iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tni-120471

UUCD1 version

UUC-TeN-01018

Ensembl Protein ID

ENSTNIP00000006310.1

UniProt Accession

H3CDI7; H3CDI7_TETNG

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000003711.1	ENSTNIT00000006459.1	ENSTNIP00000006310.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/Cullin	6.00e-225	748.8	22	673

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/Cullin

   S: 2    lreavkkilrqesv.kkeyeelytavynlclsk..vgaklYkklkevleefikqvkkkveesedeq.lLktynreWekfreqlkvlrki 86
           +r +v k+lrqesv k+++ +l+++v+++cl++  + ak++++lke++ +fikq++++v +++d++ lLk+y++eW+kf++q+++l+k+
   Q: 22   MRPIVLKLLRQESVtKQQWFDLFSDVHAVCLWDdkGPAKIHQALKEDILDFIKQAQARVLSHQDDTaLLKAYIVEWRKFFTQCDILPKP 110
           6899****************************9999***************************************************** PP
   S: 87   fayldrtyvkk.....skkv..sevrkLaldlwrkeivedikkrllelllklieaeRkgeavdrrllsgvvesl.veLslnk...laiy 164
           f++l+ t ++k     +++v  s vrkL+ld+w+++i+++ik+rl+++++kl++aeR gea+d++l+ gv+es+ v+L++n    l+iy
   Q: 111  FCQLEITLMGKqgsnkKSNVedSIVRKLMLDTWNESIFSNIKNRLQDSAMKLVHAERLGEAFDSQLVIGVRESYaVNLCSNPddkLQIY 199
           ***********8765544448899*************************************************988****99999**** PP
   S: 165  kesFEakfleatqefykaesaeflqenevdeYlkkvearlneeeeraaryleestetk....Llevvekeliakhlesllaelvallrd 249
           +++FE++++++t++fy++++ ++lq+n+v++Y+k+++++l+eee+ra ryle+++ ++    L+e+++++l++++ e++lae++ ++++
   Q: 200  RDNFEKAYMDSTERFYRTQAPAYLQQNGVQNYMKYADSKLREEEKRALRYLETRRDCNsvqaLMECCVNALVTSFKETILAECPGMIKR 288
           *******************************************************9999999*************************** PP
   S: 250  kktedlsrmykLlsrvlngleellkeleshikeqgkaalt..aeekekdpkkyVerllelknklqklvseaFnndakFlkaldkafetf 336
           ++te+l++m++L+++v+ g+e++lk+le+hi+++g+a+++  ae+++ d++kyVe+ll+l+n++++lv+eaF++d++Fl+a+dka++++
   Q: 289  NETEKLHLMFSLMDKVPCGIEPMLKDLEEHIMSAGLADMVasAETITSDSEKYVEQLLTLFNRFSRLVKEAFQDDPRFLTARDKAYKAV 377
           ***************************************9999999******************************************* PP
   S: 337  vnknsvlka................akspEllAryiDqlLrks..skglteeeleaqldkvllvfkyisekdvFekyYkkhLakRLlsg 407
           vn+++++k+                +k+pEllA+y+D+lLrk+  sk+lt+ee+ea+l++vllv+ky+++kdvF++y+k hL++RL+++
   Q: 378  VNDATIFKLelpmkqkgvglktqpeSKCPELLANYCDMLLRKTplSKKLTSEEIEAKLKEVLLVLKYVQNKDVFMRYHKAHLTRRLILD 466
           ***************************************************************************************** PP
   S: 408  ksasseaEesviekLkeec.gaeftskLerMfqdlkvSedlnrqFk.eekenteesesvelsvlvLsagaWptasetekvsLPaelekt 494
           +sa+se+Ee+++e+L+e++ +a++++kL+rMfqd+kvSedln+ Fk ++k+n+ + +++++++++L+agaW+++se++ vsLP+ele++
   Q: 467  ISADSEIEENMVEWLREVGmPADYVNKLARMFQDIKVSEDLNQSFKeMHKHNKLALPADSVNIKILNAGAWSRSSEKVFVSLPTELEDL 555
           **********************************************5678888899********************************* PP
   S: 495  iekfeefYlekhsgRkLqWqhtlgraelkaelkkgkyelqVstfQmavLLafnns..ekvsveelkkatelpeeeLrrtlqsLvs.sk. 579
           i+++e fY+++hsgRkL+W+h ++++ +++++++g+y+l+V+tfQ+avL+a+n++  e++s+e+lk atelp++eLrrtl+sLv+ +k 
   Q: 556  IPEVEDFYKKNHSGRKLHWHHLMSNGIITFKNEVGQYDLEVTTFQLAVLFAWNQRprERISFENLKLATELPDAELRRTLWSLVAfPKl 644
           ******************************************************999****************************9999 PP
   S: 580  .kqvlkkepeske...ieeedlfsvNqef 604
            +qvl +ep  ++   ++e++lfsvNq+f
   Q: 645  kRQVLLYEPLVSSpkdFTEGTLFSVNQDF 673
           99*******9876677***********99 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

MATSHLLKNK GSLQFEDKWD LMRPIVLKLL RQESVTKQQW FDLFSDVHAV CLWDDKGPAK 60
IHQALKEDIL DFIKQAQARV LSHQDDTALL KAYIVEWRKF FTQCDILPKP FCQLEITLMG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGACGT CTCATTTGCT AAAGGTAGGA GCCACTTCAA TTCAATTTTT GAAATTAAAT 60
GTTGCCTGAA GTTCTTGTCA CTTTAATGAC GCGGTGCCAG CATCTTACTG GAACCTTAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2

Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8

SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8

Gene Ontology

GO:0031461--C:cullin-RING ubiquitin ligase complex
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002082	Ailuropoda melanoleuca	95.13	0.00e+00	1507.00
IUUC-Apl-003564	Anas platyrhynchos	96.38	0.00e+00	1512.00
IUUC-Aca-004319	Anolis carolinensis	96.03	0.00e+00	1520.00
IUUC-Ame-011742	Astyanax mexicanus	97.06	0.00e+00	1537.00
IUUC-Bta-012515	Bos taurus	96.32	0.00e+00	1485.00
IUUC-Cel-018522	Caenorhabditis elegans	50.90	0.00e+00	752.00
IUUC-Cja-018785	Callithrix jacchus	96.03	0.00e+00	1520.00
IUUC-Cfa-020932	Canis familiaris	96.18	0.00e+00	1483.00
IUUC-Cpo-022317	Cavia porcellus	96.16	0.00e+00	1523.00
IUUC-Csa-023949	Chlorocebus sabaeus	96.16	0.00e+00	1523.00
IUUC-Cho-024570	Choloepus hoffmanni	95.37	3.00e-123	435.00
IUUC-Cin-025540	Ciona intestinalis	73.57	1.00e-151	528.00
IUUC-Csv-025978	Ciona savignyi	65.36	0.00e+00	998.00
IUUC-Dre-027958	Danio rerio	96.16	0.00e+00	1534.00
IUUC-Dno-029195	Dasypus novemcinctus	96.13	0.00e+00	1513.00
IUUC-Dor-030573	Dipodomys ordii	84.64	3.00e-169	588.00
IUUC-Dme-032083	Drosophila melanogaster	67.93	0.00e+00	919.00
IUUC-Ete-032428	Echinops telfairi	79.13	0.00e+00	1189.00
IUUC-Eca-033232	Equus caballus	96.03	0.00e+00	1520.00
IUUC-Eeu-035348	Erinaceus europaeus	96.90	0.00e+00	738.00
IUUC-Fca-035401	Felis catus	95.62	0.00e+00	1488.00
IUUC-Fal-037514	Ficedula albicollis	96.38	0.00e+00	1509.00
IUUC-Gmo-038577	Gadus morhua	96.30	0.00e+00	1528.00
IUUC-Gga-041096	Gallus gallus	96.01	0.00e+00	1510.00
IUUC-Gac-042108	Gasterosteus aculeatus	97.70	0.00e+00	1548.00
IUUC-Ggo-045313	Gorilla gorilla	95.65	0.00e+00	1517.00
IUUC-Hsa-045974	Homo sapiens	96.16	0.00e+00	1523.00
IUUC-Itr-049009	Ictidomys tridecemlineatus	96.16	0.00e+00	1519.00
IUUC-Lch-050615	Latimeria chalumnae	96.71	0.00e+00	1489.00
IUUC-Loc-051807	Lepisosteus oculatus	96.29	0.00e+00	1519.00
IUUC-Laf-053601	Loxodonta africana	96.13	0.00e+00	1513.00
IUUC-Mcc-055260	Macaca mulatta	96.16	0.00e+00	1521.00
IUUC-Meu-056632	Macropus eugenii	96.47	0.00e+00	929.00
IUUC-Mga-059658	Meleagris gallopavo	96.27	0.00e+00	1519.00
IUUC-Mmr-061424	Microcebus murinus	87.06	0.00e+00	1326.00
IUUC-Mdo-061836	Monodelphis domestica	96.29	0.00e+00	1523.00
IUUC-Mmu-063757	Mus musculus	94.88	0.00e+00	1505.00
IUUC-Mpu-065823	Mustela putorius furo	96.03	0.00e+00	1521.00
IUUC-Mlu-066969	Myotis lucifugus	95.75	0.00e+00	1507.00
IUUC-Nle-069943	Nomascus leucogenys	96.16	0.00e+00	1523.00
IUUC-Opr-070820	Ochotona princeps	96.34	0.00e+00	841.00
IUUC-Ont-072527	Oreochromis niloticus	98.72	0.00e+00	1553.00
IUUC-Oan-072743	Ornithorhynchus anatinus	96.45	0.00e+00	1486.00
IUUC-Ocu-074586	Oryctolagus cuniculus	96.16	0.00e+00	1523.00
IUUC-Ola-087526	Oryzias latipes	95.65	0.00e+00	1518.00
IUUC-Oga-088425	Otolemur garnettii	91.63	0.00e+00	1473.00
IUUC-Oar-089785	Ovis aries	96.16	0.00e+00	1523.00
IUUC-Ptr-091242	Pan troglodytes	96.16	0.00e+00	1523.00
IUUC-Pan-092246	Papio anubis	96.16	0.00e+00	1523.00
IUUC-Psi-094081	Pelodiscus sinensis	96.39	0.00e+00	1514.00
IUUC-Pma-094735	Petromyzon marinus	81.61	0.00e+00	742.00
IUUC-Pfo-096357	Poecilia formosa	97.44	0.00e+00	1536.00
IUUC-Pab-098248	Pongo abelii	90.01	0.00e+00	1407.00
IUUC-Pca-100756	Procavia capensis	85.38	0.00e+00	850.00
IUUC-Pva-102990	Pteropus vampyrus	82.36	0.00e+00	887.00
IUUC-Rno-105887	Rattus norvegicus	95.26	0.00e+00	1510.00
IUUC-Sha-107016	Sarcophilus harrisii	96.29	0.00e+00	1523.00
IUUC-Sar-113558	Sorex araneus	90.43	0.00e+00	1438.00
IUUC-Ssc-115414	Sus scrofa	96.16	0.00e+00	1523.00
IUUC-Tgu-116801	Taeniopygia guttata	95.39	0.00e+00	1500.00
IUUC-Tru-117565	Takifugu rubripes	99.49	0.00e+00	1565.00
IUUC-Tsy-119292	Tarsius syrichta	90.35	0.00e+00	1330.00
IUUC-Tbe-127838	Tupaia belangeri	90.40	0.00e+00	1453.00
IUUC-Ttr-128345	Tursiops truncatus	95.90	0.00e+00	1517.00
IUUC-Vpa-130191	Vicugna pacos	87.97	0.00e+00	832.00
IUUC-Xtr-132810	Xenopus tropicalis	96.29	0.00e+00	1523.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence