iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cja-019633

Ensembl Protein ID

ENSCJAP00000049739.1

UniProt Accession

F6URJ1; F6URJ1_CALJA

Genbank Protein ID

ENSCJAP00000049739

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACFV01087973

Gene Name

NOD2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000001786.3	ENSCJAT00000058608.1	ENSCJAP00000049739.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	6.10e-20	72.5	158	211

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 3    eeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaae 56
           +e+rl+++t+++r+r+lLd+++v++++l++fll++++el+++ a + +++++++
   Q: 158  DEIRLPIFTPSQRARRLLDLATVKANGLAAFLLQHVQELPVPLALPLEAATCKK 211
           8***************************************************93 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MRRKEQVSSL EHSPGCEMCS QEAFQAQRSQ LVELLVSGSL EGFESVLDWL LSWEVLSWED 60
YEGFHILGQP LSHLARRLLD TVWNKGTWAC QKLITAVQEV QADSRTPKLH GCWHPYSLHP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCCGGGCTC GCCAGTCCTG TGCCACTGGG CATTTGGCAT TCTGCACAAG GCCCATCCAC 60
AGATGCCATG CCTGCTTCCC CAGCCTAGTG GGCTTTGATG GAGGAAGAGG GGTGGTCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR007109--Brix
IPR001315--CARD
IPR011029--DEATH-like_dom
IPR007111--NACHT_NTPase
IPR027417--P-loop_NTPase

PROSITE

PS50209--CARD
PS50837--NACHT

Pfam

PF00619--CARD

Gene Ontology

GO:0016323--C:basolateral plasma membrane
GO:0009986--C:cell surface
GO:0008180--C:COP9 signalosome
GO:0005856--C:cytoskeleton
GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0031982--C:vesicle
GO:0005524--F:ATP binding
GO:0032500--F:muramyl dipeptide binding
GO:0042834--F:peptidoglycan binding
GO:0071225--P:cellular response to muramyl dipeptide
GO:0002374--P:cytokine secretion involved in immune response
GO:0042742--P:defense response to bacterium
GO:0016045--P:detection of bacterium
GO:0032498--P:detection of muramyl dipeptide
GO:0045087--P:innate immune response
GO:0030277--P:maintenance of gastrointestinal epithelium
GO:0070431--P:nucleotide-binding oligomerization domain containing 2 signaling pathway
GO:0050871--P:positive regulation of B cell activation
GO:1900017--P:positive regulation of cytokine production involved in inflammatory response
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0050718--P:positive regulation of interleukin-1 beta secretion
GO:0032740--P:positive regulation of interleukin-17 production
GO:0032755--P:positive regulation of interleukin-6 production
GO:0032757--P:positive regulation of interleukin-8 production
GO:0046330--P:positive regulation of JNK cascade
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:1901224--P:positive regulation of NIK/NF-kappaB signaling
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0032760--P:positive regulation of tumor necrosis factor production
GO:0002830--P:positive regulation of type 2 immune response
GO:0042981--P:regulation of apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001822	Ailuropoda melanoleuca	77.62	0.00e+00	1083.00
IUUC-Ame-011021	Astyanax mexicanus	44.65	0.00e+00	657.00
IUUC-Bta-013241	Bos taurus	77.48	0.00e+00	1181.00
IUUC-Cfa-020039	Canis familiaris	79.12	0.00e+00	1190.00
IUUC-Cpo-022337	Cavia porcellus	76.50	0.00e+00	1196.00
IUUC-Csa-023906	Chlorocebus sabaeus	90.54	0.00e+00	1372.00
IUUC-Dre-027568	Danio rerio	45.25	5.00e-179	621.00
IUUC-Dno-029098	Dasypus novemcinctus	77.16	0.00e+00	1095.00
IUUC-Dor-031102	Dipodomys ordii	71.25	0.00e+00	665.00
IUUC-Ete-032943	Echinops telfairi	76.73	0.00e+00	826.00
IUUC-Eca-034310	Equus caballus	81.00	0.00e+00	1199.00
IUUC-Eeu-034589	Erinaceus europaeus	73.30	4.00e-156	545.00
IUUC-Fca-036252	Felis catus	78.09	0.00e+00	780.00
IUUC-Gac-041442	Gasterosteus aculeatus	44.57	0.00e+00	629.00
IUUC-Ggo-044861	Gorilla gorilla	91.16	0.00e+00	1374.00
IUUC-Hsa-046093	Homo sapiens	91.41	0.00e+00	1382.00
IUUC-Itr-048543	Ictidomys tridecemlineatus	78.32	0.00e+00	1132.00
IUUC-Lch-049454	Latimeria chalumnae	49.92	0.00e+00	640.00
IUUC-Laf-053553	Loxodonta africana	80.25	0.00e+00	1159.00
IUUC-Mcc-055772	Macaca mulatta	90.77	0.00e+00	1363.00
IUUC-Meu-056785	Macropus eugenii	67.79	5.00e-108	385.00
IUUC-Mmr-060596	Microcebus murinus	81.09	0.00e+00	1189.00
IUUC-Mdo-062983	Monodelphis domestica	64.64	0.00e+00	773.00
IUUC-Mmu-063951	Mus musculus	74.91	0.00e+00	1140.00
IUUC-Mpu-066412	Mustela putorius furo	79.12	0.00e+00	1177.00
IUUC-Mlu-067601	Myotis lucifugus	77.96	0.00e+00	1050.00
IUUC-Nle-069913	Nomascus leucogenys	90.39	0.00e+00	1077.00
IUUC-Opr-070999	Ochotona princeps	80.75	0.00e+00	928.00
IUUC-Ont-072512	Oreochromis niloticus	44.94	0.00e+00	654.00
IUUC-Oan-073564	Ornithorhynchus anatinus	58.31	0.00e+00	826.00
IUUC-Ocu-074837	Oryctolagus cuniculus	83.12	0.00e+00	1206.00
IUUC-Ola-086555	Oryzias latipes	43.26	3.00e-171	595.00
IUUC-Oga-088909	Otolemur garnettii	80.84	0.00e+00	1217.00
IUUC-Oar-089315	Ovis aries	77.26	0.00e+00	1151.00
IUUC-Ptr-090542	Pan troglodytes	91.16	0.00e+00	1374.00
IUUC-Pan-092545	Papio anubis	90.78	0.00e+00	1362.00
IUUC-Pma-094167	Petromyzon marinus	34.07	8.00e-63	234.00
IUUC-Pfo-096976	Poecilia formosa	43.78	2.00e-176	613.00
IUUC-Pab-098481	Pongo abelii	90.91	0.00e+00	1365.00
IUUC-Pca-100135	Procavia capensis	73.18	0.00e+00	925.00
IUUC-Pva-102127	Pteropus vampyrus	77.13	0.00e+00	1028.00
IUUC-Pgr-103409	Puccinia graminis	39.47	1.50e+00	26.90
IUUC-Rno-105783	Rattus norvegicus	77.11	0.00e+00	1149.00
IUUC-Sar-113448	Sorex araneus	72.62	0.00e+00	880.00
IUUC-Tru-118708	Takifugu rubripes	42.89	2.00e-165	576.00
IUUC-Tni-120172	Tetraodon nigroviridis	36.18	2.00e-31	129.00
IUUC-Tbe-127661	Tupaia belangeri	86.08	2.00e-142	500.00
IUUC-Ttr-128318	Tursiops truncatus	75.59	0.00e+00	1058.00
IUUC-Vpa-130502	Vicugna pacos	74.47	6.00e-159	555.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence