iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000008436.1	ENSAMET00000009261.1	ENSAMEP00000008883.1
ENSAMEG00000008436.1	ENSAMET00000009272.1	ENSAMEP00000008893.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	9.80e-06	26.1	193	234

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiCle +   ++++v pC H fh++C+  w        ++ +CP Cr
   Q: 193  CAICLEKYidGEELRVIPCTHRFHRKCVDPW------LLQHHTCPHCR 234
           ********66334******************......9999******8 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MHPLGLCNNN DEEDLYEYGW VGVVKLEQPE LDPKPCLTVL GKAKRAVQRG ATAVIFDVSE 60
NPEAIDQLNQ GSEDPLKRPV VYVKGADAIK LMNIVNKQKV ARARIQHRPP RQPTEYFDMG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCACCCAC TGGGCCTGTG TAATAACAAC GATGAAGAGG ACTTGTATGA ATACGGCTGG 60
GTAGGCGTGG TGAAGCTGGA ACAGCCAGAA TTGGACCCGA AACCATGCCT CACTGTCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005887--C:integral component of plasma membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0060070--P:canonical Wnt signaling pathway
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:2000051--P:negative regulation of non-canonical Wnt signaling pathway
GO:0072089--P:stem cell proliferation
GO:0006511--P:ubiquitin-dependent protein catabolic process
GO:0038018--P:Wnt receptor catabolic process
GO:0060071--P:Wnt signaling pathway, planar cell polarity pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004188	Anas platyrhynchos	73.42	0.00e+00	1023.00
IUUC-Aca-004606	Anolis carolinensis	34.97	9.00e-27	114.00
IUUC-Aly-005850	Arabidopsis lyrata	42.68	3.00e-15	74.30
IUUC-Ath-007372	Arabidopsis thaliana	42.17	7.00e-15	73.20
IUUC-Ame-011764	Astyanax mexicanus	63.52	0.00e+00	727.00
IUUC-Bta-012478	Bos taurus	68.39	0.00e+00	692.00
IUUC-Cja-019504	Callithrix jacchus	86.30	0.00e+00	1285.00
IUUC-Cfa-020048	Canis familiaris	90.55	0.00e+00	1340.00
IUUC-Cpo-021725	Cavia porcellus	80.44	0.00e+00	1153.00
IUUC-Csa-023586	Chlorocebus sabaeus	86.54	0.00e+00	1223.00
IUUC-Cho-024867	Choloepus hoffmanni	91.18	0.00e+00	679.00
IUUC-Cin-025569	Ciona intestinalis	47.11	1.00e-55	210.00
IUUC-Csv-025869	Ciona savignyi	45.04	4.00e-49	189.00
IUUC-Dre-027553	Danio rerio	64.93	0.00e+00	799.00
IUUC-Dno-029370	Dasypus novemcinctus	83.92	0.00e+00	1187.00
IUUC-Dor-030816	Dipodomys ordii	78.34	0.00e+00	1085.00
IUUC-Ete-033060	Echinops telfairi	75.20	0.00e+00	845.00
IUUC-Eca-034044	Equus caballus	88.96	0.00e+00	1326.00
IUUC-Eeu-034591	Erinaceus europaeus	65.43	4.00e-139	488.00
IUUC-Fca-036000	Felis catus	91.46	0.00e+00	1362.00
IUUC-Fal-037147	Ficedula albicollis	71.07	0.00e+00	1023.00
IUUC-Gmo-039099	Gadus morhua	52.56	1.00e-121	430.00
IUUC-Gga-041243	Gallus gallus	68.12	0.00e+00	802.00
IUUC-Gac-041340	Gasterosteus aculeatus	50.70	1.00e-113	403.00
IUUC-Gma-044387	Glycine max	50.00	5.00e-15	73.90
IUUC-Ggo-044953	Gorilla gorilla	87.42	0.00e+00	1271.00
IUUC-Hsa-046484	Homo sapiens	87.52	0.00e+00	1280.00
IUUC-Itr-048470	Ictidomys tridecemlineatus	83.90	0.00e+00	1226.00
IUUC-Lch-050004	Latimeria chalumnae	59.89	0.00e+00	667.00
IUUC-Loc-051830	Lepisosteus oculatus	66.49	0.00e+00	771.00
IUUC-Laf-053975	Loxodonta africana	83.17	0.00e+00	1196.00
IUUC-Mcc-055302	Macaca mulatta	86.42	0.00e+00	1207.00
IUUC-Meu-056263	Macropus eugenii	74.69	0.00e+00	774.00
IUUC-Mtr-058744	Medicago truncatula	54.17	2.00e-13	68.20
IUUC-Mga-059706	Meleagris gallopavo	71.58	0.00e+00	1040.00
IUUC-Mmr-061372	Microcebus murinus	85.09	0.00e+00	1197.00
IUUC-Mdo-062651	Monodelphis domestica	66.02	0.00e+00	867.00
IUUC-Mmu-064339	Mus musculus	81.86	0.00e+00	1176.00
IUUC-Mac-065356	Musa acuminata	50.00	6.00e-13	68.20
IUUC-Mpu-066211	Mustela putorius furo	87.97	0.00e+00	1308.00
IUUC-Mlu-067058	Myotis lucifugus	89.16	0.00e+00	1236.00
IUUC-Nle-069886	Nomascus leucogenys	86.91	0.00e+00	1247.00
IUUC-Opr-070218	Ochotona princeps	80.31	0.00e+00	1036.00
IUUC-Ont-072483	Oreochromis niloticus	62.58	0.00e+00	773.00
IUUC-Oan-073718	Ornithorhynchus anatinus	71.57	0.00e+00	900.00
IUUC-Ocu-073847	Oryctolagus cuniculus	77.54	0.00e+00	1030.00
IUUC-Oba-075528	Oryza barthii	43.64	3.00e-12	66.20
IUUC-Ogl-077034	Oryza glaberrima	53.06	4.00e-11	62.00
IUUC-Oin-079182	Oryza indica	53.06	2.00e-11	63.20
IUUC-Oru-084953	Oryza rufipogon	53.06	3.00e-11	62.80
IUUC-Osa-085734	Oryza sativa	53.06	3.00e-11	62.80
IUUC-Ola-087358	Oryzias latipes	63.59	0.00e+00	775.00
IUUC-Oga-088362	Otolemur garnettii	85.09	0.00e+00	1285.00
IUUC-Oar-090197	Ovis aries	99.49	1.00e-96	347.00
IUUC-Ptr-091350	Pan troglodytes	87.27	0.00e+00	1277.00
IUUC-Pan-091700	Papio anubis	86.18	0.00e+00	1198.00
IUUC-Psi-093301	Pelodiscus sinensis	69.39	0.00e+00	967.00
IUUC-Pfo-096917	Poecilia formosa	63.91	0.00e+00	759.00
IUUC-Pab-097932	Pongo abelii	87.15	0.00e+00	1301.00
IUUC-Pop-099640	Populus trichocarpa	57.14	2.00e-14	72.40
IUUC-Pca-101054	Procavia capensis	91.85	0.00e+00	934.00
IUUC-Pva-102879	Pteropus vampyrus	89.35	0.00e+00	1326.00
IUUC-Pgr-103476	Puccinia graminis	41.27	3.00e-09	55.80
IUUC-Sha-106507	Sarcophilus harrisii	53.98	2.00e-164	572.00
IUUC-Sit-110656	Setaria italica	67.44	7.00e-13	66.60
IUUC-Stu-112500	Solanum tuberosum	62.79	5.00e-13	67.00
IUUC-Sar-113182	Sorex araneus	82.33	2.00e-112	400.00
IUUC-Sbi-114414	Sorghum bicolor	41.03	6.00e-13	66.60
IUUC-Ssc-115966	Sus scrofa	82.53	0.00e+00	1063.00
IUUC-Tgu-116864	Taeniopygia guttata	65.49	0.00e+00	662.00
IUUC-Tru-118502	Takifugu rubripes	61.85	0.00e+00	731.00
IUUC-Tsy-119210	Tarsius syrichta	84.85	0.00e+00	1204.00
IUUC-Tni-120344	Tetraodon nigroviridis	52.73	7.00e-122	431.00
IUUC-Tca-120966	Theobroma cacao	46.88	6.00e-13	68.60
IUUC-Tbe-127735	Tupaia belangeri	81.04	4.00e-124	438.00
IUUC-Ttr-128714	Tursiops truncatus	76.23	0.00e+00	1021.00
IUUC-Xtr-132280	Xenopus tropicalis	60.24	0.00e+00	685.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence