iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-027496

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

F-box and WD repeat domain-containing 10

Genbank Nucleotide ID

CR752650

Gene Name

fbxw10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000086484.2	ENSDART00000123825.2	ENSDARP00000112164.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-29	101.8	206	241
UBD/Beta-Prp	9.90e-45	153.9	131	390

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDlrtgvll 36
           gH + ++cl++   ++lvsG+ D+ +kvW+l tg+++
   Q: 206  GHFGTINCLDLvG-DRLVSGAKDCRVKVWNLQTGKCV 241
           7999*******53.79*******************97 PP

UBD/Beta-Prp

   S: 17   kfspdksllatgsrdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp 104
           ++  +++l+a+gsrd+ti++  + + k l  + +gh++ v+av   +++++ +++s D  i+ w+l+tg c+++++gh  ++ +l++  
   Q: 131  HY-AGGQLVAVGSRDRTIRLLHIGSLKELPLViQGHSGSVRAVLVCEEKDLVISASYDLSIRCWNLKTGMCMMIFHGHFGTINCLDLVG 218
           44.689**************9999988777667*******************************************************9 PP
   S: 105  sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngk 193
             d+lvsG +d  ++vw+l+tg+c+e+++ +h + ++cv++++   l++s++  +++r+W+++t+ l+r+ +g h+++v +l fd+   
   Q: 219  --DRLVSGAKDCRVKVWNLQTGKCVENLKFKHPKPIMCVKMSE--TLVISSCSGGQIRIWSIQTALLIRQISG-HQGAVLCLCFDQ--W 300
           ..*****************************************..***************************9.************..8 PP
   S: 194  elvsgsldgtvklwdlq..tgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvl 280
           +++sg+ dg vk w++    ++c+rt++  ++ v+ + f+    r+++g +Dg iri++  +gd+l++++  n +  +v  l+  +n +
   Q: 301  HILSGGSDGVVKAWSINssFKKCLRTFQHPKE-VLAMSFL--FLRIITGCMDGKIRIFNFLNGDCLRVIKT-NMKQCPVLSLHTHHNTV 385
           *****************87799****986665.5556666..59*************************98.44666666667777777 PP
   S: 281  vlgse 285
           v  + 
   Q: 386  VVNTR 390
           66554 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MTLGQLDKVS LSSCRRVSKH WQSLTEEILT EMEVKKRVKK QAMIFQGNST SKVNPVYAKI 60
CEVLVPISEG DKHFQHGGTS PRHTQSQGQV LDSLYKGFKT EKIQLEERNV YCGVYNTSVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTAAAGGACT CCAAATCTCT GAAGAGTATC TGTAATCAGG TTGAGCTGGA CTCAGACAGT 60
TGTGATGGTC CTGATCCTGC CCTCACCGTC GTTCCCAGGT CATCAAAATC CCTGTCGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

KEGG

dre:563998

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001837	Ailuropoda melanoleuca	43.94	6.00e-88	319.00
IUUC-Apl-003572	Anas platyrhynchos	43.54	1.00e-104	374.00
IUUC-Aca-004297	Anolis carolinensis	35.41	2.00e-114	407.00
IUUC-Ame-011058	Astyanax mexicanus	59.22	2.00e-146	513.00
IUUC-Bta-012667	Bos taurus	41.99	2.00e-84	307.00
IUUC-Cja-019163	Callithrix jacchus	44.33	2.00e-112	400.00
IUUC-Cfa-020784	Canis familiaris	45.19	2.00e-116	413.00
IUUC-Cpo-021429	Cavia porcellus	42.90	1.00e-84	308.00
IUUC-Csa-023597	Chlorocebus sabaeus	45.05	2.00e-103	370.00
IUUC-Cho-024559	Choloepus hoffmanni	37.23	1.00e-31	131.00
IUUC-Dno-028995	Dasypus novemcinctus	34.39	3.00e-120	426.00
IUUC-Ete-032823	Echinops telfairi	43.01	8.00e-43	169.00
IUUC-Eca-033666	Equus caballus	36.68	4.00e-113	403.00
IUUC-Fca-035589	Felis catus	36.26	1.00e-113	405.00
IUUC-Fal-037403	Ficedula albicollis	42.54	2.00e-98	353.00
IUUC-Gmo-038669	Gadus morhua	48.92	2.00e-62	233.00
IUUC-Gga-041227	Gallus gallus	44.02	3.00e-106	380.00
IUUC-Hsa-046221	Homo sapiens	44.42	4.00e-112	399.00
IUUC-Itr-049011	Ictidomys tridecemlineatus	43.21	4.00e-107	383.00
IUUC-Lch-050046	Latimeria chalumnae	35.27	8.00e-121	428.00
IUUC-Loc-052366	Lepisosteus oculatus	55.73	5.00e-149	521.00
IUUC-Laf-053745	Loxodonta africana	45.48	5.00e-118	419.00
IUUC-Mcc-054826	Macaca mulatta	36.41	2.00e-112	400.00
IUUC-Meu-056636	Macropus eugenii	46.15	2.00e-24	108.00
IUUC-Mga-060185	Meleagris gallopavo	41.83	3.00e-104	373.00
IUUC-Mdo-062382	Monodelphis domestica	44.20	2.00e-107	384.00
IUUC-Mmu-063623	Mus musculus	43.88	4.00e-108	386.00
IUUC-Mpu-066872	Mustela putorius furo	37.27	1.00e-114	407.00
IUUC-Mlu-067552	Myotis lucifugus	42.22	7.00e-84	305.00
IUUC-Nle-069247	Nomascus leucogenys	44.96	3.00e-112	399.00
IUUC-Opr-070455	Ochotona princeps	42.86	2.00e-84	307.00
IUUC-Ont-071926	Oreochromis niloticus	40.62	1.00e-126	447.00
IUUC-Oan-073411	Ornithorhynchus anatinus	40.10	1.00e-92	334.00
IUUC-Ocu-073893	Oryctolagus cuniculus	44.94	2.00e-115	411.00
IUUC-Oga-087937	Otolemur garnettii	43.94	4.00e-85	309.00
IUUC-Oar-089680	Ovis aries	40.21	2.00e-111	397.00
IUUC-Ptr-091549	Pan troglodytes	40.05	2.00e-90	327.00
IUUC-Pan-091904	Papio anubis	44.47	4.00e-111	396.00
IUUC-Psi-093181	Pelodiscus sinensis	44.93	8.00e-105	375.00
IUUC-Pma-094711	Petromyzon marinus	47.54	1.00e-71	263.00
IUUC-Pab-098067	Pongo abelii	44.96	1.00e-112	401.00
IUUC-Pca-100867	Procavia capensis	53.27	8.00e-76	278.00
IUUC-Pva-102209	Pteropus vampyrus	45.69	2.00e-107	383.00
IUUC-Rno-105374	Rattus norvegicus	45.01	4.00e-102	366.00
IUUC-Sha-107459	Sarcophilus harrisii	49.24	6.00e-42	165.00
IUUC-Tgu-117261	Taeniopygia guttata	41.49	3.00e-88	318.00
IUUC-Tru-117705	Takifugu rubripes	49.69	9.00e-47	179.00
IUUC-Tni-120365	Tetraodon nigroviridis	52.91	8.00e-48	183.00
IUUC-Tbe-128015	Tupaia belangeri	43.83	4.00e-99	355.00
IUUC-Ttr-128654	Tursiops truncatus	44.62	2.00e-106	379.00
IUUC-Vpa-130176	Vicugna pacos	32.62	2.00e-65	244.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence