+00	1553.00
IUUC-Ola-087526	Oryzias latipes	95.88	0.00e+00	1511.00
IUUC-Oga-088425	Otolemur garnettii	94.98	0.00e+00	1514.00
IUUC-Oar-089785	Ovis aries	99.36	0.00e+00	1553.00
IUUC-Ptr-091242	Pan troglodytes	99.36	0.00e+00	1553.00
IUUC-Pan-092246	Papio anubis	99.36	0.00e+00	1553.00
IUUC-Psi-094081	Pelodiscus sinensis	99.87	0.00e+00	1556.00
IUUC-Pma-094735	Petromyzon marinus	82.07	0.00e+00	744.00
IUUC-Pfo-096357	Poecilia formosa	95.36	0.00e+00	1506.00
IUUC-Pab-098248	Pongo abelii	93.17	0.00e+00	1437.00
IUUC-Pca-100756	Procavia capensis	88.08	0.00e+00	874.00
IUUC-Pva-102990	Pteropus vampyrus	85.04	0.00e+00	900.00
IUUC-Rno-105887	Rattus norvegicus	98.07	0.00e+00	1534.00
IUUC-Sha-107016	Sarcophilus harrisii	99.48	0.00e+00	1552.00
IUUC-Sar-113558	Sorex araneus	93.66	0.00e+00	1477.00
IUUC-Ssc-115414	Sus scrofa	99.36	0.00e+00	1553.00
IUUC-Tgu-116801	Taeniopygia guttata	99.23	0.00e+00	1542.00
IUUC-Tru-117565	Takifugu rubripes	96.14	0.00e+00	1517.00
IUUC-Tsy-119292	Tarsius syrichta	93.48	0.00e+00	1368.00
IUUC-Tni-120471	Tetraodon nigroviridis	96.27	0.00e+00	1520.00
IUUC-Tbe-127838	Tupaia belangeri	93.56	0.00e+00	1483.00
IUUC-Ttr-128345	Tursiops truncatus	98.84	0.00e+00	1545.00
IUUC-Vpa-130191	Vicugna pacos	90.15	0.00e+00	838.00
IUUC-Xtr-132810	Xenopus tropicalis	98.97	0.00e+00	1546.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence