iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gac-041854

Ensembl Protein ID

ENSGACP00000009577.1

UniProt Accession

G3NW58; G3NW58_GASAC

Protein Name

Tyrosine-protein kinase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000007232.1	ENSGACT00000009597.1	ENSGACP00000009577.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.10e-14	53.6	57	112

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           +++v ++y+ye+++d++L ++kGd++++i  ++ d +W  +++  +g+rG +P+nFv+
   Q: 57   DNLVVAIYSYEPTHDGDLGFEKGDTLKII--NKDDPEWYLAESLITGQRGYIPHNFVA 112
           5789*************************..8899*********************97 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

MGCNCSSDYS DGEWMENLDE ICEHCSCPIP PQSCNPYTDQ LTPYPAQHSP PTSPLPDNLV 60
VAIYSYEPTH DGDLGFEKGD TLKIINKDDP EWYLAESLIT GQRGYIPHNF VAMTTVETEP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGCGCGTAC AGACGCACAG CACGGCACCT CGAGCGCAGA GATAGTTATA ATAAGAGAAG 60
CGGACGATGA TTTCTCGAAA CCCGGGCTCC GGATAACTGT TCAATCAAGA ATATCTCTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001315	Ailuropoda melanoleuca	65.19	0.00e+00	717.00
IUUC-Ame-010831	Astyanax mexicanus	76.36	0.00e+00	709.00
IUUC-Bta-013264	Bos taurus	68.63	0.00e+00	731.00
IUUC-Cfa-021161	Canis familiaris	65.00	0.00e+00	716.00
IUUC-Cpo-022492	Cavia porcellus	69.02	0.00e+00	733.00
IUUC-Dre-028005	Danio rerio	75.75	0.00e+00	778.00
IUUC-Dno-029365	Dasypus novemcinctus	66.27	0.00e+00	687.00
IUUC-Dor-030892	Dipodomys ordii	66.27	0.00e+00	693.00
IUUC-Eca-033325	Equus caballus	67.32	0.00e+00	705.00
IUUC-Eeu-035004	Erinaceus europaeus	60.67	1.00e-156	545.00
IUUC-Fca-035908	Felis catus	68.82	0.00e+00	731.00
IUUC-Gmo-038984	Gadus morhua	76.39	0.00e+00	823.00
IUUC-Gga-040997	Gallus gallus	71.96	0.00e+00	761.00
IUUC-Ggo-045238	Gorilla gorilla	65.37	0.00e+00	719.00
IUUC-Hsa-047039	Homo sapiens	69.22	0.00e+00	735.00
IUUC-Hvu-047815	Hordeum vulgare	30.18	4.00e-20	93.60
IUUC-Itr-048479	Ictidomys tridecemlineatus	69.41	0.00e+00	740.00
IUUC-Lch-049568	Latimeria chalumnae	72.37	0.00e+00	773.00
IUUC-Loc-052222	Lepisosteus oculatus	72.69	0.00e+00	743.00
IUUC-Laf-054499	Loxodonta africana	65.00	0.00e+00	714.00
IUUC-Meu-056879	Macropus eugenii	67.90	0.00e+00	716.00
IUUC-Mga-059971	Meleagris gallopavo	70.78	0.00e+00	746.00
IUUC-Mmr-060740	Microcebus murinus	69.02	0.00e+00	733.00
IUUC-Mdo-062192	Monodelphis domestica	69.22	0.00e+00	734.00
IUUC-Mmu-064241	Mus musculus	69.22	0.00e+00	735.00
IUUC-Mpu-066595	Mustela putorius furo	68.82	0.00e+00	731.00
IUUC-Mlu-067069	Myotis lucifugus	68.69	0.00e+00	731.00
IUUC-Opr-070472	Ochotona princeps	65.42	0.00e+00	714.00
IUUC-Ont-071711	Oreochromis niloticus	88.62	0.00e+00	929.00
IUUC-Ocu-074221	Oryctolagus cuniculus	68.69	0.00e+00	726.00
IUUC-Ola-087000	Oryzias latipes	83.53	0.00e+00	872.00
IUUC-Oga-088225	Otolemur garnettii	68.24	0.00e+00	726.00
IUUC-Oar-090244	Ovis aries	61.07	0.00e+00	686.00
IUUC-Pan-091804	Papio anubis	69.61	0.00e+00	739.00
IUUC-Psi-093252	Pelodiscus sinensis	63.88	0.00e+00	648.00
IUUC-Pfo-096542	Poecilia formosa	86.36	0.00e+00	925.00
IUUC-Pab-098168	Pongo abelii	73.51	0.00e+00	710.00
IUUC-Ppe-102072	Prunus persica	36.71	6.00e-26	112.00
IUUC-Rno-105542	Rattus norvegicus	69.02	0.00e+00	734.00
IUUC-Sha-107524	Sarcophilus harrisii	69.22	0.00e+00	735.00
IUUC-Stu-112331	Solanum tuberosum	33.16	6.00e-23	102.00
IUUC-Sar-113235	Sorex araneus	64.00	2.00e-176	612.00
IUUC-Ssc-115624	Sus scrofa	68.43	0.00e+00	727.00
IUUC-Tru-118559	Takifugu rubripes	82.97	0.00e+00	877.00
IUUC-Tni-119928	Tetraodon nigroviridis	75.00	0.00e+00	786.00
IUUC-Tca-121341	Theobroma cacao	36.76	1.00e-21	98.60
IUUC-Ttr-129002	Tursiops truncatus	62.78	0.00e+00	676.00
IUUC-Xtr-132224	Xenopus tropicalis	68.43	0.00e+00	715.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence