iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-067019

Ensembl Protein ID

ENSMLUP00000000199.2

UniProt Accession

G1NSS9; G1NSS9_MYOLU

Genbank Protein ID

ENSMLUP00000000199

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02028850

Gene Name

ATG16L2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000000211.2	ENSMLUT00000000217.2	ENSMLUP00000000199.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-27	95.1	340	375
UBD/Beta-Prp	6.20e-44	150.4	338	620

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           H ++v++++f ++  ll++G+ D  i++W++  g+l
   Q: 340  HLSEVNAVRFgPNsSLLATGGADRLIHLWNVVGGRL 375
           99*********7779***************987765 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgh 93
           ++h s +++v f p++sllatg++d+ i +w+v  g l   ++l+g  + +t+v+f+p+g+  + +   +++++w +       tl+gh
   Q: 338  DAHLSEVNAVRFGPNSSLLATGGADRLIHLWNVVGGRLeaNQTLEGAGSSITSVDFDPSGSQVLAATYSQAAQLWKVGEALSKETLSGH 426
           6899999*******************************88899******************999999999******************* PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtds 182
           +d+v++ +f  +++  v+Gs+drt++ wdl+  +c++ t ++ +    c  v + + +++sG++D+++r+Wd++   + +      +++
   Q: 427  TDKVTAAKFKLTRHQAVTGSRDRTVKEWDLDRAYCSR-TINVLS---YCNDVVCGDHVIISGHNDQKIRFWDSRVPHCTQVIP--VQGR 509
           ************************************9.666665...4555555556*************************5..589* PP
   S: 183  vyslsfdsngkelvsgsldgtvklwdlqtgec.....vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnss 266
           v+sls+++++ +l+s+s+d+t+k+ dl+ +++      + +++ +d++k   fsp+  + + gs Dg ++iWd+++g+l ++l +++ +
   Q: 510  VTSLSLSHDQLHLLSCSRDNTLKVIDLRVSNIrqvfrADGFKCGSDWTK-AVFSPDRSFALAGSWDGALYIWDVDTGKLESSLRGPHCN 597
           ****************************888833334444555556666.8899*********************************88 PP
   S: 267  visvavlsfgdnvlvlgsedskvniw 292
            ++ ++   ++n++v++++ +kv +w
   Q: 598  AVAWCC---SGNHVVSVDQAGKVVLW 620
           888777...99*************99 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

SAAMAGPCGA GAPAARWKRH IVRQLRQRDR TQKALFLELV PAYNRLLEKA ELLARFSDKL 60
QPEPNDVTPV PHQGPWEEES QSNSDQVPSP DILRVKWQEE KEGLRLVCGE MAYQVVEKTA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCGCGGCCA TGGCGGGGCC CTGCGGCGCC GGAGCGCCCG CCGCCCGCTG GAAGCGCCAC 60
ATCGTGCGGC AGCTGCGGCA GCGGGACCGC ACGCAGAAGG CGCTCTTCCT GGAGCTGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0039689--P:negative stranded viral RNA replication

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001470	Ailuropoda melanoleuca	68.58	0.00e+00	747.00
IUUC-Atr-003073	Amborella trichopoda	32.12	1.00e-27	117.00
IUUC-Aca-004664	Anolis carolinensis	71.37	2.00e-97	348.00
IUUC-Ame-011152	Astyanax mexicanus	43.03	2.00e-116	412.00
IUUC-Bta-013118	Bos taurus	84.54	0.00e+00	918.00
IUUC-Cja-020002	Callithrix jacchus	83.39	0.00e+00	894.00
IUUC-Cfa-020878	Canis familiaris	83.01	0.00e+00	917.00
IUUC-Cpo-022476	Cavia porcellus	80.42	0.00e+00	854.00
IUUC-Csa-024134	Chlorocebus sabaeus	84.43	0.00e+00	908.00
IUUC-Cho-024853	Choloepus hoffmanni	68.54	4.00e-164	571.00
IUUC-Dre-027949	Danio rerio	42.72	1.00e-128	453.00
IUUC-Dno-029683	Dasypus novemcinctus	81.89	0.00e+00	726.00
IUUC-Dor-030897	Dipodomys ordii	75.97	0.00e+00	893.00
IUUC-Ete-032957	Echinops telfairi	92.83	1.00e-126	447.00
IUUC-Eca-033303	Equus caballus	88.89	1.00e-158	551.00
IUUC-Eeu-035336	Erinaceus europaeus	73.51	7.00e-147	514.00
IUUC-Fca-036232	Felis catus	86.20	0.00e+00	993.00
IUUC-Gmo-038880	Gadus morhua	50.00	8.00e-70	258.00
IUUC-Gac-042500	Gasterosteus aculeatus	39.74	3.00e-85	309.00
IUUC-Ggo-045130	Gorilla gorilla	86.39	0.00e+00	654.00
IUUC-Hsa-046359	Homo sapiens	86.04	0.00e+00	888.00
IUUC-Itr-048780	Ictidomys tridecemlineatus	82.52	0.00e+00	912.00
IUUC-Lch-050669	Latimeria chalumnae	53.61	4.00e-92	331.00
IUUC-Loc-052789	Lepisosteus oculatus	43.80	1.00e-113	403.00
IUUC-Laf-053699	Loxodonta africana	83.36	0.00e+00	895.00
IUUC-Mcc-055657	Macaca mulatta	79.23	0.00e+00	816.00
IUUC-Meu-056639	Macropus eugenii	47.95	7.00e-98	351.00
IUUC-Mmr-061314	Microcebus murinus	77.01	0.00e+00	814.00
IUUC-Mdo-061841	Monodelphis domestica	64.10	0.00e+00	664.00
IUUC-Mmu-064065	Mus musculus	81.09	0.00e+00	918.00
IUUC-Mpu-066742	Mustela putorius furo	83.71	0.00e+00	913.00
IUUC-Nle-069037	Nomascus leucogenys	84.40	0.00e+00	926.00
IUUC-Opr-071039	Ochotona princeps	78.26	0.00e+00	845.00
IUUC-Oan-073431	Ornithorhynchus anatinus	71.60	1.00e-133	469.00
IUUC-Ocu-074772	Oryctolagus cuniculus	82.08	0.00e+00	795.00
IUUC-Ola-086964	Oryzias latipes	51.92	9.00e-81	293.00
IUUC-Oga-088188	Otolemur garnettii	81.94	0.00e+00	850.00
IUUC-Oar-090231	Ovis aries	78.16	0.00e+00	892.00
IUUC-Ptr-091434	Pan troglodytes	83.28	0.00e+00	842.00
IUUC-Pan-091868	Papio anubis	83.57	0.00e+00	900.00
IUUC-Psi-093652	Pelodiscus sinensis	62.65	4.00e-154	537.00
IUUC-Pfo-096960	Poecilia formosa	41.80	3.00e-96	345.00
IUUC-Pab-097776	Pongo abelii	85.06	0.00e+00	836.00
IUUC-Pca-100220	Procavia capensis	64.74	2.00e-170	592.00
IUUC-Pva-103135	Pteropus vampyrus	88.10	0.00e+00	900.00
IUUC-Rno-105529	Rattus norvegicus	80.45	0.00e+00	958.00
IUUC-Sha-107062	Sarcophilus harrisii	63.91	0.00e+00	704.00
IUUC-Sar-113109	Sorex araneus	65.60	5.00e-126	444.00
IUUC-Ssc-115271	Sus scrofa	84.08	0.00e+00	890.00
IUUC-Tni-120373	Tetraodon nigroviridis	52.23	1.00e-82	299.00
IUUC-Ttr-128267	Tursiops truncatus	86.50	0.00e+00	686.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence