iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000020968.1	ENSOART00000022843.1	ENSOARP00000022533.1
ENSOARG00000020968.1	ENSOART00000022844.1	ENSOARP00000022534.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.10e-16	60.7	62	120

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           ++++v++l++y +++d++L ++k ++++++   eq+++W+k+++ ++g++G++P nFv+k++
   Q: 62   QDNLVIALHSYVPSHDGDLGFEKDEQLRIL---EQNGEWWKAQSLTTGQEGFIPFNFVAKAN 120
           6899**************************...**************************987 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MGCSCSSNPE DDWMENIDVC ENCHYPIVPL DGKTTLPMRN GSEVRDPLVT YEGSNPPASP 60
LQDNLVIALH SYVPSHDGDL GFEKDEQLRI LEQNGEWWKA QSLTTGQEGF IPFNFVAKAN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATGGCGGCT GGGGGGCTGA CAATCTCGGG CACTTCTGGA AGTTCCCAGG GCTAGGCCCT 60
AGCATGTCTG ATGTTCGGGG AGCCCTTTCA GCCCCCTCTC CATTCCCCCA GGGACCATGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0001772--C:immunological synapse
GO:0045121--C:membrane raft
GO:0000242--C:pericentriolar material
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0004722--F:protein serine/threonine phosphatase activity
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006882--P:cellular zinc ion homeostasis
GO:2001244--P:positive regulation of intrinsic apoptotic signaling pathway
GO:0050870--P:positive regulation of T cell activation
GO:0042493--P:response to drug
GO:0030217--P:T cell differentiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001315	Ailuropoda melanoleuca	82.34	0.00e+00	977.00
IUUC-Apl-004134	Anas platyrhynchos	70.84	0.00e+00	692.00
IUUC-Bta-013264	Bos taurus	89.27	0.00e+00	1021.00
IUUC-Cja-019574	Callithrix jacchus	94.97	0.00e+00	699.00
IUUC-Cfa-021161	Canis familiaris	82.68	0.00e+00	983.00
IUUC-Cpo-022492	Cavia porcellus	85.15	0.00e+00	970.00
IUUC-Csa-023270	Chlorocebus sabaeus	69.37	0.00e+00	752.00
IUUC-Dre-028005	Danio rerio	66.47	0.00e+00	683.00
IUUC-Dno-029365	Dasypus novemcinctus	83.18	0.00e+00	938.00
IUUC-Dor-030892	Dipodomys ordii	80.80	0.00e+00	895.00
IUUC-Eca-033325	Equus caballus	85.54	0.00e+00	966.00
IUUC-Eeu-035004	Erinaceus europaeus	77.80	0.00e+00	763.00
IUUC-Fca-035908	Felis catus	87.12	0.00e+00	998.00
IUUC-Gmo-038984	Gadus morhua	58.33	0.00e+00	667.00
IUUC-Gga-040997	Gallus gallus	74.06	0.00e+00	861.00
IUUC-Gac-041854	Gasterosteus aculeatus	61.61	0.00e+00	694.00
IUUC-Gma-043628	Glycine max	32.84	7.00e-21	95.90
IUUC-Ggo-045238	Gorilla gorilla	82.17	0.00e+00	973.00
IUUC-Hsa-047039	Homo sapiens	86.58	0.00e+00	989.00
IUUC-Hvu-047815	Hordeum vulgare	28.86	9.00e-21	95.50
IUUC-Itr-048479	Ictidomys tridecemlineatus	86.94	0.00e+00	994.00
IUUC-Lch-049568	Latimeria chalumnae	69.57	0.00e+00	811.00
IUUC-Laf-054499	Loxodonta africana	81.49	0.00e+00	963.00
IUUC-Mcc-054872	Macaca mulatta	68.88	0.00e+00	798.00
IUUC-Meu-056879	Macropus eugenii	82.24	0.00e+00	943.00
IUUC-Mtr-058765	Medicago truncatula	34.63	2.00e-20	94.40
IUUC-Mga-059971	Meleagris gallopavo	73.52	0.00e+00	852.00
IUUC-Mmr-060740	Microcebus murinus	86.58	0.00e+00	991.00
IUUC-Mdo-062192	Monodelphis domestica	83.54	0.00e+00	960.00
IUUC-Mmu-064241	Mus musculus	85.15	0.00e+00	979.00
IUUC-Mpu-066595	Mustela putorius furo	86.40	0.00e+00	989.00
IUUC-Mlu-067069	Myotis lucifugus	85.71	0.00e+00	979.00
IUUC-Opr-070472	Ochotona princeps	82.36	0.00e+00	968.00
IUUC-Ont-071711	Oreochromis niloticus	61.61	0.00e+00	672.00
IUUC-Ocu-074221	Oryctolagus cuniculus	86.76	0.00e+00	984.00
IUUC-Ola-087000	Oryzias latipes	61.29	0.00e+00	692.00
IUUC-Oga-088225	Otolemur garnettii	86.05	0.00e+00	985.00
IUUC-Ptr-090751	Pan troglodytes	97.14	0.00e+00	712.00
IUUC-Pan-091804	Papio anubis	86.05	0.00e+00	979.00
IUUC-Psi-093252	Pelodiscus sinensis	68.63	0.00e+00	778.00
IUUC-Pfo-096542	Poecilia formosa	60.85	0.00e+00	698.00
IUUC-Pab-098168	Pongo abelii	85.66	0.00e+00	934.00
IUUC-Pca-100547	Procavia capensis	80.59	3.00e-174	604.00
IUUC-Rno-105542	Rattus norvegicus	84.97	0.00e+00	978.00
IUUC-Sha-107524	Sarcophilus harrisii	83.36	0.00e+00	961.00
IUUC-Sar-113235	Sorex araneus	79.08	0.00e+00	823.00
IUUC-Ssc-115624	Sus scrofa	86.76	0.00e+00	994.00
IUUC-Tru-118559	Takifugu rubripes	59.72	0.00e+00	683.00
IUUC-Ttr-129002	Tursiops truncatus	79.63	0.00e+00	930.00
IUUC-Vvi-131057	Vitis vinifera	32.42	2.00e-22	101.00
IUUC-Xtr-132224	Xenopus tropicalis	67.98	0.00e+00	792.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence